메뉴 건너뛰기




Volumn 182, Issue 10, 2009, Pages 6342-6352

In vivo enhancement of peptide display by MHC class II molecules with small molecule catalysts of peptide exchange

Author keywords

[No Author keywords available]

Indexed keywords

ANTIPORTER; APC PROTEIN; HLA DM ANTIGEN; HLA DR ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PEPTIDE;

EID: 70349119901     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0803464     Document Type: Article
Times cited : (31)

References (48)
  • 1
    • 33847206969 scopus 로고    scopus 로고
    • IL-17 family cytokines and the expanding diversity of effector T cell lineages
    • Weaver, C. T., R. D. Hatton, P. R. Mangan, and L. E. Harrington. 2007. IL-17 family cytokines and the expanding diversity of effector T cell lineages. Annu. Rev. Immunol. 25: 821-852.
    • (2007) Annu. Rev. Immunol. , vol.25 , pp. 821-852
    • Weaver, C.T.1    Hatton, R.D.2    Mangan, P.R.3    Harrington, L.E.4
  • 2
    • 52649167708 scopus 로고    scopus 로고
    • CD4 T cells: Fates, functions, and faults
    • Zhu, J., and W. E. Paul. 2008. CD4 T cells: fates, functions, and faults. Blood 112: 1557-1569.
    • (2008) Blood , vol.112 , pp. 1557-1569
    • Zhu, J.1    Paul, W.E.2
  • 5
    • 84969213492 scopus 로고    scopus 로고
    • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
    • Wellcome Trust Case Control Consortium.
    • Wellcome Trust Case Control Consortium. 2007. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 447: 661-678.
    • (2007) Nature , vol.447 , pp. 661-678
  • 6
    • 0033120523 scopus 로고    scopus 로고
    • Stable peptide binding to MHC class II molecule is rapid and is determined by a receptive conformation shaped by prior association with low affinity peptides
    • Natarajan, S. K., M. Assadi, and S. Sadegh-Nasseri. 1999. Stable peptide binding to MHC class II molecule is rapid and is determined by a receptive conformation shaped by prior association with low affinity peptides. J. Immunol. 162: 4030-4036.
    • (1999) J. Immunol. , vol.162 , pp. 4030-4036
    • Natarajan, S.K.1    Assadi, M.2    Sadegh-Nasseri, S.3
  • 7
    • 0027303736 scopus 로고
    • Peptide binding inhibits protein aggregation of invariant-chain free class II dimers and promotes surface expression of occupied molecules
    • Germain, R. N., and A. G. Rinker, Jr. 1993. Peptide binding inhibits protein aggregation of invariant-chain free class II dimers and promotes surface expression of occupied molecules. Nature 363: 725-728.
    • (1993) Nature , vol.363 , pp. 725-728
    • Germain, R.N.1    Rinker Jr., A.G.2
  • 9
    • 0034603779 scopus 로고    scopus 로고
    • A three-step kinetic mechanism for peptide binding to MHC class II proteins
    • DOI 10.1021/bi9923656
    • Joshi, R. V., J. A. Zarutskie, and L. J. Stern. 2000. A three-step kinetic mechanism for peptide binding to MHC class II proteins. Biochemistry 39: 3751-3762. (Pubitemid 30183857)
    • (2000) Biochemistry , vol.39 , Issue.13 , pp. 3751-3762
    • Joshi, R.V.1    Zarutskie, J.A.2    Stern, L.J.3
  • 10
    • 0026353496 scopus 로고
    • Proteolysis of the class II-associated invariant chain generates a peptide binding site in intracellular HLA-DR molecules
    • Roche, P. A., and P. Cresswell. 1991. Proteolysis of the class II-associated invariant chain generates a peptide binding site in intracellular HLA-DR molecules. Proc. Natl. Acad. Sci. USA 88: 3150-3154.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 3150-3154
    • Roche, P.A.1    Cresswell, P.2
  • 11
    • 0026440236 scopus 로고
    • HLA-DR molecules from an antigen-processing mutant cell line are associated with invariant chain peptides
    • Riberdy, J. M., J. R. Newcomb, M. J. Surman, J. A. Barbosa, and P. Cresswell. 1992. HLA-DR molecules from an antigen-processing mutant cell line are associated with invariant chain peptides. Nature 360: 474-477.
