Experimental and modeling study of Na+ current heterogeneity in rat nodose neurons and its impact on neuronal discharge

Journal of Neurophysiology

Volumn 78, Issue 6, 1997, Pages 3198-3209

  Schild, J H ^a,c   Kunze, D L ^b  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b METROHEALTH MEDICAL CENTER   (United States)

^c Indiana University Purdue University Indianapolis   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SODIUM ION; TETRODOTOXIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; NERVE CELL EXCITABILITY; NERVE POTENTIAL; NEWBORN; NODOSE GANGLION; NONHUMAN; PRIORITY JOURNAL; RAT; SODIUM CURRENT; SODIUM TRANSPORT; TRANSPORT KINETICS;

EID: 0031425168     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.1997.78.6.3198     Document Type: Article

References (23)

1. AKOPIAN, A., ABSON, N., AND WOOD, J. Molecular genetic approaches to nociceptor development and function. Trends Neurosci. 19: 240-246, 1996.
2. Bossu, J. AND FELTZ, A. Patch-clamp study of the tetrodotoxin-resistant sodium currents in group C sensory neurons. Neursci. Lett 54: 241-246 1984.
3. CAFFREY, J., ENG, D., BLACK, J., WAXMAN, S., AND KOCSIS, J. Three types of sodium channels in adult rat dorsal root ganglion neurons. Brain Res. 592: 283-297, 1992.
4. ELLIOTT, A. AND ELLIOTT, J. Characteristics of TTX-sensitive and TTX-resistant sodium currents in small cells from adult dorsal root ganglia. J. Physiol. (Lond.) 463: 39-56, 1993.
5. + current in nociceptors. Proc. Natl. Acad. Sci. USA 93: 1108-1112, 1996.
6. HASSARD, B. Bifurcations of periodic solutions of the Hodgkin-Huxley model for the squid giant axon. J. Theor. Biol. 71: 401-420, 1978.
7. IKEDA, S. AND SCHOFIELD, G. Tetrodotoxin-resistant sodium current of rat nodose neurones: monovalent cation selectivity and divalent cation block. J. Physiol. (Lond.) 389: 255-270, 1987.
8. + currents of accurately isolated adult rat nodose ganglion cells. J. Neurophysiol. 55: 527-539, 1986.
9. LEAL-CARDOSO, H., KOSCHORKE, G., TAYLOR, G., AND WEINREICH, D. Electrophysiological properties and chemosensitivity of acutely isolated nodose ganglion neurons of the rabbit. J. Auton. Nerv. Syst. 45: 29-39, 1993.
10. NOWYCKY, M. Voltage-gated ion channels in dorsal root ganglion neurons. In: Sensory Neurons: Diversity, Development and Plasticity, edited by S. Scott. New York: Oxford Press, 1992, vol. 1, chapt. 5, p. 97-115.
11. + channels in neurons of the rat dorsal root ganglia. Brain Rese. 65: 93-100, 1992.
12. + channels in rat dorsal root ganglia. J. Physiol. (Lond.) 466: 9-37, 1993.
13. PEARCE, R. AND DUCHEN, M. Differential expression of membrane currents in dissociated mouse primary sensory neurons. Neuroscience 63: 1041 -1056, 1994.
14. RIZZO, M., KOCSIS, J., AND WAXMAN, S. Slow sodium conductances of dorsal root ganglion neurons: interneuronal homogeneity and interneuronal heterogeneity. J. Neurophysiol. 72: 2796-2815, 1994.
15. + currents in cutaneous afferent dorsal root ganglion neurons following axotomy. Neurobiol. Dis. 2: 87-96, 1995.
16. ROY, M. AND NARAHASHI, T. Differential properties of tetrodotoxin-senstivie and tetrodotoxin-resistant sodium channels in rat dorsal root ganglion neurons. J. Neurosci. 12: 2104-2111, 1992.
17. ROY, M., REUVENY, E., AND NARAHASHI, T. Single-channel analysis of tetrodotoxin-sensitive and tetrodotoxin-resistant sodium channels in rat dorsal root ganglion neurons. Brain Res. 650: 341-346, 1994.
18. SCHEUER, T. Structure and function of voltage-gated sodium channels: Regulation by phosphorylation. Biochem. Soc. Trans. 22: 479-482, 1994.
19. SCHILD, J., CLARK, J., HAY, M., MENDELOWITZ, D., ANDRESEN, M., AND KUNZE, D. A- and C-type nodose sensory neurons: model interpretations of dynamic discharge characteristics. J. Neurophysiol. 71: 2338-2358, 1994.
20. STANSFELD, C. AND WALLIS, D. Properties of visceral primary afferent neurones in the nodose ganglion of the rabbit. J. Neurophysiol. 54: 245-260, 1985.
21. VILLIERE, V. AND MCLACHLAN, E. Electrophysiological properties of neurons in intact rat dorsal root ganglia classified by conduction velocity and action potential duration. J. Neurophysiol. 76: 1924-1941, 1996.
22. WALL, P. AND DEVOR, M. Sensory afferent impulses originate from dorsal root ganglia as well as from the periphery in normal and nerver injured rats. Pain 17: 321-339, 1983.
23. YOSHIDA, S. Tetrodotoxin-resistant sodium channels. Cell. Mol. Neurobiol. 14: 227-244, 1994.