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Volumn 124, Issue 22, 2011, Pages 3794-3799

Inhibition of connective tissue growth factor overexpression decreases growth of hepatocellular carcinoma cells in vitro and in vivo

Author keywords

Cell proliferation; Connective tissue growth factor; Hepatocellular carcinoma; siRNA

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CONNECTIVE TISSUE GROWTH FACTOR; LENTIVIRUS VECTOR; MESSENGER RNA; SHORT HAIRPIN RNA; SMALL INTERFERING RNA;

EID: 82255195473     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.0366-6999.2011.22.034     Document Type: Article
Times cited : (16)

References (34)
  • 1
    • 77953403066 scopus 로고    scopus 로고
    • Evolving therapies in the treatment of hepatocellularcarcinoma
    • Spangenberg HC, Thimme R, Blum HE. Evolving therapies in the treatment of hepatocellularcarcinoma. Biologics 2008; 2: 453-462.
    • (2008) Biologics , vol.2 , pp. 453-462
    • Spangenberg, H.C.1    Thimme, R.2    Blum, H.E.3
  • 2
    • 0035729049 scopus 로고    scopus 로고
    • Systemic treatment of hepatocellular carcinoma
    • Treiber G. Systemic treatment of hepatocellular carcinoma. Dig Dis 2001; 19: 311-323.
    • (2001) Dig Dis , vol.19 , pp. 311-323
    • Treiber, G.1
  • 4
    • 37149004184 scopus 로고    scopus 로고
    • From molecular biology to targeted therapies for hepatocellular carcinomacarcinoma: The future is now
    • Pang RW, Poon RT. From molecular biology to targeted therapies for hepatocellular carcinomacarcinoma: the future is now. Oncology 2007; 72 Suppl 1: 30-44.
    • (2007) Oncology , Issue.72 SUPPL. 1 , pp. 30-44
    • Pang, R.W.1    Poon, R.T.2
  • 5
    • 77952400159 scopus 로고    scopus 로고
    • Core signaling pathways and new therapeutic targets in pancreatic cancer
    • You L, Chen G, Zhao YP. Core signaling pathways and new therapeutic targets in pancreatic cancer. Chin Med J 2010; 123: 1210-1215.
    • (2010) Chin Med J , vol.123 , pp. 1210-1215
    • You, L.1    Chen, G.2    Zhao, Y.P.3
  • 6
    • 69249107364 scopus 로고    scopus 로고
    • Characteristic gene expression profiles in the progression from liver cirrhosis to carcinoma induced by diethylnitrosamine in a rat model
    • Liu YF, Zha BS, Zhang HL, Zhu XJ, Li YH, Zhu J, et al. Characteristic gene expression profiles in the progression from liver cirrhosis to carcinoma induced by diethylnitrosamine in a rat model. J Exp Clin Cancer Res 2009; 28: 107-123.
    • (2009) J Exp Clin Cancer Res , vol.28 , pp. 107-123
    • Liu, Y.F.1    Zha, B.S.2    Zhang, H.L.3    Zhu, X.J.4    Li, Y.H.5    Zhu, J.6
  • 7
    • 15044359781 scopus 로고    scopus 로고
    • Intergrated actions of transforming growth factor-batal and connective tissue growth factor in renal fibrosis
    • Qi W, Twigg S, Chen X, Polhill TS, Poronnik P, Gilbert RE, et al. Intergrated actions of transforming growth factor-batal and connective tissue growth factor in renal fibrosis. Am J Physio Renal Physiol 2005; 288: F800-F809.
    • (2005) Am J Physio Renal Physiol , vol.288
    • Qi, W.1    Twigg, S.2    Chen, X.3    Polhill, T.S.4    Poronnik, P.5    Gilbert, R.E.6
  • 8
    • 33845906843 scopus 로고    scopus 로고
    • All in the CCN family: Essential matricellular signaling modulators emerge from the bunker
    • Leask A, Abraham DJ. All in the CCN family: essential matricellular signaling modulators emerge from the bunker. J Cell Sci 2006; 119: 4803-4810.
    • (2006) J Cell Sci , vol.119 , pp. 4803-4810
    • Leask, A.1    Abraham, D.J.2
  • 9
    • 12144291566 scopus 로고    scopus 로고
    • Inhibition of connective tissue growth factor (CTGF/CCN2) expression decreases the survival and myogenic differentiation of human rhabdomyosarcoma cells
    • Croci S, Landuzzi L, Astolfi A, Nicoletti G, Rosolen A, Sartori F, et al. Inhibition of connective tissue growth factor (CTGF/CCN2) expression decreases the survival and myogenic differentiation of human rhabdomyosarcoma cells. Cancer Res 2004; 64: 1730-1736.