    • (1992) Nature , vol.360 , pp. 474-477
    • Riberdy, J.M.1    Newcomb, J.R.2    Surman, M.J.3    Barbosa, J.A.4    Cresswell, P.5
  • 12
    • 0026505030 scopus 로고
    • Irreversible association of peptides with class II MHC molecules in living cells
    • Lanzavecchia, A., P. A. Reid, and C. Watts. 1992. Irreversible association of peptides with class II MHC molecules in living cells. Nature 357: 249-252.
    • (1992) Nature , vol.357 , pp. 249-252
    • Lanzavecchia, A.1    Reid, P.A.2    Watts, C.3
  • 13
    • 0028350714 scopus 로고
    • An essential role for HLA-DM in antigen presentation by class II major histocompatibility molecules
    • DOI 10.1038/368551a0
    • Morris, P., J. Shaman, M. Attaya, M. Amaya, S. Goodman, C. Bergman, J. J. Monaco, and E. Mellins. 1994. An essential role for HLA-DM in antigen presentation by class II major histocompatibility molecules. Nature 368: 551-554. (Pubitemid 24118772)
    • (1994) Nature , vol.368 , Issue.6471 , pp. 551-554
    • Morris, P.1    Shaman, J.2    Attaya, M.3    Amaya, M.4    Goodman, S.5    Bergman, C.6    Monaco, J.J.7    Mellins, E.8
  • 15
    • 0028981178 scopus 로고
    • HLA-DM induces CLIP dissociation from MHC class II αβ dimers and facilitates peptide loading
    • Denzin, L. K., and P. Cresswell. 1995. HLA-DM induces CLIP dissociation from MHC class II αβ dimers and facilitates peptide loading. Cell 82: 155-165.
    • (1995) Cell , vol.82 , pp. 155-165
    • Denzin, L.K.1    Cresswell, P.2
  • 17
    • 0030458137 scopus 로고    scopus 로고
    • HLA-DM interactions with intermediates in HLA-DR maturation and a role for HLA-DM in stabilizing empty HLA-DR molecules
    • Denzin, L. K., C. Hammond, and P. Cresswell. 1996. HLA-DM interactions with intermediates in HLA-DR maturation and a role for HLA-DM in stabilizing empty HLA-DR molecules. J. Exp. Med. 184: 2153-2165.
    • (1996) J. Exp. Med. , vol.184 , pp. 2153-2165
    • Denzin, L.K.1    Hammond, C.2    Cresswell, P.3
  • 18
    • 0030978530 scopus 로고    scopus 로고
    • HLA-DM acts as a molecular chaperone and rescues empty HLA-DR molecules at lysosomal pH
    • DOI 10.1016/S1074-7613(00)80332-5
    • Kropshofer, H., S. O. Arndt, G. Moldenhauer, G. J. Hammerling, and A. B. Vogt. 1997. HLA-DM acts as a molecular chaperone and rescues empty HLA-DR molecules at lysosomal pH. Immunity 6: 293-302. (Pubitemid 27148596)
    • (1997) Immunity , vol.6 , Issue.3 , pp. 293-302
    • Kropshofer, H.1    Arndt, S.O.2    Moldenhauer, G.3    Hammerling, G.J.4    Vogt, A.B.5
  • 19
    • 0030764473 scopus 로고    scopus 로고
    • HLA-DM stabilizes empty HLA-DR molecules in a chaperone-like fashion
    • vogt, A. B., G. Moldenhauer, G. J. Hammerling, and H. Kropshofer. 1997. HLA-DM stabilizes empty HLA-DR molecules in a chaperone-like fashion. Immunol. Lett. 57: 209-211.
