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Volumn 7, Issue , 2011, Pages

Lyapunov exponents and phase diagrams reveal multi-factorial control over TRAIL-induced apoptosis

Author keywords

apoptosis; caspases; dynamical systems analysis; kinetic modeling; XIAP

Indexed keywords

CASPASE 3; TNFSF10 PROTEIN, HUMAN; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; X LINKED INHIBITOR OF APOPTOSIS; XIAP PROTEIN, HUMAN;

EID: 82155170633     PISSN: None     EISSN: 17444292     Source Type: Journal    
DOI: 10.1038/msb.2011.85     Document Type: Article
Times cited : (52)

References (55)
  • 1
    • 41549132691 scopus 로고    scopus 로고
    • Quantitative Analysis of Pathways Controlling Extrinsic Apoptosis in Single Cells
    • DOI 10.1016/j.molcel.2008.02.012, PII S1097276508001317
    • Albeck JG, Burke JM, Aldridge BB, Zhang M, LauffenburgerDA, Sorger PK (2008a) Quantitative analysis of pathways controlling extrinsic apoptosis in single cells. Mol Cell 30: 11-25 (Pubitemid 351470145)
    • (2008) Molecular Cell , vol.30 , Issue.1 , pp. 11-25
    • Albeck, J.G.1    Burke, J.M.2    Aldridge, B.B.3    Zhang, M.4    Lauffenburger, D.A.5    Sorger, P.K.6
  • 3
    • 33750533388 scopus 로고    scopus 로고
    • Physicochemical modelling of cell signalling pathways
    • DOI 10.1038/ncb1497, PII NCB1497
    • Aldridge BB, Burke JM, Lauffenburger DA, Sorger PK (2006a) Physicochemical modelling of cell signalling pathways. Nat Cell Biol 8: 1195-1203 (Pubitemid 44660581)
    • (2006) Nature Cell Biology , vol.8 , Issue.11 , pp. 1195-1203
    • Aldridge, B.B.1    Burke, J.M.2    Lauffenburger, D.A.3    Sorger, P.K.4
  • 4
    • 33750809764 scopus 로고    scopus 로고
    • Direct lyapunov exponent analysis enables parametric study of transient signalling governing cell behaviour
    • DOI 10.1049/ip-syb:20050065
    • Aldridge BB, Haller G, Sorger PK, Lauffenburger DA (2006b) Direct Lyapunov exponent analysis enables parametric study of transient signalling governing cell behaviour. Syst Biol (Stevenage) 153: 425-432 (Pubitemid 44712258)
    • (2006) IEE Proceedings: Systems Biology , vol.153 , Issue.6 , pp. 425-432
    • Aldridge, B.B.1    Haller, G.2    Sorger, P.K.3    Lauffenburger, D.A.4
  • 7
    • 0036718393 scopus 로고    scopus 로고
    • XIAP inhibition of caspase-3 preserves its association with the Apaf-1 apoptosome and prevents CD95- and Bax-induced apoptosis
    • DOI 10.1038/sj.cdd.4401069
    • Bratton SB, Lewis J, Butterworth M, Duckett CS, Cohen GM (2002) XIAP inhibition of caspase-3 preserves its association with the Apaf-1 apoptosome and prevents CD95- and Bax-induced apoptosis. Cell Death Differ 9: 881-892 (Pubitemid 35023604)
    • (2002) Cell Death and Differentiation , vol.9 , Issue.9 , pp. 881-892
    • Bratton, S.B.1    Lewis, J.2    Butterworth, M.3    Duckett, C.S.4    Cohen, G.M.5
  • 8
    • 0017105452 scopus 로고
    • Some paradoxical effects of inhibitors of protein synthesis on protein turnover in cultured human cells
