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Volumn 41, Issue 8, 2006, Pages 1213-1224

P-glycoprotein induction: an antidotal pathway for paraquat-induced lung toxicity

Author keywords

Dexamethasone; Free radicals; Lung toxicity; P glycoprotein; Paraquat

Indexed keywords

DEXAMETHASONE; GLYCOPROTEIN P; PARAQUAT; VERAPAMIL;

EID: 33749065926     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2006.06.012     Document Type: Article
Times cited : (86)

References (68)
  • 1
    • 0021751789 scopus 로고
    • A literature review of paraquat toxicity
    • Onyeama H.P., and Oehme F.W. A literature review of paraquat toxicity. Vet. Hum. Toxicol. 26 (1984) 494-502
    • (1984) Vet. Hum. Toxicol. , vol.26 , pp. 494-502
    • Onyeama, H.P.1    Oehme, F.W.2
  • 2
    • 0016319933 scopus 로고
    • Evidence for energy-dependent accumulation of paraquat into rat lung
    • Rose M.S., Smith L.L., and Wyatt I. Evidence for energy-dependent accumulation of paraquat into rat lung. Nature 252 (1974) 314-315
    • (1974) Nature , vol.252 , pp. 314-315
    • Rose, M.S.1    Smith, L.L.2    Wyatt, I.3
  • 4
    • 33746909463 scopus 로고    scopus 로고
    • Dinis-Oliveira, R. J.; Valle, M. J. d. J.; Bastos, M. L.; Carvalho, F.; Sánchez-Navarro, A. Kinetics of paraquat in the isolated rat lung: influence of sodium depletion. Xenobiotica (in press); 2006.
  • 5
    • 0024392071 scopus 로고
    • Synergistic interaction between NADPH-cytochrome P-450 reductase, paraquat and iron in the generation of active oxygen radicals
    • Clejan L., and Cederbaum A.I. Synergistic interaction between NADPH-cytochrome P-450 reductase, paraquat and iron in the generation of active oxygen radicals. Biochem. Pharmacol. 38 (1989) 1779-1786
    • (1989) Biochem. Pharmacol. , vol.38 , pp. 1779-1786
    • Clejan, L.1    Cederbaum, A.I.2
  • 6
    • 33751520926 scopus 로고    scopus 로고
    • Dinis-Oliveira, R. J.; Remião, F.; Duarte, J. A.; Sánchez-Navarro, A.; Bastos, M. L.; Carvalho, F. Paraquat exposure as an etiological factor of Parkinson's disease. Neurotoxicology (in press); 2006.
  • 7
    • 0027378686 scopus 로고
    • Mechanism of cytotoxicity of paraquat. I. NADH oxidation and paraquat radical formation via complex I
    • Fukushima T., Yamada K., Isobe A., Shiwaku K., and Yamane Y. Mechanism of cytotoxicity of paraquat. I. NADH oxidation and paraquat radical formation via complex I. Exp. Toxicol. Pathol. 45 (1993) 345-349
    • (1993) Exp. Toxicol. Pathol. , vol.45 , pp. 345-349
    • Fukushima, T.1    Yamada, K.2    Isobe, A.3    Shiwaku, K.4    Yamane, Y.5
  • 8
    • 0027521448 scopus 로고
    • Mechanism of cytotoxicity of paraquat. II. Organ specificity of paraquat-stimulated lipid peroxidation in the inner membrane of mitochondria
    • Yamada K., and Fukushima T. Mechanism of cytotoxicity of paraquat. II. Organ specificity of paraquat-stimulated lipid peroxidation in the inner membrane of mitochondria. Exp. Toxicol. Pathol. 45 (1993) 375-380
    • (1993) Exp. Toxicol. Pathol. , vol.45 , pp. 375-380
    • Yamada, K.1    Fukushima, T.2
  • 9
    • 0016153291 scopus 로고
    • Superoxide- and singlet oxygen-catalyzed lipid peroxidation as a possible mechanism for paraquat (methyl viologen) toxicity