    • (1997) Immunol. Lett. , vol.57 , pp. 209-211
    • Vogt, A.B.1    Moldenhauer, G.2    Hammerling, G.J.3    Kropshofer, H.4
  • 22
    • 0028348369 scopus 로고
    • Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide
    • DOI 10.1038/368215a0
    • Stern, L. J., J. H. Brown, T. S. Jardetzky, J. C. Gorga, R. G. Urban, J. L. Strominger, and D. C. Wiley. 1994. Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide. Nature 368: 215-221. (Pubitemid 24108837)
    • (1994) Nature , vol.368 , Issue.6468 , pp. 215-221
    • Stern, L.J.1    Brown, J.H.2    Jardetzky, T.S.3    Gorga, J.C.4    Urban, R.G.5    Strominger, J.L.6    Wiley, D.C.7
  • 23
    • 0033713296 scopus 로고    scopus 로고
    • Determination of the HLA-DM interaction site on HLA-DR molecules
    • Doebele, R. C., R. Busch, H. M. Scott, A. Pashine, and E. D. Mellins. 2000. Determination of the HLA-DM interaction site on HLA-DR molecules. Immunity 13: 517-527.
    • (2000) Immunity , vol.13 , pp. 517-527
    • Doebele, R.C.1    Busch, R.2    Scott, H.M.3    Pashine, A.4    Mellins, E.D.5
  • 24
    • 0041429632 scopus 로고    scopus 로고
    • Interaction of HLA-DR with an acidic face of HLA-DM disrupts sequence-dependent interactions with peptides
    • DOI 10.1016/S1074-7613(03)00200-0
    • Pashine, A., R. Busch, M. P. Belmares, J. N. Munning, R. C. Doebele, M. Buckingham, G. P. Nolan, and E. D. Mellins. 2003. Interaction of HLA-DR with an acidic face of HLA-DM disrupts sequence-dependent interactions with peptides. Immunity 19: 183-192. (Pubitemid 37011333)
    • (2003) Immunity , vol.19 , Issue.2 , pp. 183-192
    • Pashine, A.1    Busch, R.2    Belmares, M.P.3    Munning, J.N.4    Doebele, R.C.5    Buckingham, M.6    Nolan, G.P.7    Mellins, E.D.8
  • 25
    • 0037099720 scopus 로고    scopus 로고
    • Identification of the lateral interaction surfaces of human histocompatibility leukocyte antigen (HLA)-DM with HLA-DR1 by formation of tethered complexes that present enhanced HLA-DM catalysis
    • DOI 10.1084/jem.20020117
    • Stratikos, E., L. Mosyak, D. M. Zaller, and D. C. Wiley. 2002. Identification of the lateral interaction surfaces of human histocompatibility leukocyte antigen (HLA)-DM with HLA-DR1 by formation of tethered complexes that present enhanced HLA-DM catalysis. J. Exp. Med. 196: 173-183. (Pubitemid 34787507)
    • (2002) Journal of Experimental Medicine , vol.196 , Issue.2 , pp. 173-183
    • Stratikos, E.1    Mosyak, L.2    Zaller, D.M.3    Wiley, D.C.4
  • 26
    • 0030723313 scopus 로고    scopus 로고
    • Interaction between HLA-DM and HLA-DR involves regions that undergo conformational changes at lysosomal pH
    • Ullrich, H. J., K. Doring, U. Gruneberg, F. Jahnig, J. Trowsdale, and S. M. van Ham. 1997. Interaction between HLA-DM and HLA-DR involves regions that undergo conformational changes at lysosomal pH. Proc. Natl. Acad. Sci. USA 94: 13163-13168.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 13163-13168
    • Ullrich, H.J.1    Doring, K.2    Gruneberg, U.3    Jahnig, F.4    Trowsdale, J.5    Van Ham, S.M.6
  • 29
    • 0034678450 scopus 로고    scopus 로고
    • Visualization of myelin basic protein (MBP) T cell epitopes in multiple sclerosis lesions using a monoclonal antibody specific for the human histocompatibility leukocyte antigen (HLA)-DR2-MBP 85-99 complex
    • DOI 10.1084/jem.191.8.1395
    • Krogsgaard, M., K. W. Wucherpfennig, B. Cannella, B. E. Hansen, A. Svejgaard, J. Pyrdol, H. Ditzel, C. Raine, J. Engberg, and L. Fugger. 2000. Visualization of myelin basic protein (MBP) T cell epitopes in multiple sclerosis lesions using a monoclonal antibody specific for the human histocompatibility leukocyte antigen (HLA)-DR2-MBP 85-99 complex. J. Exp. Med. 191: 1395-1412. (Pubitemid 30227126)
    • (2000) Journal of Experimental Medicine , vol.191 , Issue.8 , pp. 1395-1412
    • Krogsgaard, M.1    Wucherpfennig, K.W.2    Canella, B.3    Hansen, B.E.4    Svejgaard, A.5    Pyrdol, J.6    Ditzel, H.7    Raine, C.8    Engberg, J.9    Fugger, L.10
  • 31
    • 0037769037 scopus 로고    scopus 로고
    • Distinct dendritic cell populations sequentially present antigen to CD4 T cells and stimulate different aspects of cell-mediated immunity
    • Itano, A. A., S. J. McSorley, R. L. Reinhardt, B. D. Ehst, E. Ingulli, A. Y. Rudensky, and M. K. Jenkins. 2003. Distinct dendritic cell populations sequentially present antigen to CD4 T cells and stimulate different aspects of cell-mediated immunity. Immunity 19: 47-57.