    • (2004) Cancer Res , vol.64 , pp. 1730-1736
    • Croci, S.1    Landuzzi, L.2    Astolfi, A.3    Nicoletti, G.4    Rosolen, A.5    Sartori, F.6
  • 10
    • 0035893738 scopus 로고    scopus 로고
    • Elevated levels of connective tissue growth factor, WISP-1, and CYR61 in primary breast cancers associated with more advanced features
    • Xie D, Nakachi K, Wang H, Elashoff R, Koeffler HP. Elevated levels of connective tissue growth factor, WISP-1, and CYR61 in primary breast cancers associated with more advanced features. Cancer Res 2001; 61: 8917-8923.
    • (2001) Cancer Res , vol.61 , pp. 8917-8923
    • Xie, D.1    Nakachi, K.2    Wang, H.3    Elashoff, R.4    Koeffler, H.P.5
  • 11
    • 0036787545 scopus 로고    scopus 로고
    • Neoplastic cells and proliferating endothelial cells express connective tissue growth factor (CTGF) in glioblastoma
    • Pan LH, Beppu T, Kurose A, Yamauchi K, Sugawara A, Suzuki M, et al. Neoplastic cells and proliferating endothelial cells express connective tissue growth factor (CTGF) in glioblastoma. Neurol Res 2002; 24: 677-683.
    • (2002) Neurol Res , vol.24 , pp. 677-683
    • Pan, L.H.1    Beppu, T.2    Kurose, A.3    Yamauchi, K.4    Sugawara, A.5    Suzuki, M.6
  • 12
    • 1642350329 scopus 로고    scopus 로고
    • Levels of expression of CYR61 and CTGF are prognostic for tumor progression and survival of individuals with gliomas
    • Xie D, Yin D, Wang HJ, Liu GT, Elashoff R, Black K, et al. Levels of expression of CYR61 and CTGF are prognostic for tumor progression and survival of individuals with gliomas. Clin Cancer Res 2004; 10: 2072-2081.
    • (2004) Clin Cancer Res , vol.10 , pp. 2072-2081
    • Xie, D.1    Yin, D.2    Wang, H.J.3    Liu, G.T.4    Elashoff, R.5    Black, K.6
  • 13
    • 0036548760 scopus 로고    scopus 로고
    • Connective tissue growth factor gene expression alters tumor progression in esophageal cancer
    • Koliopanos A, Friess H, di Mola FF, Tang WH, Kubulus D, Brigstock D, et al. Connective tissue growth factor gene expression alters tumor progression in esophageal cancer. World J Surg 2002; 26: 420-427.
    • (2002) World J Surg , vol.26 , pp. 420-427
    • Koliopanos, A.1    Friess, H.2    di Mola, F.F.3    Tang, W.H.4    Kubulus, D.5    Brigstock, D.6
  • 14
    • 0034306881 scopus 로고    scopus 로고
    • Expression of connective tissue growth factor in cartilaginous tumors
    • Shakunaga T, Ozaki T, Ohara N, Asaumi K, Doi T, Nishida K, et al. Expression of connective tissue growth factor in cartilaginous tumors. Cancer 2000; 89: 1466-1473.
    • (2000) Cancer , vol.89 , pp. 1466-1473
    • Shakunaga, T.1    Ozaki, T.2    Ohara, N.3    Asaumi, K.4    Doi, T.5    Nishida, K.6
  • 15
    • 35148849800 scopus 로고    scopus 로고
    • Expression of connective tissue growth factor is in agreement with the expression of VEGF, VEGF-C,-D and associated with shorter survival in gastric cancer
    • Liu L, Li Z, Feng G, You W, Li J. Expression of connective tissue growth factor is in agreement with the expression of VEGF, VEGF-C,-D and associated with shorter survival in gastric cancer. Pathol Int 2007; 57: 712-718.
    • (2007) Pathol Int , vol.57 , pp. 712-718
    • Liu, L.1    Li, Z.2    Feng, G.3    You, W.4    Li, J.5
  • 16
    • 33947591792 scopus 로고    scopus 로고
    • Connective tissue growth factor (CTGF) expression and outcome in adult patients with acute lymphoblastic leukemia
    • Sala-Torra O, Gundacker HM, Stirewalt DL, Ladne PA, Pogosova-Agadjanyan EL, Slovak ML, et al. Connective tissue growth factor (CTGF) expression and outcome in adult patients with acute lymphoblastic leukemia. Blood 2007; 109: 3080-3083.