    • Ceccarini C, Eagle H (1976) Some paradoxical effects of inhibitors of protein synthesis on protein turnover in cultured human cells. In Vitro 12: 346-351
    • (1976) Vitro , vol.12 , pp. 346-351
    • Ceccarini, C.1    Eagle, H.2
  • 9
    • 34548791699 scopus 로고    scopus 로고
    • Optimal pollution mitigation in monterey bay based on coastal radar data and nonlinear dynamics
    • DOI 10.1021/es0630691
    • Coulliette C, Lekien F, Paduan JD, Haller G, Marsden JE (2007) Optimal pollution mitigation in monterey bay based on coastal radar data and nonlinear dynamics. Environ Sci Technol 41: 6562-6572 (Pubitemid 47438001)
    • (2007) Environmental Science and Technology , vol.41 , Issue.18 , pp. 6562-6572
    • Coulliette, C.1    Lekien, F.2    Paduan, J.D.3    Haller, G.4    Marsden, J.E.5
  • 10
    • 2342615480 scopus 로고    scopus 로고
    • X-Linked Inhibitor of Apoptosis Protein (XIAP) Is a Nonredundant Modulator of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL)-Mediated Apoptosis in Human Cancer Cells
    • DOI 10.1158/0008-5472.CAN-04-0046
    • Cummins JM, Kohli M, Rago C, Kinzler KW, Vogelstein B, Bunz F (2004) X-linked inhibitor of apoptosis protein (XIAP) is a nonredundant modulator of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis in human cancer cells. Cancer Res 64: 3006-3008 (Pubitemid 38581397)
    • (2004) Cancer Research , vol.64 , Issue.9 , pp. 3006-3008
    • Cummins, J.M.1    Kohli, M.2    Rago, C.3    Kinzler, K.W.4    Vogelstein, B.5    Bunz, F.6
  • 11
    • 0030810926 scopus 로고    scopus 로고
    • X-linked IAP is a direct inhibitor of cell-death proteases
    • DOI 10.1038/40901
    • Deveraux QL, Takahashi R, Salvesen GS, Reed JC (1997) X-linked IAP is a direct inhibitor of cell-death proteases. Nature 388: 300-304 (Pubitemid 27317977)
    • (1997) Nature , vol.388 , Issue.6639 , pp. 300-304
    • Deveraux, Q.L.1    Takahashi, R.2    Salvesen, G.S.3    Reed, J.C.4
  • 12
    • 33749252583 scopus 로고    scopus 로고
    • Human inhibitor of apoptosis proteins: Why XIAP is the black sheep of the family
    • DOI 10.1038/sj.embor.7400795, PII 7400795
    • Eckelman BP, Salvesen GS, Scott FL (2006) Human inhibitor of apoptosis proteins: why XIAP is the black sheep of the family. EMBO Rep 7: 988-994 (Pubitemid 44480512)
    • (2006) EMBO Reports , vol.7 , Issue.10 , pp. 988-994
    • Eckelman, B.P.1    Salvesen, G.S.2    Scott, F.L.3
  • 14
    • 84971185409 scopus 로고
    • The Correlation between relatives under the supposition of Mendelian inheritance
    • Fisher RA (1918) The Correlation between relatives under the supposition of Mendelian inheritance. Trans R Soc Endinburgh 52: 399-433
    • (1918) Trans R Soc Endinburgh , vol.52 , pp. 399-433
    • Fisher, R.A.1
  • 17
    • 0028064701 scopus 로고
    • Segregation of APO-1/Fas antigen- and tumor necrosis factor receptor-mediated apoptosis
    • DOI 10.1002/eji.1830241045
    • Grell M, Krammer PH, Scheurich P (1994) Segregation of APO-1/Fas antigen- and tumor necrosis factor receptor-mediated apoptosis. Eur J Immunol 24: 2563-2566 (Pubitemid 24303108)