    • Bus J.S., Aust S.D., and Gibson J.E. Superoxide- and singlet oxygen-catalyzed lipid peroxidation as a possible mechanism for paraquat (methyl viologen) toxicity. Biochem. Biophys. Res. Commun. 58 (1974) 749-755
    • (1974) Biochem. Biophys. Res. Commun. , vol.58 , pp. 749-755
    • Bus, J.S.1    Aust, S.D.2    Gibson, J.E.3
  • 10
    • 0025743946 scopus 로고
    • NADH-dependent generation of reactive oxygen species by microsomes in the presence of iron and redox cycling agents
    • Dicker E., and Cederbaum A.I. NADH-dependent generation of reactive oxygen species by microsomes in the presence of iron and redox cycling agents. Biochem. Pharmacol. 42 (1991) 529-535
    • (1991) Biochem. Pharmacol. , vol.42 , pp. 529-535
    • Dicker, E.1    Cederbaum, A.I.2
  • 11
    • 84973850974 scopus 로고
    • Pharmacological treatments of paraquat poisoning
    • Bateman D.N. Pharmacological treatments of paraquat poisoning. Hum. Toxicol. 6 (1987) 57-62
    • (1987) Hum. Toxicol. , vol.6 , pp. 57-62
    • Bateman, D.N.1
  • 13
    • 84973850955 scopus 로고
    • Treatment of paraquat poisoning in man: methods to prevent absorption
    • Meredith T.J., and Vale J.A. Treatment of paraquat poisoning in man: methods to prevent absorption. Hum. Toxicol. 6 (1987) 49-55
    • (1987) Hum. Toxicol. , vol.6 , pp. 49-55
    • Meredith, T.J.1    Vale, J.A.2
  • 14
    • 0022276132 scopus 로고
    • Transition metals potentiate paraquat toxicity
    • Kohen R., and Chevion M. Transition metals potentiate paraquat toxicity. Free Radic. Res. Commun. 1 (1985) 79-88
    • (1985) Free Radic. Res. Commun. , vol.1 , pp. 79-88
    • Kohen, R.1    Chevion, M.2
  • 15
    • 0037201949 scopus 로고    scopus 로고
    • Role of antioxidants in paraquat toxicity
    • Suntres Z.E. Role of antioxidants in paraquat toxicity. Toxicology 180 (2002) 65-77
    • (2002) Toxicology , vol.180 , pp. 65-77
    • Suntres, Z.E.1
  • 16
    • 0036851970 scopus 로고    scopus 로고
    • Combined methylprednisolone and dexamethasone therapy for paraquat poisoning
    • Chen G.H., Lin J.L., and Huang Y.K. Combined methylprednisolone and dexamethasone therapy for paraquat poisoning. Crit. Care Med. 30 (2002) 2584-2587
    • (2002) Crit. Care Med. , vol.30 , pp. 2584-2587
    • Chen, G.H.1    Lin, J.L.2    Huang, Y.K.3
  • 17
    • 0033010714 scopus 로고    scopus 로고
    • A prospective clinical trial of pulse therapy with glucocorticoid and cyclophosphamide in moderate to severe paraquat-poisoned patients
    • Lin J.L., Leu M.L., Liu Y.C., and Chen G.H. A prospective clinical trial of pulse therapy with glucocorticoid and cyclophosphamide in moderate to severe paraquat-poisoned patients. Am. J. Respir. Crit. Care Med. 159 (1999) 357-360
    • (1999) Am. J. Respir. Crit. Care Med. , vol.159 , pp. 357-360
    • Lin, J.L.1    Leu, M.L.2    Liu, Y.C.3    Chen, G.H.4
  • 18
    • 0036286847 scopus 로고    scopus 로고
    • Evidence for p-glycoprotein modification of insecticide toxicity in mosquitoes of the Culex pipiens complex
    • Buss D.S., McCaffery A.R., and Callaghan A. Evidence for p-glycoprotein modification of insecticide toxicity in mosquitoes of the Culex pipiens complex. Med. Vet. Entomol. 16 (2002) 218-222
    • (2002) Med. Vet. Entomol. , vol.16 , pp. 218-222
    • Buss, D.S.1    McCaffery, A.R.2    Callaghan, A.3
