-
1
-
-
32944462834
-
Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3
-
K anneganti TD, Ozören N, Body-Malapel M, et al. Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3. Nature 2006;440:233-6.
-
(2006)
Nature
, vol.440
, pp. 233-236
-
-
Kanneganti, T.D.1
Ozören, N.2
Body-Malapel, M.3
-
2
-
-
32944470765
-
Cryopyrin activates the inflammasome in response to toxins and ATP
-
DOI 10.1038/nature04515, PII N04515
-
Mariathasan S, Weiss DS, Newton K, et al. Cryopyrin activates the inflammasome in response to toxins and ATP. Nature 2006;440:228-32. (Pubitemid 43372102)
-
(2006)
Nature
, vol.440
, Issue.7081
, pp. 228-232
-
-
Mariathasan, S.1
Weiss, D.S.2
Newton, K.3
McBride, J.4
O'Rourke, K.5
Roose-Girma, M.6
Lee, W.P.7
Weinrauch, Y.8
Monack, D.M.9
Dixit, V.M.10
-
3
-
-
32944468985
-
Gout-associated uric acid crystals activate the NALP3 inflammasome
-
DOI 10.1038/nature04516, PII N04516
-
Martinon F, Pétrilli V, Mayor A, et al. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature 2006;440:237-41. (Pubitemid 43372104)
-
(2006)
Nature
, vol.440
, Issue.7081
, pp. 237-241
-
-
Martinon, F.1
Petrilli, V.2
Mayor, A.3
Tardivel, A.4
Tschopp, J.5
-
4
-
-
33644985564
-
Critical role for NALP3/CIAS1/ Cryopyrin in innate and adaptive immunity through its regulation of caspase-1
-
Sutterwala FS, Ogura Y, Szczepanik M, et al. Critical role for NALP3/CIAS1/ Cryopyrin in innate and adaptive immunity through its regulation of caspase-1. Immunity 2006;24:317-27.
-
(2006)
Immunity
, vol.24
, pp. 317-327
-
-
Sutterwala, F.S.1
Ogura, Y.2
Szczepanik, M.3
-
5
-
-
1642285783
-
NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder
-
DOI 10.1016/S1074-7613(04)00046-9, PII S1074761304000469
-
Agostini L, Martinon F, Burns K, et al. NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder. Immunity 2004;20:319-25. (Pubitemid 38388233)
-
(2004)
Immunity
, vol.20
, Issue.3
, pp. 319-325
-
-
Agostini, L.1
Martinon, F.2
Burns, K.3
McDermott, M.F.4
Hawkins, P.N.5
Tschopp, J.6
-
6
-
-
0036899758
-
De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID): A new member of the expanding family of pyrin-associated autoinflammatory diseases
-
DOI 10.1002/art.10688
-
Aksentijevich I, Nowak M, Mallah M, et al. De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID): a new member of the expanding family of pyrin-associated autoinflammatory diseases. Arthritis Rheum 2002;46:3340-8. (Pubitemid 35453546)
-
(2002)
Arthritis and Rheumatism
, vol.46
, Issue.12
, pp. 3340-3348
-
-
Aksentijevich, I.1
Nowak, M.2
Mallah, M.3
Chae, J.J.4
Watford, W.T.5
Hofmann, S.R.6
Stein, L.7
Russo, R.8
Goldsmith, D.9
Dent, P.10
Rosenberg, H.F.11
Austin, F.12
Remmers, E.F.13
Balow Jr., J.E.14
Rosenzweig, S.15
Komarow, H.16
Shoham, N.G.17
Wood, G.18
Jones, J.19
Mangra, N.20
Carrero, H.21
Adams, B.S.22
Moore, T.L.23
Schikler, K.24
Hoffman, H.25
Lovell, D.J.26
Lipnick, R.27
Barron, K.28
O'Shea, J.J.29
Kastner, D.L.30
Goldbach-Mansky, R.31
more..
