Soluble CD14 and CD14 polymorphisms in rheumatoid arthritis

Journal of Rheumatology

Volumn 38, Issue 12, 2011, Pages 2509-2516

  Mikuls, Ted R ^a   LeVan, Tricia D ^b   Sayles, Harlan ^b   Yu, Fang ^b   Caplan, Liron ^c   Cannon, Grant W ^d   Kerr, Gail S ^e   Reimold, Andreas M ^f   Johnson, Dannette S ^g   Thiele, Geoffrey M ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^c UNIVERSITY OF COLORADO   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

^e VETERANS AFFAIRS MEDICAL CENTER   (United States)

^f UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^g G V SONNY MONTGOMERY VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Acute phase response; Disease activity; Disease severity; Polymorphisms; Rheumatoid arthritis; Soluble CD14

Indexed keywords

C REACTIVE PROTEIN; CD14 ANTIGEN; GENOMIC DNA;

ADULT; AFRICAN AMERICAN; AGE DISTRIBUTION; ANTIGEN EXPRESSION; ARTICLE; BODY MASS; CAUCASIAN; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DISEASE ACTIVITY; DISEASE ACTIVITY SCORE; DISEASE SEVERITY; FEMALE; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC VARIABILITY; HUMAN; INNATE IMMUNITY; MAJOR CLINICAL STUDY; MALE; MOLECULAR PATHOLOGY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RACE DIFFERENCE; RHEUMATOID ARTHRITIS; SCORING SYSTEM; SINGLE NUCLEOTIDE POLYMORPHISM;

AGED; ANTIGENS, CD14; ARTHRITIS, RHEUMATOID; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; IMMUNITY, INNATE; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; SEVERITY OF ILLNESS INDEX;

EID: 82755176615     PISSN: 0315162X     EISSN: 14992752     Source Type: Journal    
DOI: 10.3899/jrheum.110378     Document Type: Article

References (48)

