Scorpion venom (Odontobuthus doriae) induces apoptosis by depolarization of mitochondria and reduces S-phase population in human breast cancer cells (MCF-7)

Toxicology in Vitro

Volumn 25, Issue 8, 2011, Pages 1748-1756

  Zargan, Jamil ^a   Umar, Sadiq ^a   Sajad, Mir ^a   Naime, M ^a   Ali, Shakir ^a   Khan, Haider A ^a  

^a HAMDARD UNIVERSITY   (India)

Author keywords

Apoptosis; BrdU; Caspase 3; MCF 7; Mitochondrial membrane potential; Odontobuthus doriae; Proliferation; Scorpion venom

Indexed keywords

BROXURIDINE; CASPASE 3; CATALASE; GLUTATHIONE; LACTATE DEHYDROGENASE; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; SCORPION VENOM;

ANIMAL CELL; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL; CELL CYCLE ARREST; CELL CYCLE S PHASE; CELL PROLIFERATION; CELL STRAIN MCF 7; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEPOLARIZATION; DNA FRAGMENTATION; DNA SYNTHESIS INHIBITION; DRUG CYTOTOXICITY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME RELEASE; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; NONHUMAN; ODONTOBUTHUS DORIAE; POISONOUS SCORPION;

APOPTOSIS; BREAST NEOPLASMS; CASPASE 3; CATALASE; CELL LINE, TUMOR; CELL SURVIVAL; DNA FRAGMENTATION; FEMALE; GLUTATHIONE; HUMANS; L-LACTATE DEHYDROGENASE; MEMBRANE POTENTIAL, MITOCHONDRIAL; REACTIVE NITROGEN SPECIES; S PHASE; SCORPION VENOMS;

ODONTOBUTHUS DORIAE; SCORPIONES;

EID: 82655173834     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2011.09.002     Document Type: Article

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