Causes of oxidative stress in the pre- and perinatal period

Biology of the Neonate

Volumn 81, Issue 3, 2002, Pages 146-157

  Gitto, Eloisa ^a,b   Reiter, Russel J ^a   Karbownik, Malgorzata ^c   Tan, Dun Xian ^a   Gitto, Placido ^b   Barberi, Salvatore ^b   Barberi, Ignazio ^b  

^a Mays Cancer Center at UT Health San Antonio   (United States)

^b UNIVERSITY OF MESSINA   (Italy)

^c MEDICAL UNIVERSITY OF LODZ   (Poland)

Author keywords

Free radicals; Oxidative stress; Perinatal asphyxia; Preeclampsia; Pregnancy; Toxic substances

Indexed keywords

ALLOPURINOL; ANTIOXIDANT; DEFEROXAMINE; FREE RADICAL; GLUTATHIONE PEROXIDASE; HEMOGLOBIN; LIPID PEROXIDE; MELATONIN; METHEMOGLOBIN; NITROGEN DERIVATIVE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; TOXIC SUBSTANCE;

ANTIOXIDANT ACTIVITY; CELL DAMAGE; HUMAN; LIPID PEROXIDATION; MOTHER FETUS RELATIONSHIP; NEWBORN MORTALITY; OXIDATIVE STRESS; OXYGEN CONSUMPTION; PATHOGENESIS; PERINATAL ASPHYXIA; PERINATAL PERIOD; PREECLAMPSIA; PREGNANCY; PREMATURITY; PRENATAL PERIOD; PRIORITY JOURNAL; REVIEW; RISK FACTOR; SMOKING;

ANTIOXIDANTS; ASPHYXIA NEONATORUM; FEMALE; FETUS; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; NITRIC OXIDE; NITRITES; OXIDATIVE STRESS; PRE-ECLAMPSIA; PREGNANCY;

EID: 0036214829     PISSN: 00063126     EISSN: None     Source Type: Journal    
DOI: 10.1159/000051527     Document Type: Review

References (149)

