메뉴 건너뛰기




Volumn 23, Issue 6, 2011, Pages 746-753

Diabetogenic T lymphocytes in human Type 1 diabetes

Author keywords

[No Author keywords available]

Indexed keywords

AMYLIN; CHEMOKINE RECEPTOR CXCR3; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GLUTAMATE DECARBOXYLASE; GLUTAMATE DECARBOXYLASE 65; HLA B ANTIGEN; INSULIN; INTERLEUKIN 17; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR ALPHA;

EID: 82955247941     PISSN: 09527915     EISSN: 18790372     Source Type: Journal    
DOI: 10.1016/j.coi.2011.10.001     Document Type: Review
Times cited : (77)

References (72)
  • 2
    • 80051473845 scopus 로고    scopus 로고
    • Anti-CD3 antibodies for type 1 diabetes: beyond expectations
    • Bach J.F. Anti-CD3 antibodies for type 1 diabetes: beyond expectations. Lancet 2011, 378:459-460.
    • (2011) Lancet , vol.378 , pp. 459-460
    • Bach, J.F.1
  • 6
    • 0022475906 scopus 로고
    • The histopathology of the pancreas in type 1 (insulin-dependent) diabetes mellitus: a 25-year review of deaths in patients under 20 years of age in the United Kingdom
    • Foulis A.K., Liddle C.N., Farquharson M.A., Richmond J.A., Weir R.S. The histopathology of the pancreas in type 1 (insulin-dependent) diabetes mellitus: a 25-year review of deaths in patients under 20 years of age in the United Kingdom. Diabetologia 1986, 29:267-274.
    • (1986) Diabetologia , vol.29 , pp. 267-274
    • Foulis, A.K.1    Liddle, C.N.2    Farquharson, M.A.3    Richmond, J.A.4    Weir, R.S.5
  • 9
    • 20044375937 scopus 로고    scopus 로고
    • A single course of anti-CD3 monoclonal antibody hOKT3gamma1(Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes
    • Herold K.C., Gitelman S.E., Masharani U., Hagopian W., Bisikirska B., Donaldson D., Rother K., Diamond B., Harlan D.M., Bluestone J.A. A single course of anti-CD3 monoclonal antibody hOKT3gamma1(Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes. Diabetes 2005, 54:1763-1769.
    • (2005) Diabetes , vol.54 , pp. 1763-1769
    • Herold, K.C.1    Gitelman, S.E.2    Masharani, U.3    Hagopian, W.4    Bisikirska, B.5    Donaldson, D.6    Rother, K.7    Diamond, B.8    Harlan, D.M.9    Bluestone, J.A.10
  • 10
    • 77949266510 scopus 로고    scopus 로고
    • Four-year metabolic outcome of a randomised controlled CD3-antibody trial in recent-onset type 1 diabetic patients depends on their age and baseline residual beta cell mass
    • Keymeulen B., Walter M., Mathieu C., Kaufman L., Gorus F., Hilbrands R., Vandemeulebroucke E., Van de Velde U., Crenier L., De Block C., et al. Four-year metabolic outcome of a randomised controlled CD3-antibody trial in recent-onset type 1 diabetic patients depends on their age and baseline residual beta cell mass. Diabetologia 2010, 53:614-623.
    • (2010) Diabetologia , vol.53 , pp. 614-623
    • Keymeulen, B.1    Walter, M.2    Mathieu, C.3    Kaufman, L.4    Gorus, F.5    Hilbrands, R.6    Vandemeulebroucke, E.7    Van de Velde, U.8    Crenier, L.9    De Block, C.10
  • 13
    • 33847629171 scopus 로고    scopus 로고
    • Translational mini-review series on type 1 diabetes: systematic analysis of T cell epitopes in autoimmune diabetes
    • Di Lorenzo T.P., Peakman M., Roep B.O. Translational mini-review series on type 1 diabetes: systematic analysis of T cell epitopes in autoimmune diabetes. Clin Exp Immunol 2007, 148:1-16.
    • (2007) Clin Exp Immunol , vol.148 , pp. 1-16
    • Di Lorenzo, T.P.1    Peakman, M.2    Roep, B.O.3
  • 15
    • 33847617787 scopus 로고    scopus 로고
    • Translational mini-review series on type 1 diabetes: immune-based therapeutic approaches for type 1 diabetes
    • Staeva-Vieira T., Peakman M., von Herrath M. Translational mini-review series on type 1 diabetes: immune-based therapeutic approaches for type 1 diabetes. Clin Exp Immunol 2007, 148:17-31.
