CD14 C(-260)→T polymorphism, plasma levels of the soluble endotoxin receptor CD14, their association with chronic infections and risk of stable coronary artery disease

Journal of the American College of Cardiology

Volumn 40, Issue 1, 2002, Pages 34-42

  Koenig, Wolfgang ^a   Khuseyinova, Natalie ^a   Hoffmann, Michael M ^b   März, Winfried ^b   Fröhlich, Margit ^a   Hoffmeister, Albrecht ^a   Brenner, Hermann ^c,d   Rothenbacher, Dietrich ^c,d  

^a UNIVERSITY HOSPITAL ULM   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

^c UNIVERSITY OF ULM   (Germany)

^d GERMAN CENTRE FOR RESEARCH ON AGEING   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CD14 ANTIGEN; CYTOSINE; THYMINE;

ADULT; ANGINA PECTORIS; ARTICLE; ATHEROGENESIS; BLOOD; CHLAMYDOPHILA PNEUMONIAE; CONFIDENCE INTERVAL; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DISEASE ASSOCIATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE EXPRESSION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; GERMANY; HELICOBACTER PYLORI; HUMAN; HUMAN TISSUE; INFECTION; INFLAMMATION; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RISK ASSESSMENT; RISK FACTOR; SERODIAGNOSIS;

ANGINA PECTORIS; ANTIGENS, CD14; CASE-CONTROL STUDIES; CHLAMYDOPHILA INFECTIONS; CHLAMYDOPHILA PNEUMONIAE; CORONARY ARTERIOSCLEROSIS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GENOTYPE; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; LOGISTIC MODELS; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; RISK FACTORS;

EID: 0037014564     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0735-1097(02)01937-X     Document Type: Article

References (47)

1. Atherosclerosis - An inflammatory disease
2. Roles of infectious agents in atherosclerosis and restenosis: An assessment of the evidence and need for future research
3. Chronic infections and coronary heart disease: Is there a link?
4. Helicobacter pylori infection and mortality from ischaemic heart disease: Negative result from a large, prospective study
5. Prospective study of potentially virulent strains of Helicobacter pylori and coronary heart disease in middle-aged men
6. Chlamydia pneumoniae IgG titres and coronary heart disease: Prospective study and meta-analysis
7. Chlamydial heat shock protein 60 localizes in human atheroma and regulates macrophage TNF-α and matrix metalloproteinase expression
8. Endothelial cytotoxicity mediated by serum antibodies to heat shock protein of Escherichia coli and-Chlamydia pneumoniae
9. Endotoxin: Possible roles in initiation and development of atherosclerosis
10. Endothelial "stunning" following a brief exposure to endotoxin: A mechanism to link infection and infarction?
11. Interactions between bacterial lipopolysaccharides and serum lipoproteins and their possible role in coronary heart disease
12. Enhanced response of blood monocytes to in vitro lipopolysaccharide-challenge in patients with recurrent unstable angina
13. Correlation between plasma endotoxin, plasma cytokines, and plasminogen activator inhibitor activities in septic patients
14. In vivo expression of proinflammatory mediators in the adult heart after endotoxin administration: The role of toll-like receptor-4
15. Endotoxins induce and interferon alpha suppresses vascular endothelial growth factor (VEGF) production in human peripheral blood mononuclear cells
16. Regulation of adhesion molecules during human endotoxemia: No acute effects of aspirin
17. Modulation of soluble phases of endothelial/leukocyte adhesion molecule-1, intercellular adhesion molecule-1, and vascular cell adhesion molecule 1 with interleukin-1 beta after experimental endotoxic challenge
18. The role of CD14 and lipopolysaccharide-binding protein (LBP) in the activation of different cell types by endotoxin
19. Role of the lipopolysaccharide (LPS)-binding protein/CD14 pathway in LPS induction of tissue factor expression in monocytic cells
20. Production of tissue factor in CD14-expressing human umbilical vein endothelial cells by lipopolysaccharide
21. Effects of endotoxin and cytokines on lipid metabolism
22. Nitric oxide: Physiology, pathology and pharmacology
23. CD14 and other recognition molecules for lipopolysaccharide: A review
24. Function of lipopolysaccharide (LPS)-binding protein (LBP) and CD14, the receptor for LPS/LBP complexes: A short review
25. Cutting edge: CD14 is an essential receptor for HSP60 activation of mononuclear cells
26. CD14: Cell surface receptor and differentiation marker
27. Evaluation of CD14 in host defence
28. Soluble CD14 activates monocytic cells independently of lipopolysaccharide
29. Endotoxin-neutralizing capacity of soluble CD14
30. Both membrane-bound and soluble forms of CD14 bind to gram-negative bacteria
31. Engagement of CD14 on monocytes inhibit the synthesis of human IgS including IgE
32. Serum levels of CD14 in neonatal sepsis by gram-positive and gram-negative bacteria
33. Increased levels of soluble CD14 in sera of periodontitis patients
34. Flow-cytometric analysis of lymphocyte subsets and mCD14 expression in patients with various periodontitis categories
35. Circulating monocytes in patients with diabetes mellitus, arterial disease, and increased CD14 expression
36. Increased expression of neutrophil and monocyte adhesion molecules LFA-1 and Mac-1 and their ligand ICAM and VLA-4 throughout the acute phase of myocardial infarction
37. C(-260)→T polymorphism in the promoter of the CD14 monocyte receptor gene as a risk factor for myocardial infarction
38. A new promoter polymorphism in the gene of lipopolysaccharide receptor CD14 is associated with expired myocardial infarction in patients with low atherosclerotic risk profile
39. Common polymorphism in the promoter of the CD14 monocyte receptor gene is associated with acute myocardial infarction in Japanese men
40. A prospective evaluation of the CD14 C(-260)→T gene polymorphism and the risk of myocardial infarction
41. Polymorphism on the promoter of lipopolysaccharide receptor CD14 and ischemic cerebrovascular disease
42. Seropositivity to chlamydial lipopoly-saccharide and Chlamydia pneumoniae, systemic inflammation and stable coronary artery disease: Negative results of a case-control study
43. Immunoradiometric assay of circulating C-reactive protein: Age-related values in the adult general population
44. A sample salting out procedure for extracting DNA from human nucleated cells
45. Increased circulating monocyte activation in patients with unstable coronary syndromes
46. Prevalence and clinical significance of silent myocardial ischemia