Selective silencing of Na V1.7 decreases excitability and conduction in vagal sensory neurons

Journal of Physiology

Volumn 589, Issue 23, 2011, Pages 5663-5676

  Muroi, Yukiko ^a   Ru, Fei ^a   Kollarik, Marian ^a   Canning, Brendan J ^a   Hughes, Stephen A ^b   Walsh, Stacey ^c   Sigg, Martin ^c   Carr, Michael J ^c   Undem, Bradley J ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b GLAXOSMITHKLINE   (United Kingdom)

^c GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PARVOVIRUS VECTOR; SODIUM CHANNEL NAV1.1; SODIUM CHANNEL NAV1.2; SODIUM CHANNEL NAV1.3; SODIUM CHANNEL NAV1.6; SODIUM CHANNEL NAV1.7; SODIUM CHANNEL NAV1.8; SODIUM CHANNEL NAV1.9;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISSOCIATION; ELECTROPHYSIOLOGY; GENE SILENCING; MALE; MEMBRANE STEADY POTENTIAL; NERVE CONDUCTION; NERVE EXCITABILITY; NODOSE GANGLION; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSORY NERVE CELL; SIGNAL TRANSDUCTION; SOMATOSENSORY SYSTEM; VAGUS NERVE; VAGUS REFLEX;

ACTION POTENTIALS; ANIMALS; CITRIC ACID; COUGH; DEPENDOVIRUS; GREEN FLUORESCENT PROTEINS; GUINEA PIGS; MALE; NEURONS, AFFERENT; NODOSE GANGLION; PATCH-CLAMP TECHNIQUES; RNA, SMALL INTERFERING; SENSORY RECEPTOR CELLS; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS; TETRODOTOXIN; TRANSDUCTION, GENETIC;

EID: 82455167007     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2011.215384     Document Type: Article

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