Real-time PCR array to study effects of chemicals on the Hypothalamic-Pituitary-Gonadal axis of the Japanese medaka

Aquatic Toxicology

Volumn 88, Issue 3, 2008, Pages 173-182

  Zhang, Xiaowei ^a   Hecker, Markus ^a,b,c   Park, June Woo ^a   Tompsett, Amber R ^a   Newsted, John ^a,b   Nakayama, Kei ^d   Jones, Paul D ^a,c   Au, Doris ^e   Kong, Richard ^e   Wu, Rudolf S S ^e   Giesy, John P ^a,c,e  

^a MICHIGAN STATE UNIVERSITY   (United States)

^b ENTRIX INC   (United States)

^c UNIVERSITY OF SASKATCHEWAN   (Canada)

^d EHIME UNIVERSITY   (Japan)

^e CITY UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Endocrine; Expression profile; Fecundity; Fish; Steroidogenesis

Indexed keywords

ETHINYLESTRADIOL; MESSENGER RNA; TRENBOLONE;

CHEMICAL CUE; CHEMICAL POLLUTANT; ENDOCRINE DISRUPTOR; ESTROGENIC COMPOUND; FECUNDITY; GENE EXPRESSION; POLLUTION EXPOSURE; POLYMERASE CHAIN REACTION; SEXUAL BEHAVIOR; TELEOST;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN; CONTROLLED STUDY; CYP17 GENE; CYP19A GENE; DOWN REGULATION; FEMALE; GENE; GENE EXPRESSION; GNRH R1 GENE; GNRH R2 GENE; GONAD; HYPOTHALAMUS HYPOPHYSIS GONAD SYSTEM; LIVER; MALE; MICROARRAY ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; ORYZIAS; OVARY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SEXUAL BEHAVIOR; UPREGULATION;

ANIMALS; AROMATASE; ETHINYL ESTRADIOL; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; MALE; ORYZIAS; PITUITARY-ADRENAL SYSTEM; RECEPTORS, ANDROGEN; RECEPTORS, LHRH; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; STATISTICS, NONPARAMETRIC; STEROID 17-ALPHA-HYDROXYLASE; TRENBOLONE;

ORYZIAS LATIPES; ORYZIINAE;

EID: 46749127694     PISSN: 0166445X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.aquatox.2008.04.009     Document Type: Article

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