Persistent organochlorine pesticides in serum and risk of Parkinson disease

Neurology

Volumn 74, Issue 13, 2010, Pages 1055-1061

  Weisskopf, M G ^a,b   Knekt, P ^c   O'Reilly, E J ^a   Lyytinen, J ^d   Reunanen, A ^c   Laden, F ^a,b   Altshul, L ^a   Ascherio, A ^a,b  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^d HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

1,1 DICHLORO 2,2 BIS(4 CHLOROPHENYL)ETHYLENE; CHLORPHENOTANE; DIELDRIN; HEPTACHLOR EPOXIDE; HEXACHLOROBENZENE; MIREX; NONACHLOR; ORGANOCHLORINE PESTICIDE; OXYCHLORDANE;

ADULT; ARTICLE; BLOOD SAMPLING; CIGARETTE SMOKING; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PARKINSON DISEASE; PRIORITY JOURNAL; PROSPECTIVE STUDY; RISK FACTOR;

EID: 77950200065     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/WNL.0b013e3181d76a93     Document Type: Article

References (40)

1. Brown TP, Rumsby PC, Capleton AC, Rushton L, Levy LS. Pesticides and Parkinson's disease: is there a link? Environ Health Perspect 2006;114:156-164.
2. Elbaz A, Tranchant C. Epidemiologic studies of environmental exposures in Parkinson's disease. J Neurol Sci 2007;262:37-44.
3. Hatcher JM, Pennell KD, Miller GW. Parkinson's disease and pesticides: a toxicological perspective. Trends Pharmacol Sci 2008;29:322-329.
4. Knekt P, Aromaa A, Maatela J, et al. Serum vitamin E and risk of cancer among Finnish men during a 10-year follow-up. Am J Epidemiol 1988;127:28-41.
5. Gelb DJ, Oliver E, Gilman S. Diagnostic criteria for Parkinson disease. Arch Neurol 1999;56:33-39.
6. Jankovic J. Parkinson's disease: clinical features and diagnosis. J Neurol Neurosurg Psychiatry 2008;79:368-376.
7. Schrag A, Ben-Shlomo Y, Quinn N. How valid is the clinical diagnosis of Parkinson's disease in the community? J Neurol Neurosurg Psychiatry 2002;73:529-534.
8. Korrick SA, Altshul LM, Tolbert PE, Burse VW, Need-ham LL, Monson RR. Measurement of PCBs, DDE, and hexachlorobenzene in cord blood from infants born in towns adjacent to a PCB-contaminated waste site. J Expo Anal Environ Epidemiol 2000;10:743-754.
9. Phillips DL, Pirkle JL, Burse VW, Bernert JT Jr, Henderson LO, Needham LL. Chlorinated hydrocarbon levels in human serum: effects of fasting and feeding. Arch Environ Contam Toxicol 1989;18:495-500.
10. Brookmeyer R, Liang KY, Linet M. Matched case-control designs and overmatched analyses. Am J Epidemiol 1986; 124:693-701.
11. Greenland S. Applications of stratified analysis methods. In: Rothman KJ, Greenland S, eds. Modern Epidemiology. Philadelphia: Lippincott-Raven; 1998:281-300.
12. National Center for Environmental Health, Centers for Disease Control and Prevention. Third National Report on Human Exposure to Environmental Chemicals. Atlanta: US Department of Health and Human Services. 2005. NCEH Pub. No. 05-0570.
13. Deutch B, Pedersen HS, Jorgensen EC, Hansen JC. Smoking as a determinant of high organochlorine levels in Greenland. Arch Environ Health 2003;58:30-36.
14. Gaffney SH, Curriero FC, Strickland PT, Glass GE, Hel-zlsouer KJ, Breysse PN. Influence of geographic location in modeling blood pesticide levels in a community surrounding a U.S. Environmental Protection Agency superfund site. Environ Health Perspect 2005;113:1712-1716.
15. Tanner CM, Ottman R, Goldman SM, et al. Parkinson disease in twins: an etiologic study. JAMA 1999;281:341-346.
16. Elbaz A, Clavel J, Rathouz PJ, et al. Professional exposure to pesticides and Parkinson's disease. Ann Neurol 2009;66:494-504.
17. Kanthasamy AG, Kitazawa M, Kanthasamy A, Anan-tharam V. Dieldrin-induced neurotoxicity: relevance to Parkinson's disease pathogenesis. Neurotoxicology 2005; 26:701-719.
18. Uversky VN, Li J, Fink AL. Pesticides directly accelerate the rate of alpha-synuclein fibril formation: a possible factor in Parkinson's disease. FEBS Lett 2001;500:105-108.
