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Volumn 70, Issue 20, 2008, Pages 1916-1925

Invited Article: Nervous system pathology in sporadic Parkinson disease

Author keywords

[No Author keywords available]

Indexed keywords

HISTOPATHOLOGY; HUMAN; MOTOR DYSFUNCTION; NEUROLOGIC DISEASE; NEUROPATHOLOGY; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN FOLDING; REVIEW;

EID: 43649106356     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/01.wnl.0000312279.49272.9f     Document Type: Article
Times cited : (468)

References (76)
  • 1
    • 33745919520 scopus 로고    scopus 로고
    • Epidemiology of Parkinson’s disease
    • LML de Lau MMB Breteler Epidemiology of Parkinson’s disease Lancet Neurol 5 2006 525 535
    • (2006) Lancet Neurol , vol.5 , pp. 525-535
    • de Lau, LML1    Breteler, MMB2
  • 2
    • 0026348872 scopus 로고
    • Pathology of Parkinson’s disease. Changes other than the nigrostriatal pathway
    • KA Jellinger Pathology of Parkinson’s disease. Changes other than the nigrostriatal pathway Molec Chem Neuropathol 14 1991 153 197
    • (1991) Molec Chem Neuropathol , vol.14 , pp. 153-197
    • Jellinger, KA1
  • 3
    • 0032531924 scopus 로고    scopus 로고
    • Parkinson’s disease
    • AE Lang AM Lozano Parkinson’s disease N Engl J Med 339 1998 1044 1053 1130-1143
    • (1998) N Engl J Med , vol.339 , pp. 1044-1053
    • Lang, AE1    Lozano, AM2
  • 4
    • 0035706436 scopus 로고    scopus 로고
    • The cellular pathology of Parkinson’s disease
    • H Takahashi K Wakabayashi The cellular pathology of Parkinson’s disease Neuropathology 21 2001 315 322
    • (2001) Neuropathology , vol.21 , pp. 315-322
    • Takahashi, H1    Wakabayashi, K2
  • 5
    • 1942520420 scopus 로고    scopus 로고
    • Challenges in Parkinson’s disease: restoration of the nigrostriatal dopamine system is not enough
    • AE Lang JA Obeso Challenges in Parkinson’s disease: restoration of the nigrostriatal dopamine system is not enough Lancet Neurol 3 2004 309 316
    • (2004) Lancet Neurol , vol.3 , pp. 309-316
    • Lang, AE1    Obeso, JA2
  • 6
    • 18144412688 scopus 로고    scopus 로고
    • Challenging conventional wisdom: the etiologic role of dopamine oxidative stress in Parkinson’s disease
    • JE Ahlskog Challenging conventional wisdom: the etiologic role of dopamine oxidative stress in Parkinson’s disease Mov Disord 20 2005 271 282
    • (2005) Mov Disord , vol.20 , pp. 271-282
    • Ahlskog, JE1
  • 7
    • 33645755812 scopus 로고    scopus 로고
    • The Parkinson’s complex: parkinsonism is just the tip of the iceberg
    • JW Langston The Parkinson’s complex: parkinsonism is just the tip of the iceberg Ann Neurol 59 2006 591 596
    • (2006) Ann Neurol , vol.59 , pp. 591-596
    • Langston, JW1
  • 8
    • 34147101621 scopus 로고    scopus 로고
    • The etiopathogenesis of Parkinson’s disease and suggestions for further research
    • I Litvan G Halliday M Hallett The etiopathogenesis of Parkinson’s disease and suggestions for further research J Neuropathol Exp Neurol 66 2007 251 257
    • (2007) J Neuropathol Exp Neurol , vol.66 , pp. 251-257
    • Litvan, I1    Halliday, G2    Hallett, M3
  • 9
    • 0038727936 scopus 로고    scopus 로고
    • Description of Parkinson’s disease as a clinical syndrome
    • S Fahn Description of Parkinson’s disease as a clinical syndrome Ann NY Acad Sci 991 2003 1 14
