Dexamethasone and Aβ 25-35 accelerate learning and memory impairments due to elevate amyloid precursor protein expression and neuronal apoptosis in 12-month male rats

Behavioural Brain Research

Volumn 227, Issue 1, 2012, Pages 142-149

  Li, Wei Zu ^a   Li, Wei Ping ^a   Huang, Da Ke ^a   Kan, Hong Wei ^b   Wang, Xin ^a   Wu, Wang Yang ^a   Yin, Yan Yan ^a   Yao, Yu You ^a  

^a ANHUI MEDICAL UNIVERSITY   (China)

^b Anhui Institute of Materia Medica   (China)

Author keywords

AD; Apoptosis; APP; Dexamethasone; Memory and learning impairment

Indexed keywords

4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[25-35]; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; CASPASE 3; CYTOCHROME C; DEXAMETHASONE; MESSENGER RNA; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN (25 35); AMYLOID BETA-PROTEIN (25-35); ARABIDOPSIS PROTEIN; GLUCOCORTICOID; MARNERAL SYNTHASE, ARABIDOPSIS; MUTASE; PEPTIDE FRAGMENT; SECRETASE;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN NERVE CELL; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HIPPOCAMPUS; HISTOPATHOLOGY; LEARNING DISORDER; MALE; MEMORY DISORDER; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROCESSING; RAT; ULTRASTRUCTURE; ANALYSIS OF VARIANCE; ANIMAL; CHEMICALLY INDUCED DISORDER; DISEASE MODEL; DRUG EFFECT; DRUG POTENTIATION; GENE EXPRESSION REGULATION; GENETICS; MAZE TEST; METABOLISM; NERVE CELL; SCANNING ELECTRON MICROSCOPY; SPRAGUE DAWLEY RAT; TIME;

AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANALYSIS OF VARIANCE; ANIMALS; APOPTOSIS; ARABIDOPSIS PROTEINS; CASPASE 3; CYTOCHROMES C; DEXAMETHASONE; DISEASE MODELS, ANIMAL; DRUG SYNERGISM; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; GLUCOCORTICOIDS; HIPPOCAMPUS; INTRAMOLECULAR TRANSFERASES; LEARNING DISORDERS; MALE; MAZE LEARNING; MEMORY DISORDERS; MICROSCOPY, ELECTRON, SCANNING; NEURONS; PEPTIDE FRAGMENTS; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS;

EID: 82155176158     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2011.10.038     Document Type: Article

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