Organophosphorus insecticides chlorpyrifos and diazinon and oxidative stress in neuronal cells in a genetic model of glutathione deficiency

Toxicology and Applied Pharmacology

Volumn 219, Issue 2-3, 2007, Pages 181-189

  Giordano, Gennaro ^a   Afsharinejad, Zhara ^a   Guizzetti, Marina ^a   Vitalone, Annabella ^b   Kavanagh, Terrance J ^a   Costa, Lucio G ^a,b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF PARMA   (Italy)

Author keywords

Glutathione; Organophosphorus insecticide; Oxidative stress; Reactive oxygen specie

Indexed keywords

2 HYDROXY 3,5,6 TRICHLORPYRIDINE; 2 ISOPROPYL 6 METHYL 4 PYRIMIDOL; ANTIOXIDANT; CHLORPYRIFOS; CHLORPYRIFOS OXON; CHOLINERGIC RECEPTOR BLOCKING AGENT; DIAZINON OXON; DIMPYLATE; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; GLUTATHIONE DISULFIDE; ORGANOPHOSPHATE INSECTICIDE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CALCIUM HOMEOSTASIS; CHELATION; CONTROLLED STUDY; GENETIC MODEL; GLUTATHIONE DEFICIENCY; GLUTATHIONE METABOLISM; GRANULE CELL; LIPID PEROXIDATION; MOUSE; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PROTEIN DEFICIENCY;

ANIMALS; CELL SURVIVAL; CELLS, CULTURED; CHLORPYRIFOS; DIAZINON; GLUTATHIONE; INSECTICIDES; LIPID PEROXIDATION; MICE; MICE, KNOCKOUT; MODELS, GENETIC; NEURONS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES;

ANIMALIA; MUS;

EID: 33847119357     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2006.09.016     Document Type: Article

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