    • (2003) Ann NY Acad Sci , vol.991 , pp. 1-14
    • Fahn, S1
  • 10
    • 0033776941 scopus 로고    scopus 로고
    • Diffuse Lewy body disease
    • K Kosaka Diffuse Lewy body disease Neuropathol 20 2000 73 78
    • (2000) Neuropathol , vol.20 , pp. 73-78
    • Kosaka, K1
  • 11
    • 34047223232 scopus 로고    scopus 로고
    • DLB and PDD boundary issues: Diagnosis, treatment, molecular pathology, and biomarkers
    • CE Lippa JE Duda M Grossman DLB and PDD boundary issues: Diagnosis, treatment, molecular pathology, and biomarkers Neurology 68 2007 812 819
    • (2007) Neurology , vol.68 , pp. 812-819
    • Lippa, CE1    Duda, JE2    Grossman, M3
  • 12
    • 33144489150 scopus 로고    scopus 로고
    • Diagnosis and management of dementia with Lewy bodies. Third report of the DLB consortium
    • IG McKeith DW Dickson J Lowe Diagnosis and management of dementia with Lewy bodies. Third report of the DLB consortium Neurology 65 2005 1863 1872
    • (2005) Neurology , vol.65 , pp. 1863-1872
    • McKeith, IG1    Dickson, DW2    Lowe, J3
  • 13
    • 0034827449 scopus 로고    scopus 로고
    • Cortical Lewy body pathology in the diagnosis of dementia
    • AJ Harding GM Halliday Cortical Lewy body pathology in the diagnosis of dementia Acta Neuropathol 102 2001 355 363
    • (2001) Acta Neuropathol , vol.102 , pp. 355-363
    • Harding, AJ1    Halliday, GM2
  • 14
    • 0036869833 scopus 로고    scopus 로고
    • Parkinson’s disease and dementia with Lewy bodies: one disease or two?
    • IH Richard M Papka A Rubio R Kurlan Parkinson’s disease and dementia with Lewy bodies: one disease or two? Mov Disord 17 2002 1161 1165
    • (2002) Mov Disord , vol.17 , pp. 1161-1165
    • Richard, IH1    Papka, M2    Rubio, A3    Kurlan, R4
  • 15
    • 0037928426 scopus 로고    scopus 로고
    • Lewy body cortical involvement may not always predict dementia in Parkinson’s disease
    • C Colosimo AJ Hughes L Kilford AJ Lees Lewy body cortical involvement may not always predict dementia in Parkinson’s disease J Neurol Neurosurg Psychiatry 74 2003 852 856
    • (2003) J Neurol Neurosurg Psychiatry , vol.74 , pp. 852-856
    • Colosimo, C1    Hughes, AJ2    Kilford, L3    Lees, AJ4
  • 16
    • 4344643801 scopus 로고    scopus 로고
    • Are Parkinson’s disease with dementia and dementia with Lewy bodies the same entity?
    • D Aarsland CG Ballard G Halliday Are Parkinson’s disease with dementia and dementia with Lewy bodies the same entity? J Geriatr Psychiatry Neurol 17 2004 137 145
    • (2004) J Geriatr Psychiatry Neurol , vol.17 , pp. 137-145
    • Aarsland, D1    Ballard, CG2    Halliday, G3
  • 17
    • 33750969676 scopus 로고    scopus 로고
    • Clinical phenotype of Parkinson disease dementia
    • JE Galvin J Pollack JC Morris Clinical phenotype of Parkinson disease dementia Neurology 67 2006 1605 1611
    • (2006) Neurology , vol.67 , pp. 1605-1611
    • Galvin, JE1    Pollack, J2    Morris, JC3
  • 18
    • 34648819365 scopus 로고    scopus 로고
    • The Lewy body in Parkinson’s disease: molecules implicated in the formation and degradation of alpha-synuclein aggregates
    • K Wakabayashi K Tanji F Mori H Takahashi The Lewy body in Parkinson’s disease: molecules implicated in the formation and degradation of alpha-synuclein aggregates Neuropathology 27 2007 494 506
    • (2007) Neuropathology , vol.27 , pp. 494-506