    • (2007) Clin Exp Immunol , vol.148 , pp. 17-31
    • Staeva-Vieira, T.1    Peakman, M.2    von Herrath, M.3
  • 19
    • 0029120042 scopus 로고
    • Relationship of the 37,000- and 40,000-M(r) tryptic fragments of islet antigens in insulin-dependent diabetes to the protein tyrosine phosphatase-like molecule IA-2 (ICA512)
    • Payton M.A., Hawkes C.J., Christie M.R. Relationship of the 37,000- and 40,000-M(r) tryptic fragments of islet antigens in insulin-dependent diabetes to the protein tyrosine phosphatase-like molecule IA-2 (ICA512). J Clin Invest 1995, 96:1506-1511.
    • (1995) J Clin Invest , vol.96 , pp. 1506-1511
    • Payton, M.A.1    Hawkes, C.J.2    Christie, M.R.3
  • 20
    • 0025841845 scopus 로고
    • Identification and cloning of a granule autoantigen (carboxypeptidase-H) associated with type I diabetes
    • Castano L., Russo E., Zhou L., Lipes M.A., Eisenbarth G.S. Identification and cloning of a granule autoantigen (carboxypeptidase-H) associated with type I diabetes. J Clin Endocrinol Metab 1991, 73:1197-1201.
    • (1991) J Clin Endocrinol Metab , vol.73 , pp. 1197-1201
    • Castano, L.1    Russo, E.2    Zhou, L.3    Lipes, M.A.4    Eisenbarth, G.S.5
  • 25
    • 77956360380 scopus 로고    scopus 로고
    • Antigen-specific immunotherapy for type 1 diabetes: maximizing the potential
    • Peakman M., von Herrath M. Antigen-specific immunotherapy for type 1 diabetes: maximizing the potential. Diabetes 2010, 59:2087-2093.
    • (2010) Diabetes , vol.59 , pp. 2087-2093
    • Peakman, M.1    von Herrath, M.2
  • 27
    • 75649134941 scopus 로고    scopus 로고
    • Surrogate end points in the design of immunotherapy trials: emerging lessons from type 1 diabetes
    • Roep B.O., Peakman M. Surrogate end points in the design of immunotherapy trials: emerging lessons from type 1 diabetes. Nat Rev Immunol 2010, 10:145-152.
    • (2010) Nat Rev Immunol , vol.10 , pp. 145-152
    • Roep, B.O.1    Peakman, M.2
  • 30
    • 0029043041 scopus 로고
    • Detailed motifs for peptide binding to HLA-A*0201 derived from large random sets of peptides using a cellular binding assay
    • Drijfhout J.W., Brandt R.M., D'Amaro J., Kast W.M., Melief C.J. Detailed motifs for peptide binding to HLA-A*0201 derived from large random sets of peptides using a cellular binding assay. Hum Immunol 1995, 43:1-12.
    • (1995) Hum Immunol , vol.43 , pp. 1-12
    • Drijfhout, J.W.1    Brandt, R.M.2    D'Amaro, J.3    Kast, W.M.4    Melief, C.J.5
  • 32
    • 0028052724 scopus 로고
    • Scheme for ranking potential HLA-A2 binding peptides based on independent binding of individual peptide side-chains
    • Parker K.C., Bednarek M.A., Coligan J.E. Scheme for ranking potential HLA-A2 binding peptides based on independent binding of individual peptide side-chains. J Immunol 1994, 152:163-175.
    • (1994) J Immunol , vol.152 , pp. 163-175
    • Parker, K.C.1    Bednarek, M.A.2    Coligan, J.E.3
  • 33
    • 0027439013 scopus 로고
    • An autoantigenic T cell epitope forms unstable complexes with class II MHC: a novel route for escape from tolerance induction
    • Fairchild P.J., Wildgoose R., Atherton E., Webb S., Wraith D.C. An autoantigenic T cell epitope forms unstable complexes with class II MHC: a novel route for escape from tolerance induction. Int Immunol 1993, 5:1151-1158.