-
7
-
-
5644230842
-
Enhanced interleukin-1beta and interleukin-18 release in a patient with chronic infantile neurologic, cutaneous, articular syndrome
-
DOI 10.1002/art.20494
-
Janssen R, Verhard E, Lankester A, et al. Enhanced interleukin-1beta and interleukin-18 release in a patient with chronic infantile neurologic, cutaneous, articular syndrome. Arthritis Rheum 2004;50:3329-33. (Pubitemid 39372011)
-
(2004)
Arthritis and Rheumatism
, vol.50
, Issue.10
, pp. 3329-3333
-
-
Janssen, R.1
Verhard, E.2
Lankester, A.3
Ten, C.R.4
Van Dissel, J.T.5
-
8
-
-
33746876396
-
Neonatal-onset multisystem inflammatory disease responsive to interleukin-1beta inhibition
-
DOI 10.1056/NEJMoa055137
-
Goldbach-Mansky R, Dailey NJ, Canna SW, et al. Neonatal-onset multisystem inflammatory disease responsive to interleukin-1beta inhibition. N Engl J Med 2006;355:581-92. (Pubitemid 44200651)
-
(2006)
New England Journal of Medicine
, vol.355
, Issue.6
, pp. 581-592
-
-
Goldbach-Mansky, R.1
Dailey, N.J.2
Canna, S.W.3
Gelabert, A.4
Jones, J.5
Rubin, B.I.6
Kim, H.J.7
Brewer, C.8
Zalewski, C.9
Wiggs, E.10
Hill, S.11
Turner, M.L.12
Karp, B.I.13
Aksentijevich, I.14
Pucino, F.15
Penzak, S.R.16
Haverkamp, M.H.17
Stein, L.18
Adams, B.S.19
Moore, T.L.20
Fuhlbrigge, R.C.21
Shaham, B.22
Jarvis, J.N.23
O'Neil, K.24
Vehe, R.K.25
Beitz, L.O.26
Gardner, G.27
Hannan, W.P.28
Warren, R.W.29
Horn, W.30
Cole, J.L.31
Paul, S.M.32
Hawkins, P.N.33
Tuyet, H.P.34
Snyder, C.35
Wesley, R.A.36
Hoffmann, S.C.37
Holland, S.M.38
Butman, J.A.39
Kastner, D.L.40
more..
-
9
-
-
1042290321
-
Spectrum of Clinical Features in Muckle-Wells Syndrome and Response to Anakinra
-
DOI 10.1002/art.20033
-
Hawkins PN, Lachmann HJ, Aganna E, et al. Spectrum of clinical features in Muckle-Wells syndrome and response to anakinra. Arthritis Rheum 2004;50:607-12. (Pubitemid 38198844)
-
(2004)
Arthritis and Rheumatism
, vol.50
, Issue.2
, pp. 607-612
-
-
Hawkins, P.N.1
Lachmann, H.J.2
Aganna, E.3
McDermott, M.F.4
-
10
-
-
0037792866
-
Interleukin-1-receptor antagonist in the Muckle-Wells syndrome
-
Hawkins PN, Lachmann HJ, McDermott MF. Interleukin-1-receptor antagonist in the Muckle-Wells syndrome. N Engl J Med 2003;348:2583-4.
-
(2003)
N Engl J Med
, vol.348
, pp. 2583-2584
-
-
Hawkins, P.N.1
Lachmann, H.J.2
McDermott, M.F.3
-
11
-
-
8444225132
-
Prevention of cold-associated acute inflammation in familial cold autoinflammatory syndrome by interleukin-1 receptor antagonist
-
DOI 10.1016/S0140-6736(04)17401-1, PII S0140673604174011
-
Hoffman HM, Rosengren S, Boyle DL, et al. Prevention of cold-associated acute inflammation in familial cold autoinflammatory syndrome by interleukin-1 receptor antagonist. Lancet 2004;364:1779-85. (Pubitemid 39488063)
-
(2004)
Lancet
, vol.364
, Issue.9447
, pp. 1779-1785
-
-
Hoffman, H.M.1
Rosengren, S.2
Boyle, D.L.3
Cho, J.Y.4
Nayar, J.5
Mueller, J.L.6
Anderson, J.P.7
Wanderer, A.A.8
Firestein, G.S.9
-
12
-
-
0036190776
-
Treatment of rheumatoid arthritis with anakinra, a recombinant human interleukin-1 receptor antagonist, in combination with methotrexate: Results of a twenty-four-week, multicenter, randomized, double-blind, placebo-controlled trial
-
DOI 10.1002/art.10141
-
Cohen S, Hurd E, Cush J, et al. Treatment of rheumatoid arthritis with anakinra, a recombinant human interleukin-1 receptor antagonist, in combination with methotrexate: results of a twenty-four-week, multicenter, randomized, double-blind, placebo-controlled trial. Arthritis Rheum 2002;46:614-24. (Pubitemid 34214243)
-
(2002)
Arthritis and Rheumatism
, vol.46
, Issue.3
, pp. 614-624
-
-
Cohen, S.1
Hurd, E.2
Cush, J.3
Schiff, M.4
Weinblatt, M.E.5
Moreland, L.W.6
Kremer, J.7
Bear, M.B.8
Rich, W.J.9
McCabe, D.10
-
13
-
-
49449094892
-
A pilot study to evaluate the safety and efficacy of the long-acting interleukin-1 inhibitor rilonacept (interleukin-1 Trap) in patients with familial cold autoinflammatory syndrome
-
Goldbach-Mansky R, Shroff SD, Wilson M, et al. A pilot study to evaluate the safety and efficacy of the long-acting interleukin-1 inhibitor rilonacept (interleukin-1 Trap) in patients with familial cold autoinflammatory syndrome. Arthritis Rheum 2008;58:2432-42.