    • Wakabayashi, K1    Tanji, K2    Mori, F3    Takahashi, H4
  • 19
    • 0034661820 scopus 로고    scopus 로고
    • Neuropathology of synuclein aggregates: new insights into mechanism of neurodegenerative diseases
    • JE Duda VMY Lee JQ Trojanowski Neuropathology of synuclein aggregates: new insights into mechanism of neurodegenerative diseases J Neurosci Res 61 2000 121 127
    • (2000) J Neurosci Res , vol.61 , pp. 121-127
    • Duda, JE1    Lee, VMY2    Trojanowski, JQ3
  • 20
    • 84940364788 scopus 로고    scopus 로고
    • α-Synuclein and the Lewy body disorders
    • DW Dickson α-Synuclein and the Lewy body disorders Curr Opinion Neurol 14 2001 423 432
    • (2001) Curr Opinion Neurol , vol.14 , pp. 423-432
    • Dickson, DW1
  • 21
    • 0035370261 scopus 로고    scopus 로고
    • The significance of tau and α-synuclein inclusions in neurodegenerative diseases
    • M Goedert The significance of tau and α-synuclein inclusions in neurodegenerative diseases Curr Opin Genet Develop 11 2001 343 351
    • (2001) Curr Opin Genet Develop , vol.11 , pp. 343-351
    • Goedert, M1
  • 22
    • 0344305371 scopus 로고    scopus 로고
    • Morphogenesis of Lewy bodies: dissimilar incorporation of α-synuclein, ubiquitin, and p62
    • E Kuusisto L Parkkinen I Alafuzoff Morphogenesis of Lewy bodies: dissimilar incorporation of α-synuclein, ubiquitin, and p62 J Neuropathol Exp Neurol 62 2003 1241 1253
    • (2003) J Neuropathol Exp Neurol , vol.62 , pp. 1241-1253
    • Kuusisto, E1    Parkkinen, L2    Alafuzoff, I3
  • 23
    • 20344371211 scopus 로고    scopus 로고
    • Alpha-synuclein lesions in normal aging, Parkinson disease, and Alzheimer disease: evidence from the Baltimore Longitudinal Study of Aging (BLSA)
    • I Mikolaenko O Pletnikova CH Kawas Alpha-synuclein lesions in normal aging, Parkinson disease, and Alzheimer disease: evidence from the Baltimore Longitudinal Study of Aging (BLSA) J Neuropath Exp Neurol 64 2005 156 162
    • (2005) J Neuropath Exp Neurol , vol.64 , pp. 156-162
    • Mikolaenko, I1    Pletnikova, O2    Kawas, CH3
  • 24
    • 85119774667 scopus 로고    scopus 로고
    • Physiological and pathological properties of alpha-synuclein
    • GK Tofaris MG Spillantini Physiological and pathological properties of alpha-synuclein Cell Life Mol Sci 64 2007 2914 2201
    • (2007) Cell Life Mol Sci , vol.64 , pp. 2914
    • Tofaris, GK1    Spillantini, MG2
  • 25
    • 0035109738 scopus 로고    scopus 로고
    • Synucleinopathies. Clinical and pathological implications
    • JE Galvin VMY Lee JQ Trojanowski Synucleinopathies. Clinical and pathological implications Arch Neurol 58 2001 186 190
    • (2001) Arch Neurol , vol.58 , pp. 186-190
    • Galvin, JE1    Lee, VMY2    Trojanowski, JQ3
  • 27
    • 0014525843 scopus 로고
    • Concentric hyalin intraneuronal inclusions of Lewy type in the brain of elderly persons (50 incidental cases): relationship to parkinsonism
    • LS Forno Concentric hyalin intraneuronal inclusions of Lewy type in the brain of elderly persons (50 incidental cases): relationship to parkinsonism J Am Geriatr Soc 17 1969 557 575
    • (1969) J Am Geriatr Soc , vol.17 , pp. 557-575
    • Forno, LS1
  • 29
    • 33646082266 scopus 로고    scopus 로고
    • α-Synuclein pathology of the spinal and peripheral autonomic nervous system in neurologically unimpaired elderly subjects
