Disruption of endocrine function in in vitro H295R cell-based and in in vivo assay in zebrafish by 2,4-dichlorophenol

Aquatic Toxicology

Volumn 106-107, Issue , 2012, Pages 173-181

  Ma, Yanbo ^a,b   Han, Jian ^a   Guo, Yongyong ^a   Lam, Paul K S ^c   Wu, Rudolf S S ^d   Giesy, John P ^c,d,e,f   Zhang, Xiaowei ^g   Zhou, Bingsheng ^a  

^a INSTITUTE OF HYDROBIOLOGY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c CITY UNIVERSITY OF HONG KONG   (Hong Kong)

^d UNIVERSITY OF HONG KONG   (Hong Kong)

^e UNIVERSITY OF SASKATCHEWAN   (Canada)

^f KING SAUD UNIVERSITY   (Saudi Arabia)

^g NANJING UNIVERSITY   (China)

Author keywords

H295R; Hormones; HPG axis; In vitro; In vivo; Zebrafish

Indexed keywords

2,4 DICHLOROPHENOL; 3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; AROMATASE; CYTOCHROME P450; CYTOCHROME P450 11A; CYTOCHROME P450 17; CYTOCHROME P450 19A; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; MESSENGER RNA; PROSTAGLANDIN SYNTHASE; STEROIDOGENIC ACUTE REGULATORY PROTEIN; TESTOSTERONE; TESTOSTERONE 17BETA DEHYDROGENASE; UNCLASSIFIED DRUG; VITELLOGENIN;

CELL ORGANELLE; ENDOCRINE DISRUPTOR; FISH; HORMONE; PHENOL; POLLUTION EFFECT; POLLUTION EXPOSURE; RNA; TESTOSTERONE;

ADRENAL CORTEX CELL; ARTICLE; CARCINOMA CELL; CELL STRAIN; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; ENDOCRINE DISEASE; FEMALE; GENE EXPRESSION; GENETIC TRANSCRIPTION; HATCHING; HORMONE BLOOD LEVEL; HYPOTHALAMUS HYPOPHYSIS GONAD SYSTEM; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REPRODUCTION; SPAWNING; STEROIDOGENESIS; TRANSCRIPTION REGULATION; UPREGULATION; ZEBRA FISH;

DANIO RERIO;

EID: 82955189216     PISSN: 0166445X     EISSN: 18791514     Source Type: Journal    
DOI: 10.1016/j.aquatox.2011.11.006     Document Type: Article

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