    • (1994) European Journal of Immunology , vol.24 , Issue.10 , pp. 2563-2566
    • Grell, M.1    Krammer, P.H.2    Scheurich, P.3
  • 21
    • 34250346095 scopus 로고    scopus 로고
    • Analysis of CD95 threshold signaling: Triggering of CD95 (FAS/APO-1) at low concentrations primarily results in survival signaling
    • DOI 10.1074/jbc.M700434200
    • Lavrik IN, Golks A, Riess D, Bentele M, Eils R, Krammer PH (2007) Analysis of CD95 threshold signaling: triggering of CD95 (FAS/ APO-1) at low concentrations primarily results in survival signaling. J Biol Chem 282: 13664-13671 (Pubitemid 47100557)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.18 , pp. 13664-13671
    • Lavrik, I.N.1    Golks, A.2    Riess, D.3    Bentele, M.4    Eils, R.5    Krammer, P.H.6
  • 24
    • 77956528790 scopus 로고    scopus 로고
    • Fundamental limits on the suppression of molecular fluctuations
    • Lestas I, Vinnicombe G, Paulsson J (2010) Fundamental limits on the suppression of molecular fluctuations. Nature 467: 174-178
    • (2010) Nature , vol.467 , pp. 174-178
    • Lestas, I.1    Vinnicombe, G.2    Paulsson, J.3
  • 25
    • 38549145044 scopus 로고    scopus 로고
    • Diagnosing and exploiting cancer's addiction to blocks in apoptosis
    • DOI 10.1038/nrc2297, PII NRC2297
    • Letai AG (2008) Diagnosing and exploiting cancers addiction to blocks in apoptosis. Nat Rev Cancer 8: 121-132 (Pubitemid 351161322)
    • (2008) Nature Reviews Cancer , vol.8 , Issue.2 , pp. 121-132
    • Letai, A.G.1
  • 26
    • 77956630795 scopus 로고    scopus 로고
    • TRAIL treatment provokes mutations in surviving cells
    • Lovric MM, Hawkins CJ (2010) TRAIL treatment provokes mutations in surviving cells. Oncogene 29: 5048-5060
    • (2010) Oncogene , vol.29 , pp. 5048-5060
    • Lovric, M.M.1    Hawkins, C.J.2
  • 27
    • 77956702972 scopus 로고    scopus 로고
    • Smac/DIABLO release from mitochondria and XIAP inhibition are essential to limit clonogenicity of Type i tumor cells after TRAIL receptor stimulation
    • Maas C, Verbrugge I, de Vries E, Savich G, van de Kooij LW, Tait SW, Borst J (2010) Smac/DIABLO release from mitochondria and XIAP inhibition are essential to limit clonogenicity of Type I tumor cells after TRAIL receptor stimulation. Cell Death Differ 17: 1613-1623
    • (2010) Cell Death Differ , vol.17 , pp. 1613-1623
    • Maas, C.1    Verbrugge, I.2    De Vries, E.3    Savich, G.4    Van De Kooij, L.W.5    Tait, S.W.6    Borst, J.7
  • 28
    • 0037184113 scopus 로고    scopus 로고
    • Proteasomemediated degradation of Smac during apoptosis: XIAP promotes Smac ubiquitination in vitro
    • MacFarlane M, MerrisonW, Bratton SB, CohenGM(2002) Proteasomemediated degradation of Smac during apoptosis: XIAP promotes Smac ubiquitination in vitro. J Biol Chem 277: 36611-36616
    • (2002) J Biol Chem , vol.277 , pp. 36611-36616
    • MacFarlane, M.1    Merrisonw Bratton, S.B.2    Cohengm3
  • 29
    • 62449166171 scopus 로고    scopus 로고
    • TRAIL the holy grail of cancer therapy?
