메뉴 건너뛰기




Volumn 121, Issue 11, 2011, Pages 409-413

Pathogenesis and pathophysiology of aortic valve stenosis in adults

Author keywords

Calcific aortic stenosis; Valvular heart disease

Indexed keywords

ANGIOTENSIN I; ANGIOTENSIN II; CYTOKINE; DIPEPTIDYL CARBOXYPEPTIDASE; MATRIX METALLOPROTEINASE; VASCULOTROPIN;

EID: 83055171417     PISSN: 00323772     EISSN: None     Source Type: Journal    
DOI: 10.20452/pamw.1103     Document Type: Review
Times cited : (23)

References (39)
  • 2
    • 80054937214 scopus 로고    scopus 로고
    • Calcific aortic valve disease: Not simply a degenerative process: A review and agenda for research from the national heart and lung and blood institute aortic stenosis working group executive summary: calcific aortic valve disease - 2011 update
    • Rajamannan NM, Evans FJ, Aikawa E, et al. Calcific aortic valve disease: not simply a degenerative process: a review and agenda for research from the national heart and lung and blood institute aortic stenosis working group executive summary: calcific aortic valve disease - 2011 update. Circulation. 2011; 124: 1783-1791.
    • (2011) Circulation. , vol.124 , pp. 1783-1791
    • Rajamannan, N.M.1    Evans, F.J.2    Aikawa, E.3
  • 3
    • 21044437380 scopus 로고    scopus 로고
    • Spectrum of calcific aortic valve disease: Pathogenesis, disease progression, and treatment strategies
    • DOI 10.1161/CIRCULATIONAHA.104.486738
    • Freeman RV, Otto CM. Spectrum of calcific aortic valve disease: pathogenesis, disease progression, and treatment strategies. Circulation. 2005; 111: 3316-3326. (Pubitemid 40875006)
    • (2005) Circulation , vol.111 , Issue.24 , pp. 3316-3326
    • Freeman, R.V.1    Otto, C.M.2
  • 4
    • 67349191480 scopus 로고    scopus 로고
    • Molecular and cellular mechanisms of aortic stenosis
    • Yetkin E, Waltenberger J. Molecular and cellular mechanisms of aortic stenosis. Int J Cardiol. 2009; 135: 4-13.
    • (2009) Int J Cardiol , vol.135 , pp. 4-13
    • Yetkin, E.1    Waltenberger, J.2
  • 6
    • 34648844242 scopus 로고    scopus 로고
    • Aortic valve stenosis: An active atheroinflammatory process
    • DOI 10.1097/MOL.0b013e3282a66099, PII 0004143320071000000002
    • Helske S, Kupari M, Lindstedt KA, Kovanen PT. Aortic valve stenosis: an active atheroinflammatory process. Curr Opin Lipidol. 2007; 18: 483-491. (Pubitemid 47462199)
    • (2007) Current Opinion in Lipidology , vol.18 , Issue.5 , pp. 483-491
    • Helske, S.1    Kupari, M.2    Lindstedt, K.A.3    Kovanen, P.T.4
  • 7
    • 59449092756 scopus 로고    scopus 로고
    • Calcific aortic stenosis: Lessons learned from experimental and clinical studies
    • Rajamannan NM. Calcific aortic stenosis: lessons learned from experimental and clinical studies. Arterioscler Thromb Vasc Biol. 2009; 29: 162-168.
    • (2009) Arterioscler Thromb Vasc Biol. , vol.29 , pp. 162-168
    • Rajamannan, N.M.1
  • 8
    • 64749086542 scopus 로고    scopus 로고
    • Aortic valve calcification: Basic science to clinical practice
    • Akat K, Borggrefe M, Kaden JJ. Aortic valve calcification: basic science to clinical practice. Heart. 2009; 95: 616-623.
    • (2009) Heart. , vol.95 , pp. 616-623
    • Akat, K.1    Borggrefe, M.2    Kaden, J.J.3
  • 9
    • 79958147911 scopus 로고    scopus 로고
    • Calcific aortic valve stenosis: Methods, models, and mechanisms
    • Miller JD, Weiss RM, Heistad DD. Calcific aortic valve stenosis: methods, models, and mechanisms. Circ Res. 2011; 108: 1392-1412.
    • (2011) Circ Res. , vol.108 , pp. 1392-1412
    • Miller, J.D.1    Weiss, R.M.2    Heistad, D.D.3
  • 10
    • 33644619491 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha promotes an osteoblast-like phenotype in human aortic valve myofibroblasts: A potential regulatory mechanism of valvular calcification
