End-capping of the modified melanocortin tetrapeptide (p-Cl)Phe-D-Phe-Arg- Trp-NH 2 as a route to hMC4R agonists

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 19, 2004, Pages 4839-4842

  Koikov, L N ^a   Ebetino, F H ^b   Hayes, J C ^b   Cross Doersen, D ^b   Knittel, J J ^a  

^a UNIVERSITY OF CINCINNATI   (United States)

^b PROCTER AND GAMBLE COMPANY   (United States)

Author keywords

Melanocortin receptor agonists

Indexed keywords

AMIDE; AMINO ACID DERIVATIVE; ANTIOBESITY AGENT; HORMONE RECEPTOR STIMULATING AGENT; LK 71; LK 75; MELANOCORTIN; MELANOCORTIN 1 RECEPTOR; MELANOCORTIN 3 RECEPTOR; MELANOCORTIN 4 RECEPTOR; MELANOCORTIN 4 RECEPTOR AGONIST; PHENYLALANINE DEXTRO PHENYLALANYLARGINYLTRYPTOPHANAMIDE; TETRAPEPTIDE; UNCLASSIFIED DRUG; UREA DERIVATIVE;

ARTICLE; CHEMICAL MODIFICATION; DRUG SELECTIVITY; DRUG SYNTHESIS; STRUCTURE ACTIVITY RELATION;

ALPHA-MSH; HUMANS; OLIGOPEPTIDES; RECEPTOR, MELANOCORTIN, TYPE 4; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 4444326526     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.07.046     Document Type: Article

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