    • Newsom-Davis T, Prieske S, Walczak H (2009) Is TRAIL the holy grail of cancer therapy? Apoptosis 14: 607-623
    • (2009) Apoptosis , vol.14 , pp. 607-623
    • Newsom-Davis, T.1    Prieske, S.2    Walczak, H.3
  • 30
    • 77952784381 scopus 로고    scopus 로고
    • Inducible dimerization and inducible cleavage reveal a requirement for both processes in caspase-8 activation
    • Oberst A, Pop C, Tremblay AG, Blais V, Denault JB, Salvesen GS, Green DR (2010) Inducible dimerization and inducible cleavage reveal a requirement for both processes in caspase-8 activation. J Biol Chem 285: 16632-16642
    • (2010) J Biol Chem , vol.285 , pp. 16632-16642
    • Oberst, A.1    Pop, C.2    Tremblay, A.G.3    Blais, V.4    Denault, J.B.5    Salvesen, G.S.6    Green, D.R.7
  • 31
    • 0036859738 scopus 로고    scopus 로고
    • Defining characteristics of types I and II apoptotic cells in response to TRAIL
    • DOI 10.1038/sj.neo.7900270
    • Ozoren N, El-Deiry WS (2002) Defining characteristics of types I and II apoptotic cells in response to TRAIL. Neoplasia 4: 551-557 (Pubitemid 35417080)
    • (2002) Neoplasia , vol.4 , Issue.6 , pp. 551-557
    • Ozoren, N.1    El-Deiry, W.S.2
  • 32
    • 77951652692 scopus 로고    scopus 로고
    • Thresholds in transient dynamics of signal transduction pathways
    • Rateitschak K, Wolkenhauer O (2010) Thresholds in transient dynamics of signal transduction pathways. J Theor Biol 264: 334-346
    • (2010) J Theor Biol , vol.264 , pp. 334-346
    • Rateitschak, K.1    Wolkenhauer, O.2
  • 33
    • 33748941571 scopus 로고    scopus 로고
    • Systems analysis of effector caspase activation and its control by X-linked inhibitor of apoptosis protein
    • DOI 10.1038/sj.emboj.7601295, PII 7601295
    • Rehm M, Huber HJ, Dussmann H, Prehn JH (2006) Systems analysis of effector caspase activation and its control by X-linked inhibitor of apoptosis protein. EMBO J 25: 4338-4349 (Pubitemid 44435231)
    • (2006) EMBO Journal , vol.25 , Issue.18 , pp. 4338-4349
    • Rehm, M.1    Huber, H.J.2    Dussmann, H.3    Prehn, J.H.M.4
  • 35
    • 2942581328 scopus 로고    scopus 로고
    • Disruption of mitochondrial function during apoptosis is mediated by caspase cleavage of the p75 subunit of complex I of the electron transport chain
    • DOI 10.1016/j.cell.2004.05.008, PII S0092867404004969
    • Ricci JE, Munoz-Pinedo C, Fitzgerald P, Bailly-Maitre B, Perkins GA, Yadava N, Scheffler IE, Ellisman MH, Green DR (2004) Disruption of mitochondrial function during apoptosis is mediated by caspase cleavage of the p75 subunit of complex I of the electron transport chain. Cell 117: 773-786 (Pubitemid 38748893)
    • (2004) Cell , vol.117 , Issue.6 , pp. 773-786
    • Ricci, J.-E.1    Munoz-Pinedo, C.2    Fitzgerald, P.3    Bailly-Maitre, B.4    Perkins, G.A.5    Yadava, N.6    Scheffler, I.E.7    Ellisman, M.H.8    Green, D.R.9
  • 36
    • 8444220527 scopus 로고    scopus 로고
    • Molecular mechanisms of caspase regulation during apoptosis
    • DOI 10.1038/nrm1496
    • Riedl SJ, Shi Y (2004) Molecular mechanisms of caspase regulation during apoptosis. Nat Rev Mol Cell Biol 5: 897-907 (Pubitemid 39486541)
    • (2004) Nature Reviews Molecular Cell Biology , vol.5 , Issue.11 , pp. 897-907
    • Riedl, S.J.1    Shi, Y.2
  • 37
    • 12444288591 scopus 로고    scopus 로고
