Corepressor protein CDYL functions as a molecular bridge between polycomb repressor complex 2 and repressive chromatin mark trimethylated histone lysine 27

Journal of Biological Chemistry

Volumn 286, Issue 49, 2011, Pages 42414-42425

  Zhang, Yu ^a   Yang, Xiaohan ^a   Gui, Bin ^a   Xie, Guojia ^a   Zhang, Di ^a   Shang, Yongfeng ^a,b   Liang, Jing ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b TIANJIN MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYTIC SUBUNITS; COREPRESSORS; ENZYMATIC ACTIVITIES; HISTONE H3; IN-VITRO; METHYLTRANSFERASE ACTIVITY; MOLECULAR BRIDGES; MULTIPLE GENES; OLIGONUCLEOSOME; PATHOPHYSIOLOGICAL; POLYCOMB; POLYCOMB GROUP PROTEINS; POSITIVE FEEDBACK LOOP; TARGET SITES; TRANSCRIPTIONAL REGULATION;

AMINO ACIDS; CHROMOSOMES; ENZYME ACTIVITY; FEEDBACK; GENE EXPRESSION;

PROTEINS;

CDYL PROTEIN; COREPRESSOR PROTEIN; HISTONE H3; METHYLTRANSFERASE; POLYCOMB REPRESSOR COMPLEX 2; TRANSCRIPTION FACTOR EZH2; TRIMETHYLATED HISTONE H3 LYSINE 27; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CHROMATIN; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME SUBSTRATE; GENE REPRESSION; GENETIC ANALYSIS; HISTONE MODIFICATION; HUMAN; HUMAN CELL; IN VITRO STUDY; NONHUMAN; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION;

ANIMALS; CATALYTIC DOMAIN; CELL LINE, TUMOR; CHROMATIN; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION; HISTONES; HUMANS; LYSINE; METHYLATION; METHYLTRANSFERASES; NUCLEOSOMES; PROTEINS; REPRESSOR PROTEINS; XENOPUS;

EID: 82755176823     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.271064     Document Type: Article

References (55)

