Liquiritigenin inhibits Aβ25-35-induced neurotoxicity and secretion of Aβ1-40 in rat hippocampal neurons

Acta Pharmacologica Sinica

Volumn 30, Issue 7, 2009, Pages 899-906

  Liu, Rui Ting ^a,b   Zou, Li Bo ^b   Lü, Qiu Jun ^a,c  

^a BEIJING INSTITUTE OF RADIATION MEDICINE   (China)

^b SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^c Genova Beijing Biopharmaceutical Research Institute   (China)

Author keywords

A secretion; Liquiritigenin; Neuroprotection; Selective ER agonist

Indexed keywords

AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[25-35]; AMYLOID PRECURSOR PROTEIN; CALCIUM ION; LACTATE DEHYDROGENASE; LIQUIRITIGENIN; NEUROTROPHIN 3; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN (25 35); AMYLOID BETA-PROTEIN (25-35); CALCIUM; FLAVANONE DERIVATIVE; NEUROPROTECTIVE AGENT; PEPTIDE FRAGMENT;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; GENE EXPRESSION PROFILING; HIPPOCAMPUS; NERVE DEGENERATION; NEUROPROTECTION; NEUROTOXICITY; NEUROTROPISM; NONHUMAN; PROTEIN BINDING; PROTEIN SECRETION; RAT; ANIMAL; CELL CULTURE; CELL MEMBRANE PERMEABILITY; CHEMICAL STRUCTURE; CHEMISTRY; CYTOLOGY; DNA MICROARRAY; GENE EXPRESSION; METABOLISM; NERVE CELL; SECRETION; WISTAR RAT;

AMYLOID BETA-PEPTIDES; ANIMALS; CALCIUM; CELL MEMBRANE PERMEABILITY; CELLS, CULTURED; FLAVANONES; GENE EXPRESSION; GENE EXPRESSION PROFILING; HIPPOCAMPUS; MOLECULAR STRUCTURE; NEURONS; NEUROPROTECTIVE AGENTS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PEPTIDE FRAGMENTS; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES;

EID: 67651152791     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2009.74     Document Type: Article

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