Effects of sulfathiazole, oxytetracycline and chlortetracycline on steroidogenesis in the human adrenocarcinoma (H295R) cell line and freshwater fish Oryzias latipes

Journal of Hazardous Materials

Volumn 182, Issue 1-3, 2010, Pages 494-502

  Ji, Kyunghee ^a   Choi, Kyungho ^a   Lee, Sangwoo ^a   Park, Saerom ^b   Khim, Jong Seong ^b   Jo, Eun Hye ^c   Choi, Kyunghee ^c   Zhang, Xiaowei ^d   Giesy, John P ^d,e,f,g,h  

^a Seoul National University   (South Korea)

^b Korea University   (South Korea)

^c National Institute of Environmental Research   (South Korea)

^d NANJING UNIVERSITY   (China)

^e UNIVERSITY OF SASKATCHEWAN   (Canada)

^f MICHIGAN STATE UNIVERSITY   (United States)

^g CITY UNIVERSITY OF HONG KONG   (Hong Kong)

^h XIAMEN UNIVERSITY   (China)

Author keywords

Antibiotic; Aromatase; Endocrine disruption; Pharmaceutical; Steroidogenesis

Indexed keywords

CELL CULTURE; DRUG PRODUCTS; ECOSYSTEMS; ENDOCRINE DISRUPTERS; ENZYME ACTIVITY; FISH; GENE EXPRESSION;

AROMATASE; ECOSYSTEM HEALTH; ENDOCRINE DISRUPTION; ENDOCRINE SYSTEMS; FRESHWATER FISHES; OXYTETRACYCLINES (OTC); POTENT COMPOUNDS; STEROIDOGENESIS;

ANTIBIOTICS;

3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; AROMATASE; CHLORTETRACYCLINE; CYTOCHROME P450 17; DICLOFENAC; ERYTHROMYCIN; ESTRADIOL; OXYTETRACYCLINE; SULFADIMIDINE; SULFATHIAZOLE; TESTOSTERONE;

ANTIBIOTICS; CHEMICAL POLLUTANT; CYTOLOGY; ECOSYSTEM HEALTH; ENDOCRINE DISRUPTOR; ENDOCRINE SYSTEM; ENZYME ACTIVITY; FITNESS; GROWTH RATE; HEALTH RISK; PUBLIC HEALTH; REPRODUCTIVE STRATEGY; TELEOST;

ANIMAL EXPERIMENT; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG EXPOSURE; ENZYME ACTIVITY; GENE EXPRESSION; HORMONE SYNTHESIS; HUMAN; HUMAN CELL; MALE; NONHUMAN; ORYZIAS; STEROIDOGENESIS; UPREGULATION; XENOBIOTIC METABOLISM;

KOREA;

ORYZIAS LATIPES; ORYZIINAE;

EID: 77955583292     PISSN: 03043894     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhazmat.2010.06.059     Document Type: Article

References (32)