    • (1993) Int Immunol , vol.5 , pp. 1151-1158
    • Fairchild, P.J.1    Wildgoose, R.2    Atherton, E.3    Webb, S.4    Wraith, D.C.5
  • 35
    • 70449470318 scopus 로고    scopus 로고
    • Structural alterations in peptide-MHC recognition by self-reactive T cell receptors
    • Wucherpfennig K.W., Call M.J., Deng L., Mariuzza R. Structural alterations in peptide-MHC recognition by self-reactive T cell receptors. Curr Opin Immunol 2009, 21:590-595.
    • (2009) Curr Opin Immunol , vol.21 , pp. 590-595
    • Wucherpfennig, K.W.1    Call, M.J.2    Deng, L.3    Mariuzza, R.4
  • 37
    • 48249157055 scopus 로고    scopus 로고
    • Weak proinsulin peptide-major histocompatibility complexes are targeted in autoimmune diabetes in mice
    • Levisetti M.G., Lewis D.M., Suri A., Unanue E.R. Weak proinsulin peptide-major histocompatibility complexes are targeted in autoimmune diabetes in mice. Diabetes 2008, 57:1852-1860.
    • (2008) Diabetes , vol.57 , pp. 1852-1860
    • Levisetti, M.G.1    Lewis, D.M.2    Suri, A.3    Unanue, E.R.4
  • 38
    • 34248233148 scopus 로고    scopus 로고
    • The insulin-specific T cells of nonobese diabetic mice recognize a weak MHC-binding segment in more than one form
    • Levisetti M.G., Suri A., Petzold S.J., Unanue E.R. The insulin-specific T cells of nonobese diabetic mice recognize a weak MHC-binding segment in more than one form. J Immunol 2007, 178:6051-6057.
    • (2007) J Immunol , vol.178 , pp. 6051-6057
    • Levisetti, M.G.1    Suri, A.2    Petzold, S.J.3    Unanue, E.R.4
  • 41
    • 0033865109 scopus 로고    scopus 로고
    • Driver clones and determinant spreading
    • Sercarz E.E. Driver clones and determinant spreading. J Autoimmun 2000, 14:275-277.
    • (2000) J Autoimmun , vol.14 , pp. 275-277
    • Sercarz, E.E.1
  • 47
    • 0023520177 scopus 로고
    • Immunoreactive alpha-interferon in insulin-secreting beta cells in type 1 diabetes mellitus
    • Foulis A.K., Farquharson M.A., Meager A. Immunoreactive alpha-interferon in insulin-secreting beta cells in type 1 diabetes mellitus. Lancet 1987, 2:1423-1427.
    • (1987) Lancet , vol.2 , pp. 1423-1427
    • Foulis, A.K.1    Farquharson, M.A.2    Meager, A.3
  • 49
    • 77949510984 scopus 로고    scopus 로고
    • The role of perforin and granzymes in diabetes
    • Thomas H.E., Trapani J.A., Kay T.W. The role of perforin and granzymes in diabetes. Cell Death Differ 2010, 17:577-585.
    • (2010) Cell Death Differ , vol.17 , pp. 577-585
    • Thomas, H.E.1    Trapani, J.A.2    Kay, T.W.3
  • 50
    • 33845533220 scopus 로고    scopus 로고
    • Identification of Novel HLA-A*0201-restricted epitopes in recent-onset type 1 diabetic subjects and antibody-positive relatives
    • Standifer N.E., Ouyang Q., Panagiotopoulos C., Verchere C.B., Tan R., Greenbaum C.J., Pihoker C., Nepom G.T. Identification of Novel HLA-A*0201-restricted epitopes in recent-onset type 1 diabetic subjects and antibody-positive relatives. Diabetes 2006, 55:3061-3067.
    • (2006) Diabetes , vol.55 , pp. 3061-3067
    • Standifer, N.E.1    Ouyang, Q.2    Panagiotopoulos, C.3    Verchere, C.B.4    Tan, R.5    Greenbaum, C.J.6    Pihoker, C.7    Nepom, G.T.8
  • 51
    • 67650079482 scopus 로고    scopus 로고
    • Etanercept treatment in children with new-onset type 1 diabetes: pilot randomized, placebo-controlled, double-blind study
    • Mastrandrea L., Yu J., Behrens T., Buchlis J., Albini C., Fourtner S., Quattrin T. Etanercept treatment in children with new-onset type 1 diabetes: pilot randomized, placebo-controlled, double-blind study. Diabetes Care 2009, 32:1244-1249.