1. Huang QQ, Pope RM. The role of toll-like receptors in rheumatoid arthritis. Curr Rheumatol Rep 2009;11:357-64.
2. Pugin J, Heumann ID, Tomasz A, Kravchenko VV, Akamatsu Y, Nishijima M, et al. CD14 is a pattern recognition receptor. Immunity 1994;1:509-16.
3. Kitchens RL, Thompson PA. Modulatory effects of sCD14 and LBP on LPS-host cell interactions. J Endotoxin Res 2005;11:225-9. (Pubitemid 41358857)
4. Abdollahi-Roodsaz S, Joosten LA, Roelofs MF, Radstake TR, Matera G, Popa C, et al. Inhibition of Toll-like receptor 4 breaks the inflammatory loop in autoimmune destructive arthritis. Arthritis Rheum 2007;56:2957-67. (Pubitemid 47502742)
5. Bas S, Gauthier BR, Spenato U, Stingelin S, Gabay C. CD14 is an acute-phase protein. J Immunol 2004;172:4470-9. (Pubitemid 38375263)
6. Horneff G, Sack U, Kalden JR, Emmrich F, Burmester GR. Reduction of monocyte-macrophage activation markers upon anti-CD4 treatment. Decreased levels of IL-1, IL-6, neopterin and soluble CD14 in patients with rheumatoid arthritis. Clin Exp Immunol 1993;91:207-13. (Pubitemid 23045663)
7. Yu S, Nakashima N, Xu BH, Matsuda T, Izumihara A, Sunahara N, et al. Pathological significance of elevated soluble CD14 production in rheumatoid arthritis: in the presence of soluble CD14, lipopolysaccharides at low concentrations activate RA synovial fibroblasts. Rheumatol Int 1998;17:237-43. (Pubitemid 28192760)
8. Nicu EA, Laine ML, Morre SA, van der Velden U, Loos BG. Soluble CD14 in periodontitis. Innate Immun 2009;15:121-8.
9. Wuthrich B, Kagi MK, Joller-Jemelka H. Soluble CD14 but not interleukin-6 is a new marker for clinical activity in atopic dermatitis. Arch Dermatol Res 1992;284:339-42.
10. Egerer K, Feist E, Rohr U, Pruss A, Burmester GR, Dorner T. Increased serum soluble CD14, ICAM-1 and E-selectin correlate with disease activity and prognosis in systemic lupus erythematosus. Lupus 2000;9:614-21.
11. Takeshita S, Nakatani K, Tsujimoto H, Kawamura Y, Kawase H, Sekine I. Increased levels of circulating soluble CD14 in Kawasaki disease. Clin Exp Immunol 2000;119:376-81. (Pubitemid 30073045)
12. Guerra S, Carla Lohman I, LeVan TD, Wright AL, Martinez FD, Halonen M. The differential effect of genetic variation on soluble CD14 levels in human plasma and milk. Am J Reprod Immunol 2004;52:204-11. (Pubitemid 39359415)
13. LeVan TD, Guerra S, Klimecki W, Vasquez MM, Lohman IC, Martinez FD, et al. The impact of CD14 polymorphisms on the development of soluble CD14 levels during infancy. Genes Immun 2006;7:77-80.
14. Koenig W, Khuseyinova N, Hoffmann MM, Marz W, Frohlich M, Hoffmeister A, et al. CD14 C(-260)- >T polymorphism, plasma levels of the soluble endotoxin receptor CD14, their association with chronic infections and risk of stable coronary artery disease. J Am Coll Cardiol 2002;40:34-42. (Pubitemid 34701374)
15. LeVan TD, Michel O, Dentener M, Thorn J, Vertongen F, Beijer L, et al. Association between CD14 polymorphisms and serum soluble CD14 levels: effect of atopy and endotoxin inhalation. J Allergy Clin Immunol 2008;121:434-40.
16. Mikuls TR, Kazi S, Cipher D, Hooker R, Kerr GS, Richards JS, et al. The association of race and ethnicity with disease expression in male US veterans with rheumatoid arthritis. J Rheumatol 2007;34:1480-4. (Pubitemid 47067982)
17. Miriovsky BJ, Michaud K, Thiele GM, O'Dell J, Cannon GW, Kerr G, et al. Anti-CCP antibody and rheumatoid factor concentrations predict greater disease burden in U.S. veterans with rheumatoid arthritis. Ann Rheum Dis 2010;69:1292-7.
18. Arnett F, Edworthy S, Bloch D, McShane D, Fries J, Cooper N, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988;31:315-24. (Pubitemid 18091653)
19. Mikuls TR, Payne JB, Reinhardt RA, Thiele GM, Maziarz E, Cannella AC, et al. Antibody responses to Porphyromonas gingivalis (P. gingivalis) in subjects with rheumatoid arthritis and periodontitis. Int Immunopharmacol 2009;9:38-42.
20. Ramachandran P, Heires AJ, DeSpiegelaere H, Romberger D, LeVan DT. TNF production in whole blood is inversely associated with lung function among veterans with agricultural work exposure [abstract]. Chest 2007;132:600a.
21. Pauwels RA, Buist AS, Calverley PMA, Jenkins CR, Hurd SS. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) Workshop Summary. Am J Respir Crit Care Med 2001;163:1256-76. (Pubitemid 32378468)
22. Brass DM, Hollingsworth JW, McElvania-Tekippe E, Garantziotis S, Hossain I, Schwartz DA. CD14 is an essential mediator of LPS-induced airway disease. Am J Physiol Lung Cell Mol Physiol 2007;293:L77-83. (Pubitemid 47080715)
23. Regueiro V, Campos MA, Morey P, Sauleda J, Agusti AG, Garmendia J, et al. Lipopolysaccharide-binding protein and CD14 are increased in the bronchoalveolar lavage fluid of smokers. Eur Respir J 2009;33:273-81.
24. Mikuls TR, Gould KA, Bynote KK, Yu F, LeVan TD, Thiele GM, et al. Anticitrullinated protein antibody (ACPA) in rheumatoid arthritis: influence of an interaction between HLA-DRB1 shared epitope and a deletion polymorphism in glutathione s-transferase in a cross-sectional study. Arthritis Res Ther 2010;12:R213.