1. Kemper N. Veterinary antibiotics in the aquatic and terrestrial environment. Ecol. Ind. 2008, 8:1-13.
2. Kolpin D.W., Furlong E.T., Meyer M.T., Thurman E.M., Zaugg S.D., Barber L.B., Buxton H.T. Pharmaceuticals, hormones, and other organic wastewater contaminants in U.S. strams, 1999-2000: a national reconnaissance. Environ. Sci. Technol. 2002, 36:1202-1211.
3. Brun G.L., Bernier M., Losier R., Doe K., Jackman P., Lee H.B. Pharmaceutically active compounds in Atlantic Canadian sewage treatment plant effluents and receiving waters and potential for environmental effects as measured by acute and chronic aquatic toxicity. Environ. Toxicol. Chem. 2006, 25:2163-2176.
4. Chang H., Hu J., Asami M., Kunikane S. Simultaneous analysis of 16 sulfonamide and trimethoprim antibiotics in environmental waters by liquid chromatography-electrospray tandem mass spectrometry. J. Chromatogr. A 2008, 1190:390-393.
5. Choi K., Kim Y.H., Park J., Park C.K., Kim M.Y., Kim H.S., Kim P.G. Seasonal variations of several pharmaceutical residues in surface water and sewage treatment plants of Han River, Korea. Sci. Total Environ. 2008, 405:120-128.
6. Duong H.A., Pham N.H., Nguyen H.T., Hoang T.T., Pham H.V., Pham V.C., Berg M., Giger W., Alder A.C. Occurrence, fate and antibiotic resistance of fluoroquinolone antibacterials in hospital wastewaters in Hanoi, Vietnam. Chemosphere 2008, 72:968-973.
7. Hernando M.D., Mezcua M., Fernandez-Alba A.R., Barcelo D. Environmental risk assessment of pharmaceutical residues in wastewater effluents, surface waters and sediments. Talanta 2006, 69:334-342.
8. Kümmerer K. Antibiotics in the aquatic environment-a review-part I. Chemosphere 2009, 75:417-434.
9. Lishman L., Smyth S.A., Sarafin K., Kleywegt S., Toito J., Peart T., Lee B., Servos M., Beland M., Seto P. Occurrence and reductions of pharmaceuticals and person care products and estrogens by municipal wastewater treatment plants in Ontario, Canada. Sci. Total Environ. 2006, 367:544-558.
10. Roberts P.H., Thomas K.V. The occurrence of selected pharmaceuticals in wastewater effluent and surface waters of the lower Tyne catchment. Sci. Total Environ. 2006, 356:143-153.
11. Fent K., Weston A.A., Caminada D. Ecotoxicology of human pharmaceuticals. Aquat. Toxicol. 2006, 76:122-159.
12. Fent K., Escher C., Caminada D. Estrogenic activity of pharmaceuticals and pharmaceutical mixtures in a yeast reporter gene system. Reprod. Toxicol. 2006, 22:175-185.
13. Isidori M., Bellotta M., Cangiano M., Parrella A. Estrogenic activity of pharmaceuticals in the aquatic environment. Environ. Int. 2009, 35:826-829.
14. Gracia T., Hilscherova K., Jones P.D., Newsted J.L., Higley E.B., Zhang X., Hecker M., Murphy M.B., Yu R.M., Lam P.K., Wu R.S., Giesy J.P. Modulation of steroidogenic gene expression and hormone production of H295R cells by pharmaceuticals and other environmentally active compounds. Toxicol. Appl. Pharmacol. 2007, 225:142-153.
15. Kang H.J., Kim H.S., Choi K.H., Kim K.T., Kim P.G. Several human pharmaceutical residues in aquatic environment may result in endocrine disruption in Japanese medaka (Oryzias latipes). Kor. J. Environ. Health 2005, 31:227-233.
16. Kim P.G. Chlortetracycline caused vitellogenin induction at male Japanese medaka (Oryzias latipes). Kor. J. Environ. Health 2007, 33:513-516.
17. Hilscherova K., Jones P.D., Gracia T., Newsted J.L., Zhang X.W., Sanderson J.T., Yu R.M., Wu R.S., Giesy J.P. Assessment of the effects of chemicals on the expression of ten steroidogenic genes in the H295R cell line using real-time PCR. Toxicol. Sci. 2004, 81:78-89.
18. Zhang X.W., Yu R.M.K., Jones P.D., Lam G.K.W., Newsted J.L., Gracia T., Hecker M., Hilscherova K., Sanderson T., Wu R.S., Giesy J.P. Quantitative RT-PCR methods for evaluating toxicant-induced effects on steroidogenesis using the H295R cell line. Environ. Sci. Technol. 2005, 39:2777-2785.
19. National Institute of Environmental Research, Development of Analytical Method and Study of Exposure of Pharmaceuticals and Personal Care Products in Environment (I), Ministry of Environment, Korea, 2006.
20. National Institute of Environmental Research, Development of Analytical Method and Study of Exposure of Pharmaceuticals and Personal Care Products in Environment (II), Ministry of Environment, Korea, 2007.
21. Hecker M., Newsted J.L., Murphy M.B., Higley E.B., Jones P.D., Wu R.S., Giesy J.P. Human adrenocarcinoma (H295R) cells for rapid in vitro determination of effects on steroidogenesis: hormone production. Toxicol. Appl. Pharmacol. 2006, 217:114-124.
22. He Y., Murphy M.B., Yu R.M., Lam M.H., Hecker M., Giesy J.P., Wu R.S., Lam P.K. Effects of 20 PBDE metabolites on steroidogenesis in the H295R cell line. Toxicol. Lett. 2008, 176:230-238.
23. Han S.Y., Choi K., Kim J.K., Ji K.H., Kim S.M., Ahn B.W., Yun J.H., Choi K.H., Khim J.S., Zhang X., Giesy J.P. Endocrine disruption and consequences of chronic exposure to ibuprofen in Japanese medaka (Oryzias latipes) and freshwater cladocerans Daphnia magna and Moina macrocopa. Aquat. Toxicol. 2010, 98:256-264.
24. Cobb V.J., Williams B.C., Mason J.I., Walker S.W. Forskolin treatment directs steroid production towards the androgen pathway in the NCI-H295R adrenocortical tumour cell line. Endocr. Res. 1996, 22:545-550.
25. Kumar V., Chakraborty A., Kural M.R., Roy P. Alteration of testicular steroidogenesis and histopathology of reproductive system in male rats treated with triclosan. Reprod. Toxicol. 2008, 27:177-185.
26. Kang H.J., Choi K.H., Kim M.Y., Kim P.G. Endocrine disruption induced by some sulfa drugs and tetracyclines on Oryzias latipes. Kor. J. Environ. Health 2005, 32:227-234.
27. Park S., Choi K. Hazard assessment of commonly used agricultural antibiotics on aquatic ecosystems. Ecotoxicology 2008, 17:526-538.
28. Watkinson A.J., Murby E.J., Kolpin D.W., Costanzo S.D. The occurrence of antibiotics in an urban watershed: from wastewater to drinking water. Sci. Total Environ. 2009, 407:2711-2723.
29. National Institute of Environmental Research, Development of Analytical Method and Study of Exposure of Pharmaceuticals and Personal Care Products in Environment (III), Ministry of Environment, Korea, 2008.
30. Snyder S.A., Villeneuve D.L., Snyder E.M., Giesy J.P. Identification and quantification of estrogen receptor agonists in wastewater effluents. Environ. Sci. Technol. 2001, 35:3620-3625.
31. Silva E., Rajapakse N., Kortenkamp A. Something from " nothing" -eight weak estrogenic chemicals combined at concentrations below NOECs produce significant mixture effects. Environ. Sci. Technol. 2002, 36:1751-1756.
32. Hasselberg L., Westerberg S., Wassmur B., Celander M.C., Ketoconazole an antifungal imidazole, increases the sensitivity of rainbow trout to 17α-ethylnylestradiol exposure. Aquat. Toxicol. 2008, 86:256-264.