    • A Bloch A Probst H Bissig H Adams M Tolnay α-Synuclein pathology of the spinal and peripheral autonomic nervous system in neurologically unimpaired elderly subjects Neuropathol Appl Neurobiol 12 2006 284 295
    • (2006) Neuropathol Appl Neurobiol , vol.12 , pp. 284-295
    • Bloch, A1    Probst, A2    Bissig, H3    Adams, H4    Tolnay, M5
  • 30
    • 33749022060 scopus 로고    scopus 로고
    • Association of olfactory dysfunction with incidental Lewy bodies
    • GW Ross RD Abbott H Petrovitch Association of olfactory dysfunction with incidental Lewy bodies Mov Disord 21 2006 2062 2067
    • (2006) Mov Disord , vol.21 , pp. 2062-2067
    • Ross, GW1    Abbott, RD2    Petrovitch, H3
  • 31
    • 34748826388 scopus 로고    scopus 로고
    • Bowel movement frequency in late-life and incidental Lewy bodies
    • RD Abbott GW Ross H Petrovitch Bowel movement frequency in late-life and incidental Lewy bodies Mov Disord 22 2007 1581 1586
    • (2007) Mov Disord , vol.22 , pp. 1581-1586
    • Abbott, RD1    Ross, GW2    Petrovitch, H3
  • 32
    • 7944238570 scopus 로고    scopus 로고
    • Lewy-body-related α-synucleinopathy in the aged human brain
    • KA Jellinger Lewy-body-related α-synucleinopathy in the aged human brain J Neural Transm 111 2004 1219 1235
    • (2004) J Neural Transm , vol.111 , pp. 1219-1235
    • Jellinger, KA1
  • 34
    • 0032926674 scopus 로고    scopus 로고
    • Lewy body-type degeneration in cardiac plexus in Parkinson’s and incidental Lewy body disease
    • K Iwanaga K Wakabayashi M Yoshimoto Lewy body-type degeneration in cardiac plexus in Parkinson’s and incidental Lewy body disease Neurology 52 1999 1269 1271
    • (1999) Neurology , vol.52 , pp. 1269-1271
    • Iwanaga, K1    Wakabayashi, K2    Yoshimoto, M3
  • 35
    • 0024512326 scopus 로고
    • The significance of the Lewy body in the diagnosis of idiopathic Parkinson’s disease
    • WRG Gibb AJ Lees The significance of the Lewy body in the diagnosis of idiopathic Parkinson’s disease Neuropathol Appl Neurobiol 15 1989 27 44
    • (1989) Neuropathol Appl Neurobiol , vol.15 , pp. 27-44
    • Gibb, WRG1    Lees, AJ2
  • 36
    • 33751118534 scopus 로고    scopus 로고
    • Age-associated increases of alpha-synuclein in monkeys and humans are associated with nigrostriatal dopamine depletion: Is this the target for Parkinson’s disease?
    • Y Chu JH Kordower Age-associated increases of alpha-synuclein in monkeys and humans are associated with nigrostriatal dopamine depletion: Is this the target for Parkinson’s disease? Neurobiol Dis 25 2007 134 149
    • (2007) Neurobiol Dis , vol.25 , pp. 134-149
    • Chu, Y1    Kordower, JH2
  • 37
    • 41149129792 scopus 로고    scopus 로고
    • Reduced striatal tyrosine hydroxylase in incidental Lewy body disease
    • TG Beach CH Adler LI Sue Reduced striatal tyrosine hydroxylase in incidental Lewy body disease Acta Neuropathol 115 2007 445 451
    • (2007) Acta Neuropathol , vol.115 , pp. 445-451
    • Beach, TG1    Adler, CH2    Sue, LI3
  • 38
    • 41149115508 scopus 로고    scopus 로고
    • Evidence that incidental Lewy body disease is presymptomatic Parkinson’s disease
    • DW Dickson H Fujishiro A DelleDonne Evidence that incidental Lewy body disease is presymptomatic Parkinson’s disease Acta Neuropathol 115 2008 437 444
    • (2008) Acta Neuropathol , vol.115 , pp. 437-444
    • Dickson, DW1    Fujishiro, H2    DelleDonne, A3
  • 39