1. Free radicals, antioxidants and human disease: Curiosity, cause, or consequence?
2. Oxygen toxicity: A radical explanation
3. Oxygen radicals as key mediators in neurological disease: Fact or fiction?
4. Mechanisms of tissue injury by oxygen radicals: Lmplications for neonatal disease
5. Oxygen radical-induced single-strand DNA breaks and repair of the damage in a cell-free system
6. The variability of cardiopulmonary adaptation to pregnancy at rest and during exercise
7. Role of free radicals and catalytic metal ions in human disease: An overview
8. Studies on lipoperoxide of normal pregnant women and of patients with toxaemia of pregnancy
9. Free-radical oxidation (peroxidation) products in plasma in normal and abnormal pregnancy
10. Maternal levels of prostacyclin, thromboxane, vitamin E, and lipid peroxides throughout normal pregnancy
11. Antioxidant systems in normal pregnancy and in pregnancy-induced hypertension
12. Serum antioxidant activity in normal and abnormal subjects
13. Sera antioxidant activity in uncomplicated and preeclamptic pregnancies
14. Changes of lipid peroxidation and superoxide dismutase activity in the human placenta
15. Changes in the levels of lipoperoxide and antioxidant factors in human placenta during gestation
16. Antioxidant systems in normal pregnancy and in pregnancy hypertension
17. Secretion of lipid peroxides by the human placenta
18. Mechanism of action of biological antioxidants
19. Selenium and sulfur in antioxidant protective systems: Relationship with vitamin E and malaria
20. Secretion of lipid peroxides by the human placenta
21. Antioxidant activities and mRNA expression of superoxide dismutase, catalase, and glutathione peroxidase in normal and preeclamptic placentas
22. Properties of enzymes. I. Study of superoxide dismutase activity change in human placenta of different ages
23. Glutathione S-transferase (transferase p) from human placenta is identical or closely related to glutathione S-transferase (transferase P) from erythrocytes
24. Variations in expression of copper/zinc superoxide dismutase in villous trophoblast of the human placenta with gestational age
25. Hypertension in pregnancy
26. Morphological changes in the uteroplacental bed in pregnancy hypertension
27. Inadequate maternal vascular response to placentation in pregnancies complicated by preeclampsia and by small-for-gestational age infants
28. Lipid peroxide levels and lipid content of serum lipoprotein fractions of pregnant subjects with or without pre-eclampsia
29. The imbalance between thromboxane and prostacyclin in preeclampsia is associated with an imbalance between lipid peroxides and vitamin E in maternal blood
30. Fasting serum triglycerides, free fatty acids, and malondialdehyde are increased in preeclampsia, are positively correlated, and decrease within 48 hours post partum
31. Serum lipoproteins, insulin, and urinary prostanoid metabolites in normal and hypertensive pregnant women
32. Does free fatty acid infusion impair insulin action also through an increase in oxidative stress?
33. The origin of increased serum iron in pregnancy-induced hypertension
34. Increased levels of carboxyhemoglobin and serum iron as an indicator of increased red cell turnover in preeclampsia
35. Role of free radicals and catalytic metal ions in human disease: An overview
36. Relationship between elevated lipid peroxides, vitamin E deficiency and hypertension in preeclampsia
37. Preeclampsia and antioxidant nutrients: Decreased plasma levels of reduced ascorbic acid, α-tocopherol, and beta-carotene in women with preeclampsia
38. Deficient glutathione peroxidase activity in preeclampsia is associated with increased placental production of thromboxane and lipid peroxides
39. Imbalance between lipid peroxidation and antioxidant status in preeclampsia
40. Subcellular localization and characterization of nitric oxide synthase(s) in endothelial cells: Physiological implications
41. Evidence for peroxynitrite formation in the vasculature of women with preeclampsia
42. Nitric oxide, superoxide, and peroxynitrite: The good, the bad, and the ugly
43. Nitrotyrosine residues in placenta: Evidence of peroxynitrite formation and action
44. What nitrates tyrosine? Is nitrotyrosine specific as a biomarker of peroxynitrite formation in vivo?
45. Extensive nitration of protein tyrosines observed in human atherosclerosis detected by immunohistochemistry
46. Immunohistochemically detected protein nitration indicates sites of renal nitric oxide release in Goldblatt hypertension
47. The balance between nitric oxide and superoxide determines apoptotic and necrotic death of rat mesangial cells
