Age-related changes in the aortic valve affect leaflet stress distributions: Implications for aortic valve degeneration

Journal of Heart Valve Disease

Volumn 17, Issue 3, 2008, Pages 290-299

  Singh, Reetu ^a   Strom, Joel A ^a,b   Ondrovic, Leo ^a,b   Joseph, Babu ^a   Van Auker, Michael D ^a  

^a University of South Florida   (United States)

^b UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; AGING; AORTA VALVE; AORTA VALVE STENOSIS; ARTICLE; BIOLOGICAL MODEL; BIOMECHANICS; DISEASE COURSE; ELASTICITY; FINITE ELEMENT ANALYSIS; HEART VALVE PROSTHESIS; HUMAN; MECHANICAL STRESS; MIDDLE AGED; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PROSTHESIS; RISK FACTOR;

ADULT; AGED; AGED, 80 AND OVER; AGING; AORTIC VALVE; AORTIC VALVE STENOSIS; BIOMECHANICS; DISEASE PROGRESSION; ELASTICITY; FINITE ELEMENT ANALYSIS; HEART VALVE PROSTHESIS; HUMANS; MIDDLE AGED; MODELS, CARDIOVASCULAR; PROSTHESIS DESIGN; RISK FACTORS; STRESS, MECHANICAL;

EID: 53449096148     PISSN: 09668519     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (43)