  • 19
    • 0025071180 scopus 로고
    • Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues
    • Cordon-Cardo C., O'Brien J., Boccia J., Casals D., Bertino J., and Melamed M. Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues. J. Histochem. Cytochem. 38 (1990) 1277-1287
    • (1990) J. Histochem. Cytochem. , vol.38 , pp. 1277-1287
    • Cordon-Cardo, C.1    O'Brien, J.2    Boccia, J.3    Casals, D.4    Bertino, J.5    Melamed, M.6
  • 20
    • 0027218689 scopus 로고
    • Biochemistry of multidrug resistance mediated by the multidrug transporter
    • Gottesman M.M., and Pastan I. Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu. Rev. Biochem. 62 (1993) 385-427
    • (1993) Annu. Rev. Biochem. , vol.62 , pp. 385-427
    • Gottesman, M.M.1    Pastan, I.2
  • 21
    • 0028234560 scopus 로고
    • Functional expression of P-glycoproteins in secretory vesicles
    • Ruetz S., and Gros P. Functional expression of P-glycoproteins in secretory vesicles. J. Biol. Chem. 269 (1994) 12277-12284
    • (1994) J. Biol. Chem. , vol.269 , pp. 12277-12284
    • Ruetz, S.1    Gros, P.2
  • 22
    • 0032933142 scopus 로고    scopus 로고
    • Dexamethasone modulation of multidrug transporters in normal tissues
    • Demeule M., Jodoin J., Beaulieu E., Brossard M., and Beliveau R. Dexamethasone modulation of multidrug transporters in normal tissues. FEBS Lett. 442 (1999) 208-214
    • (1999) FEBS Lett. , vol.442 , pp. 208-214
    • Demeule, M.1    Jodoin, J.2    Beaulieu, E.3    Brossard, M.4    Beliveau, R.5
  • 23
    • 0030966409 scopus 로고    scopus 로고
    • Kinetics of the multidrug transporter (P-glycoprotein) and its reversal
    • Stein W.D. Kinetics of the multidrug transporter (P-glycoprotein) and its reversal. Physiol. Rev. 77 (1997) 545-590
    • (1997) Physiol. Rev. , vol.77 , pp. 545-590
    • Stein, W.D.1
  • 24
    • 11144240987 scopus 로고    scopus 로고
    • The effect of verapamil on the pharmacokinetics of paclitaxel in rats
    • Choi J.S., and Li X. The effect of verapamil on the pharmacokinetics of paclitaxel in rats. Eur. J. Pharm. Sci. 24 (2005) 95-100
    • (2005) Eur. J. Pharm. Sci. , vol.24 , pp. 95-100
    • Choi, J.S.1    Li, X.2
  • 27
    • 0026780815 scopus 로고
    • A rapid, simultaneous determination of paraquat and diquat in serum and urine using second-derivative spectroscopy
    • Fuke C., Ameno K., Ameno S., Kiriu T., Shinohara T., Sogo K., and Ijiri I. A rapid, simultaneous determination of paraquat and diquat in serum and urine using second-derivative spectroscopy. J. Anal. Toxicol. 16 (1992) 214-216
    • (1992) J. Anal. Toxicol. , vol.16 , pp. 214-216
    • Fuke, C.1    Ameno, K.2    Ameno, S.3    Kiriu, T.4    Shinohara, T.5    Sogo, K.6    Ijiri, I.7
  • 28
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227 (1970) 680-685
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 30
    • 0038693217 scopus 로고    scopus 로고
    • Methylprednisolone effects on oxygenation and histology in a rat model of acute lung injury
    • Chen C.M., Wang L.F., Su B., and Hsu H.H. Methylprednisolone effects on oxygenation and histology in a rat model of acute lung injury. Pulm. Pharmacol. Ther. 16 (2003) 215-220
    • (2003) Pulm. Pharmacol. Ther. , vol.16 , pp. 215-220
