A shift in the collagen V antigenic epitope leads to T helper phenotype switch and immune response to self-antigen leading to chronic lung allograft rejection

Clinical and Experimental Immunology

Volumn 167, Issue 1, 2012, Pages 158-168

  Tiriveedhi, V ^a   Angaswamy, N ^a   Brand, D ^b   Weber, J ^a   Gelman, A G ^a   Hachem, R ^a   Trulock, E P ^a   Meyers, B ^a   Patterson, G ^a   Mohanakumar, T ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Antibody; Autoimmunity; Epitopes; HLA; Lung transplant

Indexed keywords

COLLAGEN TYPE 5; EPITOPE; GAMMA INTERFERON; HLA DR4 ANTIGEN; HLA DR7 ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 17; MATRIX METALLOPROTEINASE; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2;

ADULT; ALPHA CHAIN; ARTICLE; BRONCHIOLITIS OBLITERANS; CHRONIC GRAFT REJECTION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HELPER CELL; HUMAN; HUMAN TISSUE; IMMUNE RESPONSE; LUNG BIOPSY; LUNG GRAFT REJECTION; MALE; PHENOTYPE; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE;

ADULT; AMINO ACID SEQUENCE; AUTOANTIGENS; BRONCHIOLITIS OBLITERANS; COLLAGEN TYPE I; COLLAGEN TYPE V; DNA METHYLATION; ENZYME ACTIVATION; FEMALE; FOLLOW-UP STUDIES; FORKHEAD TRANSCRIPTION FACTORS; GRAFT REJECTION; HUMANS; IMMUNODOMINANT EPITOPES; IMMUNOPHENOTYPING; IMMUNOSUPPRESSIVE AGENTS; INTERFERON-GAMMA; INTERLEUKIN-17; ISOANTIGENS; LUNG; LUNG TRANSPLANTATION; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MIDDLE AGED; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; SELF TOLERANCE; T-LYMPHOCYTES, HELPER-INDUCER; TRANSPLANTATION TOLERANCE;

EID: 82655171668     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2011.04486.x     Document Type: Article

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