Naturally arising human CD4 T-cells that recognize islet autoantigens and secrete interleukin-10 regulate proinflammatory T-cell responses via linked suppression

Diabetes

Volumn 59, Issue 6, 2010, Pages 1451-1460

  Tree, Timothy I M ^a,b   Lawson, Jennifer ^a   Edwards, Hannah ^a   Skowera, Ania ^a,b   Arif, Sefina ^a   Roep, Bart O ^c   Peakman, Mark ^a,b  

^a GUY S HOSPITAL   (United Kingdom)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c GUY'S AND ST THOMAS' NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIGEN; GRANZYME; INTERLEUKIN 10; PERFORIN;

ANTIGEN PRESENTING CELL; ARTICLE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOTOXICITY; EFFECTOR CELL; HUMAN; HUMAN EXPERIMENT; IMMUNE RESPONSE; INSULIN DEPENDENT DIABETES MELLITUS; NORMAL HUMAN; PANCREAS ISLET; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE;

AUTOANTIGENS; CD4-POSITIVE T-LYMPHOCYTES; CELL SURVIVAL; CYTOKINES; HUMANS; IMMUNOSUPPRESSION; INTERLEUKIN-10; ISLETS OF LANGERHANS; REFERENCE VALUES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; T-LYMPHOCYTES; T-LYMPHOCYTES, REGULATORY;

EID: 77953223382     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db09-0503     Document Type: Article

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