    • 0026635322 scopus 로고
    • Preliminary diagnosis of Parkinson’s disease by olfactory bulb pathology
    • SE Daniel CH Hawkes Preliminary diagnosis of Parkinson’s disease by olfactory bulb pathology Lancet 340 1992 186
    • (1992) Lancet , vol.340 , pp. 186
    • Daniel, SE1    Hawkes, CH2
  • 40
    • 32544442518 scopus 로고    scopus 로고
    • Gastric α-synuclein immunoreactive inclusions in Meissner’s and Auerbach’s plexuses in cases staged for Parkinson’s disease-related brain pathology
    • H Braak RAI de Vos J Bohl K Del Tredici Gastric α-synuclein immunoreactive inclusions in Meissner’s and Auerbach’s plexuses in cases staged for Parkinson’s disease-related brain pathology Neurosci Lett 396 2006 67 72
    • (2006) Neurosci Lett , vol.396 , pp. 67-72
    • Braak, H1    de Vos, RAI2    Bohl, J3    Del Tredici, K4
  • 41
    • 33646109064 scopus 로고    scopus 로고
    • α-Synuclein pathology in the spinal cord of neurologically asymptomatic aged individuals
    • KJ Klos JE Ahlskog KA Josephs α-Synuclein pathology in the spinal cord of neurologically asymptomatic aged individuals Neurology 66 2006 1100 1102
    • (2006) Neurology , vol.66 , pp. 1100-1102
    • Klos, KJ1    Ahlskog, JE2    Josephs, KA3
  • 42
    • 33947200337 scopus 로고    scopus 로고
    • Parkinson’s disease: lesions in dorsal horn layer I, involvement of parasympathetic and sympathetic pre- and postganglionic neurons
    • H Braak M Sastre JRE Bohl RAI de Vos K Del Tredici Parkinson’s disease: lesions in dorsal horn layer I, involvement of parasympathetic and sympathetic pre- and postganglionic neurons Acta Neuropathol 113 2007 421 429
    • (2007) Acta Neuropathol , vol.113 , pp. 421-429
    • Braak, H1    Sastre, M2    Bohl, JRE3    de Vos, RAI4    Del Tredici, K5
  • 43
    • 34249907298 scopus 로고    scopus 로고
    • Do α-synuclein aggregates in autonomic plexuses predate Lewy body disorders? A cohort study
    • A Minguez-Castellanos CE Chamorro F Escamilla-Sevilla Do α-synuclein aggregates in autonomic plexuses predate Lewy body disorders? A cohort study Neurology 68 2007 2012 2018
    • (2007) Neurology , vol.68 , pp. 2012-2018
    • Minguez-Castellanos, A1    Chamorro, CE2    Escamilla-Sevilla, F3
  • 44
    • 0026447670 scopus 로고
    • Age-related loss of dorsal vagal neurons in Parkinson’s disease
    • WP Gai PC Blumbergs LB Geffen WW Blessing Age-related loss of dorsal vagal neurons in Parkinson’s disease Neurology 42 1992 2106 2111
    • (1992) Neurology , vol.42 , pp. 2106-2111
    • Gai, WP1    Blumbergs, PC2    Geffen, LB3    Blessing, WW4
  • 45
    • 0038748401 scopus 로고    scopus 로고
    • Idiopathic Parkinson’s disease: possible routes by which vulnerable neuronal types may be subject to neuroinvasion by an unknown pathogen
    • H Braak U Rüb WP Gai K Del Tredici Idiopathic Parkinson’s disease: possible routes by which vulnerable neuronal types may be subject to neuroinvasion by an unknown pathogen J Neural Transm 110 2003 517 536
    • (2003) J Neural Transm , vol.110 , pp. 517-536
    • Braak, H1    Rüb, U2    Gai, WP3    Del Tredici, K4
  • 46
    • 85119732635 scopus 로고    scopus 로고
    • Phillips RJ, Walter GC, Wilder SL, Baronowski EA, Powley TL. Alpha-synuclein immunopositive myenteric neurons and vagal preganglionic terminals: autonomic pathway implicated in Parkinson’s disease? Neuroscience Epub 2008 Mar 18.