    • (2003) Immunity , vol.19 , pp. 47-57
    • Itano, A.A.1    McSorley, S.J.2    Reinhardt, R.L.3    Ehst, B.D.4    Ingulli, E.5    Rudensky, A.Y.6    Jenkins, M.K.7
  • 32
    • 34247149876 scopus 로고    scopus 로고
    • The humoral immune response is initiated in lymph nodes by B cells that acquire soluble antigen directly in the follicles
    • Pape, K. A., D. M. Catron, A. A. Itano, and M. K. Jenkins. 2007. The humoral immune response is initiated in lymph nodes by B cells that acquire soluble antigen directly in the follicles. Immunity 26: 491-502.
    • (2007) Immunity , vol.26 , pp. 491-502
    • Pape, K.A.1    Catron, D.M.2    Itano, A.A.3    Jenkins, M.K.4
  • 33
    • 33646917482 scopus 로고    scopus 로고
    • Anatomy and nomenclature of murine lymph nodes: Descriptive study and nomenclatory standardization in BALB/cAnNCrl mice
    • DOI 10.1016/j.jim.2006.01.022, PII S0022175906000640
    • Van den Broeck, W., A. Derore, and P. Simoens. 2006. Anatomy and nomen-clature of murine lymph nodes: descriptive study and nomenclatory standardization in BALB/cAnNCrl mice. J. Immunol. Methods 312: 12-19. (Pubitemid 43795993)
    • (2006) Journal of Immunological Methods , vol.312 , Issue.1-2 , pp. 12-19
    • Van Den Broeck, W.1    Derore, A.2    Simoens, P.3
  • 35
    • 0028120895 scopus 로고
    • Structural requirements for binding of an immunodominant myelin basic protein peptide to DR2 isotypes and for its recognition by human T cell clones
    • Wucherpfennig, K. W., A. Sette, S. Southwood, C. Oseroff, M. Matsui, J. L. Strominger, and D. A. Hafler. 1994. Structural requirements for binding of an immunodominant myelin basic protein peptide to DR2 isotypes and for its recognition by human T cell clones. J. Exp. Med. 179: 279-290.
