Developmental exposure to organophosphates triggers transcriptional changes in genes associated with Parkinson's disease in vitro and in vivo

Brain Research Bulletin

Volumn 86, Issue 5-6, 2011, Pages 340-347

  Slotkin, Theodore A ^a   Seidler, Frederic J ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Chlorpyrifos; Diazinon; Dieldrin; Nickel; Organochlorine insecticides; Parkinson's disease

Indexed keywords

2 AMINO 3 CARBOXYMUCONATE 6 SEMIALDEHYDE DECARBOXYLASE; ALPHA SYNUCLEIN; ATPASE TYPE 13A; BETA GLUCOSIDASE 2; BETA GLUCOSIDASE 3; BONE MARROW STROMAL CELL ANTIGEN 1; CHLORPYRIFOS; CYCLIN G ASSOCIATED KINASE; DIELDRIN; DIMPYLATE; F BOX ONLY PROTEIN 7; FERTILITY PROTEIN SP22; HLA DR5 ANTIGEN; HUNTINGTIN INTERACTING PROTEIN 1 RELATED PROTEIN; LEUCINE RICH REPEAT KINASE 2; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 3; METHYLCROTONOYL COENZYME A CARBOXYLASE; METHYLCROTONOYL COENZYME A CARBOXYLASE 1 ALPHA; NICKEL; ORGANOPHOSPHATE PESTICIDE; PARKIN; PHOSPHOLIPASE A2 GROUP VI; PROTEIN; PTEN INDUCED KINASE 1; SERINE PROTEINASE OMI; SERINE THREONINE KINASE 39; SYNAPTOTAGMIN II; SYNPHILIN; TAU PROTEIN; UBIQUITIN CARBOXY TERMINAL HYDROLASE L1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN STEM; CONTROLLED STUDY; DOWN REGULATION; ENVIRONMENTAL EXPOSURE; FOREBRAIN; GENE EXPRESSION; GENETIC TRANSCRIPTION; IN VITRO STUDY; IN VIVO STUDY; MICROARRAY ANALYSIS; NERVE CELL DIFFERENTIATION; NEUROTOXICITY; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; PARKINSON DISEASE; PRIORITY JOURNAL; RAT; TISSUE MICROARRAY; UPREGULATION;

ANIMALS; ANIMALS, NEWBORN; BRAIN; CHLORPYRIFOS; CHOLINESTERASE INHIBITORS; DIAZINON; DIELDRIN; GENE EXPRESSION; GENE EXPRESSION PROFILING; HUMANS; MICROARRAY ANALYSIS; NICKEL; PARKINSON DISEASE; PC12 CELLS; PHOSPHORIC ACID ESTERS; RATS; TRANSCRIPTION, GENETIC;

EID: 82755197589     PISSN: 03619230     EISSN: 18732747     Source Type: Journal    
DOI: 10.1016/j.brainresbull.2011.09.017     Document Type: Article

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