    • (2007) Blood , vol.109 , pp. 3080-3083
    • Sala-Torra, O.1    Gundacker, H.M.2    Stirewalt, D.L.3    Ladne, P.A.4    Pogosova-Agadjanyan, E.L.5    Slovak, M.L.6
  • 17
    • 33646448419 scopus 로고    scopus 로고
    • Genome-wide gene expression profiling of cervical cancer in Hong Kong women by oligonucleotide microarray
    • Wong YF, Cheung TH, Tsao GS, Lo KW, Yim SF, Wang VW, et al. Genome-wide gene expression profiling of cervical cancer in Hong Kong women by oligonucleotide microarray. Int J Cancer 2006; 118: 2461-2469.
    • (2006) Int J Cancer , vol.118 , pp. 2461-2469
    • Wong, Y.F.1    Cheung, T.H.2    Tsao, G.S.3    Lo, K.W.4    Yim, S.F.5    Wang, V.W.6
  • 18
    • 37549035044 scopus 로고    scopus 로고
    • Connective tissue growth factor is overexpressed in esophageal squamous cell carcinoma and promotes tumorigenicity through beta-catenin-T-cell factor/Lef signaling
    • Deng YZ, Chen PP, Wang Y, Yin D, Koeffler HP, Li B, et al. Connective tissue growth factor is overexpressed in esophageal squamous cell carcinoma and promotes tumorigenicity through beta-catenin-T-cell factor/Lef signaling. J Biol Chem 2007; 282: 36571-36581.
    • (2007) J Biol Chem , vol.282 , pp. 36571-36581
    • Deng, Y.Z.1    Chen, P.P.2    Wang, Y.3    Yin, D.4    Koeffler, H.P.5    Li, B.6
  • 19
    • 33645236966 scopus 로고    scopus 로고
    • Expression profiling of Wilms tumors reveals new candidate genes for different clinical parameters
    • Zirn B, Hartmann O, Samans B, Krause M, Wittmann S, Mertens F, et al. Expression profiling of Wilms tumors reveals new candidate genes for different clinical parameters. Int J Cancer 2006; 118: 1954-1962.
    • (2006) Int J Cancer , vol.118 , pp. 1954-1962
    • Zirn, B.1    Hartmann, O.2    Samans, B.3    Krause, M.4    Wittmann, S.5    Mertens, F.6
  • 20
    • 60049086576 scopus 로고    scopus 로고
    • Expression of Cyr61, CTGF, and WISP-1 correlates with clinical features of lung cancer
    • Chen PP, Li WJ, Wang Y, Zhao S, Li DY, Feng LY, et al. Expression of Cyr61, CTGF, and WISP-1 correlates with clinical features of lung cancer. PLoS One 2007; 2: e534.
    • (2007) PLoS One , vol.2
    • Chen, P.P.1    Li, W.J.2    Wang, Y.3    Zhao, S.4    Li, D.Y.5    Feng, L.Y.6
  • 21
    • 33745247375 scopus 로고    scopus 로고
    • Connective tissue growth factor-specific monoclonal antibody therapy inhibits pancreatic tumor growth and metastasis
    • Dornhöfer N, Spong S, Bennewith K, Salim A, Klaus S, Kambham N, et al. Connective tissue growth factor-specific monoclonal antibody therapy inhibits pancreatic tumor growth and metastasis. Cancer Res 2006; 66: 5816-5827.
    • (2006) Cancer Res , vol.66 , pp. 5816-5827
    • Dornhöfer, N.1    Spong, S.2    Bennewith, K.3    Salim, A.4    Klaus, S.5    Kambham, N.6
  • 22
    • 48949084865 scopus 로고    scopus 로고
    • Connective tissue growth factor: A fibrogenic master switch in fibrotic liver diseases
    • Gressner OA, Gressner AM. Connective tissue growth factor: a fibrogenic master switch in fibrotic liver diseases. Liver Int 2008; 28: 1065-1079.
