The binding of BmK abT, a unique neurotoxin, to mammal brain and insect Na+ channels using biosensor

European Journal of Pharmacology

Volumn 454, Issue 1, 2002, Pages 25-30

  Ji, Yong Hua ^a   Wang, Wei Xi ^a   Wang, Qiong ^b   Huang, Yong Ping ^c  

^a Shanghai Jiao Tong University Affiliated Sixth People s Hospital   (China)

^b INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

^c INSTITUTE OF PLANT PHYSIOLOGY AND ECOLOGY   (China)

Author keywords

BIAcore assay; BmK abT; Na+ channel; Receptor binding site; Scorpion neurotoxin

Indexed keywords

NEUROTOXIN BMK 1; NEUROTOXIN BMK ABT; NEUROTOXIN BMK AS; NEUROTOXIN BMK IT2; SCORPION VENOM; SODIUM CHANNEL; UNCLASSIFIED DRUG; VERATRIDINE; ABT, BUTHUS MARTENSI KARSCH; NEUROMUSCULAR DEPOLARIZING AGENT; NEUROTOXIN;

ANIMAL TISSUE; ARTICLE; BINDING COMPETITION; BINDING KINETICS; BINDING SITE; BIOSENSOR; BRAIN SYNAPTOSOME; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG RECEPTOR BINDING; INSECT; MALE; MAMMAL; MEMBRANE POTENTIAL; NERVE CORD; NONHUMAN; PRIORITY JOURNAL; RAT; ANIMAL; BRAIN; DOSE RESPONSE; GANGLION; GENETIC PROCEDURES; IN VITRO STUDY; KINETICS; METABOLISM; MOTH; PROTEIN BINDING; SYNAPTOSOME; ULTRASTRUCTURE; WISTAR RAT;

ANIMALS; BINDING, COMPETITIVE; BIOSENSING TECHNIQUES; BRAIN; DOSE-RESPONSE RELATIONSHIP, DRUG; GANGLIA, INVERTEBRATE; KINETICS; MALE; MOTHS; NEUROMUSCULAR DEPOLARIZING AGENTS; NEUROTOXINS; PROTEIN BINDING; RATS; RATS, WISTAR; SCORPION VENOMS; SODIUM CHANNELS; SYNAPTOSOMES; VERATRIDINE;

EID: 0036842070     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(02)02363-4     Document Type: Article

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