48. Peroxynitrite, the coupling product of nitric oxide and superoxide, activates prostaglandin biosynthesis
49. Cyclooxygenase-dependent vasoconstriction alters vascular function in the vitamin E-deprived rat
50. Impaired endothelium-dependent relaxations in hypertensive resistance arteries involve cyclo-oxygenase pathway
51. Maternal-placental interactions of oxidative stress and antioxidants in preeclampsia
52. Experimental study on lipid peroxide formation and tumor-promoting effects of nitrogen dioxide and ozone
53. Nitric oxide as a mediator of superoxide-dependent injury
54. Induction of lipid peroxidation of pulmonary surfactant by plasma of preterm babies
55. Exposure to oxidized nitrogen: Lipid peroxidation and neonatal health risk
56. Maternal exposure to exogenous nitrogen compounds and complications of pregnancy
57. Complications of pregnancy in relation to maternal lipid peroxides, glutathione, and exposure to metals
58. Environmental pollutants in relation to complications of pregnancy
59. Ethane expiration among smokers and non smokers
60. Furosemide and vitamin E: Two problems in neonatology
61. Cigarette smoking is pro-oxidant in pregnant women regardless of antioxidant nutrient intake
62. Prooxidant effects of maternal smoking and formula in newborn infants
63. Vitamin E
64. Cigarette smoking-nutritional implications
65. Prenatal development of lung antioxidant enzymes in four species
66. The effects of fish oil on triglycerides, cholesterol, fibrinogen and malondialdehyde in humans supplemented with vitamin E
67. Effects of maternal vitamin E and selenium status during the prenatal period on age-related changes in heart, lung and liver microsomal lipid peroxidation in rat pups
68. Vitamin E and haemolytic anaemia in premature infants
69. Problemática nutritional del fumador: Papel de la dieta en la aparición y progreso de cataratas
70. Plasma vitamins A and E and red blood cell fatty acid profile in newborns and their mothers
71. Influence of smoking on vitamin E status during the third trimester of pregnancy and on breast-milk tocopherol concentrations in Spanish women
72. The incidence and severity of post-asphyxial encephalopathy in full-term infants
73. Use and abuse of the Apgar score
74. Birth asphyxia and the neonatal brain: What do we know and when do we know it?
75. Predictors of neonatal encephalopathy in full term infants
76. Carbohydrate and energy metabolism during the evolution of hypoxic-ischemic brain damage in the immature rat
77. Cerebral energy metabolism during hypoxia-ischemia and early recovery in immature rats
78. Cerebral energy metabolism in immature and mature guinea pig fetuses during acute asphyxia
79. Extension of the 2-deoxyglucose method to the fetus in utero: Theory and normal values for cerebral glucose consumption in fetal guinea pigs
80. Nature, time-course and extent of cerebral edema in perinatal hypoxic-ischemic brain damage
81. Hypoxic brain and heart injury thresholds in piglets
82. Brain cortical fatty acids and phospholipids during and following complete and severe incomplete ischemia
83. Phosphatidylinositol metabolism during in vitro hypoxia
84. Perinatal brain injury
85. Free radicals and brain damage in the newborn
86. Perinatal brain injury
87. Oxidative stress as a mediator of apoptosis
88. Mechanism of cell death in hypoxia-reoxygenation injury
89. Global ischemia can cause DNA fragmentation indicative of apoptosis in rat brain
90. Oxygen radical production and thiol depletion are required for Ca2+ mediated endogenous endonuclease activation in apoptotic thymocytes
91. A model for p53-induced apoptosis
92. Role of free radicals and catalytic ions in human disease: An overview
93. Hypoxia-induced free iron released in the red cells of newborn infants
94. Iron release and membrane damage in erythrocytes exposed to oxidizing agents, phenylhydrazine, divicine and isouramil
95. Superoxide anion release by polymorphonuclear leukocytes in whole blood of newborns and mothers during the peripartal period
96. Oxygen toxicity in the neonatal period
97. Intraerythrocyte non protein-bound iron and plasma malondialdehyde in the hypoxic newborn
98. The importance of superoxide in nitric-oxide-dependent toxicity: Evidence for peroxynitrite-mediated injury
99. DNA damage induced by peroxinitrite: Subsequent biological effects
100. The role of peroxynitrite in nitric oxide-mediated toxicity
101. TNF-alpha induces peroxynitrite-mediated depletion of lung endothelial glutathione via protein kinase C
102. Oxidative DNA damage induced by simultaneous generation of nitric oxide and superoxide
103. DNA damage and oxidation of thiol peroxynitrite causes in rat thymocytes