    • Kaden JJ, Kiliç R, Sarikoç A, et al. Tumor necrosis factor alpha promotes an osteoblast-like phenotype in human aortic valve myofibroblasts: a potential regulatory mechanism of valvular calcification. Int J Mol Med. 2005; 16: 869-872.
    • (2005) Int J Mol Med. , vol.16 , pp. 869-872
    • Kaden, J.J.1    Kiliç, R.2    Sarikoç, A.3
  • 11
    • 79960493929 scopus 로고    scopus 로고
    • Circulating activated and effector memory T cells are associated with calcification and clonal expansions in bicuspid and tricuspid valves of calcific aortic stenosis
    • Winchester R, Wiesendanger M, O'Brien W, et al. Circulating activated and effector memory T cells are associated with calcification and clonal expansions in bicuspid and tricuspid valves of calcific aortic stenosis. J Immunol. 2011; 187: 1006-1014.
    • (2011) J Immunol , vol.187 , pp. 1006-1014
    • Winchester, R.1    Wiesendanger, M.2    O'Brien, W.3
  • 12
    • 36348976915 scopus 로고    scopus 로고
    • The emerging role of valve interstitial cell phenotypes in regulating heart valve pathobiology
    • DOI 10.2353/ajpath.2007.070251
    • Liu AC, Joag VR, Gotlieb AI. The emerging role of valve interstitial cell phenotypes in regulating heart valve pathobiology. Am J Pathol. 2007; 171: 1407-1418. (Pubitemid 350158303)
    • (2007) American Journal of Pathology , vol.171 , Issue.5 , pp. 1407-1418
    • Liu, A.C.1    Joag, V.R.2    Gotlieb, A.I.3
  • 13
    • 79959510947 scopus 로고    scopus 로고
    • Osteopontin controls endothelial cell migration in vitro and in excised human valvular tissue from patients with Calcific Aortic Stenosis and controls
    • Dec 6. [Epub ahead of print]
    • Poggio P, Grau JB, Field BC, et al. Osteopontin controls endothelial cell migration in vitro and in excised human valvular tissue from patients with Calcific Aortic Stenosis and controls. J Cell Physiol. 2010 Dec 6. [Epub ahead of print].
    • (2010) J Cell Physiol
    • Poggio, P.1    Grau, J.B.2    Field, B.C.3
  • 14
    • 7044260650 scopus 로고    scopus 로고
    • Expression of bone sialoprotein and bone morphogenetic protein-2 in calcific aortic stenosis
    • Kaden JJ, Bickelhaupt S, Grobholz R, et al. Expression of bone sialoprotein and bone morphogenetic protein-2 in calcific aortic stenosis. J Heart Valve Dis. 2004; 13: 560-566.
    • (2004) J Heart Valve Dis. , vol.13 , pp. 560-566
    • Kaden, J.J.1    Bickelhaupt, S.2    Grobholz, R.3
  • 15
    • 79958828890 scopus 로고    scopus 로고
    • Cell-matrix interactions in the pathobiology of calcific aortic valve disease: Critical roles for matricellular, matricrine, and matrix mechanics cues
    • Chen JH, Simmons CA. Cell-matrix interactions in the pathobiology of calcific aortic valve disease: critical roles for matricellular, matricrine, and matrix mechanics cues. Circ Res. 2011; 108: 1510-1524.
    • (2011) Circ Res. , vol.108 , pp. 1510-1524
    • Chen, J.H.1    Simmons, C.A.2
  • 16
    • 67649411600 scopus 로고    scopus 로고
    • Correlation between plasma osteopontin levels and aortic valve calcification: Potential insights into the pathogenesis of aortic valve calcification and stenosis
    • Yu PJ, Skolnick A, Ferrari G, et al. Correlation between plasma osteopontin levels and aortic valve calcification: potential insights into the pathogenesis of aortic valve calcification and stenosis. J Thorac Cardiovasc Surg. 2009; 138: 196-199.
    • (2009) J Thorac Cardiovasc Surg. , vol.138 , pp. 196-199
    • Yu, P.J.1    Skolnick, A.2    Ferrari, G.3
  • 17
    • 3242781731 scopus 로고    scopus 로고
    • Clinical implications of the osteoprotegerin/RANKL/RANK system for bone and vascular diseases
    • DOI 10.1001/jama.292.4.490