    • Chen, C.M.1    Wang, L.F.2    Su, B.3    Hsu, H.H.4
  • 34
    • 0017872475 scopus 로고
    • Microsomal lipid peroxidation
    • Buege J.A., and Aust S.D. Microsomal lipid peroxidation. Methods Enzymol. 52 (1978) 302-310
    • (1978) Methods Enzymol. , vol.52 , pp. 302-310
    • Buege, J.A.1    Aust, S.D.2
  • 35
    • 0028291974 scopus 로고
    • Carbonyl assay for determination of oxidatively modified proteins
    • Levine R.L., Williams J.A., Stadtman E.R., and Shacter E. Carbonyl assay for determination of oxidatively modified proteins. Methods Enzymol. 233 (1994) 346-357
    • (1994) Methods Enzymol. , vol.233 , pp. 346-357
    • Levine, R.L.1    Williams, J.A.2    Stadtman, E.R.3    Shacter, E.4
  • 36
    • 0020426962 scopus 로고
    • Quantitative determination of myeloperoxidase using tetramethylbenzidine as substrate
    • Andrews P.C., and Krinsky N.I. Quantitative determination of myeloperoxidase using tetramethylbenzidine as substrate. Anal. Biochem. 127 (1982) 346-350
    • (1982) Anal. Biochem. , vol.127 , pp. 346-350
    • Andrews, P.C.1    Krinsky, N.I.2
  • 37
    • 0020550892 scopus 로고
    • Assay method for myeloperoxidase in human polymorphonuclear leukocytes
    • Suzuki K., Ota H., Sasagawa S., Sakatani T., and Fujikura T. Assay method for myeloperoxidase in human polymorphonuclear leukocytes. Anal. Biochem. 132 (1983) 345-352
    • (1983) Anal. Biochem. , vol.132 , pp. 345-352
    • Suzuki, K.1    Ota, H.2    Sasagawa, S.3    Sakatani, T.4    Fujikura, T.5
  • 38
    • 0027946067 scopus 로고
    • A microtiter plate assay for total glutathione and glutathione disulfide contents in cultured/isolated cells: performance study of a new miniaturized protocol
    • Vandeputte C., Guizon I., Genestie-Denis I., Vannier B., and Lorenzon G. A microtiter plate assay for total glutathione and glutathione disulfide contents in cultured/isolated cells: performance study of a new miniaturized protocol. Cell Biol. Toxicol. 10 (1994) 415-421
    • (1994) Cell Biol. Toxicol. , vol.10 , pp. 415-421
    • Vandeputte, C.1    Guizon, I.2    Genestie-Denis, I.3    Vannier, B.4    Lorenzon, G.5
  • 39
    • 0021288878 scopus 로고
    • Superoxide dismutase assays
    • Flohe L., and Otting F. Superoxide dismutase assays. Methods Enzymol. 105 (1984) 93-104
    • (1984) Methods Enzymol. , vol.105 , pp. 93-104
    • Flohe, L.1    Otting, F.2
  • 41
    • 0030925683 scopus 로고    scopus 로고
    • Steroid receptor interactions with heat shock protein and immunophilin chaperones
    • Pratt W.B., and Toft D.O. Steroid receptor interactions with heat shock protein and immunophilin chaperones. Endocr. Rev. 18 (1997) 306-360
    • (1997) Endocr. Rev. , vol.18 , pp. 306-360
    • Pratt, W.B.1    Toft, D.O.2
  • 43
    • 0027296765 scopus 로고
    • Regulation by dexamethasone of P-glycoprotein expression in cultured rat hepatocytes
    • Fardel O., Lecureur V., and Guillouzo A. Regulation by dexamethasone of P-glycoprotein expression in cultured rat hepatocytes. FEBS Lett. 327 (1993) 189-193
    • (1993) FEBS Lett. , vol.327 , pp. 189-193
    • Fardel, O.1    Lecureur, V.2    Guillouzo, A.3
  • 44
    • 0022972654 scopus 로고
    • Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells
