Maspin expression is regulated by the non-canonical NF-κB subunit in androgen-insensitive prostate cancer cell lines

Molecular Immunology

Volumn 49, Issue 1-2, 2011, Pages 8-17

  Guo, Feng ^a   Kang, Suya ^a   Zhou, Peng ^a   Guo, Linchuan ^a   Ma, Liang ^a   Hou, Jianquan ^a  

^a THE FIRST AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

Author keywords

Maspin; Prostate cancer; RelA; RelB

Indexed keywords

ANDROGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MASPIN; TRANSCRIPTION FACTOR RELB;

ARTICLE; CANCER CELL; CANCER RESISTANCE; CELL DEATH; CONTROLLED STUDY; CORRELATION ANALYSIS; HOMEOSTASIS; HUMAN; HUMAN CELL; MALE; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

BLOTTING, WESTERN; CELL LINE, TUMOR; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GENE EXPRESSION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; PROSTATIC NEOPLASMS; REAL-TIME POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; SERPINS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR RELA; TRANSCRIPTION FACTOR RELB;

EID: 82455212908     PISSN: 01615890     EISSN: 18729142     Source Type: Journal    
DOI: 10.1016/j.molimm.2011.07.013     Document Type: Article

References (30)

1. Ben Shachar B., Feldstein O., Hacohen D., Ginsberg D. The tumor suppressor maspin mediates E2F1-induced sensitivity of cancer cells to chemotherapy. Mol. Cancer Res. 2010, 8:363-372.
2. Eitel J.A., Bijangi-Vishehsaraei K., Saadatzadeh M.R., Bhavsar J.R., Murphy M.P., Pollok K.E., Mayo L.D. PTEN and p53 are required for hypoxia induced expression of maspin in glioblastoma cells. Cell Cycle 2009, 8:896-901.
3. Guo F., Sun A., Wang W., He J., Hou J., Zhou P., Chen Z. TRAF1 is involved in the classical NF-kappaB activation and CD30-induced alternative activity in Hodgkin's lymphoma cells. Mol. Immunol. 2009, 46:2441-2448.
4. Guo F., Tanzer S., Busslinger M., Weih F. Lack of nuclear factor-kappa B2/p100 causes a RelB-dependent block in early B lymphopoiesis. Blood 2008, 112:551-559.
5. Guo F., Weih D., Meier E., Weih F. Constitutive alternative NF-kappaB signaling promotes marginal zone B-cell development but disrupts the marginal sinus and induces HEV-like structures in the spleen. Blood 2007, 110:2381-2389.
6. Holley A.K., Xu Y., St Clair D.K., St Clair W.H. RelB regulates manganese superoxide dismutase gene and resistance to ionizing radiation of prostate cancer cells. Ann. N. Y. Acad. Sci. 2010, 1201:129-136.
7. Katakura H., Takenaka K., Nakagawa M., Sonobe M., Adachi M., Ito S., Wada H., Tanaka F. Maspin gene expression is a significant prognostic factor in resected non-small cell lung cancer (NSCLC). Maspin in NSCLC. Lung Cancer 2006, 51:323-328.
8. Lam L.T., Davis R.E., Ngo V.N., Lenz G., Wright G., Xu W., Zhao H., Yu X., Dang L., Staudt L.M. Compensatory IKKalpha activation of classical NF-kappaB signaling during IKKbeta inhibition identified by an RNA interference sensitization screen. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:20798-20803.
9. Li X., Chen D., Yin S., Meng Y., Yang H., Landis-Piwowar K.R., Li Y., Sarkar F.H., Reddy G.P., Dou Q.P., Sheng S. Maspin augments proteasome inhibitor-induced apoptosis in prostate cancer cells. J. Cell. Physiol. 2007, 212:298-306.
10. Liu J., Yin S., Reddy N., Spencer C., Sheng S. Bax mediates the apoptosis-sensitizing effect of maspin. Cancer Res. 2004, 64:1703-1711.
11. Lonardo F., Li X., Kaplun A., Soubani A., Sethi S., Gadgeel S., Sheng S. The natural tumor suppressor protein maspin and potential application in non small cell lung cancer. Curr. Pharm. Des. 2010, 16:1877-1881.
12. Luo J.L., Tan W., Ricono J.M., Korchynskyi O., Zhang M., Gonias S.L., Cheresh D.A., Karin M. Nuclear cytokine-activated IKKalpha controls prostate cancer metastasis by repressing Maspin. Nature 2007, 446:690-694.