1. Berger, S. L. (2007) Nature 447, 407-412
2. Campos, E. I., and Reinberg, D. (2009) Annu. Rev. Genet. 43, 559-599
3. Kouzarides, T. (2007) Cell 128, 693-705
4. Wang, Y., Zhang, H., Chen, Y., Sun, Y., Yang, F., Yu, W., Liang, J., Sun, L., Yang, X., Shi, L., Li, R., Li, Y., Zhang, Y., Li, Q., Yi, X., and Shang, Y. (2009) Cell 138, 660-672
5. Kleer, C. G., Cao, Q., Varambally, S., Shen, R., Ota, I., Tomlins, S. A., Ghosh, D., Sewalt, R. G., Otte, A. P., Hayes, D. F., Sabel, M. S., Livant, D., Weiss, S. J., Rubin, M. A., and Chinnaiyan, A. M. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 11606-11611
6. Bracken, A. P., Dietrich, N., Pasini, D., Hansen, K. H., and Helin, K. (2006) Genes Dev. 20, 1123-1136
7. Lee, T. I., Jenner, R. G., Boyer, L. A., Guenther, M. G., Levine, S. S., Kumar, R. M., Chevalier, B., Johnstone, S. E., Cole, M. F., Isono, K., Koseki, H., Fuchikami, T., Abe, K., Murray, H. L., Zucker, J. P., Yuan, B., Bell, G. W., Herbolsheimer, E., Hannett, N. M., Sun, K., Odom, D. T., Otte, A. P., Volkert, T. L., Bartel, D. P., Melton, D. A., Gifford, D. K., Jaenisch, R., and Young, R. A. (2006) Cell 125, 301-313
8. Margueron, R., and Reinberg, D. (2011) Nature 469, 343-349
9. Cao, R., Wang, L., Wang, H., Xia, L., Erdjument-Bromage, H., Tempst, P., Jones, R. S., and Zhang, Y. (2002) Science 298, 1039-1043
10. Müller, J., Hart, C. M., Francis, N. J., Vargas, M. L., Sengupta, A., Wild, B., Miller, E. L., O'Connor, M. B., Kingston, R. E., and Simon, J. A. (2002) Cell 111, 197-208
11. Zhang, Y., Cao, R., Wang, L., and Jones, R. S. (2004) Cold Spring Harb. Symp. Quant. Biol. 69, 309-317
12. Kuzmichev, A., Nishioka, K., Erdjument-Bromage, H., Tempst, P., and Reinberg, D. (2002) Genes Dev. 16, 2893-2905
13. Tolhuis, B., de Wit, E., Muijrers, I., Teunissen, H., Talhout, W., van Steensel, B., and van Lohuizen, M. (2006) Nat. Genet. 38, 694-699
14. Wang, H., Wang, L., Erdjument-Bromage, H., Vidal, M., Tempst, P., Jones, R. S., and Zhang, Y. (2004) Nature 431, 873-878
15. Schoeftner, S., Sengupta, A. K., Kubicek, S., Mechtler, K., Spahn, L., Koseki, H., Jenuwein, T., and Wutz, A. (2006) EMBO J. 25, 3110-3122
16. Sing, A., Pannell, D., Karaiskakis, A., Sturgeon, K., Djabali, M., Ellis, J., Lipshitz, H. D., and Cordes, S. P. (2009) Cell 138, 885-897
17. Ku, M., Koche, R. P., Rheinbay, E., Mendenhall, E. M., Endoh, M., Mikkelsen, T. S., Presser, A., Nusbaum, C., Xie, X., Chi, A. S., Adli, M., Kasif, S., Ptaszek, L. M., Cowan, C. A., Lander, E. S., Koseki, H., and Bernstein, B. E. (2008) PLoS Genet. 4, e1000242
18. Taverna, S. D., Li, H., Ruthenburg, A. J., Allis, C. D., and Patel, D. J. (2007) Nat. Struct. Mol. Biol. 14, 1025-1040
19. Goldberg, A. D., Allis, C. D., and Bernstein, E. (2007) Cell 128, 635-638
20. Kim, J., Daniel, J., Espejo, A., Lake, A., Krishna, M., Xia, L., Zhang, Y., and Bedford, M. T. (2006) EMBO Rep. 7, 397-403
21. Caron, C., Pivot-Pajot, C., van Grunsven, L. A., Col, E., Lestrat, C., Rousseaux, S., and Khochbin, S. (2003) EMBO Rep. 4, 877-882
22. Dorus, S., Gilbert, S. L., Forster, M. L., Barndt, R. J., and Lahn, B. T. (2003) Hum. Mol. Genet. 12, 1643-1650
23. Shi, Y., Sawada, J., Sui, G., Affar el, B., Whetstine, J. R., Lan, F., Ogawa, H., Luke, M. P., Nakatani, Y., and Shi, Y. (2003) Nature 422, 735-738
24. Mulligan, P., Westbrook, T. F., Ottinger, M., Pavlova, N., Chang, B., Macia, E., Shi, Y. J., Barretina, J., Liu, J., Howley, P. M., Elledge, S. J., and Shi, Y. (2008) Mol. Cell 32, 718-726
25. Shi, X., Hong, T., Walter, K. L., Ewalt, M., Michishita, E., Hung, T., Carney, D., Peña, P., Lan, F., Kaadige, M. R., Lacoste, N., Cayrou, C., Davrazou, F., Saha, A., Cairns, B. R., Ayer, D. E., Kutateladze, T. G., Shi, Y., Côté, J., Chua, K. F., and Gozani, O. (2006) Nature 442, 96-99
