ΔfosB enhances the rewarding effects of cocaine while reducing the pro-depressive effects of the kappa-opioid receptor agonist U50488

Biological Psychiatry

Volumn 71, Issue 1, 2012, Pages 44-50

  Muschamp, John W ^a   Nemeth, Christina L ^a   Robison, Alfred J ^b   Nestler, Eric J ^b   Carlezon Jr , William A ^a  

^a MCLEAN HOSPITAL   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Addiction; brain stimulation reward; model; mouse; nucleus accumbens; resilience; stress; transcription factor

Indexed keywords

3,4 DICHLORO N METHYL N [2 (1 PYRROLIDINYL)CYCLOHEXYL]BENZENEACETAMIDE; COCAINE; TRANSCRIPTION FACTOR DELTA FOSB;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; DOSE RESPONSE; DRUG EFFECT; DRUG INDUCED DISEASE; DYSPHORIA; ELECTRODE; MALE; MOUSE; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SELF STIMULATION; STRESS;

3,4-DICHLORO-N-METHYL-N-(2-(1-PYRROLIDINYL)-CYCLOHEXYL)-BENZENEACETAMIDE, (TRANS)-ISOMER; ANESTHETICS, LOCAL; ANIMALS; BIOPHYSICS; COCAINE; CONDITIONING, OPERANT; CORPUS STRIATUM; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; HYPOTHALAMIC AREA, LATERAL; MALE; MEDIAL FOREBRAIN BUNDLE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PHOSPHOPYRUVATE HYDRATASE; PROTO-ONCOGENE PROTEINS C-FOS; RECEPTORS, OPIOID, KAPPA; REWARD; SELF STIMULATION;

EID: 82755182552     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2011.08.011     Document Type: Article

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