    • Chen C.J., Chin J.E., Ueda K., Clark D.P., Pastan I., Gottesman M.M., and Roninson I.B. Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells. Cell 47 (1986) 381-389
    • (1986) Cell , vol.47 , pp. 381-389
    • Chen, C.J.1    Chin, J.E.2    Ueda, K.3    Clark, D.P.4    Pastan, I.5    Gottesman, M.M.6    Roninson, I.B.7
  • 45
    • 0024544045 scopus 로고
    • The three mouse multidrug resistance (mdr) genes are expressed in a tissue-specific manner in normal mouse tissue
    • Croop J.M., Raymond M., Haber D., Devault A., Arceci R.J., Gros P., and Housman D.E. The three mouse multidrug resistance (mdr) genes are expressed in a tissue-specific manner in normal mouse tissue. Mol. Cell. Biol. 9 (1989) 1346-1350
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 1346-1350
    • Croop, J.M.1    Raymond, M.2    Haber, D.3    Devault, A.4    Arceci, R.J.5    Gros, P.6    Housman, D.E.7
  • 47
    • 0032519643 scopus 로고    scopus 로고
    • Modulation of P-glycoprotein expression by cytochrome P450 3A inducers in male and female rat livers
    • Salphati L., and Benet L.Z. Modulation of P-glycoprotein expression by cytochrome P450 3A inducers in male and female rat livers. Biochem. Pharmacol. 55 (1998) 387-395
    • (1998) Biochem. Pharmacol. , vol.55 , pp. 387-395
    • Salphati, L.1    Benet, L.Z.2
  • 49
    • 0345411548 scopus 로고    scopus 로고
    • Pharmacokinetics of high-dose oral and intravenous dexamethasone
    • Toth G.G., Kloosterman C., Uges D.R., and Jonkman M.F. Pharmacokinetics of high-dose oral and intravenous dexamethasone. Ther. Drug. Monit. 21 (1999) 532-535
    • (1999) Ther. Drug. Monit. , vol.21 , pp. 532-535
    • Toth, G.G.1    Kloosterman, C.2    Uges, D.R.3    Jonkman, M.F.4
  • 50
    • 0035813008 scopus 로고    scopus 로고
    • Regulation of biliary drug efflux pump expression by hormones and xenobiotics
    • Fardel O., Payen L., Courtois A., Vernhet L., and Lecureur V. Regulation of biliary drug efflux pump expression by hormones and xenobiotics. Toxicology 167 (2001) 37-46
    • (2001) Toxicology , vol.167 , pp. 37-46
    • Fardel, O.1    Payen, L.2    Courtois, A.3    Vernhet, L.4    Lecureur, V.5
  • 51
    • 0036865203 scopus 로고    scopus 로고
    • Drug membrane transporters in the liver: regulation of their expression and activity
    • Fardel O., Payen L., Sparfel L., Vernhet L., and Lecureur V. Drug membrane transporters in the liver: regulation of their expression and activity. Ann. Pharm. Fr. 60 (2002) 380-385
    • (2002) Ann. Pharm. Fr. , vol.60 , pp. 380-385
    • Fardel, O.1    Payen, L.2    Sparfel, L.3    Vernhet, L.4    Lecureur, V.5
  • 52
    • 0015723997 scopus 로고
    • Biliary excretion of some diquaternary ammonium cations in the rat, guinea pig and rabbit
    • Hughes R.D., Millburn P., and Williams R.T. Biliary excretion of some diquaternary ammonium cations in the rat, guinea pig and rabbit. Biochem. J. 136 (1973) 979-984
    • (1973) Biochem. J. , vol.136 , pp. 979-984
    • Hughes, R.D.1    Millburn, P.2    Williams, R.T.3
  • 53
    • 0029800447 scopus 로고    scopus 로고
    • Active secretion of drugs from the small intestinal epithelium in rats by P-glycoprotein functioning as an absorption barrier