13. Mineva N.D., Wang X., Yang S., Ying H., Xiao Z.X., Holick M.F., Sonenshein G.E. Inhibition of RelB by 1,25-dihydroxyvitamin D3 promotes sensitivity of breast cancer cells to radiation. J. Cell. Physiol. 2009, 220:593-599.
14. Mohsin S.K., Zhang M., Clark G.M., Craig Allred D. Maspin expression in invasive breast cancer: association with other prognostic factors. J. Pathol. 2003, 199:432-435.
15. Nam E., Park C. Maspin suppresses survival of lung cancer cells through modulation of Akt pathway. Cancer Res. Treat. 2010, 42:42-47.
16. Narayan M., Twining S. Focus on molecules: maspin. Exp. Eye Res. 2010, 90:2-3.
17. O'Connor S., Shumway S.D., Amanna I.J., Hayes C.E., Miyamoto S. Regulation of constitutive p50/c-Rel activity via proteasome inhibitor-resistant IkappaBalpha degradation in B cells. Mol. Cell. Biol. 2004, 24:4895-4908.
18. Shen M.M., Abate-Shen C. Molecular genetics of prostate cancer: new prospects for old challenges. Genes Dev. 2010, 24:1967-2000.
19. Suh J., Rabson A.B. NF-kappaB activation in human prostate cancer: important mediator or epiphenomenon?. J. Cell. Biochem. 2004, 91:100-117.
20. Surowiak P., Materna V., Drag-Zalesinska M., Wojnar A., Kaplenko I., Spaczynski M., Dietel M., Zabel M., Lage H. Maspin expression is characteristic for cisplatin-sensitive ovarian cancer cells and for ovarian cancer cases of longer survival rates. Int. J. Gynecol. Pathol. 2006, 25:131-139.
21. Vallabhapurapu S., Karin M. Regulation and function of NF-kappaB transcription factors in the immune system. Annu. Rev. Immunol. 2009, 27:693-733.
22. Weih F., Caamano J. Regulation of secondary lymphoid organ development by the nuclear factor-kappaB signal transduction pathway. Immunol. Rev. 2003, 195:91-105.
23. Xu Y., Fang F., St Clair D.K., Josson S., Sompol P., Spasojevic I., St Clair W.H. Suppression of RelB-mediated manganese superoxide dismutase expression reveals a primary mechanism for radiosensitization effect of 1alpha,25-dihydroxyvitamin D(3) in prostate cancer cells. Mol. Cancer Ther. 2007, 6:2048-2056.
24. Xu Y., Fang F., Sun Y., St Clair D.K., St Clair W.H. RelB-dependent differential radiosensitization effect of STI571 on prostate cancer cells. Mol. Cancer Ther. 2010, 9:803-812.
25. Xu Y., Josson S., Fang F., Oberley T.D., St Clair D.K., Wan X.S., Sun Y., Bakthavatchalu V., Muthuswamy A., St Clair W.H. RelB enhances prostate cancer growth: implications for the role of the nuclear factor-kappaB alternative pathway in tumorigenicity. Cancer Res. 2009, 69:3267-3271.
26. Yemelyanov A., Czwornog J., Chebotaev D., Karseladze A., Kulevitch E., Yang X., Budunova I. Tumor suppressor activity of glucocorticoid receptor in the prostate. Oncogene 2007, 26:1885-1896.
27. Zhang M., Magit D., Sager R. Expression of maspin in prostate cells is regulated by a positive ets element and a negative hormonal responsive element site recognized by androgen receptor. Proc. Natl. Acad. Sci. U. S. A. 1997, 94:5673-5678.
28. Zou Z., Anisowicz A., Hendrix M.J., Thor A., Neveu M., Sheng S., Rafidi K., Seftor E., Sager R. Maspin, a serpin with tumor-suppressing activity in human mammary epithelial cells. Science 1994, 263:526-529.
29. Zou Z., Gao C., Nagaich A.K., Connell T., Saito S., Moul J.W., Seth P., Appella E., Srivastava S. p53 regulates the expression of the tumor suppressor gene maspin. J. Biol. Chem. 2000, 275:6051-6054.
30. Zou Z., Zhang W., Young D., Gleave M.G., Rennie P., Connell T., Connelly R., Moul J., Srivastava S., Sesterhenn I. Maspin expression profile in human prostate cancer (CaP) and in vitro induction of Maspin expression by androgen ablation. Clin. Cancer Res. 2002, 8:1172-1177.