Molecular analysis of melanoma precursor lesions

Cell Growth and Differentiation

Volumn 7, Issue 12, 1996, Pages 1733-1740

  Wang, Yiping ^a   Rao, Uma ^a   Mascari, Ruth ^a   Richards, Thomas J ^a   Panson, Armand J ^a   Edington, Howard D ^b   Shipe Spotloe, Janice M ^a   Donnelly, Sandra S ^a   Kirkwood, John M ^a   Becker, Dorothea ^a,b  

^a UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; CELL ADHESION MOLECULE; EPIDERMAL GROWTH FACTOR RECEPTOR; FIBROBLAST GROWTH FACTOR RECEPTOR; INTEGRIN; TRANSFORMING GROWTH FACTOR ALPHA;

ARTICLE; CELL TRANSFORMATION; CLINICAL ARTICLE; CLINICAL PROTOCOL; CONTROLLED STUDY; DERMOEPIDERMAL JUNCTION; DYSPLASTIC NEVUS; GENE ACTIVITY; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IN SITU HYBRIDIZATION; MELANOCYTIC NEVUS; MELANOMA; MOLECULAR BIOLOGY; PRECANCER; PRIORITY JOURNAL;

ANTIGENS, CD; ANTIGENS, CD146; CELL ADHESION MOLECULES; DYSPLASTIC NEVUS SYNDROME; FIBROBLAST GROWTH FACTOR 2; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MELANOMA; MEMBRANE GLYCOPROTEINS; NEURAL CELL ADHESION MOLECULES; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTORS, FIBROBLAST GROWTH FACTOR; RECEPTORS, VITRONECTIN; RNA, MESSENGER; SKIN NEOPLASMS; TRANSFORMING GROWTH FACTOR ALPHA; TUMOR MARKERS, BIOLOGICAL;