  • 47
    • 41149111808 scopus 로고    scopus 로고
    • A not entirely benign procedure: progression of Parkinson’s disease
    • K Del Tredici H Braak A not entirely benign procedure: progression of Parkinson’s disease Acta Neuropathol 115 2008 379 384
    • (2008) Acta Neuropathol , vol.115 , pp. 379-384
    • Del Tredici, K1    Braak, H2
  • 48
    • 0027343653 scopus 로고
    • Lewy bodies in the visceral autonomic nervous system in Parkinson’s disease
    • K Wakabayashi H Takahashi E Ohama S Takeda F Ikuta Lewy bodies in the visceral autonomic nervous system in Parkinson’s disease Adv Neurol 60 1993 609 612
    • (1993) Adv Neurol , vol.60 , pp. 609-612
    • Wakabayashi, K1    Takahashi, H2    Ohama, E3    Takeda, S4    Ikuta, F5
  • 49
    • 0030662269 scopus 로고    scopus 로고
    • Neuropathology of autonomic nervous system in Parkinson’s disease
    • K Wakabayashi H Takahashi Neuropathology of autonomic nervous system in Parkinson’s disease Eur Neurology 38 suppl 2 1997 2 7
    • (1997) Eur Neurology , vol.38 , Issue.suppl 2 , pp. 2-7
    • Wakabayashi, K1    Takahashi, H2
  • 50
    • 0344686368 scopus 로고    scopus 로고
    • The gastrointestinal tract as the portal of entry for foreign macromolecules: fate of DANN and proteins
    • M Palka-Santini B Schwarz-Henke M Hösel The gastrointestinal tract as the portal of entry for foreign macromolecules: fate of DANN and proteins Mol Genet Genom 270 2003 201 215
    • (2003) Mol Genet Genom , vol.270 , pp. 201-215
    • Palka-Santini, M1    Schwarz-Henke, B2    Hösel, M3
  • 51
    • 0034175614 scopus 로고    scopus 로고
    • Progressive postnatal assembly of limbic-autonomic circuits revealed by central transneuronal transport of pseudorabies virus
    • L Rinaman P Levitt JP Card Progressive postnatal assembly of limbic-autonomic circuits revealed by central transneuronal transport of pseudorabies virus J Neurosci 20 2000 2731 2741
    • (2000) J Neurosci , vol.20 , pp. 2731-2741
    • Rinaman, L1    Levitt, P2    Card, JP3
  • 52
    • 22144465494 scopus 로고    scopus 로고
    • Cardiac sympathetic denervation precedes neuronal loss in the sympathetic ganglia in Lewy body disease
    • S Orimo T Amino Y Itoh Cardiac sympathetic denervation precedes neuronal loss in the sympathetic ganglia in Lewy body disease Acta Neuropathol 109 2005 583 588
    • (2005) Acta Neuropathol , vol.109 , pp. 583-588
    • Orimo, S1    Amino, T2    Itoh, Y3
  • 53
    • 33847205751 scopus 로고    scopus 로고
    • Degeneration of cardiac sympathetic nerve begins in the early disease process of Parkinson’s disease
    • S Orimo A Takahashi T Uchihara Degeneration of cardiac sympathetic nerve begins in the early disease process of Parkinson’s disease Brain Pathol 17 2007 24 30
    • (2007) Brain Pathol , vol.17 , pp. 24-30
    • Orimo, S1    Takahashi, A2    Uchihara, T3
  • 54
    • 0035859865 scopus 로고    scopus 로고
    • Frequency of bowel movements and the future risk of Parkinson’s disease
    • RD Abbott H Petrovitch LR White Frequency of bowel movements and the future risk of Parkinson’s disease Neurology 57 2001 456 462
    • (2001) Neurology , vol.57 , pp. 456-462
    • Abbott, RD1    Petrovitch, H2    White, LR3
  • 56
    • 0041510529 scopus 로고    scopus 로고
    • Gastrointestinal dysfunction in Parkinson’s disease
    • RF Pfeiffer Gastrointestinal dysfunction in Parkinson’s disease Lancet Neurol 2 2003 107 116
    • (2003) Lancet Neurol , vol.2 , pp. 107-116
    • Pfeiffer, RF1
  • 57
    • 4644323707 scopus 로고    scopus 로고