25. Pincus T, Swearingen C, Wolfe F. Toward a multidimensional Health Assessment Questionnaire (MDHAQ): assessment of advanced activities of daily living and psychological status in the patient-friendly Health Assessment Questionnaire format. Arthritis Rheum 1999;42:2220-30. (Pubitemid 30263609)
26. Prevoo ML, van 't Hof MA, Kuper HH, van Leeuwen MA, van de Putte LB, van Riel PL. Modified disease activity scores that include twenty-eight-joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis. Arthritis Rheum 1995;38:44-8.
27. van Gestel AM, Prevoo ML, van 't Hof MA, van Rijswijk MH, van de Putte LB, van Riel PL. Development and validation of the European League Against Rheumatism response criteria for rheumatoid arthritis. Comparison with the preliminary American College of Rheumatology and the World Health Organization/International League Against Rheumatism criteria. Arthritis Rheum 1996;39:34-40. (Pubitemid 26036375)
28. Lazarus R, Vercelli D, Palmer LJ, Klimecki WJ, Silverman EK, Richter B, et al. Single nucleotide polymorphisms in innate immunity genes: abundant variation and potential role in complex human disease. Immunol Rev 2002;190:9-25. (Pubitemid 36071923)
29. Carlson CS, Eberle MA, Rieder MJ, Yi Q, Kruglyak L, Nickerson DA. Selecting a maximally informative set of single-nucleotide polymorphisms for association analyses using linkage disequilibrium. Am J Hum Genet 2004;74:106-20. (Pubitemid 38085242)
30. McCullagh P, Nelder J. Generalized linear models. 2nd ed. London: Chapman & Hall; 1989.
31. Brant R. Assessing proportionality in the proportional odds model for ordinal logistic regression. Biometrics 1990;46:1171-8.
32. Pincus T, Swearingen CJ, Bergman M, Yazici Y. RAPID3 (Routine Assessment of Patient Index Data 3), a rheumatoid arthritis index without formal joint counts for routine care: Proposed severity categories compared to Disease Activity Score and Clinical Disease Activity Index categories. J Rheumatol 2008;35:2136-47.
33. Whitehead J. Sample size calculations for ordered categorical data. Stat Med 1993;12:2257-71. (Pubitemid 24007147)
34. U.S. Department of Veterans Affairs. 2001 National survey of veterans. [Internet. Accessed Aug 26, 2011.] Available from: http://www.virec.research.va. gov/DataSourcesName/National SurveyVeterans/2001NationalSurveyofVeterans.html
35. National Institutes of Health. [Internet. Accessed Aug 26, 2011.] Available from: http://ncbi.nlm.nih.gov/SNP/index.html
36. Heumann D, Glauser MP, Calandra T. Molecular basis of host-pathogen interaction in septic shock. Curr Opin Microbiol 1998;1:49-55. (Pubitemid 128428042)
37. Devitt A, Pierce S, Oldreive C, Shingler WH, Gregory CD. CD14-dependent clearance of apoptotic cells by human macrophages: the role of phosphatidylserine. Cell Death Differ 2003;10:371-82. (Pubitemid 36582375)
38. Frey EA, Finlay BB. Lipopolysaccharide induces apoptosis in a bovine endothelial cell line via a soluble CD14 dependent pathway. Microb Pathog 1998;24:101-9. (Pubitemid 28085626)
39. Hu X, Yee E, Harlan JM, Wong F, Karsan A. Lipopolysaccharide induces the antiapoptotic molecules, A1 and A20, in microvascular endothelial cells. Blood 1998;92:2759-65. (Pubitemid 28469089)
40. Arias MA, Rey Nores JE, Vita N, Stelter F, Borysiewicz LK, Ferrara P, et al. Cutting edge: human B cell function is regulated by interaction with soluble CD14: opposite effects on IgG1 and IgE production. J Immunol 2000;164:3480-6.
41. Rey Nores JE, Bensussan A, Vita N, Stelter F, Arias MA, Jones M, et al. Soluble CD14 acts as a negative regulator of human T cell activation and function. Eur J Immunol 1999;29:265-76. (Pubitemid 29043544)
42. Hilder FM, Gunz FW. The effect of age on normal values of the Westergen sedimentation rate. J Clin Pathol 1964;17:292-3.
43. Milman N, Graudal N, Andersen HC. Acute phase reactants in the elderly. Clin Chim Acta 1988;176:59-62.
44. Wilhelm WF, Tillisch JH. Relation of sedimentation rate to age. Med Clin North Am 1951;1:1209-11.
45. Renvert S, Ohlsson O, Pettersson T, Persson GR. Periodontitis: a future risk of acute coronary syndrome? A follow-up study over 3 years. J Periodontol 2010;81:992-1000.
46. Kitchens RL, Thompson PA, Viriyakosol S, O'Keefe GE, Munford RS. Plasma CD14 decreases monocyte responses to LPS by transferring cell-bound LPS to plasma lipoproteins. J Clin Invest 2001;108:485-93. (Pubitemid 32730795)
47. Lakio L, Lehto M, Tuomainen AM, Jauhiainen M, Malle E, Asikainen S, et al. Pro-atherogenic properties of lipopolysaccharide from the periodontal pathogen Actinobacillus actinomycetemcomitans. J Endotoxin Res 2006;12:57-64. (Pubitemid 43169514)
48. Snow MH, Mikuls TR. Rheumatoid arthritis and cardiovascular disease: the role of systemic inflammation and evolving strategies of prevention. Curr Opin Rheumatol 2005;17:234-41. (Pubitemid 40616568)