Synthesis and evaluation of bivalent NDP-α-MSH(7) peptide ligands for binding to the human melanocortin receptor 4 (hMC4R)

Bioconjugate Chemistry

Volumn 18, Issue 4, 2007, Pages 1101-1109

  Handl, Heather L ^b   Sankaranarayanan, Rajesh ^a   Josan, Jatinder S ^a   Vagner, Josef ^a   Mash, Eugene A ^a   Gillies, Robert J ^b   Hruby, Victor J ^a  

^a University of Arizona   (United States)

^b UNIVERSITY OF ARIZONA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; BINDING SITES; CHELATION; MEDICAL IMAGING; POLYETHYLENE GLYCOLS;

BIVALENT LIGANDS; CANCER IMAGING; CANCER THERAPY; HEPTAPEPTIDES; HIGH AFFINITY; MELANOCORTINS; MULTIVALENT LIGANDS; PEPTIDE LIGAND; POTENTIAL UTILITY; PRO-GLY;

LIGANDS;

ALPHA INTERMEDIN; ALPHA INTERMEDIN[4 NORLEUCINE 7 DEXTRO PHENYLALANINE]; G PROTEIN COUPLED RECEPTOR; GLYCINE; HEPTAPEPTIDE; LIGAND; MACROGOL; MELANOCORTIN 4 RECEPTOR; PROLINE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CROSS LINKING; DRUG BINDING SITE; DRUG CONFORMATION; DRUG RECEPTOR BINDING; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LIGAND BINDING; MOLECULAR MODEL; MONTE CARLO METHOD;

EID: 34547181796     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc0603642     Document Type: Article

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