19. Hatcher JM, Richardson JR, Guillot TS, et al. Dieldrin exposure induces oxidative damage in the mouse nigrostri-atal dopamine system. Exp Neurol 2007;204:619-630.
20. Corrigan FM, Murray L, Wyatt CL, Shore RF. Diorthosub-stituted polychlorinated biphenyls in caudate nucleus in Parkinson's disease. Exp Neurol 1998;150:339-342.
21. Corrigan FM, Wienburg CL, Shore RF, Daniel SE, Mann D. Organochlorine insecticides in substantia nigra in Parkinson's disease. J Toxicol Environ Health A 2000;59:229-234.
22. Fleming L, Mann JB, Bean J, Briggle T, Sanchez-Ramos JR. Parkinson's disease and brain levels of organochlorine pesticides. Ann Neurol 1994;36:100-103.
23. Hatcher JM, Delea KC, Richardson JR, Pennell KD, Miller GW. Disruption of dopamine transport by DDT and its metabolites. Neurotoxicology 2008;29:682-690.
24. Hancock DB, Martin ER, Mayhew GM, et al. Pesticide exposure and risk of Parkinson's disease: a family-based case-control study. BMC Neurol 2008;8:6.
25. Seidler A, Hellenbrand W, Robra B-P, et al. Possible environmental, occupational, and other etiologic factors for Parkinson's disease: a case-control study in Germany. Neurology 1996;46:1275-1284.
26. Tanner CM, Ross GW, Jewell SA, et al. Occupation and risk of parkinsonism: a multicenter case-control study. Arch Neurol 2009;66:1106-1113.
27. Kamel F, Tanner C, Umbach D, et al. Pesticide exposure and self-reported Parkinson's disease in the agricultural health study. Am J Epidemiol 2007;165:364-374.
28. Kuopio AM, Marttila RJ, Helenius H, Rinne UK. Environmental risk factors in Parkinson's disease. Mov Disord 1999;14:928-939.
29. Koldkjaer OG, Wermuth L, Bjerregaard P. Parkinson's disease among Inuit in Greenland: organochlorines as risk factors. Int J Circumpolar Health 2004;63(suppl 2):366-368.
30. Petersen MS, Halling J, Bech S, et al. Impact of dietary exposure to food contaminants on the risk of Parkinson's disease. Neurotoxicology 2008;29:584-590.
31. Richardson JR, Shalat SL, Buckley B, et al. Elevated serum pesticide levels and risk of Parkinson disease. Arch Neurol 2009;66:870-875.
32. National Implementation Plan for the Stockholm Convention on Persistent Organic Pollutants: Finland. Available at: http://chm.pops.int/Countries/ NationalImplementation/ tabid/253/language/en-US/Default.aspx. Accessed October 5, 2009.
33. Markkula M, Tiittanen K, Vasarainen A. Pesticides in Agriculture and Forestry 1953-1987 [in Finnish]. Joikioinen, Finland: Agriculture Research Center, Research Institute of Plant Protection; 1990. Bulletin 2/90.
34. Agency for Toxic Substances and Disease Registry. Toxi-cological Profile for Mirex and Chlordecone. Atlanta: US Department of Health and Human Services, Public Health Service. 1995.
35. Agency for Toxic Substances and Disease Registry. Toxi-cological Profile for DDD/DDT/DDE. Atlanta: US Department of Health and Human Services, Public Health Service. 2001.
36. Agency for Toxic Substances and Disease Registry. Toxi-cological Profile for Hexachlorobenzene. Atlanta: US Department of Health and Human Services, Public Health Service 2002.
37. Agency for Toxic Substances and Disease Registry. Toxi-cological Profile for Hexachlorocyclohexane. Atlanta: US Department of Health and Human Services, Public Health Service. 2005.
38. Arctic Monitoring and Assessment Programme. Persistent Organic Pollutants (POPs). Oslo: Arctic Monitoring and Assessment Programme; 1998.
39. Costello S, Cockburn M, Bronstein J, Zhang X, Ritz B. Parkinson's disease and residential exposure to maneb and paraquat from agricultural applications in the central valley of California. Am J Epidemiol 2009;169:919-926.
40. Hughes AJ, Daniel SE, Lees AJ. Improved accuracy of clinical diagnosis of Lewy body Parkinson's disease. Neurology 2001;57:1497-1499.