104. Endothelial dysfunction in endotoxic shock: Importance of the activation of poly (ADP ribose) synthetase (PARS) by peroxynitrite
105. Oxidative stress causes vascular dysfunction in the placenta
106. Oxidative stress, brain white matter damage and intrauterine asphyxia in fetal lambs
107. Increased injury following intermittent fetal hypoxia-reoxygenation is associated with increased free radical production in fetal rabbit brain
108. Direct measurement of oxygen free radicals during in utero hypoxia in the fetal guinea pig brain
109. Lipid free radical generation and brain cell membrane alteration following nitric oxide synthase inhibition during cerebral hypoxia in the newborn piglet
110. Glutathione levels in liver and brain of newborn rats: Investigations of the influence of hypoxia and reoxidation on lipid peroxidation
111. Direct measurement of free radicals in the neonatal mouse brain subjected to hypoxia: An electron spin resonance spectroscopic study
112. Erythrocyte cupric/zinc superoxide dismutase exhibits reduced activity in preterm and low-birth-weight infants at birth
113. Selenium and vitamin E in cord blood from preterm and full term infants
114. Bilirubin and ascorbate: Antioxidant activity in neonatal plasma
115. Lipid peroxidation as a measure of oxygen free radical damage in the very low birth weight infant
116. Bleomycin-detectable iron in the plasma of premature and full-term neonates
117. Oxygen-derived free radicals in post-ischemic tissue injury
118. Cellular mechanisms of cerebral injury in the developing brain
119. High total antioxidant activity and uric acid in tracheobronchial aspirate fluid of preterm infants during oxidative stress: An adaptive response to hyperoxia?
120. Serum malondialdehyde concentration as a measure of oxygen free radical damage in preterm infants
121. Plasma 3-nitrotyrosine is elevated in premature infants who develop bronchopulmonary dysplasia
122. Chronic lung disease: The role of oxidative stress
123. Hyperoxia causes an increase in antioxidant enzyme activity in adult and fetal rat type II pneumocytes
124. Lung injury and surfactant metabolism after hyperventilation of premature lambs
125. Different ventilation strategies affect lung function but do not increase tumor necrosis factor-alpha and prostacyclin production in lavaged rat lungs in vivo
126. Mechanism of ventilation-induced lung injury: Physiological rationale to prevent it
127. Polyethylene glycol-conjugated superoxide dismutase and catalase reduce ischemic brain injury
128. The role of oxygen free radicals in postasphyxia cerebral hypoperfusion in newborn lambs
129. Oxidative stress during post-hypoxici-schemic reperfusion in the newborn lamb: The effect of nitric oxide synthesis inhibition
130. Effect of desferoxamine and allopurinol on non-protein iron concentrations in plasma and cortical brain tissue of newborn lambs following hypoxia-ischemia
131. +-ATPase activity of cortical brain cell membrane during early reperfusion after hypoxia-ischemia in newborn lambs
132. A novel melatonin metabolite, cyclic 3-hydroxymelatonin: A biomarker of melatonin interaction with hydroxyl radicals
133. Pharmacological actions of melatonin in free radical pathophysiology
134. Actions of melatonin in the reduction of oxidative stress: A review
135. Melatonin: Lowering the high price of free radicals
136. Melatonin directly scavenges hydrogen peroxide: A potentially new metabolic pathway of melatonin biotransformation
137. Protective effect of melatonin on cellular energy depletion mediated by peroxynitrite and poly (ADP-ribose) synthetase activation in a non-septic shock model induced by zymosan in the rat
138. Significance of melatonin in antioxidative defence system: Reactions and products
139. Melatonin induces γ-glutamylcysteine synthetase mediated by activator protein-1 in human vascular endothelial cells
140. Melatonin administration prevents lipopolysaccharide-induced oxidative damage in phenobarbital-treated rats
141. Effects of melatonin treatment in septic newborns
142. Increased levels of malondialdehyde and nitrite/nitrates in the blood of asphyxiated newborns: Reduction by melatonin
143. Oxidative stress in newborn infants with and without asphyxia as measured by plasma antioxidants and free fatty acids
144. Oxidative stress during post-hypoxic-ischemic reperfusion in the newborn lamb: The effect of nitric oxide synthesis inhibition
145. Melatonin inhibits the vasorelaxant action of peroxynitrite in human umbilical artery
146. Melatonin suppresses lysophosphatidylcholine enhancement of serotonin-induced vasoconstriction in the human umbilical artery