    • (2008) Liver Int , vol.28 , pp. 1065-1079
    • Gressner, O.A.1    Gressner, A.M.2
  • 23
    • 68949198361 scopus 로고    scopus 로고
    • Validation of connective tissue growth factor (CTGF/CCN2) and its gene polymorphisms as noninvasive biomarkers for the assessment of liver fibrosis
    • Kovalenko E, Tacke F, Gressner OA, Zimmermann HW, Lahme B, Janetzko A, et al. Validation of connective tissue growth factor (CTGF/CCN2) and its gene polymorphisms as noninvasive biomarkers for the assessment of liver fibrosis. J Viral Hepat 2009; 16: 612-620.
    • (2009) J Viral Hepat , vol.16 , pp. 612-620
    • Kovalenko, E.1    Tacke, F.2    Gressner, O.A.3    Zimmermann, H.W.4    Lahme, B.5    Janetzko, A.6
  • 24
    • 0036788304 scopus 로고    scopus 로고
    • Gene silencing in mammals by small interfering RNAs
    • McManus MT, Sharp PA. Gene silencing in mammals by small interfering RNAs. Nat Rev Genet 2002; 3: 737-747.
    • (2002) Nat Rev Genet , vol.3 , pp. 737-747
    • McManus, M.T.1    Sharp, P.A.2
  • 25
    • 78651249549 scopus 로고    scopus 로고
    • Silencing invariant chains of dendritic cells enhances anti-tumor immunity using small-interfering RNA
    • Ke S, Chen XH, Zhu ZG, Li JF, Yu BQ, Gu QL, et al. Silencing invariant chains of dendritic cells enhances anti-tumor immunity using small-interfering RNA. Chin Med J 2010; 123: 3193-3199.
    • (2010) Chin Med J , vol.123 , pp. 3193-3199
    • Ke, S.1    Chen, X.H.2    Zhu, Z.G.3    Li, J.F.4    Yu, B.Q.5    Gu, Q.L.6
  • 26
    • 1642400103 scopus 로고    scopus 로고
    • RNA interference: A practical approach
    • Duxbury MS, Whang EE. RNA interference: a practical approach. J Surg Res 2004; 117: 339-344.
    • (2004) J Surg Res , vol.117 , pp. 339-344
    • Duxbury, M.S.1    Whang, E.E.2
  • 27
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 2001; 411: 494-498.
    • (2001) Nature , vol.411 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3    Yalcin, A.4    Weber, K.5    Tuschl, T.6
  • 28
  • 29
  • 30
    • 33847793202 scopus 로고    scopus 로고
    • Gene silencing by small regulatory RNAs in mammalian cells
    • Scherr M, Eder M. Gene silencing by small regulatory RNAs in mammalian cells. Cell Cycle 2007; 6: 444-449.
    • (2007) Cell Cycle , vol.6 , pp. 444-449
    • Scherr, M.1    Eder, M.2
  • 31
    • 4644318481 scopus 로고    scopus 로고
    • Lentiviral vectors: Optimization of packaging, transduction and gene expression
    • Delenda C. Lentiviral vectors: optimization of packaging, transduction and gene expression. J Gene Med 2004; 6 Suppl 1: S125-S138.
    • (2004) J Gene Med , Issue.6 SUPPL. 1
    • Delenda, C.1
  • 32
    • 34547683376 scopus 로고    scopus 로고
    • The geldanamycin analogue 17-allylamino-17-demethoxygeldanamycin inhibits the growth of GL261 glioma cells in vitro and in vivo
    • Newcomb EW, Lukyanov Y, Schnee T, Esencay M, Fischer I, Hong D, et al. The geldanamycin analogue 17-allylamino-17-demethoxygeldanamycin inhibits the growth of GL261 glioma cells in vitro and in vivo. Anticancer Drugs 2007; 18: 875-882.
    • (2007) Anticancer Drugs , vol.18 , pp. 875-882
    • Newcomb, E.W.1    Lukyanov, Y.2    Schnee, T.3    Esencay, M.4    Fischer, I.5    Hong, D.6
  • 33
    • 0037062951 scopus 로고    scopus 로고
    • RNA interference
    • Hannon GJ. RNA interference. Nature 2002; 418: 244-251.
    • (2002) Nature , vol.418 , pp. 244-251
    • Hannon, G.J.1
  • 34
    • 0005227608 scopus 로고    scopus 로고
    • Small interfering RNAs: A revolutionary tool for the analysis of gene function and gene therapy
    • Tuschl T, Borkhardt A. Small interfering RNAs: a revolutionary tool for the analysis of gene function and gene therapy. Mol Interv 2002; 2: 158-167.
    • (2002) Mol Interv , vol.2 , pp. 158-167
    • Tuschl, T.1    Borkhardt, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.