    • Terao T., Hisanaga E., Sai Y., Tamai I., and Tsuji A. Active secretion of drugs from the small intestinal epithelium in rats by P-glycoprotein functioning as an absorption barrier. J. Pharm. Pharmacol. 48 (1996) 1083-1089
    • (1996) J. Pharm. Pharmacol. , vol.48 , pp. 1083-1089
    • Terao, T.1    Hisanaga, E.2    Sai, Y.3    Tamai, I.4    Tsuji, A.5
  • 54
    • 0030598380 scopus 로고    scopus 로고
    • Alleviation of paraquat-induced lung injury by pretreatment with bifunctional liposomes containing alpha-tocopherol and glutathione
    • Suntres Z.E., and Shek P.N. Alleviation of paraquat-induced lung injury by pretreatment with bifunctional liposomes containing alpha-tocopherol and glutathione. Biochem. Pharmacol. 52 (1996) 1515-1520
    • (1996) Biochem. Pharmacol. , vol.52 , pp. 1515-1520
    • Suntres, Z.E.1    Shek, P.N.2
  • 55
    • 10244262629 scopus 로고
    • N-acetylcysteine pretreatment attenuates paraquat-induced lung leak in rats
    • Hybertson B.M., Lampey A.S., Clarke J.H., Koh Y., and Repine J.E. N-acetylcysteine pretreatment attenuates paraquat-induced lung leak in rats. Redox Rep. 1 (1995) 337-342
    • (1995) Redox Rep. , vol.1 , pp. 337-342
    • Hybertson, B.M.1    Lampey, A.S.2    Clarke, J.H.3    Koh, Y.4    Repine, J.E.5
  • 56
    • 0030735166 scopus 로고    scopus 로고
    • Tumour necrosis factor-alpha expression and cell recruitment in Sephadex particle-induced lung inflammation: effects of dexamethasone and cyclosporin A
    • Williams C.M., Smith L., Flanagan B.F., Clegg L.S., and Coleman J.W. Tumour necrosis factor-alpha expression and cell recruitment in Sephadex particle-induced lung inflammation: effects of dexamethasone and cyclosporin A. Br. J. Pharmacol. 122 (1997) 1127-1134
    • (1997) Br. J. Pharmacol. , vol.122 , pp. 1127-1134
    • Williams, C.M.1    Smith, L.2    Flanagan, B.F.3    Clegg, L.S.4    Coleman, J.W.5
  • 57
    • 0032911805 scopus 로고    scopus 로고
    • The alveolar space is the site of intense inflammatory and profibrotic reactions in the early phase of acute respiratory distress syndrome
    • Pugin J., Verghese G., Widmer M.C., and Matthay M.A. The alveolar space is the site of intense inflammatory and profibrotic reactions in the early phase of acute respiratory distress syndrome. Crit. Care Med. 27 (1999) 304-312
    • (1999) Crit. Care Med. , vol.27 , pp. 304-312
    • Pugin, J.1    Verghese, G.2    Widmer, M.C.3    Matthay, M.A.4
  • 58
    • 0035173303 scopus 로고    scopus 로고
    • Surfactant and corticosteroid effects on lung function in a rat model of acute lung injury
    • Chen C.M., Fang C.L., and Chang C.H. Surfactant and corticosteroid effects on lung function in a rat model of acute lung injury. Crit. Care Med. 29 (2001) 2169-2175
    • (2001) Crit. Care Med. , vol.29 , pp. 2169-2175
    • Chen, C.M.1    Fang, C.L.2    Chang, C.H.3
  • 60
    • 0028604523 scopus 로고
    • Mechanism of cytotoxicity of paraquat: III. The effects of acute paraquat exposure on the electron transport system in rat mitochondria
    • Fukushima T., Yamada K., Hojo N., Isobe A., Shiwaku K., and Yamane Y. Mechanism of cytotoxicity of paraquat: III. The effects of acute paraquat exposure on the electron transport system in rat mitochondria. Exp. Toxicol. Pathol. 46 (1994) 437-441
    • (1994) Exp. Toxicol. Pathol. , vol.46 , pp. 437-441