    • (2009) Diabetes Care , vol.32 , pp. 1244-1249
    • Mastrandrea, L.1    Yu, J.2    Behrens, T.3    Buchlis, J.4    Albini, C.5    Fourtner, S.6    Quattrin, T.7
  • 52
    • 0030731917 scopus 로고    scopus 로고
    • Nitric oxide primes pancreatic beta cells for Fas-mediated destruction in insulin-dependent diabetes mellitus
    • Stassi G., De Maria R., Trucco G., Rudert W., Testi R., Galluzzo A., Giordano C., Trucco M. Nitric oxide primes pancreatic beta cells for Fas-mediated destruction in insulin-dependent diabetes mellitus. J Exp Med 1997, 186:1193-1200.
    • (1997) J Exp Med , vol.186 , pp. 1193-1200
    • Stassi, G.1    De Maria, R.2    Trucco, G.3    Rudert, W.4    Testi, R.5    Galluzzo, A.6    Giordano, C.7    Trucco, M.8
  • 53
    • 0033178741 scopus 로고    scopus 로고
    • Evidence that beta cell death in the nonobese diabetic mouse is Fas independent
    • Thomas H.E., Darwiche R., Corbett J.A., Kay T.W. Evidence that beta cell death in the nonobese diabetic mouse is Fas independent. J Immunol 1999, 163:1562-1569.
    • (1999) J Immunol , vol.163 , pp. 1562-1569
    • Thomas, H.E.1    Darwiche, R.2    Corbett, J.A.3    Kay, T.W.4
  • 54
    • 67649364114 scopus 로고    scopus 로고
    • The role of inflammation in insulitis and beta-cell loss in type 1 diabetes
    • Eizirik D.L., Colli M.L., Ortis F. The role of inflammation in insulitis and beta-cell loss in type 1 diabetes. Nat Rev Endocrinol 2009, 5:219-226.
    • (2009) Nat Rev Endocrinol , vol.5 , pp. 219-226
    • Eizirik, D.L.1    Colli, M.L.2    Ortis, F.3
  • 55
    • 80052829943 scopus 로고    scopus 로고
    • Peripheral and islet interleukin-17 pathway activation characterizes human autoimmune diabetes and promotes cytokine-mediated {beta}-cell death
    • Arif S., Moore F., Marks K., Bouckenooghe T., Dayan C.M., Planas R., Vives-Pi M., Powrie J., Tree T., Marchetti P., et al. Peripheral and islet interleukin-17 pathway activation characterizes human autoimmune diabetes and promotes cytokine-mediated {beta}-cell death. Diabetes 2011, 60:2112-2119.
    • (2011) Diabetes , vol.60 , pp. 2112-2119
    • Arif, S.1    Moore, F.2    Marks, K.3    Bouckenooghe, T.4    Dayan, C.M.5    Planas, R.6    Vives-Pi, M.7    Powrie, J.8    Tree, T.9    Marchetti, P.10
  • 58
    • 70749093491 scopus 로고    scopus 로고
    • Gene expression profiles for the human pancreas and purified islets in type 1 diabetes: new findings at clinical onset and in long-standing diabetes
    • Planas R., Carrillo J., Sanchez A., de Villa M.C., Nunez F., Verdaguer J., James R.F., Pujol-Borrell R., Vives-Pi M. Gene expression profiles for the human pancreas and purified islets in type 1 diabetes: new findings at clinical onset and in long-standing diabetes. Clin Exp Immunol 2010, 159:23-44.
    • (2010) Clin Exp Immunol , vol.159 , pp. 23-44
    • Planas, R.1    Carrillo, J.2    Sanchez, A.3    de Villa, M.C.4    Nunez, F.5    Verdaguer, J.6    James, R.F.7    Pujol-Borrell, R.8    Vives-Pi, M.9
  • 59
    • 21244465464 scopus 로고    scopus 로고
    • Dynamic interaction between T cell-mediated beta-cell damage and beta-cell repair in the run up to autoimmune diabetes of the NOD mouse
    • Vukkadapu S.S., Belli J.M., Ishii K., Jegga A.G., Hutton J.J., Aronow B.J., Katz J.D. Dynamic interaction between T cell-mediated beta-cell damage and beta-cell repair in the run up to autoimmune diabetes of the NOD mouse. Physiol Genomics 2005, 21:201-211.