1. Otto CM. Valvular Heart Disease. WB Saunders Co., Philadelphia, 1999:20
2. Passik CS, Ackermann DM, Pluth JR, Edwards WD. Temporal changes in the causes of aortic stenosis: A surgical pathologic study of 646 cases. Mayo Clin Proc 1987;62:119-123 (Pubitemid 17016453)
3. Dare AJ, Veinot JP, Edwards WD, Tazellar HD, Schaff HV. New observations on the etiology of aortic valve disease: A surgical pathologic study of 236 cases from 1990. Hum Pathol 1993;24:1330-1338 (Pubitemid 24033736)
4. Stewart BF, Siscovick D, Lind BK, et al. Clinical factors associated with calcific aortic valve disease. J Am Coll Cardiol 1997;29:630-634 (Pubitemid 27116107)
5. Lindroos M, Kupari M, Heikkila J, Tilvis R. Prevalence of aortic valve abnormalities in the elderly: An echocardiographic study of a random population sample. J Am Coll Cardiol 1993;21:1221-1225
6. Deck JD, Thubrikar MJ, Schneider PJ, Nolan SP. Structure, stress, and tissue repair in aortic valve leaflets. Cardiovasc Res 1988;22:7-16 (Pubitemid 18034770)
7. Thubrikar MJ, Deck JD, Aouad J, Nolan SP. Role of mechanical stresses in calcification of aortic bioprosthetic valves. J Thorac Cardiovasc Surg 1986;86:115-125
8. Thubrikar M. The Aortic Valve. CRC Press, Boca Raton, FL, 1990:8-17, 48-52, 66-70, 164-171
9. Sabbah HN, Hamid MS, Stein PD. Estimation of mechanical stresses on closed cusps of porcine bioprosthetic valves: Effects of stiffening, focal calcium and focal thinning. Am J Cardiol 1985;55:1091-1096. (Pubitemid 15085369)
10. Vesely I, Boughner DR, Song T. Tissue buckling as a mechanism of bioprosthetic valve failure. Ann Thorac Surg 1988;46:302-308
11. Vesely I, Noseworthy R. Micromechanics of the fibrosa and the ventricularis in aortic valve leaflets. J Biomech 1992;25:101-113
12. Wright JEC, Ng YL. Elasticity of human aortic valve cusps. Cardiovasc Res 1974;8:384-390
13. Christie GW, Barratt-Boyce BG. Age-dependent changes in radial stretch of human aortic valve leaflets determined by biaxial testing. Ann Thorac Surg 1995;60:156-159
14. Sahasakul Y, Edwards WD, Naessens JM, Tajik AJ. Age-related changes in aortic and mitral valve thicknesses: Implications for two dimensional echocardiography based on a normal study of 200 human hearts. Am J Cardiol 1988;62:424-430
15. Diamant J, Keller A, Baer E, Litt M, Arridge RGC. Collagen: Ultrastructure and its relation to mechanical properties as a function of ageing. Proc R Soc Lond B Biol Sci 1972;180:293-315
16. Kalath S, Tsipouras P, Silver FH. Non-invasive assessment of aortic mechanical properties. Ann Biomed Eng 1986;14:513-524 (Pubitemid 17228408)
17. Grande KJ, Cochran RP, Reinhall PG, Kunzelman KS. Stress Variations in the human aortic root and valve: The role of anatomic asymmetry. Ann Biomed Eng 1998;26:534-545 (Pubitemid 128609653)
18. Hamid MS, Sabbah HN, Stein PD. Influence of stent height upon stresses on the cusps of closed bioprosthetic valves. J Biomech 1986;19:759-769
19. Gnyaneshwar R, Kumar RK, Balakrishnan KR. Dynamic analysis of the aortic valve using a finite element model. Ann Thorac Surg 2002;73:1122-1129 (Pubitemid 34275890)
20. Howard IC, Patterson EA, Yoxall A. On the opening mechanism of the aortic valve: Some observations from simulations. J Med Eng Technol 2003;27:259-266 (Pubitemid 37485512)
21. Ranga A, Mongrain R, Mendes-Galaz R, Biadillah Y, Carrier R. Large displacement 3-D structural analysis of an aortic valve model with non-linear material properties. J Med Eng Technol 2004;28:95-103 (Pubitemid 38608491)
22. De Hart J, Cacciola G, Schreurs PJG, Peters GWM. A three-dimensional analysis of a fibre-reinforced aortic valve prosthesis. J Biomech 1998;31:629-638 (Pubitemid 28470515)
23. Beck A, Thubrikar MJ, Robiscek F. Stress analysis of the aortic valve with and without the sinuses of Valsalva. J Heart Valve Dis 2001;10:1-11 (Pubitemid 32104457)
24. Grande-Allen KJ, Cochran RP, Reinhall PG, Kunzelman KS. Finite-element analysis of aortic valve-sparing: Influence of graft shape and stiffness. IEEE Trans Biomed Eng 2001;48:647-659 (Pubitemid 32510049)
25. Grande-Allen KJ, Cochran RP, Reinhall PG, Kunzelman KS. Re-creation of sinuses is important for sparing the aortic valve: A finite element study. J Thorac Cardiovasc Surg 2000;119:753-763 (Pubitemid 30395473)
26. Grande KJ, Cochran RP, Reinhall PG, Kunzelman KS. Mechanisms of aortic valve incompetence: Finite element modeling of aortic root dilatation. Ann Thorac Surg 2000;69:1851-1857 (Pubitemid 30445533)
27. Grande-Allen KJ, Cochran RP, Reinhall PG, Kunzelman KS. Mechanisms of aortic valve incompetence: Finite-element modeling of Marfan syndrome. J Thorac Cardiovasc Surg 2001;122:946-954
28. Grande KJ, Cochran RP, Reinhall PG, Kunzelman KS. Mechanisms of aortic valve incompetence in aging: A finite element model. J Heart Valve Dis 1999;8:149-156 (Pubitemid 29166805)
29. Driessen NJB, Boerboom RA, Huyghe JMRH, Bouten CVC, Baaijens FPT. Computational analyses of mechanically induced collagen fiber remodeling in the aortic heart valve. J Biomech Eng 2003:549-557 (Pubitemid 37012215)
30. Kim H, Lu J, Sacks MS, Chandran KB. Dynamic simulation pericardial bioprosthetic heart valve function. J Biomech Eng 2006;128:717-724 (Pubitemid 44622800)
31. Kim H, Chandran KB, Sacks MS, Lu J. An experimentally derived stress resultant shell model for heart valve dynamic simulations. Ann Biomed Eng 2007;35:30-44 (Pubitemid 44916314)
32. Thubrikar MJ, Aouad J, Nolan SP. Patterns of calcific deposits in operatively excised stenotic or purely regurgitant aortic valves and their relation to mechanical stress. Am J Cardiol 1986;58:304-308 (Pubitemid 16052723)
33. De Hart J, Peters GW, Schreurs PJ, Baaijens FPT. A three-dimensional computational analysis of fluidstructure interaction in the aortic valve. J Biomech 2003;36:103-112 (Pubitemid 35448099)
34. Labrosse MR, Beller CJ, Robicsek F, Thubrikar MJ. Geometric modeling of functional trileaflet aortic valves: Development and clinical applications. J Biomech 2006;39:2665-2672 (Pubitemid 44468397)
35. Swanson WM, Clark RE. Dimensions and geometric relationships of the human aortic valve as a function of pressure. Circ Res 1974;35:871-882
36. Thubrikar M, Piepgrass WC, Bosher PL, Nolan SP. The elastic modulus of canine aortic valve leaflets in-vitro and in-vivo. Circ Res 1980;47:792-800 (Pubitemid 11238278)
37. Driscol TE, Eckstein RW. Systolic pressure gradients across the aortic valve an in the ascending aorta. Am J Physiol 1965;209:557-563
38. Thubrikar M, Bosher LP, Nolan SP. The mechanism of opening of the aortic valve. J Thorac Cardiovasc Surg 1979;77:863-870 (Pubitemid 10208453)
39. Carmody CJ, Burriesci G, Howard IC, Patterson EA. An approach to the simulation of fluid-structure interaction in the aortic valve. J Biomech 2006;39:158-169 (Pubitemid 41585021)
40. De Hart J, Peters GWM, Schreurs PJG, Baaijens FPT. Collagen fibers reduce stresses and stabilize motion of aortic valve leaflets during systole. J Biomech 2004;37:303-311 (Pubitemid 38156078)
41. Pinto ER, Damani PM, Sternberg CN, Liedtke AJ. Fine flutterings of the aortic valve as demonstrated by aortic valve echocardiograms. Am Heart J 1978;95:807-808 (Pubitemid 9006522)
42. Kunzelman KS, Quick DW, Cochran RP. Altered collagen in the mitral valve leaflets: biochemical and finite element analysis. Ann Thorac Surg 1998;66:S198-S205 (Pubitemid 29087161)
43. Quick DW, Kunzelman KS, Kneebone JM, Cochran RP. Collagen synthesis is upregulated in mitral valves subject to altered stress. Am Soc Artif Intern Organs J 1997;42:181-186 (Pubitemid 27209181)