An orthotopic, postsurgical model of luciferase transfected murine osteosarcoma with spontaneous metastasis

Clinical and Experimental Metastasis

Volumn 27, Issue 3, 2010, Pages 151-160

  Sottnik, Joseph L ^a   Duval, Dawn L ^a   J Ehrhart, E ^a   Thamm, Douglas H ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

Bone; C3H; Dunn; Mouse; Surgery; Syngeneic

Indexed keywords

CARBOPLATIN; DOXORUBICIN; FIREFLY LUCIFERASE;

AMPUTATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; C3H MOUSE; CANCER MODEL; CONTROLLED STUDY; DISEASE FREE SURVIVAL; GENETIC TRANSFECTION; IMMUNOCOMPETENCE; METASTASIS; MINIMAL RESIDUAL DISEASE; MOUSE; NONHUMAN; ORTHOTOPIC TRANSPLANTATION; OSTEOLYSIS; OSTEOSARCOMA; OVERALL SURVIVAL; POSTOPERATIVE PERIOD; SOFT TISSUE METASTASIS; TIBIA; TISSUE ENGINEERING;

ANIMALS; BONE NEOPLASMS; CARBOPLATIN; CELL LINE, TUMOR; DISEASE MODELS, ANIMAL; DOXORUBICIN; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; LUCIFERASES; MICE; MICE, INBRED C3H; NEOPLASM METASTASIS; NEOPLASM TRANSPLANTATION; OSTEOBLASTS; OSTEOSARCOMA; SURVIVAL ANALYSIS; TIBIA; TRANSFECTION;

EID: 77950861307     PISSN: 02620898     EISSN: 15737276     Source Type: Journal    
DOI: 10.1007/s10585-010-9318-z     Document Type: Article

References (46)

