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Volumn 17, Issue 3, 1997, Pages 234-246

Impaired induction of the apoptosis-protective protein Bcl-x(L) in activated PBMC from asymptomatic HIV-infected individuals

Author keywords

apoptosis; cell survival genes; costimulatory molecules; HIV AIDS

Indexed keywords

CD4 ANTIGEN; POKEWEED MITOGEN; PROTEIN BCL 2;

EID: 8244225990     PISSN: 02719142     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1027310612323     Document Type: Article
Times cited : (19)

References (61)
  • 3
    • 0029034517 scopus 로고
    • Analysis of apoptosis in lymph nodes of HIV-infected persons. Intensity of apoptosis correlates with the general state of activation of the lymphoid tissue and not with stage of disease or viral burden
    • Muro-Cacho C, Pantaleo G, Fauci AS: Analysis of apoptosis in lymph nodes of HIV-infected persons. Intensity of apoptosis correlates with the general state of activation of the lymphoid tissue and not with stage of disease or viral burden. J Immunol 154:5555-5566, 1995
    • (1995) J Immunol , vol.154 , pp. 5555-5566
    • Muro-Cacho, C.1    Pantaleo, G.2    Fauci, A.S.3
  • 4
    • 0027497028 scopus 로고
    • Accelerated apoptosis in peripheral blood mononuclear cells (PBMCs) from human immunodeficiency virus type-1 infected patients and in CD4 cross-linked PBMCs from normal individuals
    • Oyaizu N, McCloskey TW, Coronesi M, Chirmule N, Kalyanaraman VS, Pahwa S: Accelerated apoptosis in peripheral blood mononuclear cells (PBMCs) from human immunodeficiency virus type-1 infected patients and in CD4 cross-linked PBMCs from normal individuals. Blood 82:3392-3400, 1993
    • (1993) Blood , vol.82 , pp. 3392-3400
    • Oyaizu, N.1    McCloskey, T.W.2    Coronesi, M.3    Chirmule, N.4    Kalyanaraman, V.S.5    Pahwa, S.6
  • 5
    • 0024398164 scopus 로고
    • Activation-driven T cell death. I. Requirements for de novo transcription and translation and association with genome fragmentation
    • Ucker DS, Ashwell JD, Nickas G: Activation-driven T cell death. I. Requirements for de novo transcription and translation and association with genome fragmentation. J Immunol 143:3461-3469, 1989
    • (1989) J Immunol , vol.143 , pp. 3461-3469
    • Ucker, D.S.1    Ashwell, J.D.2    Nickas, G.3
  • 6
    • 0028020169 scopus 로고
    • Analysis of lymphocyte cell death and apoptosis in HIV-2-infected patients
    • Jaleco AC, Covas MJ, Victorino R: Analysis of lymphocyte cell death and apoptosis in HIV-2-infected patients. Clin Exp Immunol 98:185-189, 1994
    • (1994) Clin Exp Immunol , vol.98 , pp. 185-189
    • Jaleco, A.C.1    Covas, M.J.2    Victorino, R.3
  • 7
    • 0027613369 scopus 로고
    • Direct and indirect mechanisms mediating apoptosis during HIV infection: Contribution to in vivo CD4 T cell depletion
    • Gougeon ML, Laurent CA, Hovanessian AG, Montagnier L: Direct and indirect mechanisms mediating apoptosis during HIV infection: Contribution to in vivo CD4 T cell depletion. Semin Immunol 5:187-194, 1993
    • (1993) Semin Immunol , vol.5 , pp. 187-194
    • Gougeon, M.L.1    Laurent, C.A.2    Hovanessian, A.G.3    Montagnier, L.4
  • 11
    • 0028970284 scopus 로고
    • HIV-1-induced thymocyte depletion is associated with indirect cytopathogenicity and infection of progenitor cells in vivo
    • Su L, Kaneshima H, Bonyhadi M, Salimi S, Kraft D, Rabin L, McCune JM: HIV-1-induced thymocyte depletion is associated with indirect cytopathogenicity and infection of progenitor cells in vivo. Immunity 2:25-36, 1995
