Maspin expression profile in human prostate cancer (CaP) and in vitro induction of Maspin expression by androgen ablation

Clinical Cancer Research

Volumn 8, Issue 5, 2002, Pages 1172-1177

  Zou, Zhiqiang ^a   Zhang, Wei ^b   Young, Denise ^b   Gleave, Martin G ^c   Rennie, Paul ^c   Connell, Theresa ^a   Connelly, Roger ^a   Moul, Judd ^a,d   Srivastava, Shiv ^a   Sesterhenn, Isabell ^b  

^a UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

^b ARMED FORCES INSTITUTE OF PATHOLOGY   (United States)

^c VANCOUVER GENERAL HOSPITAL   (Canada)

^d WALTER REED ARMY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN; MASPIN;

ADULT; AGED; ARTICLE; BREAST CANCER; CANCER INVASION; CLINICAL ARTICLE; GENE EXPRESSION; HORMONE INHIBITION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; METASTASIS; PATHOLOGY; PRIORITY JOURNAL; PROSTATE; PROSTATE CANCER; PROSTATECTOMY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR SUPPRESSOR GENE;

AGED; ANDROGENS; GENE EXPRESSION REGULATION; GENES, TUMOR SUPPRESSOR; HUMANS; IMMUNOHISTOCHEMISTRY; LUCIFERASES; MALE; MIDDLE AGED; PROMOTER REGIONS (GENETICS); PROSTATIC NEOPLASMS; PROTEIN BIOSYNTHESIS; PROTEINS; RECOMBINANT FUSION PROTEINS; RNA, NEOPLASM; SERPINS; TIME FACTORS; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0036091360     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Maspin, a serpin with tumor-suppressing activity in human mammary epithelial cells
2. p53 regulates the expression of the tumor suppressor gene maspin
3. Maspin gene expression in tumor suppression induced by overexpressing manganese-containing superoxide dismutase cDNA in human breast cancer cells
4. γ-linolenic acid regulates expression of maspin and the motility of cancer cells
5. Transactivation through Ets and Apl transcription sites determines the expression of the tumor-suppressing gene maspin
6. Epigenetic silencing of maspin gene expression in human breast cancers
7. Maspin is an angiogenesis inhibitor
8. Androgen-regulated gene expression in prostate cancer
9. Mutations in the androgen receptor gene are associated with progression of human prostate cancer to androgen independence
10. In vivo amplification of the androgen receptor gene and progression of human prostate cancer
11. Androgen receptor gene amplification: A possible molecular mechanism for androgen deprivation therapy failure in prostate cancer
12. Mutant androgen receptor detected in an advanced-stage prostatic carcinoma is activated by adrenal androgens and progesterone
13. CWR22: The first human prostate cancer xenograft with strongly androgen-dependent and relapsed strains both in vivo and in soft agar
14. Histologic grading and clinical staging of prostatic carcinoma
15. International Histological Classification of Prostatic Tumor, Geneva
16. Ki-67 expression is a prognostic marker of prostate cancer recurrence after radical prostatectomy
17. High tumoral maspin expression is associated with improved survival of patients with oral squamous cell carcinoma
18. Expression of the tumor suppressor gene maspin in human pancreatic cancers
19. Expression of maspin in prostate cells is regulated by a positive ets element and a negative hormonal responsive element site recognized by androgen receptor