-
(2008)
Arthritis Rheum
, vol.58
, pp. 2432-2442
-
-
Goldbach-Mansky, R.1
Shroff, S.D.2
Wilson, M.3
-
14
-
-
66649102432
-
Use of canakinumab in the cryopyrin-associated periodic syndrome
-
Lachmann HJ, Kone-Paut I, Kuemmerle-Deschner JB, et al. Use of canakinumab in the cryopyrin-associated periodic syndrome. N Engl J Med 2009;360:2416-25.
-
(2009)
N Engl J Med
, vol.360
, pp. 2416-2425
-
-
Lachmann, H.J.1
Kone-Paut, I.2
Kuemmerle-Deschner, J.B.3
-
15
-
-
66049094734
-
In vivo regulation of interleukin 1beta in patients with cryopyrin-associated periodic syndromes
-
Lachmann HJ, Lowe P, Felix SD, et al. In vivo regulation of interleukin 1beta in patients with cryopyrin-associated periodic syndromes. J Exp Med 2009;206:1029-36.
-
(2009)
J Exp Med
, vol.206
, pp. 1029-1036
-
-
Lachmann, H.J.1
Lowe, P.2
Felix, S.D.3
-
16
-
-
61749104104
-
The myeloid-related proteins 8 and 14 complex, a novel ligand of toll-like receptor 4, and interleukin-1beta form a positive feedback mechanism in systemic-onset juvenile idiopathic arthritis
-
Frosch M, Ahlmann M, Vogl T, et al. The myeloid-related proteins 8 and 14 complex, a novel ligand of toll-like receptor 4, and interleukin-1beta form a positive feedback mechanism in systemic-onset juvenile idiopathic arthritis. Arthritis Rheum 2009;60:883-91.
-
(2009)
Arthritis Rheum
, vol.60
, pp. 883-891
-
-
Frosch, M.1
Ahlmann, M.2
Vogl, T.3
-
17
-
-
34447131097
-
Mechanisms of Disease: A 'DAMP' view of inflammatory arthritis
-
DOI 10.1038/ncprheum0531, PII NCPRHEUM0531
-
Foell D, Wittkowski H, Roth J. Mechanisms of disease: a 'DAMP' view of inflammatory arthritis. Nat Clin Pract Rheumatol 2007;3:382-90. (Pubitemid 47034539)
-
(2007)
Nature Clinical Practice Rheumatology
, vol.3
, Issue.7
, pp. 382-390
-
-
Foell, D.1
Wittkowski, H.2
Roth, J.3
-
18
-
-
17144376810
-
High-mobility group box 1 protein (HMGB1): Nuclear weapon in the immune arsenal
-
DOI 10.1038/nri1594
-
Lotze MT, Tracey KJ. High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal. Nat Rev Immunol 2005;5:331-42. (Pubitemid 40516158)
-
(2005)
Nature Reviews Immunology
, vol.5
, Issue.4
, pp. 331-342
-
-
Lotze, M.T.1
Tracey, K.J.2
-
19
-
-
34948900275
-
Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock
-
DOI 10.1038/nm1638, PII NM1638
-
Vogl T, Tenbrock K, Ludwig S, et al. Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock. Nat Med 2007;13:1042-9. (Pubitemid 47517513)
-
(2007)
Nature Medicine
, vol.13
, Issue.9
, pp. 1042-1049
-
-
Vogl, T.1
Tenbrock, K.2
Ludwig, S.3
Leukert, N.4
Ehrhardt, C.5
Van Zoelen, M.A.D.6
Nacken, W.7
Foell, D.8
Van Der, P.T.9
Sorg, C.10
Roth, J.11
-
20
-
-
77953233075
-
The Toll-like receptor 4 ligands Mrp8 and Mrp14 are crucial in the development of autoreactive CD8+ T cells
-
Loser K, Vogl T, Voskort M, et al. The Toll-like receptor 4 ligands Mrp8 and Mrp14 are crucial in the development of autoreactive CD8+ T cells. Nat Med 2010;16:713-17.