    • (1995) Immunity , vol.2 , pp. 25-36
    • Su, L.1    Kaneshima, H.2    Bonyhadi, M.3    Salimi, S.4    Kraft, D.5    Rabin, L.6    McCune, J.M.7
  • 12
    • 0029062573 scopus 로고
    • Induction of apoptosis in uninfected lymphocytes by HIV-1 Tat protein
    • Li CJ, Friedman DJ, Wang C, Metelev V, Pardee A: Induction of apoptosis in uninfected lymphocytes by HIV-1 Tat protein. Science 268:429-431, 1995
    • (1995) Science , vol.268 , pp. 429-431
    • Li, C.J.1    Friedman, D.J.2    Wang, C.3    Metelev, V.4    Pardee, A.5
  • 14
    • 0029153922 scopus 로고
    • + blood lymphocytes are rapidly killed in vitro by contact with autologous human immunodeficiency virus-infected cells
    • + blood lymphocytes are rapidly killed in vitro by contact with autologous human immunodeficiency virus-infected cells. Proc Natl Acad Sci USA 92:7312-7316, 1995
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 7312-7316
    • Nardelli, B.1    Gonzalez, C.J.2    Schlechter, M.3    Valentine, F.T.4
  • 16
    • 0027513268 scopus 로고
    • Apoptosis
    • Cohen JJ: Apoptosis. Immunol Today 14:126-130, 1993
    • (1993) Immunol Today , vol.14 , pp. 126-130
    • Cohen, J.J.1
  • 18
    • 0029136149 scopus 로고
    • Apoptosis in viral infections
    • Razvi ES, Welsh RM: Apoptosis in viral infections. Adv Virus Res 45:1-60, 1995
    • (1995) Adv Virus Res , vol.45 , pp. 1-60
    • Razvi, E.S.1    Welsh, R.M.2
  • 23
    • 0027161158 scopus 로고
    • Effect of bcl-2 on Fas antigen-mediated cell death
    • Itoh N, Tsujimoto Y, Nagata S: Effect of bcl-2 on Fas antigen-mediated cell death. J Immunol 151:621-627, 1993
    • (1993) J Immunol , vol.151 , pp. 621-627
    • Itoh, N.1    Tsujimoto, Y.2    Nagata, S.3
  • 24
    • 0024596722 scopus 로고
    • A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor
    • Yonehara S, Ishii A, Yonehara M: A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor. J Exp Med 169:1747-1756, 1989
    • (1989) J Exp Med , vol.169 , pp. 1747-1756
    • Yonehara, S.1    Ishii, A.2    Yonehara, M.3
  • 25
    • 0029066512 scopus 로고
    • FAP-1: A protein tyrosine phosphatase that associates with Fas
    • Sato T, Irie S, Kitada S, Reed JC: FAP-1: A protein tyrosine phosphatase that associates with Fas. Science 268:411-415, 1995
    • (1995) Science , vol.268 , pp. 411-415
    • Sato, T.1    Irie, S.2    Kitada, S.3    Reed, J.C.4
  • 26
    • 0027183703 scopus 로고
    • Activation interferes with the APO-1 pathway in mature human T cells
    • Klas C, Debatin KM, Jonker RR, Krammer PH: Activation interferes with the APO-1 pathway in mature human T cells. Int Immunol 5:625-630, 1993
    • (1993) Int Immunol , vol.5 , pp. 625-630
    • Klas, C.1    Debatin, K.M.2    Jonker, R.R.3    Krammer, P.H.4
  • 27
    • 0029048581 scopus 로고
    • Fas antigen stimulation induces marked apoptosis of T lymphocytes in human immunodeficiency virus-infected individuals
    • Katsikis PD, Wunderlich ES, Smith CA, Herzenberg LA, Herzenberg LA: Fas antigen stimulation induces marked apoptosis of T lymphocytes in human immunodeficiency virus-infected individuals. J Exp Med 181:2029-2036, 1995
    • (1995) J Exp Med , vol.181 , pp. 2029-2036
    • Katsikis, P.D.1    Wunderlich, E.S.2    Smith, C.A.3    Herzenberg, L.A.4    Herzenberg, L.A.5
  • 28
    • 9044232148 scopus 로고    scopus 로고
    • The Fas receptor in HIV infection: Expression on peripheral blood lymphocytes and role in the depletion of T cells