    • Autonomic failure as the initial manifestation of Parkinson’s disease and dementia with Lewy bodies
    • H Kaufmann K Nahm D Purohit D Wolfe Autonomic failure as the initial manifestation of Parkinson’s disease and dementia with Lewy bodies Neurology 63 2004 1093 1095
    • (2004) Neurology , vol.63 , pp. 1093-1095
    • Kaufmann, H1    Nahm, K2    Purohit, D3    Wolfe, D4
  • 58
    • 0035736606 scopus 로고    scopus 로고
    • Pain: autonomic interactions: a selective review
    • EE Benarroch Pain: autonomic interactions: a selective review Clin Auton Res 11 2001 343 349
    • (2001) Clin Auton Res , vol.11 , pp. 343-349
    • Benarroch, EE1
  • 59
    • 3142743144 scopus 로고    scopus 로고
    • Pain in Parkinson’s disease
    • JI Sage Pain in Parkinson’s disease Curr Treat Options Neurol 6 2004 191 200
    • (2004) Curr Treat Options Neurol , vol.6 , pp. 191-200
    • Sage, JI1
  • 60
    • 24144458929 scopus 로고    scopus 로고
    • Pain in Parkinson’s disease and multiple sclerosis: Its relation to the medial and lateral pain systems
    • E Scherder E Wolters C Polman J Serfeant D Swaab Pain in Parkinson’s disease and multiple sclerosis: Its relation to the medial and lateral pain systems Neurosci Biobehav Rev 29 2005 1047 1056
    • (2005) Neurosci Biobehav Rev , vol.29 , pp. 1047-1056
    • Scherder, E1    Wolters, E2    Polman, C3    Serfeant, J4    Swaab, D5
  • 61
    • 34948821535 scopus 로고    scopus 로고
    • Pathophysiology of REM sleep behaviour disorder and relevance to neurodegenerative disease
    • BF Boeve MH Silber CB Saper Pathophysiology of REM sleep behaviour disorder and relevance to neurodegenerative disease Brain 69 2007 2770 2788
    • (2007) Brain , vol.69 , pp. 2770-2788
    • Boeve, BF1    Silber, MH2    Saper, CB3
  • 62
    • 0036171907 scopus 로고    scopus 로고
    • Parkinson’s disease: The thalamic components of the limbic loop are severely impaired by α-synuclein immunopositive inclusion body pathology
    • U Rüb K Del Tredici C Schultz Parkinson’s disease: The thalamic components of the limbic loop are severely impaired by α-synuclein immunopositive inclusion body pathology Neurobiol Aging 23 2002 245 254
    • (2002) Neurobiol Aging , vol.23 , pp. 245-254
    • Rüb, U1    Del Tredici, K2    Schultz, C3
  • 63
    • 0034705015 scopus 로고    scopus 로고
    • Alpha-synuclein cortical Lewy bodies correlate with dementia in Parkinson’s disease
    • HI Hurtig JQ Trojanowski J Galvin Alpha-synuclein cortical Lewy bodies correlate with dementia in Parkinson’s disease Neurology 54 2000 1916 1921
    • (2000) Neurology , vol.54 , pp. 1916-1921
    • Hurtig, HI1    Trojanowski, JQ2    Galvin, J3
  • 65
    • 34547727312 scopus 로고    scopus 로고
    • Development of α-synuclein immunoreactive astrocytes in the forebrain parallels stages of intraneuronal pathology in sporadic Parkinson’s disease
    • H Braak M Sastre K Del Tredici Development of α-synuclein immunoreactive astrocytes in the forebrain parallels stages of intraneuronal pathology in sporadic Parkinson’s disease Acta Neuropathol 114 2007 231 241
    • (2007) Acta Neuropathol , vol.114 , pp. 231-241
    • Braak, H1    Sastre, M2    Del Tredici, K3
  • 66
    • 85119747911 scopus 로고    scopus 로고
    • Duda JE, Noorigian JV, Petrovitch H, White LR, Ross GW. Pattern of Lewy pathology progression suggested by Braak staging system is supported by analysis of a population-based cohort of patients. The Mov Disord Society’s 11th International Congress Late Breaking Abstracts 2007;A3.