EID: 10544251060     PISSN: 10449523     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Clark, W. H., Jr., Reimer, R. R., Greene, M., Ainsworth, A. M., and Mastrangelo, M. J. Origin of familial malignant melanomas from heritable melanocytic lesions. "The B-K mole syndrome". Arch. Dermatol., 114: 732-738, 1978.
2. Reimer, R. R., Clark, W. H., Jr., Greene, M. H., Ainsworth, A. M., and Fraumeni, J. F., Jr. Precursor lesions in familial melanoma: a new genetic preneoplastic syndrome. J. Am. Med. Assoc., 239: 744-746, 1978.
3. Nordlund, J. J., Kirkwood, J., Forget, B. M., Schreibner, A., Albert, D. M., Lerner, A. B., and Milton, G. W. Clinically atypical nevi in patients with melanoma and in control subjects: a clinical and demographic study. Cancer Res., 45: 1855-1861, 1985.
4. Clark, W. H. Tumor progression and the nature of cancer. Br. J. Cancer, 64: 631-644, 1991.
5. Greene, M., Clark, W. H., Jr., Tucker, M. A., Kraemer, K. H., Elder, D. E., and Fraser, M. C. High risk of malignant melanoma in melanoma-prone families with dysplastic nevi. Ann. Intern. Med., 102: 458-465, 1985.
6. Carey, W. P., Jr., Thompson, C. J., Synnestvedt, M., Guerry, D., IV, Halpern, A., Schultz, D., Elder, D. E., and Guerry, D. Dysplastic nevi as a melanoma risk factor in patients with familial melanoma. Cancer (Phila.), 74: 3118-3125, 1994.
7. Elder, D. E., Goldman, L. I., Goldman, S. C., Greene, M. H., and Clark, W. H., Jr. Dysplastic nevus syndrome: a phenotypic association of sporadic cutaneous melanoma. Cancer (Phila.), 46: 1787-1794, 1980.
8. Rhodes, A. R., Harrist, T. J., Day, C. L., Mihm, M. C., Jr., Fitzpatrick, T. B., and Sober, A. J. Dysplastic melanocytic nevi in histologic association with 234 primary cutaneous melanomas. J. Am. Acad. Dermatol., 9: 563-574, 1983.
9. Titus-Ernsthoff, L., Duray, P. H., Ernsthoff, M. S., Bamhill, R. L., Horn, P. L., and Kirkwood, J. M. Dysplastic nevi in association with multiple primary melanomas. Cancer Res., 48: 1016-1018, 1988.
10. Black, W. C., and Hunt, W. C. Histologic correlations with the clinical diagnosis of dysplastic nevus. Am. J. Surg. Pathol., 14: 44-52, 1990.
11. Elder, D. E., Clark, W. H., Jr., Elenitsas, R., Guerry, D., IV, and Halpem, A. The early and intermediate lesions of tumor progression in the melanocytic system: common acquired nevi and atypical (dysplastic) nevi. Semin. Diagn. Pathol., 10: 18-35, 1993.
12. Herlyn, M. Molecular and cellular biology of melanoma. Austin, TX: R. G. Landes Co., 1994.
13. Halaban, R. Langdon, N., Birchall, C., Cuono, C., Baird, A., Scott, G., Moellmann, G., and McGuire, J. Basic fibroblast growth factor from human keratinoeytes is a natural mitogen for melanocytes. J. Cell Biol., 107: 1611-1619, 1988.
14. Becker, D., Meier, C. B., and Herlyn, M. Proliferation of human malignant melanomas is inhibited by antisense oligodeoxynucleotides targeted against basic fibroblast growth factor. EMBO J., 8: 3685-3691, 1989.
15. Becker, D., Lee, P. L., Rodeck, U., and Herlyn, M. Inhibition of the fibroblast growth factor receptor 1 (FGFR-1) gene in human melanocytes and malignant melanomas leads to inhibition of proliferation and signs indicative of differentiation. Oncogene, 7: 2303-2313, 1992.
16. Derynck, R., Goeddel, D. V., Ullrich, A., Gutterman, J. U., Williams, R. D., Bringman, T. S., and Berger, W. H. Synthesis of messenger mRNAs for transforming growth factor α and β and the epidermal growth factor receptor by human tumors. Cancer Res., 47: 702-712, 1987.
17. Elder, D. E., Rodeck, U., Thurin, J., Cardillo, F., Clark, W. H., Jr., Stewart, R., and Herlyn, M. Antigenic profile of tumor progression in human melanocytic nevi and melanomas. Cancer Res., 49: 5091-5096, 1989.
18. Lehmann, J. M., Riethmuller, G., and Johnson, J. P. MUC18, a marker of tumor progression in human melanoma, shows sequence similarity to the neural cell adhesion molecules of the immunoglobulin superfamily. Proc. Natl. Acad. Sci. USA, 86: 9891-9895, 1989.
19. Cheresh, D. A. Human endothelial cells synthesize and express an Arg-Gly-Asp-directed adhesion receptor involved in attachment to fibrinogen and von Willebrand factor. Proc. Natl. Acad. Sci. USA, 84: 6471-6475, 1987.
20. Cheresh, D. A., and Spiro, R. C. Biosynthetic and functional properties of Arg-Gly-Asp-directed receptor involved in human melanoma cell attachment to vitronectin, fibrinogen and von Willebrand factor. J. Biol. Chem., 262: 17703-17711, 1987.
21. Albelda, S. M., Mette, S. A., Elder, D. E., Stewart, R., Damjanovich, L., Herlyn, M., and Buck, C. A. Integrin distribution in malignant melanoma: association of the β3 subunit with tumor progression. Cancer Res., 50: 6757-6764, 1990.
22. Cheresh, D. A. Structure, function and biological properties at integrin ανβ3 on human melanoma cells. Cancer Metastasis Rev., 10: 3-10, 1991.
23. Rodeck, U., Melber, K., Kath, R., Menssen, H. D., Varello, M., Atkinson, B., and Herlyn, M. Constitutive expression of multiple growth factor genes by melanoma cells but not normal melanocytes. J. Invest. Dermatol., 97: 20-26, 1991.
24. Halaban, R., Kwon, B. S., Ghosh, S., Delli, B. P., and Baird, A. bFGF as an autocrine growth factor for human melanomas. Oncogene Res., 3: 177-186, 1988.
25. Reed, J. A., McNutt, N. S., and Albino, A. P. Differential expression of basic fibroblast growth factor (bFGF) in melanocytic lesions demonstrated by in situ hybridization. Am. J. Pathol., 144: 329-336, 1994.
26. Brooks, P. C., Clark, R. A. F., and Cheresh, D. A. Requirement of vascular integrin ανβ3 for angiogenesis. Science (Washington DC), 264: 569-571, 1994.
27. Montgomery, A. M., Reisfeld, R. A., and Cheresh, D. A. Integrin ανβ3 rescues melanoma cells from apoptosis in three-dimensional dermal collagen. Proc. Natl. Acad. Sci. USA, 91: 8856-8860, 1994.
28. Abraham, J. A., Whang, J. L., Tumolo, A., Mergia, A., Friedman, J., Gospodarowicz, D., and Fiddes, J. C. Human basic fibroblast growth factor: nucleotide sequence and genomic organization. EMBO J., 5: 2523-2528, 1986.
29. Johnson, D. E., Lee, P. L., Lu, J., and Williams, L. T. Diverse forms of a receptor for acidic and basic fibroblast growth factors. Mol. Cell, Biol., 10: 4728-4739, 1990.
30. Walgenbach, K. J., Gratas, C., Shestak, K. C., and Becker, D. Ischemia-induced expression of bFGF in normal skeletal muscle: a potential mechanism for mediating angiogenesis in ischaemic skeletal muscle. Nat. Med., 1: 453-459, 1995.
31. Rodeck, U., Herlyn, M., Herlyn, D., Molthoff, C., Atkinson, B., Varello, M., Steplewski, Z., and Koprowski, H. Tumor growth modulation by a monoclonal antibody to the epidermal growth factor receptor: immunologically mediated and effector cell-independent effects. Cancer Res., 47: 3692-3696, 1987.
32. Sers, C., Riethmuller, G., and Johnson, J. P. MUC18, a melanoma-progression associated molecule, and its potential role in tumor vascularization and hematogenous spread. Cancer Res., 54: 5689-5694, 1994.
33. Felding-Habermann, B., Mueller, B. M., Romerdahl, C. A., and Cheresh, D. A. Involvement of integrin αν gene expression in human melanoma tumorigenicity. J. Clin. Invest., 89: 2018-2022, 1992.