    • Gehri R, Sinuhe H, Steuerwald M, Nuesch R, Erb P: The Fas receptor in HIV infection: Expression on peripheral blood lymphocytes and role in the depletion of T cells. AIDS 10:9-16, 1996
    • (1996) AIDS , vol.10 , pp. 9-16
    • Gehri, R.1    Sinuhe, H.2    Steuerwald, M.3    Nuesch, R.4    Erb, P.5
  • 29
    • 8244233876 scopus 로고
    • Differential expression of bcl-2 and susceptibility to anti-fas-mediated cell death in peripheral blood lymphocytes, monocytes and neutrophils
    • Iwai K, Miyawaki T, Takizawa T, Konno A, Ohta K, Yachie A, Seki H, Taniguchi N: Differential expression of bcl-2 and susceptibility to anti-fas-mediated cell death in peripheral blood lymphocytes, monocytes and neutrophils. Adv Virus Res 84:1202-1208, 1994
    • (1994) Adv Virus Res , vol.84 , pp. 1202-1208
    • Iwai, K.1    Miyawaki, T.2    Takizawa, T.3    Konno, A.4    Ohta, K.5    Yachie, A.6    Seki, H.7    Taniguchi, N.8
  • 30
    • 0028226620 scopus 로고
    • Inverse expression of bcl-2 protein and Fas antigen in lymphoblasts in peripheral lymph nodes and activated peripheral blood T and B lymphocytes
    • Yoshino T, Kondo E, Cao L, Takahashi K, Hayashi K, Nomura S, Akagi T: Inverse expression of bcl-2 protein and Fas antigen in lymphoblasts in peripheral lymph nodes and activated peripheral blood T and B lymphocytes. Blood 83:1856-1861, 1994
    • (1994) Blood , vol.83 , pp. 1856-1861
    • Yoshino, T.1    Kondo, E.2    Cao, L.3    Takahashi, K.4    Hayashi, K.5    Nomura, S.6    Akagi, T.7
  • 31
    • 0028982230 scopus 로고
    • Bcl-xL rescues WEHI 231 B lymphocytes from oxidant-mediated death following diverse apoptotic stimuli
    • Fang W, Rivard JJ, Ganser JA, Le BT, Nath KA, Mueller DL, Behrens TW: Bcl-xL rescues WEHI 231 B lymphocytes from oxidant-mediated death following diverse apoptotic stimuli. J Immunol 155:66-75, 1995
    • (1995) J Immunol , vol.155 , pp. 66-75
    • Fang, W.1    Rivard, J.J.2    Ganser, J.A.3    Le, B.T.4    Nath, K.A.5    Mueller, D.L.6    Behrens, T.W.7
  • 33
    • 0025255538 scopus 로고
    • Deregulated Bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines
    • Nunez G, London L, Hockenbery D, Alexander M, McKearn JP, Korsmeyer SJ: Deregulated Bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines. J Immunol 144:3602-3610, 1990
    • (1990) J Immunol , vol.144 , pp. 3602-3610
    • Nunez, G.1    London, L.2    Hockenbery, D.3    Alexander, M.4    McKearn, J.P.5    Korsmeyer, S.J.6
  • 34
    • 0028206341 scopus 로고
    • BH1 and BH2 domains of Bcl-2 are required tor inhibition of apoptosis and heterodimerization with Bax
    • Yin XM, Oltval ZN, Korsmeyer SJ: BH1 and BH2 domains of Bcl-2 are required tor inhibition of apoptosis and heterodimerization with Bax. Nature 369:321-323, 1994
    • (1994) Nature , vol.369 , pp. 321-323
    • Yin, X.M.1    Oltval, Z.N.2    Korsmeyer, S.J.3
  • 35
    • 0027427492 scopus 로고
    • Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair
    • Veis DJ, Sorenson CM, Shutter JR, Korsmeyer SJ: Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair. Cell 75:229-240, 1993
    • (1993) Cell , vol.75 , pp. 229-240
    • Veis, D.J.1    Sorenson, C.M.2    Shutter, J.R.3    Korsmeyer, S.J.4
  • 37
    • 0026655474 scopus 로고
    • Bcl-2 initiates a new category of oncogenes: Regulators of cell death
    • Korsmeyer SJ: Bcl-2 initiates a new category of oncogenes: Regulators of cell death. Blood 80:879-886, 1992
    • (1992) Blood , vol.80 , pp. 879-886
    • Korsmeyer, S.J.1
  • 40
    • 0029091387 scopus 로고