    • Hofbauer LC, Schoppet M. Clinical implications of the osteoprotegerin/RANKL/RANK system for bone and vascular diseases. JAMA. 2004; 92: 490-495. (Pubitemid 38988958)
    • (2004) Journal of the American Medical Association , vol.292 , Issue.4 , pp. 490-495
    • Hofbauer, L.C.1    Schoppet, M.2
  • 18
    • 22144457305 scopus 로고    scopus 로고
    • A crucial role for reactive oxygen species in RANKL-induced osteoclast differentiation
    • DOI 10.1182/blood-2004-09-3662
    • Lee NK, Choi YG, Baik JY, et al. A crucial role for reactive oxygen species in rankl-induced osteoclast differentiation. Blood. 2005; 106: 852-859. (Pubitemid 41076424)
    • (2005) Blood , vol.106 , Issue.3 , pp. 852-859
    • Lee, N.K.1    Choi, Y.G.2    Baik, J.Y.3    Han, S.Y.4    Jeong, D.-W.5    Bae, Y.S.6    Kim, N.7    Lee, S.Y.8
  • 19
    • 0031039243 scopus 로고    scopus 로고
    • The biology of vascular endothelial growth factor
    • DOI 10.1210/er.18.1.4
    • Ferrara N, Davis-Smyth T. The biology of vascular endothelial growth factor. Endocr Rev. 1997; 18: 4-25. (Pubitemid 27076453)
    • (1997) Endocrine Reviews , vol.18 , Issue.1 , pp. 4-25
    • Ferrara, N.1    Davis-Smyth, T.2
  • 20
    • 0030695252 scopus 로고    scopus 로고
    • Modulation of growth factor action: Implications for the treatment of cardiovascular diseases
    • Waltenberger J. Modulation of growth factor action: implications for the treatment of cardiovascular diseases. Circulation. 1997; 96: 4083-4094.
    • (1997) Circulation. , vol.96 , pp. 4083-4094
    • Waltenberger, J.1
  • 21
    • 79952134815 scopus 로고    scopus 로고
    • β-catenin mediates mechanically regulated, transforming growth factor-β1-induced myofibroblast differentiation of aortic valve interstitial cells
    • Chen JH, Chen WL, Sider KL, et al. β-catenin mediates mechanically regulated, transforming growth factor-β1-induced myofibroblast differentiation of aortic valve interstitial cells. Arterioscler Thromb Vasc Biol. 2011; 31: 590-597.
    • (2011) Arterioscler Thromb Vasc Biol. , vol.31 , pp. 590-597
    • Chen, J.H.1    Chen, W.L.2    Sider, K.L.3
  • 22
    • 0037314647 scopus 로고    scopus 로고
    • Progression of aortic valve stenosis: TGF-beta1 is present in calcified aortic valve cusps and promotes aortic valve interstitial cell calcification via apoptosis
    • DOI 10.1016/S0003-4975(02)04312-6, PII S0003497502043126
    • Jian B, Narula N, Li QY, et al. Progression of aortic valve stenosis: TGF-beta1 is present in calcified aortic valve cusps and promotes aortic valve interstitial cell calcification via apoptosis. Ann Thorac Surg. 2003; 75: 457-465. (Pubitemid 36184488)
    • (2003) Annals of Thoracic Surgery , vol.75 , Issue.2 , pp. 457-465
    • Jian, B.1    Narula, N.2    Li, Q.-Y.3    Mohler III, E.R.4    Levy, R.J.5
  • 23
    • 0041386133 scopus 로고    scopus 로고
    • Angiogenesis is involved in the pathogenesis of nonrheumatic aortic valve stenosis
    • DOI 10.1016/S0046-8177(03)00245-4
    • Soini Y, Salo T, Satta J. Angiogenesis is involved in the pathogenesis of nonrheumatic aortic valve stenosis. Hum Pathol. 2003; 34: 756-763. (Pubitemid 37040610)
    • (2003) Human Pathology , vol.34 , Issue.8 , pp. 756-763
    • Soini, Y.1    Salo, T.2    Satta, J.3
  • 24
    • 0041328399 scopus 로고    scopus 로고
    • Evidence for an altered balance between matrix metalloproteinase-9 and its inhibitors in calcific aortic stenosis
    • DOI 10.1016/S0003-4975(03)00529-0, PII S0003497503005290
    • Satta J, Oiva J, Salo T, et al. Evidence for an altered balance between matrix metalloproteinase-9 and its inhibitors in calcific aortic stenosis. Ann Thorac Surg. 2003; 76: 681-688. (Pubitemid 37100721)
    • (2003) Annals of Thoracic Surgery , vol.76 , Issue.3 , pp. 681-688