    • Type I and type II reactions in TRAIL-induced apoptosis - Results from dose-response studies
    • DOI 10.1038/sj.onc.1208191
    • Rudner J, Jendrossek V, Lauber K, Daniel PT, Wesselborg S, Belka C (2005) Type I and type II reactions in TRAIL-induced apoptosis- results from dose-response studies. Oncogene 24: 130-140 (Pubitemid 40143872)
    • (2005) Oncogene , vol.24 , Issue.1 , pp. 130-140
    • Rudner, J.1    Jendrossek, V.2    Lauber, K.3    Daniel, P.T.4    Wesselborg, S.5    Belka, C.6
  • 39
    • 0033556310 scopus 로고    scopus 로고
    • The role of c-FLIP in modulation of CD95-induced apoptosis
    • Scaffidi C, Schmitz I, Krammer PH, Peter ME (1999a) The role of c-FLIP in modulation of CD95-induced apoptosis. J Biol Chem 274: 1541-1548
    • (1999) J Biol Chem , vol.274 , pp. 1541-1548
    • Scaffidi, C.1    Schmitz, I.2    Krammer, P.H.3    Peter, M.E.4
  • 40
  • 41
    • 50049110244 scopus 로고    scopus 로고
    • Regulation of apoptosis by XIAP ubiquitin-ligase activity
    • Schile AJ, Garcia-Fernandez M, Steller H (2008) Regulation of apoptosis by XIAP ubiquitin-ligase activity. Genes Dev 22: 2256-2266
    • (2008) Genes Dev , vol.22 , pp. 2256-2266
    • Schile, A.J.1    Garcia-Fernandez, M.2    Steller, H.3
  • 42
    • 0032832881 scopus 로고    scopus 로고
    • Differences between CD95 type I and type II cells detected with the CD95 ligand [1]
    • Schmitz I, Walczak H, Krammer PH, Peter ME (1999) Differences between CD95 type I and II cells detected with the CD95 ligand. Cell Death Differ 6: 821-822 (Pubitemid 29488078)
    • (1999) Cell Death and Differentiation , vol.6 , Issue.9 , pp. 821-822
    • Schmitz, I.1    Walczak, H.2    Krammer, P.H.3    Peter, M.E.4
  • 43
    • 70450248386 scopus 로고    scopus 로고
    • Caspase-9 activation by the apoptosome is not required for fas-mediated apoptosis in type II Jurkat cells
    • Shawgo ME, Shelton SN, Robertson JD (2009) Caspase-9 activation by the apoptosome is not required for fas-mediated apoptosis in type II Jurkat cells. J Biol Chem 284: 33447-33455
    • (2009) J Biol Chem , vol.284 , pp. 33447-33455
    • Shawgo, M.E.1    Shelton, S.N.2    Robertson, J.D.3
  • 44
    • 9444268061 scopus 로고    scopus 로고
    • SPOTS: Signaling protein oligomeric transduction structures are early mediators of death receptor-induced apoptosis at the plasma membrane
    • DOI 10.1083/jcb.200406101
    • Siegel RM, Muppidi JR, Sarker M, Lobito A, Jen M, Martin D, Straus SE, Lenardo MJ (2004) SPOTS: signaling protein oligomeric transduction structures are early mediators of death receptorinduced apoptosis at the plasma membrane. J Cell Biol 167: 735-744 (Pubitemid 39565153)
    • (2004) Journal of Cell Biology , vol.167 , Issue.4 , pp. 735-744
    • Siegel, R.M.1    Muppidi, J.R.2    Sarker, M.3    Lobito, A.4    Jen, M.5    Martin, D.6    Straus, S.E.7    Lenardo, M.J.8
  • 46
    • 66249136447 scopus 로고    scopus 로고
    • Nongenetic origins of cell-to-cell variability in TRAIL-induced apoptosis
    • Spencer SL, Gaudet S, Albeck JG, Burke JM, Sorger PK (2009) Nongenetic origins of cell-to-cell variability in TRAIL-induced apoptosis. Nature 459: 428-433
    • (2009) Nature , vol.459 , pp. 428-433
    • Spencer, S.L.1    Gaudet, S.2    Albeck, J.G.3    Burke, J.M.4    Sorger, P.K.5
  • 47
    • 0037192790 scopus 로고    scopus 로고