    • Fukushima, T.1    Yamada, K.2    Hojo, N.3    Isobe, A.4    Shiwaku, K.5    Yamane, Y.6
  • 62
    • 0018976226 scopus 로고
    • Liver necrosis and lipid peroxidation in the rat as result of paraquat and diquat administration: effect of selenium deficiency
    • Burk R.F., Lawrence R.A., and Lane J.M. Liver necrosis and lipid peroxidation in the rat as result of paraquat and diquat administration: effect of selenium deficiency. J. Clin. Invest. 65 (1980) 1024-1031
    • (1980) J. Clin. Invest. , vol.65 , pp. 1024-1031
    • Burk, R.F.1    Lawrence, R.A.2    Lane, J.M.3
  • 63
    • 0030988742 scopus 로고    scopus 로고
    • Biochemistry and pathology of radical-mediated protein oxidation
    • Dean R.T., Fu S., Stocker R., and Davies M.J. Biochemistry and pathology of radical-mediated protein oxidation. Biochem. J. 324 (1997) 1-18
    • (1997) Biochem. J. , vol.324 , pp. 1-18
    • Dean, R.T.1    Fu, S.2    Stocker, R.3    Davies, M.J.4
  • 64
    • 0021359583 scopus 로고
    • Gamma-glutamylcysteine synthetase: interactions of an essential sulfhydryl group
    • Seelig G.F., and Meister A. Gamma-glutamylcysteine synthetase: interactions of an essential sulfhydryl group. J. Biol. Chem. 259 (1984) 3534-3538
    • (1984) J. Biol. Chem. , vol.259 , pp. 3534-3538
    • Seelig, G.F.1    Meister, A.2
  • 65
    • 0023263523 scopus 로고
    • Normal alveolar epithelial lining fluid contains high levels of glutathione
    • Cantin A.M., North S.L., Hubbard R.C., and Crystal R.G. Normal alveolar epithelial lining fluid contains high levels of glutathione. J. Appl. Physiol. 63 (1987) 152-157
    • (1987) J. Appl. Physiol. , vol.63 , pp. 152-157
    • Cantin, A.M.1    North, S.L.2    Hubbard, R.C.3    Crystal, R.G.4
  • 66
    • 0028361794 scopus 로고
    • An investigation of the role of glutathione in increased epithelial permeability induced by cigarette smoke in vivo and in vitro
    • Li X.Y., Donaldson K., Rahman I., and MacNee W. An investigation of the role of glutathione in increased epithelial permeability induced by cigarette smoke in vivo and in vitro. Am. J. Respir. Crit. Care Med. 149 (1994) 1518-1525
    • (1994) Am. J. Respir. Crit. Care Med. , vol.149 , pp. 1518-1525
    • Li, X.Y.1    Donaldson, K.2    Rahman, I.3    MacNee, W.4
  • 67
    • 0025259693 scopus 로고
    • Lipid peroxidation and antioxidant systems in the liver injury produced by glutathione depleting agents
    • Maellaro E., Casini A.F., Bello B.D., and Comporti M. Lipid peroxidation and antioxidant systems in the liver injury produced by glutathione depleting agents. Biochem. Pharmacol. 39 (1990) 1513-1521
    • (1990) Biochem. Pharmacol. , vol.39 , pp. 1513-1521
    • Maellaro, E.1    Casini, A.F.2    Bello, B.D.3    Comporti, M.4
  • 68
    • 0019951360 scopus 로고
    • Relevance of NADPH depletion and mixed disulphide formation in rat lung to the mechanism of cell damage following paraquat administration
    • Keeling P.L., and Smith L.L. Relevance of NADPH depletion and mixed disulphide formation in rat lung to the mechanism of cell damage following paraquat administration. Biochem. Pharmacol. 31 (1982) 3243-3249
    • (1982) Biochem. Pharmacol. , vol.31 , pp. 3243-3249
    • Keeling, P.L.1    Smith, L.L.2


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