1. F Mueller B Fuchs B Kaser-Hotz 2007 Comparative biology of human and canine osteosarcoma Anticancer Res 27 1A 155 164 1:CAS:528:DC%2BD2sXjs1Wns70%3D 17352227
2. C Khanna 2008 Novel targets with potential therapeutic applications in osteosarcoma Curr Oncol Rep 10 4 350 358 10.1007/s11912-008-0054-3 1:CAS:528:DC%2BD1cXhtFems7bM 18778562
3. SS Bielack D Carrle J Hardes, et al. 2008 Bone tumors in adolescents and young adults Curr Treat Options Oncol 9 1 67 80 10.1007/s11864-008-0057-1 18449804
4. O Berlin D Samid R Donthineni-Rao, et al. 1993 Development of a novel spontaneous metastasis model of human osteosarcoma transplanted orthotopically into bone of athymic mice Cancer Res 53 20 4890 4895 1:STN:280: DyaK2c%2Fgs1aqsg%3D%3D 8402677
5. Comstock KE, Hall CL, Daignault S et al. (2009) A bioluminescent orthotopic mouse model of human osteosarcoma that allows sensitive and rapid evaluation of new therapeutic agents In vivo. In vivo (Athens, Greece) 23(5): 661-668
6. S Crnalic I Hakansson L Boquist, et al. 1997 A novel spontaneous metastasis model of human osteosarcoma developed using orthotopic transplantation of intact tumor tissue into tibia of nude mice Clin Exp Metastasis 15 2 164 172 10.1023/A:1018456911823 1:STN:280:DyaK2s3hs1WjsQ%3D%3D 9062393 (Pubitemid 27157819)
7. CR Dass PF Choong 2007 Zoledronic acid inhibits osteosarcoma growth in an orthotopic model Mol Cancer Ther 6 12 Pt 1 3263 3270 10.1158/1535-7163.MCT-07- 0546 1:CAS:528:DC%2BD2sXhsVCjsrrN 18089720
8. CR Dass ET Ek PF Choong 2007 Human xenograft osteosarcoma models with spontaneous metastasis in mice: clinical relevance and applicability for drug testing J Cancer Res Clin Oncol 133 3 193 198 10.1007/s00432-006-0157-x 17031670 (Pubitemid 46144095)
9. CR Dass ET Ek KG Contreras, et al. 2006 A novel orthotopic murine model provides insights into cellular and molecular characteristics contributing to human osteosarcoma Clin Exp Metastasis 23 7-8 367 380 17187230
10. C Khanna J Khan P Nguyen, et al. 2001 Metastasis-associated differences in gene expression in a murine model of osteosarcoma Cancer Res 61 9 3750 3759 1:CAS:528:DC%2BD3MXjsFCgurc%3D 11325848
11. C Khanna J Prehn C Yeung, et al. 2000 An orthotopic model of murine osteosarcoma with clonally related variants differing in pulmonary metastatic potential Clin Exp Metastasis 18 3 261 271 10.1023/A:1006767007547 1:CAS:528:DC%2BD3MXjtFKntr0%3D 11315100 (Pubitemid 32269996)
12. JW Lisle JY Choi JA Horton, et al. 2008 Metastatic osteosarcoma gene expression differs in vitro and in vivo Clinical orthopaedics and related research 466 9 2071 2080 10.1007/s11999-008-0309-1 18516656
13. HH Luu Q Kang JK Park, et al. 2005 An orthotopic model of human osteosarcoma growth and spontaneous pulmonary metastasis Clin Exp Metastasis 22 4 319 329 10.1007/s10585-005-0365-9 16170668 (Pubitemid 41374288)
14. S Miretti I Roato R Taulli, et al. 2008 A mouse model of pulmonary metastasis from spontaneous osteosarcoma monitored in vivo by Luciferase imaging PloS one 3 3 e1828 10.1371/journal.pone.0001828 18350164 (Pubitemid 351936289)
15. J Yuan C Ossendorf JP Szatkowski, et al. 2009 Osteoblastic and osteolytic human osteosarcomas can be studied with a new xenograft mouse model producing spontaneous metastases Cancer Invest 27 4 435 442 10.1080/07357900802491477 19212826
16. K Koto N Horie S Kimura, et al. 2009 Clinically relevant dose of zoledronic acid inhibits spontaneous lung metastasis in a murine osteosarcoma model Cancer Lett 274 2 271 278 10.1016/j.canlet.2008.09.026 1:CAS:528:DC%2BD1MXns12qsw%3D%3D 18986762
17. T Asai T Ueda K Itoh, et al. 1998 Establishment and characterization of a murine osteosarcoma cell line (LM8) with high metastatic potential to the lung Int J Cancer 76 3 418 422 10.1002/(SICI)1097-0215(19980504)76:3<418::AID- IJC21>3.0.CO;2-5 1:CAS:528:DyaK1cXjtVOqs7c%3D 9579581 (Pubitemid 28282943)
18. O De Wever M Mareel 2003 Role of tissue stroma in cancer cell invasion J Pathol 200 4 429 447 10.1002/path.1398 12845611 (Pubitemid 36818244)
19. C Khanna K Hunter 2005 Modeling metastasis in vivo Carcinogenesis 26 3 513 523 10.1093/carcin/bgh261 1:CAS:528:DC%2BD2MXhslSrsrw%3D 15358632 (Pubitemid 41214139)
20. N Yamada M Hata H Ohyama, et al. 2009 Immunotherapy with interleukin-18 in combination with preoperative chemotherapy with ifosfamide effectively inhibits postoperative progression of pulmonary metastases in a mouse osteosarcoma model Tumour Biol 30 4 176 184 10.1159/000236410 1:CAS:528:DC%2BD1MXht1OqsLrF 19738413
21. CJ Bruns MT Harbison H Kuniyasu, et al. 1999 In vivo selection and characterization of metastatic variants from human pancreatic adenocarcinoma by using orthotopic implantation in nude mice Neoplasia 1 1 50 62 10.1038/sj.neo.7900005 1:CAS:528:DC%2BD3cXhtFOrs7Y%3D 10935470 (New York, NY)
22. CA Pettaway S Pathak G Greene, et al. 1996 Selection of highly metastatic variants of different human prostatic carcinomas using orthotopic implantation in nude mice Clin Cancer Res 2 9 1627 1636 1:STN:280:DyaK1M%2FjsFWqsg%3D%3D 9816342