26. Luger, K., Rechsteiner, T. J., Flaus, A. J., Waye, M. M., and Richmond, T. J. (1997) J. Mol. Biol. 272, 301-311
27. Iwase, S., Lan, F., Bayliss, P., de la Torre-Ubieta, L., Huarte, M., Qi, H. H., Whetstine, J. R., Bonni, A., Roberts, T. M., and Shi, Y. (2007) Cell 128, 1077-1088
28. Zhang, Y., Liu, T., Meyer, C. A., Eeckhoute, J., Johnson, D. S., Bernstein, B. E., Nusbaum, C., Myers, R. M., Brown, M., Li, W., and Liu, X. S. (2008) Genome Biol. 9, R137
29. Wu, H., Chen, Y., Liang, J., Shi, B., Wu, G., Zhang, Y., Wang, D., Li, R., Yi, X., Zhang, H., Sun, L., and Shang, Y. (2005) Nature 438, 981-987
30. Shi, B., Liang, J., Yang, X., Wang, Y., Zhao, Y., Wu, H., Sun, L., Zhang, Y., Chen, Y., Li, R., Zhang, Y., Hong, M., and Shang, Y. (2007) Mol. Cell Biol. 27, 5105-5119
31. Zhang, H., Yi, X., Sun, X., Yin, N., Shi, B., Wu, H., Wang, D., Wu, G., and Shang, Y. (2004) Genes Dev. 18, 1753-1765
32. Yin, N., Wang, D., Zhang, H., Yi, X., Sun, X., Shi, B., Wu, H., Wu, G., Wang, X., and Shang, Y. (2004) Cancer Res. 64, 5870-5875
33. Li, R., Zhang, H., Yu, W., Chen, Y., Gui, B., Liang, J., Wang, Y., Sun, L., Yang, X., Zhang, Y., Shi, L., Li, Y., and Shang, Y. (2009) EMBO J. 28, 2763-2776
34. Luger, K., Rechsteiner, T. J., and Richmond, T. J. (1999) Methods Enzymol. 304, 3-19
35. Sims, R. J., 3rd, Trojer, P., Li, G., and Reinberg, D. (2006) Methods 40, 331-338
36. Loyola, A., and Reinberg, D. (2003) Methods 31, 96-103
37. Sarma, K., Margueron, R., Ivanov, A., Pirrotta, V., and Reinberg, D. (2008) Mol. Cell Biol. 28, 2718-2731
38. Shang, Y., Hu, X., DiRenzo, J., Lazar, M. A., and Brown, M. (2000) Cell 103, 843-852
39. Li, X., Liang, J., Yu, H., Su, B., Xiao, C., Shang, Y., and Wang, W. (2007) Trends Genet. 23, 427-431
40. Kuppuswamy, M., Vijayalingam, S., Zhao, L. J., Zhou, Y., Subramanian, T., Ryerse, J., and Chinnadurai, G. (2008) Mol. Cell Biol. 28, 269-281
41. Franz, H., Mosch, K., Soeroes, S., Urlaub, H., and Fischle, W. (2009) J. Biol. Chem. 284, 35049-35059
42. Vermeulen, M., Eberl, H. C., Matarese, F., Marks, H., Denissov, S., Butter, F., Lee, K. K., Olsen, J. V., Hyman, A. A., Stunnenberg, H. G., and Mann, M. (2010) Cell 142, 967-980
43. Shi, L., Sun, L., Li, Q., Liang, J., Yu, W., Yi, X., Yang, X., Li, Y., Han, X., Zhang, Y., Xuan, C., Yao, Z., and Shang, Y. (2011) Proc. Natl. Acad. Sci. U.S.A. 108, 7541-7546
44. Margueron, R., Justin, N., Ohno, K., Sharpe, M. L., Son, J., Drury, W. J., 3rd, Voigt, P., Martin, S. R., Taylor, W. R., De Marco, V., Pirrotta, V., Reinberg, D., and Gamblin, S. J. (2009) Nature 461, 762-767
45. Xu, C., Bian, C., Yang, W., Galka, M., Ouyang, H., Chen, C., Qiu, W., Liu, H., Jones, A. E., MacKenzie, F., Pan, P., Li, S. S., Wang, H., and Min, J. (2010) Proc. Natl. Acad. Sci. U.S.A. 107, 19266-19271
46. Ji, X., Li, W., Song, J., Wei, L., and Liu, X. S. (2006) Nucleic Acids Res. 34(Web Server issue), W551-W554
47. Bailey, T. L., and Elkan, C. (1994) Proc. Int. Conf Intell Syst Mol. Biol. 2, 28-36
48. Mori, N., Schoenherr, C., Vandenbergh, D. J., and Anderson, D. J. (1992) Neuron 9, 45-54
49. Mortazavi, A., Leeper Thompson, E. C., Garcia, S. T., Myers, R. M., and Wold, B. (2006) Genome Res. 16, 1208-1221
50. Joseph, R., Orlov, Y. L., Huss, M., Sun, W., Kong, S. L., Ukil, L., Pan, Y. F., Li, G., Lim, M., Thomsen, J. S., Ruan, Y., Clarke, N. D., Prabhakar, S., Cheung, E., and Liu, E. T. (2010) Mol. Syst Biol. 6, 456
51. Tan, J., Yang, X., Zhuang, L., Jiang, X., Chen, W., Lee, P. L., Karuturi, R. K., Tan, P. B., Liu, E. T., and Yu, Q. (2007) Genes Dev. 21, 1050-1063
52. Cao, R., Wang, H., He, J., Erdjument-Bromage, H., Tempst, P., and Zhang, Y. (2008) Mol. Cell Biol. 28, 1862-1872
53. Moazed, D. (2011) Cell 146, 510-518
54. Dodd, I. B., Micheelsen, M. A., Sneppen, K., and Thon, G. (2007) Cell 129, 813-822
55. Kaufman, P. D., and Rando, O. J. (2010) Curr. Opin. Cell Biol. 22, 284-290