    • (1994) J. Exp. Med. , vol.179 , pp. 279-290
    • Wucherpfennig, K.W.1    Sette, A.2    Southwood, S.3    Oseroff, C.4    Matsui, M.5    Strominger, J.L.6    Hafler, D.A.7
  • 36
    • 10944263783 scopus 로고    scopus 로고
    • "Chemical analogues" of HLA-DM can induce a peptide-receptive state in HLA-DR molecules
    • DOI 10.1074/jbc.M407598200
    • Marin-Esteban, V., K. Falk, and O. Rotzschke. 2004. "Chemical analogues" of HLA-DM can induce a peptide-receptive state in HLA-DR molecules. J. Biol. Chem. 279: 50684-50690. (Pubitemid 40017805)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.49 , pp. 50684-50690
    • Marin-Esteban, V.1    Falk, K.2    Rotzschke, O.3
  • 38
    • 0032547858 scopus 로고    scopus 로고
    • Crystal structure of HLA-DR2 (DRA*0101, DRB1*1501) Complexed with a peptide from human myelin basic protein
    • DOI 10.1084/jem.188.8.1511
    • Smith, K. J., J. Pyrdol, L. Gauthier, D. C. Wiley, and K. W. Wucherpfennig. 1998. Crystal structure of HLA-DR2 (DRA*0101, DRB1*1501) complexed with a peptide from human myelin basic protein. J. Exp. Med. 188: 1511-1520. (Pubitemid 28489588)
    • (1998) Journal of Experimental Medicine , vol.188 , Issue.8 , pp. 1511-1520
    • Smith, K.J.1    Pyrdol, J.2    Gauthier, L.3    Wiley, D.C.4    Wucherpfennig, K.W.5
  • 41
    • 0021956416 scopus 로고
    • Antigen-specific interaction between T and B cells
    • Lanzavecchia, A. 1985. Antigen-specific interaction between T and B cells. Nature 314: 537-539.
    • (1985) Nature , vol.314 , pp. 537-539
    • Lanzavecchia, A.1
  • 42
    • 0022965606 scopus 로고
    • Antigen presentation by B lymphocytes: A critical step in T-B collaboration
    • Lanzavecchia, A. 1986. Antigen presentation by B lymphocytes: a critical step in T-B collaboration. Curr. Top. Microbiol. Immunol. 130: 65-78.
    • (1986) Curr. Top. Microbiol. Immunol. , vol.130 , pp. 65-78
    • Lanzavecchia, A.1
  • 43
    • 33748475526 scopus 로고    scopus 로고
    • Enhancing immunogenicity by limiting susceptibility to lysosomal proteolysis
    • DOI 10.1084/jem.20052442
    • Delamarre, L., R. Couture, I. Mellman, and E. S. Trombetta. 2006. Enhancing immunogenicity by limiting susceptibility to lysosomal proteolysis. J. Exp. Med. 203: 2049-2055. (Pubitemid 44352226)
    • (2006) Journal of Experimental Medicine , vol.203 , Issue.9 , pp. 2049-2055
    • Delamarre, L.1    Couture, R.2    Mellman, I.3    Trombetta, E.S.4
  • 46
    • 0036838687 scopus 로고    scopus 로고
    • Structural factors contributing to DM susceptibility of MHC class II/peptide complexes
    • Belmares, M. P., R. Busch, K. W. Wucherpfennig, H. M. McConnell, and E. D. Mellins. 2002. Structural factors contributing to DM susceptibility of MHC class II/peptide complexes. J. Immunol. 169: 5109-5117.
    • (2002) J. Immunol. , vol.169 , pp. 5109-5117
    • Belmares, M.P.1    Busch, R.2    Wucherpfennig, K.W.3    McConnell, H.M.4    Mellins, E.D.5
  • 48
    • 0029082566 scopus 로고
    • Copolymer 1 reduces relapse rate and improves disability in relapsing-remitting multiple sclerosis: Results of a phase III multicenter, double-blind placebo-controlled trial: The Copolymer 1 Multiple Sclerosis Study Group
    • Johnson, K. P., B. R. Brooks, J. A. Cohen, C. C. Ford, J. Goldstein, R. P. Lisak, L. W. Myers, H. S. Panitch, J. W. Rose, and R. B. Schiffer. 1995. Copolymer 1 reduces relapse rate and improves disability in relapsing-remitting multiple sclerosis: results of a phase III multicenter, double-blind placebo-controlled trial: The Copolymer 1 Multiple Sclerosis Study Group. Neurology 45: 1268-1276.
    • (1995) Neurology , vol.45 , pp. 1268-1276
    • Johnson, K.P.1    Brooks, B.R.2    Cohen, J.A.3    Ford, C.C.4    Goldstein, J.5    Lisak, R.P.6    Myers, L.W.7    Panitch, H.S.8    Rose, J.W.9    Schiffer, R.B.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.