23. IJ Fidler C Wilmanns A Staroselsky, et al. 1994 Modulation of tumor cell response to chemotherapy by the organ environment Cancer Metastasis Rev 13 2 209 222 10.1007/BF00689637 1:STN:280:DyaK2M%2Fgsl2ltg%3D%3D 7923551 (Pubitemid 24220006)
24. C Wilmanns D Fan CA O'Brian, et al. 1992 Orthotopic and ectopic organ environments differentially influence the sensitivity of murine colon carcinoma cells to doxorubicin and 5-fluorouracil Int J Cancer 52 1 98 104 10.1002/ijc.2910520118 1:CAS:528:DyaK3sXhsF2guw%3D%3D 1500231
25. M Paoloni C Khanna 2008 Translation of new cancer treatments from pet dogs to humans Nat Rev 8 2 147 156 1:CAS:528:DC%2BD1cXhtVGhsLw%3D
26. HT Ta CR Dass PF Choong, et al. 2009 Osteosarcoma treatment: state of the art Cancer Metastasis Rev 28 1-2 247 263 10.1007/s10555-009-9186-7 19214708
27. KA Keyes L Mann B Teicher, et al. 2003 Site-dependent angiogenic cytokine production in human tumor xenografts Cytokine 21 2 98 104 10.1016/S1043- 4666(03)00015-2 1:CAS:528:DC%2BD3sXisFSnt7Y%3D 12670449 (Pubitemid 36369396)
28. F Burke 1999 Cytokines (IFNs, TNF-alpha, IL-2 and IL-12) and animal models of cancer. Cytokines Cell Mol Ther 5 1 51 61 1:CAS:528:DyaK1MXivFWjsbw%3D
29. A Garofalo RG Chirivi E Scanziani, et al. 1993 Comparative study on the metastatic behavior of human tumors in nude, beige/nude/xid and severe combined immunodeficient mice Invasion Metastasis 13 2 82 91 1:STN:280: DyaK2c%2FktF2htQ%3D%3D 8225855
30. BM Mueller RA Reisfeld 1991 Potential of the scid mouse as a host for human tumors Cancer Metastasis Rev 10 3 193 200 10.1007/BF00050791 1:STN:280:DyaK387htVyruw%3D%3D 1764764
31. P Anderson L Kopp N Anderson, et al. 2008 Novel bone cancer drugs: investigational agents and control paradigms for primary bone sarcomas (Ewing's sarcoma and osteosarcoma) Expert Opin Investig Drugs 17 11 1703 1715 10.1517/13543784.17.11.1703 1:CAS:528:DC%2BD1cXht1CmsbnN 18922107
32. SW Dow LG Fradkin DH Liggitt, et al. 1999 Lipid-DNA complexes induce potent activation of innate immune responses and antitumor activity when administered intravenously J Immunol 163 3 1552 1561 1:CAS:528: DyaK1MXkslOgsLk%3D 10415059
33. Hafeman S, London C, Elmslie R et al. (2009) Evaluation of liposomal clodronate for treatment of malignant histiocytosis in dogs. Cancer Immunol Immunother
34. RJ Higgins M McKisic PJ Dickinson, et al. 2004 Growth inhibition of an orthotopic glioblastoma in immunocompetent mice by cationic lipid-DNA complexes Cancer Immunol Immunother 53 4 338 344 10.1007/s00262-003-0447-y 1:CAS:528:DC%2BD2cXisVWhtbs%3D 14618278 (Pubitemid 38392311)
35. ID Kurzman EG MacEwen RC Rosenthal, et al. 1995 Adjuvant therapy for osteosarcoma in dogs: results of randomized clinical trials using combined liposome-encapsulated muramyl tripeptide and cisplatin Clin Cancer Res 1 12 1595 1601 1:CAS:528:DyaK28XmvVWhtQ%3D%3D 9815961
36. K Mori K Ando D Heymann 2008 Liposomal muramyl tripeptide phosphatidyl ethanolamine: a safe and effective agent against osteosarcoma pulmonary metastases Expert Rev Anticancer Ther 8 2 151 159 10.1586/14737140.8.2.151 1:CAS:528:DC%2BD1cXitlOgtrY%3D 18279055 (Pubitemid 351385905)
37. SJ Patel JW Lynch Jr T Johnson, et al. 2002 Dose-intense ifosfamide/doxorubicin/cisplatin based chemotherapy for osteosarcoma in adults Am J Clin Oncol 25 5 489 495 10.1097/00000421-200210000-00014 12393991 (Pubitemid 35154956)
38. PA Meyers R Gorlick 1997 Osteosarcoma Pediatr Clin North Am 44 4 973 989 10.1016/S0031-3955(05)70540-X 1:STN:280:DyaK2svjt1eqtA%3D%3D 9286295 (Pubitemid 27368674)
39. AC Chiang J Massague 2008 Molecular basis of metastasis N Engl J Med 359 26 2814 2823 10.1056/NEJMra0805239 1:CAS:528:DC%2BD1cXhsFCnt7bF 19109576
40. JA Joyce JW Pollard 2009 Microenvironmental regulation of metastasis Nat Rev 9 4 239 252 1:CAS:528:DC%2BD1MXivFCjsLg%3D
41. K Krishnan C Khanna LJ Helman 2006 The molecular biology of pulmonary metastasis Thorac Surg Clin 16 2 115 124 10.1016/j.thorsurg.2005.12.003 16805200 (Pubitemid 43728424)
42. M Mendoza C Khanna 2009 Revisiting the seed and soil in cancer metastasis Int J Biochem Cell Biol 41 7 1452 1462 10.1016/j.biocel.2009.01.015 1:CAS:528:DC%2BD1MXktFerur4%3D 19401145
43. OS Bruland H Hoifodt G Saeter, et al. 2005 Hematogenous micrometastases in osteosarcoma patients Clin Cancer Res 11 13 4666 4673 10.1158/1078-0432.CCR- 05-0165 1:CAS:528:DC%2BD2MXlvVGht70%3D 16000559 (Pubitemid 41568166)
44. CR Dass PF Choong 2007 GFP expression alters osteosarcoma cell biology DNA Cell Biol 26 8 599 601 10.1089/dna.2006.0531 1:CAS:528:DC%2BD2sXoslagsLw%3D 17688411 (Pubitemid 47263206)
45. RS Kerbel 1998 What is the optimal rodent model for anti-tumor drug testing? Cancer Metastasis Rev 17 3 301 304 10.1023/A:1006152915959 10352884 (Pubitemid 29210170)
46. JE Talmadge RK Singh IJ Fidler, et al. 2007 Murine models to evaluate novel and conventional therapeutic strategies for cancer Am J Pathol 170 3 793 804 10.2353/ajpath.2007.060929 1:CAS:528:DC%2BD2sXjs1Wls78%3D 17322365 (Pubitemid 47339349)