-
(2010)
Nat Med
, vol.16
, pp. 713-717
-
-
Loser, K.1
Vogl, T.2
Voskort, M.3
-
21
-
-
77950512831
-
Methotrexate withdrawal at 6 vs 12 months in juvenile idiopathic arthritis in remission: A randomized clinical trial
-
Foell D, Wulffraat N, Wedderburn LR, et al. Methotrexate withdrawal at 6 vs 12 months in juvenile idiopathic arthritis in remission: a randomized clinical trial. JAMA 2010;303:1266-73.
-
(2010)
JAMA
, vol.303
, pp. 1266-1273
-
-
Foell, D.1
Wulffraat, N.2
Wedderburn, L.R.3
-
22
-
-
79953677480
-
Efficacy and safety of anakinra therapy in pediatric and adult patients with the autoinflammatory Muckle-Wells syndrome
-
Kuemmerle-Deschner JB, Tyrrell PN, Koetter I, et al. Efficacy and safety of anakinra therapy in pediatric and adult patients with the autoinflammatory Muckle-Wells syndrome. Arthritis Rheum 2011;63:840-9.
-
(2011)
Arthritis Rheum
, vol.63
, pp. 840-849
-
-
Kuemmerle-Deschner, J.B.1
Tyrrell, P.N.2
Koetter, I.3
-
23
-
-
7244221526
-
Early recruitment of phagocytes contributes to the vascular inflammation of giant cell arteritis
-
DOI 10.1002/path.1660
-
Foell D, Hernández-Rodríguez J, Sánchez M, et al. Early recruitment of phagocytes contributes to the vascular inflammation of giant cell arteritis. J Pathol 2004;204:311-16. (Pubitemid 39430091)
-
(2004)
Journal of Pathology
, vol.204
, Issue.3
, pp. 311-316
-
-
Foell, D.1
Hernandez-Rodriguez, J.2
Sanchez, M.3
Vogl, T.4
Cid, M.C.5
Roth, J.6
-
24
-
-
34250003794
-
Natural history and outcome in systemic AA amyloidosis
-
DOI 10.1056/NEJMoa070265
-
Lachmann HJ, Goodman HJ, Gilbertson JA, et al. Natural history and outcome in systemic AA amyloidosis. N Engl J Med 2007;356:2361-71. (Pubitemid 46883770)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.23
, pp. 2361-2371
-
-
Lachmann, H.J.1
Goodman, H.J.B.2
Gilbertson, J.A.3
Gallimore, J.R.4
Sabin, C.A.5
Gillmore, J.D.6
Hawkins, P.N.7
-
25
-
-
72749096954
-
Expression and role of myeloid-related protein-14 in clinical and experimental sepsis
-
van Zoelen MA, Vogl T, Foell D, et al. Expression and role of myeloid-related protein-14 in clinical and experimental sepsis. Am J Respir Crit Care Med 2009;180:1098-106.
-
(2009)
Am J Respir Crit Care Med
, vol.180
, pp. 1098-1106
-
-
Van Zoelen, M.A.1
Vogl, T.2
Foell, D.3
-
26
-
-
37149020133
-
Acute Kawasaki disease is associated with reverse regulation of soluble receptor for advance glycation end products and its proinflammatory ligand S100A12
-
DOI 10.1002/art.23042
-
Wittkowski H, Hirono K, Ichida F, et al. Acute Kawasaki disease is associated with reverse regulation of soluble receptor for advance glycation end products and its proinflammatory ligand S100A12. Arthritis Rheum 2007;56:4174-81. (Pubitemid 350262345)
-
(2007)
Arthritis and Rheumatism
, vol.56
, Issue.12
, pp. 4174-4181
-
-
Wittkowski, H.1
Hirono, K.2
Ichida, F.3
Vogl, T.4
Ye, F.5
Yanlin, X.6
Saito, K.7
Uese, K.8
Miyawaki, T.9
Viemann, D.10
Roth, J.11
Foell, D.12
-
27
-
-
2342506553
-
Myeloid related proteins MRP8/ MRP14 may predict disease flares in juvenile idiopathic arthritis
-
Schulze zur Wiesch A, Foell D, Frosch M, et al. Myeloid related proteins MRP8/ MRP14 may predict disease flares in juvenile idiopathic arthritis. Clin Exp Rheumatol 2004;22:368-73.
