Deficiency of multidrug and toxin extrusion 1 enhances renal accumulation of paraquat and deteriorates kidney injury in mice

Molecular Pharmaceutics

Volumn 8, Issue 6, 2011, Pages 2476-2483

  Li, Qing ^a,b   Peng, Xiujuan ^a   Yang, Hyekyung ^a   Wang, Hongbing ^a   Shu, Yan ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF PHARMACY   (United States)

^b CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

genetic deficiency; multidrug and toxin extrusion 1 (MATE1 solute carrier 47A1); nephrotoxicity; Paraquat; pharmacokinetics

Indexed keywords

CARRIER PROTEIN; HERBICIDE; MULTIDRUG AND TOXIN EXTRUSION 1 PROTEIN; N ACETYL BETA GLUCOSAMINIDASE; PARAQUAT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD LEVEL; CELL TRANSPORT; CONTROLLED STUDY; GENE DISRUPTION; GENE FUNCTION; GENETIC TRANSFECTION; HISTOPATHOLOGY; KIDNEY INJURY; MOUSE; NEPHROTOXICITY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; TOXICOKINETICS; WILD TYPE;

ANIMALS; GENE DELETION; HERBICIDES; KIDNEY DISEASES; MICE; MICE, KNOCKOUT; ORGANIC CATION TRANSPORT PROTEINS; PARAQUAT;

EID: 82955240616     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp200395f     Document Type: Article

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