    • Induction of bcl-x by CD40 engagement rescues sIg-induced apoptosis in murine B cells
    • Wang Z, Karras JG, Howard RG, Rothstein TL: Induction of bcl-x by CD40 engagement rescues sIg-induced apoptosis in murine B cells. J Immunol 155:3722-3725, 1995
    • (1995) J Immunol , vol.155 , pp. 3722-3725
    • Wang, Z.1    Karras, J.G.2    Howard, R.G.3    Rothstein, T.L.4
  • 41
    • 0028970662 scopus 로고
    • bcl-xL displays a restricted expression during thymic development and inhibits multiple forms of apoptosis but not clonal deletion
    • Grillot DAG, Merino R, Nunez G: bcl-xL displays a restricted expression during thymic development and inhibits multiple forms of apoptosis but not clonal deletion. J Exp Med 182:1973-1983, 1995
    • (1995) J Exp Med , vol.182 , pp. 1973-1983
    • Grillot, D.A.G.1    Merino, R.2    Nunez, G.3
  • 42
    • 0029670773 scopus 로고    scopus 로고
    • bcl-x exhibits regulated expression during B cell development and activation and modulates lymphocyte survival in transgenic mice
    • Grillot DAG, Merino R, Pena JC, Fanslow WC, Finkelman FD, Thompson CB, Nunez G: bcl-x exhibits regulated expression during B cell development and activation and modulates lymphocyte survival in transgenic mice. J Exp Med 183:381-391, 1996
    • (1996) J Exp Med , vol.183 , pp. 381-391
    • Grillot, D.A.G.1    Merino, R.2    Pena, J.C.3    Fanslow, W.C.4    Finkelman, F.D.5    Thompson, C.B.6    Nunez, G.7
  • 44
    • 0030293533 scopus 로고    scopus 로고
    • IL-2 rescues in vitro lymphocyte apoptosis in patients with HIV infection
    • Adachi Y, Oyaizu N, Than S, McCloskey T, Pahwa S: IL-2 rescues in vitro lymphocyte apoptosis in patients with HIV infection. J Immunol 157:4184-4193, 1996
    • (1996) J Immunol , vol.157 , pp. 4184-4193
    • Adachi, Y.1    Oyaizu, N.2    Than, S.3    McCloskey, T.4    Pahwa, S.5
  • 45
    • 0022629697 scopus 로고
    • The Walter Reed staging classification for HTLV-III/LAV infection
    • Redfield RR, Wright DC, Tramont ET: The Walter Reed staging classification for HTLV-III/LAV infection. N Engl J Med 314: 131-132, 1986
    • (1986) N Engl J Med , vol.314 , pp. 131-132
    • Redfield, R.R.1    Wright, D.C.2    Tramont, E.T.3
  • 46
    • 0028850465 scopus 로고
    • Human naive and memory T lymphocytes differ in telomeric length and replicative potential
    • Weng N-P, Levine B, June CH, Hodes RJ: Human naive and memory T lymphocytes differ in telomeric length and replicative potential. Proc Natl Acad Sci USA 92:11091-11094, 1995
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 11091-11094
    • Weng, N.-P.1    Levine, B.2    June, C.H.3    Hodes, R.J.4
  • 47
    • 0026515679 scopus 로고
    • Fixation of mammalian cells for flow cytometric evaluation of DNA content and nuclear immunofluorescence
    • Schimenti KJ, Jacobberger JW: Fixation of mammalian cells for flow cytometric evaluation of DNA content and nuclear immunofluorescence. Cytometry 13:48-59, 1992
    • (1992) Cytometry , vol.13 , pp. 48-59
    • Schimenti, K.J.1    Jacobberger, J.W.2
  • 49
    • 0028290446 scopus 로고
    • Identification of immunosuppressant-induced apoptosis in a murine B-cell line and its prevention by bcl-x but not bcl-2
    • Gottschalk AR, Boise LH, Thompson CB, Quintans J: Identification of immunosuppressant-induced apoptosis in a murine B-cell line and its prevention by bcl-x but not bcl-2. Proc Natl Acad Sci USA 91:7350-7354, 1994
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 7350-7354
    • Gottschalk, A.R.1    Boise, L.H.2    Thompson, C.B.3    Quintans, J.4
