Development of melanoma-targeted polymer micelles by conjugation of a melanocortin 1 receptor (MC1R) specific ligand

Journal of Medicinal Chemistry

Volumn 54, Issue 23, 2011, Pages 8078-8084

  Barkey, Natalie M ^a   Tafreshi, Narges K ^a   Josan, Jatinder S ^b   De Silva, Channa R ^c   Sill, Kevin N ^d   Hruby, Victor J ^b,e   Gillies, Robert J ^a   Morse, David L ^a   Vagner, Josef ^b  

^a H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF ARIZONA   (United States)

^c WESTERN CAROLINA UNIVERSITY   (United States)

^d Intezyne Technologies Inc   (United States)

^e University of Arizona   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYNE; ANTINEOPLASTIC AGENT; COPPER; MELANOCORTIN 1 RECEPTOR; MELANOCORTIN 4 RECEPTOR; MELANOCORTIN 5 RECEPTOR; MELANOMA TARGETED POLYMER; POLYMER; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CANCER CELL; CLICK CHEMISTRY; CONTROLLED STUDY; DRUG CONJUGATION; DRUG DESIGN; DRUG FORMULATION; DRUG SYNTHESIS; DRUG TARGETING; HUMAN; HUMAN CELL; MELANOMA; MICELLE;

ALKYNES; ANTINEOPLASTIC AGENTS; AZIDES; BINDING, COMPETITIVE; CLICK CHEMISTRY; DRUG SCREENING ASSAYS, ANTITUMOR; HCT116 CELLS; HEK293 CELLS; HUMANS; LIGANDS; MELANOMA; MICELLES; OLIGOPEPTIDES; POLYETHYLENE GLYCOLS; PROTEINS; RECEPTOR, MELANOCORTIN, TYPE 1; RECEPTOR, MELANOCORTIN, TYPE 4; RECEPTORS, MELANOCORTIN; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 82555204257     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm201226w     Document Type: Article

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