    • (2005) Physiol Genomics , vol.21 , pp. 201-211
    • Vukkadapu, S.S.1    Belli, J.M.2    Ishii, K.3    Jegga, A.G.4    Hutton, J.J.5    Aronow, B.J.6    Katz, J.D.7
  • 60
    • 12944319826 scopus 로고    scopus 로고
    • Homing of human autoreactive T cells into pancreatic tissue of NOD-scid mice
    • van Halteren A.G., Kardol M.J., Mulder A., Roep B.O. Homing of human autoreactive T cells into pancreatic tissue of NOD-scid mice. Diabetologia 2005, 48:75-82.
    • (2005) Diabetologia , vol.48 , pp. 75-82
    • van Halteren, A.G.1    Kardol, M.J.2    Mulder, A.3    Roep, B.O.4
  • 63
    • 85047690395 scopus 로고    scopus 로고
    • Autoreactive T cell responses show proinflammatory polarization in diabetes but a regulatory phenotype in health
    • Arif S., Tree T.I., Astill T.P., Tremble J.M., Bishop A.J., Dayan C.M., Roep B.O., Peakman M. Autoreactive T cell responses show proinflammatory polarization in diabetes but a regulatory phenotype in health. J Clin Invest 2004, 113:451-463.
    • (2004) J Clin Invest , vol.113 , pp. 451-463
    • Arif, S.1    Tree, T.I.2    Astill, T.P.3    Tremble, J.M.4    Bishop, A.J.5    Dayan, C.M.6    Roep, B.O.7    Peakman, M.8
  • 64
    • 77953223382 scopus 로고    scopus 로고
    • Naturally arising human CD4 T-cells that recognize islet autoantigens and secrete interleukin-10 regulate proinflammatory T-cell responses via linked suppression
    • Tree T.I., Lawson J., Edwards H., Skowera A., Arif S., Roep B.O., Peakman M. Naturally arising human CD4 T-cells that recognize islet autoantigens and secrete interleukin-10 regulate proinflammatory T-cell responses via linked suppression. Diabetes 2010, 59:1451-1460.
    • (2010) Diabetes , vol.59 , pp. 1451-1460
    • Tree, T.I.1    Lawson, J.2    Edwards, H.3    Skowera, A.4    Arif, S.5    Roep, B.O.6    Peakman, M.7
  • 65
    • 3042698353 scopus 로고    scopus 로고
    • HLA-DQ-regulated T-cell responses to islet cell autoantigens insulin and GAD65
    • Tree T.I., Duinkerken G., Willemen S., de Vries R.R., Roep B.O. HLA-DQ-regulated T-cell responses to islet cell autoantigens insulin and GAD65. Diabetes 2004, 53:1692-1699.
    • (2004) Diabetes , vol.53 , pp. 1692-1699
    • Tree, T.I.1    Duinkerken, G.2    Willemen, S.3    de Vries, R.R.4    Roep, B.O.5
  • 66
    • 33846550244 scopus 로고    scopus 로고
    • Identical beta cell-specific CD8(+) T cell clonotypes typically reside in both peripheral blood lymphocyte and pancreatic islets
    • Wong C.P., Stevens R., Long B., Li L., Wang Y., Wallet M.A., Goudy K.S., Frelinger J.A., Tisch R. Identical beta cell-specific CD8(+) T cell clonotypes typically reside in both peripheral blood lymphocyte and pancreatic islets. J Immunol 2007, 178:1388-1395.
    • (2007) J Immunol , vol.178 , pp. 1388-1395
    • Wong, C.P.1    Stevens, R.2    Long, B.3    Li, L.4    Wang, Y.5    Wallet, M.A.6    Goudy, K.S.7    Frelinger, J.A.8    Tisch, R.9
  • 68
    • 0028240799 scopus 로고
    • Selecting the T cell receptor repertoire
    • Bevan M.J., Hogquist K.A., Jameson S.C. Selecting the T cell receptor repertoire. Science 1994, 264:796-797.
    • (1994) Science , vol.264 , pp. 796-797
    • Bevan, M.J.1    Hogquist, K.A.2    Jameson, S.C.3
  • 70
    • 33747092627 scopus 로고    scopus 로고
    • T cells with low avidity for a tissue-restricted antigen routinely evade central and peripheral tolerance and cause autoimmunity
    • Zehn D., Bevan M.J. T cells with low avidity for a tissue-restricted antigen routinely evade central and peripheral tolerance and cause autoimmunity. Immunity 2006, 25:261-270.
    • (2006) Immunity , vol.25 , pp. 261-270
    • Zehn, D.1    Bevan, M.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.