  • 50
    • 0027269557 scopus 로고
    • Detection of DNA strand breaks in individual apoptotic cells by the in situ terminal deoxynucleotidyl transferase and nick translational assay
    • Gorczcan W, Gong J, Darzynkiewicz Z: Detection of DNA strand breaks in individual apoptotic cells by the in situ terminal deoxynucleotidyl transferase and nick translational assay. Cancer Res 53:1945-1948, 1993
    • (1993) Cancer Res , vol.53 , pp. 1945-1948
    • Gorczcan, W.1    Gong, J.2    Darzynkiewicz, Z.3
  • 53
    • 0029046693 scopus 로고
    • Expression of Bcl-2, Bcl-x, and Bax after T cell activation and IL-2 withdrawal
    • Broome HE, Dargan CM, Krajewski S, Reed JC: Expression of Bcl-2, Bcl-x, and Bax after T cell activation and IL-2 withdrawal. J Immunol 155:2311-2317, 1995
    • (1995) J Immunol , vol.155 , pp. 2311-2317
    • Broome, H.E.1    Dargan, C.M.2    Krajewski, S.3    Reed, J.C.4
  • 54
    • 0028892789 scopus 로고
    • Immunoblot analysis of cellular expression of Bcl-2 family proteins, Bcl-2, Bax, Bcl-x and Mcl-1 in human peripheral blood and lymphoid tissues
    • Ohta K, Kazuyuki I, Kasahara Y, Taniguchi N, Krajewski S, Reed JC, Miyawaki T: Immunoblot analysis of cellular expression of Bcl-2 family proteins, Bcl-2, Bax, Bcl-x and Mcl-1 in human peripheral blood and lymphoid tissues. Int Immunol 7:1817-1825, 1995
    • (1995) Int Immunol , vol.7 , pp. 1817-1825
    • Ohta, K.1    Kazuyuki, I.2    Kasahara, Y.3    Taniguchi, N.4    Krajewski, S.5    Reed, J.C.6    Miyawaki, T.7
  • 55
    • 0028080739 scopus 로고
    • The CD69 receptor: A multipurpose cell-surface trigger for hematopoietic cells
    • Testi R, D'Ambrosio R, De Maria R, Santoni A: The CD69 receptor: A multipurpose cell-surface trigger for hematopoietic cells. Immunol Today 15:475-483, 1994
    • (1994) Immunol Today , vol.15 , pp. 475-483
    • Testi, R.1    D'Ambrosio, R.2    De Maria, R.3    Santoni, A.4
  • 56
    • 0030006733 scopus 로고    scopus 로고
    • CD28 costimulation prevents cell death during primary T cell activation
    • Noel PJ, Boise LH, Green JM, Thompson GB: CD28 costimulation prevents cell death during primary T cell activation. J Immunol 157:636-642, 1996
    • (1996) J Immunol , vol.157 , pp. 636-642
    • Noel, P.J.1    Boise, L.H.2    Green, J.M.3    Thompson, G.B.4
  • 57
    • 0029961719 scopus 로고    scopus 로고
    • Die and let live: Eliminating dangerous lymphocytes
    • Abbas AK: Die and let live: eliminating dangerous lymphocytes. Cell 84:655-657, 1996
    • (1996) Cell , vol.84 , pp. 655-657
    • Abbas, A.K.1
  • 58
    • 0029876593 scopus 로고    scopus 로고
    • CD40-mediated signaling in B cells balancing cell survival, growth and death
    • Kehry MR: CD40-mediated signaling in B cells balancing cell survival, growth and death. J Immunol 156:2345-2348, 1996
    • (1996) J Immunol , vol.156 , pp. 2345-2348
    • Kehry, M.R.1
  • 60
    • 0030293443 scopus 로고    scopus 로고
    • CD28/B7 interactions deliver a unique signal to naive T cells that regulate cell survival but not early proliferation
    • Sperling AI, Auger JA, Ehst BD, Rulifson IC, Thompson CB, Bluestone JA: CD28/B7 interactions deliver a unique signal to naive T cells that regulate cell survival but not early proliferation. J Immunol 157:3909-3917, 1996
    • (1996) J Immunol , vol.157 , pp. 3909-3917
    • Sperling, A.I.1    Auger, J.A.2    Ehst, B.D.3    Rulifson, I.C.4    Thompson, C.B.5    Bluestone, J.A.6


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