  • 67
    • 37549030958 scopus 로고    scopus 로고
    • Human-based studies on alpha-synuclein deposition and relationship to Parkinson’s disease symptoms
    • GM Halliday H McCann Human-based studies on alpha-synuclein deposition and relationship to Parkinson’s disease symptoms Exp Neurol 209 2008 12 21
    • (2008) Exp Neurol , vol.209 , pp. 12-21
    • Halliday, GM1    McCann, H2
  • 68
    • 11144241275 scopus 로고    scopus 로고
    • Alpha-synuclein pathology does not predict extrapyramidal symptoms or dementia
    • L Parkkinen T Kauppinen T Pirttila JM Autere I Alafuzoff Alpha-synuclein pathology does not predict extrapyramidal symptoms or dementia Ann Neurol 57 2005 82 91
    • (2005) Ann Neurol , vol.57 , pp. 82-91
    • Parkkinen, L1    Kauppinen, T2    Pirttila, T3    Autere, JM4    Alafuzoff, I5
  • 69
    • 41149141259 scopus 로고    scopus 로고
    • Applicability of current staging systems of α-synuclein pathology and their clinical relevance
    • L Parkkinen T Pirttilä I Alafuzoff Applicability of current staging systems of α-synuclein pathology and their clinical relevance Acta Neuropathol 115 2008 399 407
    • (2008) Acta Neuropathol , vol.115 , pp. 399-407
    • Parkkinen, L1    Pirttilä, T2    Alafuzoff, I3
  • 70
    • 0042974099 scopus 로고    scopus 로고
    • α-Synuclein pathology in Parkinson’s and Alzheimer’s disease brain: incidence and topographic distribution: a pilot study
    • KA Jellinger α-Synuclein pathology in Parkinson’s and Alzheimer’s disease brain: incidence and topographic distribution: a pilot study Acta Neuropathol 106 2003 191 201
    • (2003) Acta Neuropathol , vol.106 , pp. 191-201
    • Jellinger, KA1
  • 71
    • 0037383760 scopus 로고    scopus 로고
    • Regional distribution of alpha-synuclein pathology in unimpaired aging and Alzheimer’s disease
    • L Parkkinen H Soininen I Alafuzoff Regional distribution of alpha-synuclein pathology in unimpaired aging and Alzheimer’s disease J Neuropathol Exp Neurol 62 2003 363 367
    • (2003) J Neuropathol Exp Neurol , vol.62 , pp. 363-367
    • Parkkinen, L1    Soininen, H2    Alafuzoff, I3
  • 72
    • 33747821466 scopus 로고    scopus 로고
    • Alzheimer disease with amygdala Lewy bodies: a distinct form of alpha-synucleinopathy
    • H Uchikado WL Lin MW DeLucia DW Dickson Alzheimer disease with amygdala Lewy bodies: a distinct form of alpha-synucleinopathy J Neuropathol Exp Neurol 65 2006 685 697
    • (2006) J Neuropathol Exp Neurol , vol.65 , pp. 685-697
    • Uchikado, H1    Lin, WL2    DeLucia, MW3    Dickson, DW4
  • 73
    • 41149177434 scopus 로고    scopus 로고
    • The progression of pathology in longitudinally-followed patients with Parkinson’s disease
    • G Halliday M Hely W Reid J Morris The progression of pathology in longitudinally-followed patients with Parkinson’s disease Acta Neuropathol 115 2008 409 415
    • (2008) Acta Neuropathol , vol.115 , pp. 409-415
    • Halliday, G1    Hely, M2    Reid, W3    Morris, J4
  • 75
    • 20544468414 scopus 로고    scopus 로고
    • Nonmotor complications in Parkinson’s disease
    • CH Adler Nonmotor complications in Parkinson’s disease Mov Disord 20 suppl 11 2005 23 29
    • (2005) Mov Disord , vol.20 , Issue.suppl 11 , pp. 23-29
    • Adler, CH1
  • 76
    • 32544432029 scopus 로고    scopus 로고
    • Non-motor symptoms of Parkinson’s disease: diagnosis and management
    • KR Chaudhuri DG Healy AH Schapira Non-motor symptoms of Parkinson’s disease: diagnosis and management Lancet Neurol 5 2006 235 245
    • (2006) Lancet Neurol , vol.5 , pp. 235-245
    • Chaudhuri, KR1    Healy, DG2    Schapira, AH3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.