Functional characteristics of two human MATE transporters: Kinetics of cimetidine transport and profiles of inhibition by various compounds

Journal of Pharmacy and Pharmaceutical Sciences

Volumn 12, Issue 3, 2009, Pages 388-396

  Ohta, Kin ya ^a   Inoue, Katsuhisa ^a   Yasujima, Tomoya ^a   Ishimaru, Munenori ^b   Yuasa, Hiroaki ^a  

^a NAGOYA CITY UNIVERSITY   (Japan)

^b AICHI GAKUIN UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIPORTER; CIMETIDINE; COMPLEMENTARY DNA; MULTIDRUG AND TOXIN EXTRUSION PROTEIN 1; MULTIDRUG AND TOXIN EXTRUSION PROTEIN 2; RNA; TETRYLAMMONIUM; UNCLASSIFIED DRUG; ENZYME INHIBITOR; MATE1 PROTEIN, HUMAN; MATE1 PROTEIN, RAT; MATE2 K PROTEIN, HUMAN; MATE2-K PROTEIN, HUMAN; ORGANIC CATION TRANSPORTER;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING KINETICS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG PROTEIN BINDING; DRUG SCREENING; DRUG TRANSPORT; DRUG UPTAKE; HUMAN; HUMAN CELL; MICHAELIS CONSTANT; MOLECULAR RECOGNITION; PROTEIN FUNCTION; ANIMAL; COMPARATIVE STUDY; DRUG ANTAGONISM; GENETIC TRANSFECTION; GENETICS; ISOLATION AND PURIFICATION; KIDNEY; KINETICS; METABOLISM; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPECIES DIFFERENCE; TUMOR CELL LINE;

ANIMALS; ANTIPORTERS; CELL LINE, TUMOR; CIMETIDINE; DNA, COMPLEMENTARY; ENZYME INHIBITORS; HUMANS; KIDNEY; KINETICS; ORGANIC CATION TRANSPORT PROTEINS; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPECIES SPECIFICITY; TETRAETHYLAMMONIUM; TRANSFECTION;

EID: 77950355259     PISSN: None     EISSN: 14821826     Source Type: Journal    
DOI: 10.18433/j3r59x     Document Type: Article

References (11)

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