-
(2004)
Clin Exp Rheumatol
, vol.22
, pp. 368-373
-
-
Schulze Zur Wiesch, A.1
Foell, D.2
Frosch, M.3
-
28
-
-
0030898101
-
Myeloid-related protein (MRP) 8 and MRP14, calcium-binding proteins of the S100 family, are secreted by activated monocytes via a novel, tubulin- dependent pathway
-
DOI 10.1074/jbc.272.14.9496
-
Rammes A, Roth J, Goebeler M, et al. Myeloid-related protein (MRP) 8 and MRP14, calcium-binding proteins of the S100 family, are secreted by activated monocytes via a novel, tubulin-dependent pathway. J Biol Chem 1997;272:9496-502. (Pubitemid 27154966)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.14
, pp. 9496-9502
-
-
Rammes, A.1
Roth, J.2
Goebeler, M.3
Klempt, M.4
Hartmann, M.5
Sorg, C.6
-
29
-
-
0023200684
-
Two calcium-binding proteins in infiltrate macrophages of rheumatoid arthritis
-
DOI 10.1038/330080a0
-
Odink K, Cerletti N, Brüggen J, et al. Two calcium-binding proteins in infiltrate macrophages of rheumatoid arthritis. Nature 1987;330:80-2. (Pubitemid 17152420)
-
(1987)
Nature
, vol.330
, Issue.6143
, pp. 80-82
-
-
Odink, K.1
Cerletti, N.2
Bruggen, J.3
Clerc, R.G.4
Tarcsay, L.5
Zwadlo, G.6
Gerhards, G.7
Schlegel, R.8
Sorg, C.9
-
30
-
-
67649208478
-
The endogenous Toll-like receptor 4 agonist S100A8/S100A9 (calprotectin) as innate amplifier of infection, autoimmunity, and cancer
-
Ehrchen JM, Sunderkötter C, Foell D, et al. The endogenous Toll-like receptor 4 agonist S100A8/S100A9 (calprotectin) as innate amplifier of infection, autoimmunity, and cancer. J Leukoc Biol 2009;86:557-66.
-
(2009)
J Leukoc Biol
, vol.86
, pp. 557-566
-
-
Ehrchen, J.M.1
Sunderkötter, C.2
Foell, D.3
-
31
-
-
33845951211
-
DAMPs, PAMPs and alarmins: All we need to know about danger
-
DOI 10.1189/jlb.0306164
-
Bianchi ME. DAMPs, PAMPs and alarmins: all we need to know about danger. J Leukoc Biol 2007;81:1-5. (Pubitemid 46028489)
-
(2007)
Journal of Leukocyte Biology
, vol.81
, Issue.1
, pp. 1-5
-
-
Bianchi, M.E.1
-
32
-
-
0031892521
-
2 integrin Mac-1 on neutrophils
-
Newton RA, Hogg N. The human S100 protein MRP-14 is a novel activator of the beta 2 integrin Mac-1 on neutrophils. J Immunol 1998;160:1427-35. (Pubitemid 28093444)
-
(1998)
Journal of Immunology
, vol.160
, Issue.3
, pp. 1427-1435
-
-
Newton, R.A.1
Hogg, N.2
-
33
-
-
33947272221
-
MRP8/MRP14 impairs endothelial integrity and induces a caspase-dependent and -independent cell death program
-
DOI 10.1182/blood-2006-08-040444
-
Viemann D, Barczyk K, Vogl T, et al. MRP8/MRP14 impairs endothelial integrity and induces a caspase-dependent and -independent cell death program. Blood 2007;109:2453-60. (Pubitemid 46425888)
-
(2007)
Blood
, vol.109
, Issue.6
, pp. 2453-2460
-
-
Viemann, D.1
Barczyk, K.2
Vogl, T.3
Fischer, U.4
Sunderkotter, C.5
Schulze-Osthoff, K.6
Roth, J.7
|