    • Satta, J.1    Oiva, J.2    Salo, T.3    Eriksen, H.4    Ohtonen, P.5    Biancari, F.6    Juvonen, T.S.7    Soini, Y.8
  • 28
    • 77956018766 scopus 로고    scopus 로고
    • Paraoxonase activity might be predictive of the severity of aortic valve stenosis
    • Cagirci G, Cay S, Karakurt O, et al. Paraoxonase activity might be predictive of the severity of aortic valve stenosis. J Heart Valve Dis. 2010; 19: 453-458.
    • (2010) J Heart Valve Dis. , vol.19 , pp. 453-458
    • Cagirci, G.1    Cay, S.2    Karakurt, O.3
  • 29
    • 79955714207 scopus 로고    scopus 로고
    • Bicuspid aortic valve disease: The role of oxidative stress in Lrp5 bone formation
    • Rajamannan NM. Bicuspid aortic valve disease: the role of oxidative stress in Lrp5 bone formation. Cardiovasc Pathol. 2011; 20: 168-176.
    • (2011) Cardiovasc Pathol. , vol.20 , pp. 168-176
    • Rajamannan, N.M.1
  • 31
    • 0142053965 scopus 로고    scopus 로고
    • Association Between Apolipoprotein E Alleles and Calcific Valvular Heart Disease
    • DOI 10.1161/01.CIR.0000097560.96431.3E
    • Novaro GM, Sachar R, Pearce GL, et al. Association between apolipoprotein E alleles and calcific valvular heart disease. Circulation. 2003; 108: 1804-1808. (Pubitemid 37296088)
    • (2003) Circulation , vol.108 , Issue.15 , pp. 1804-1808
    • Novaro, G.M.1    Sachar, R.2    Pearce, G.L.3    Sprecher, D.L.4    Griffin, B.P.5
  • 32
    • 0034768262 scopus 로고    scopus 로고
    • The vitamin D receptor genotype predisposes to the development of calcific aortic valve stenosis
    • Ortlepp JR, Hoffmann R, Ohme F, et al. The vitamin D receptor genotype predisposes to the development of calcific aortic valve stenosis. Heart. 2001; 85: 635-638. (Pubitemid 32973456)
    • (2001) Heart , vol.85 , Issue.6 , pp. 635-638
    • Ortlepp, J.R.1    Hoffmann, R.2    Ohme, F.3    Lauscher, J.4    Bleckmann, F.5    Hanrath, P.6
  • 33
    • 53449096148 scopus 로고    scopus 로고
    • Age-related changes in the aortic valve affect leaflet stress distributions: Implications for aortic valve degeneration
    • Singh R, Strom JA, Ondrovic L, et al. Age-related changes in the aortic valve affect leaflet stress distributions: implications for aortic valve degeneration. J Heart Valve Dis. 2008; 17: 290-298.
    • (2008) J Heart Valve Dis. , vol.17 , pp. 290-298
    • Singh, R.1    Strom, J.A.2    Ondrovic, L.3
  • 34
    • 59749083468 scopus 로고    scopus 로고
    • Reduced number and function of endothelial progenitor cells in patients with aortic valve stenosis: A novel concept for valvular endothelial cell repair
    • Matsumoto Y, Adams V, Walther C, et al. Reduced number and function of endothelial progenitor cells in patients with aortic valve stenosis: a novel concept for valvular endothelial cell repair. Eur Heart J. 2009; 30: 346-355.
    • (2009) Eur Heart J , vol.30 , pp. 346-355
    • Matsumoto, Y.1    Adams, V.2    Walther, C.3
  • 37
    • 58149204388 scopus 로고    scopus 로고
    • Echocardiographic assessment of valve stenosis EAE/ASE recommendations of clinical practice
    • Baumgartner H, Hung J, Bermejo J, et al. Echocardiographic assessment of valve stenosis EAE/ASE recommendations of clinical practice. J Am Soc Echocardiogr. 2009; 22: 1-23.
    • (2009) J Am Soc Echocardiogr. , vol.22 , pp. 1-23
    • Baumgartner, H.1    Hung, J.2    Bermejo, J.3
  • 38
    • 85080594268 scopus 로고    scopus 로고
    • Aortic stenosis and angiodysplastic gastrointestinal bleeding: Heyde's disease
    • Oct 11. [Epub ahead of print]
    • Islam S, Islam E, Cevik C, et al. Aortic stenosis and angiodysplastic gastrointestinal bleeding: Heyde's disease. Heart Lung. 2011 Oct 11. [Epub ahead of print].
    • (2011) Heart Lung
    • Islam, S.1    Islam, E.2    Cevik, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.