    • L inhibit CD95-mediated apoptosis by preventing mitochondrial release of Smac/DIABLO and subsequent inactivation of X-linked inhibitor-of-apoptosis protein
    • DOI 10.1074/jbc.M109893200
    • Sun XM, Bratton SB, Butterworth M, MacFarlane M, Cohen GM (2002) Bcl-2 and Bcl-xL inhibit CD95-mediated apoptosis by preventing mitochondrial release of Smac/DIABLO and subsequent inactivation of X-linked inhibitor-of-apoptosis protein. J Biol Chem 277: 11345-11351 (Pubitemid 34952900)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.13 , pp. 11345-11351
    • Sun, X.-M.1    Bratton, S.B.2    Butterworth, M.3    MacFarlane, M.4    Cohen, G.M.5
  • 48
    • 0035920126 scopus 로고    scopus 로고
    • Xlinked inhibitor of apoptosis protein (XIAP) inhibits caspase-3 and - 7 in distinct modes
    • Suzuki Y, Nakabayashi Y, Nakata K, Reed JC, Takahashi R (2001) Xlinked inhibitor of apoptosis protein (XIAP) inhibits caspase-3 and - 7 in distinct modes. J Biol Chem 276: 27058-27063
    • (2001) J Biol Chem , vol.276 , pp. 27058-27063
    • Suzuki, Y.1    Nakabayashi, Y.2    Nakata, K.3    Reed, J.C.4    Takahashi, R.5
  • 49
    • 0034280126 scopus 로고    scopus 로고
    • Rapid caspase- 3 activation during apoptosis revealed using fluorescenceresonance energy transfer
    • Tyas L, Brophy VA, Pope A, Rivett AJ, Tavare JM (2000) Rapid caspase- 3 activation during apoptosis revealed using fluorescenceresonance energy transfer. EMBO Rep 1: 266-270
    • (2000) EMBO Rep , vol.1 , pp. 266-270
    • Tyas, L.1    Brophy, V.A.2    Pope, A.3    Rivett, A.J.4    Tavare, J.M.5
  • 50
  • 51
    • 20444399180 scopus 로고    scopus 로고
    • Surviving apoptosis: A possible mechanism of benzene-induced leukemia
    • DOI 10.1016/j.cbi.2005.03.022, PII S0009279705000840, Proceedings of the International Symposium on Recent Advancis in Benzene Toxicity
    • Vaughan AT, Betti CJ, Villalobos MJ, Premkumar K, Cline E, Jiang Q, Diaz MO (2005) Surviving apoptosis: a possible mechanism of benzene-induced leukemia. Chem Biol Interact 153-154: 179-185 (Pubitemid 40797809)
    • (2005) Chemico-Biological Interactions , vol.153-154 , pp. 179-185
    • Vaughan, A.T.1    Betti, C.J.2    Villalobos, M.J.3    Premkumar, K.4    Cline, E.5    Jiang, Q.6    Diaz, M.O.7
  • 53
    • 77958493422 scopus 로고    scopus 로고
    • The caspase-8 dimerization/dissociation balance is a highly potent regulator of caspase-8, -3, -6 signaling
    • Wurstle ML, Laussmann M.A., Rehm M (2010) The caspase-8 dimerization/dissociation balance is a highly potent regulator of caspase-8, -3, -6 signaling. J Biol Chem 285: 33209-33218
    • (2010) J Biol Chem , vol.285 , pp. 33209-33218
    • Wurstle, M.L.1    Laussmann, M.A.2    Rehm, M.3
  • 54
    • 0034607655 scopus 로고    scopus 로고
    • Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli
    • DOI 10.1126/science.288.5467.874
    • Yang Y, Fang S, Jensen JP,Weissman A.M., Ashwell JD (2000) Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli. Science 288: 874-877 (Pubitemid 30257739)
    • (2000) Science , vol.288 , Issue.5467 , pp. 874-877
    • Yang, Y.1    Fang, S.2    Jensen, J.P.3    Weissman, A.M.4    Ashwell, J.D.5
  • 55
    • 0009000367 scopus 로고
    • On the theory of inheritance of quantitative compound characters on the basis of Mendels laws-a preliminary note
    • Yule GU (1906) On the theory of inheritance of quantitative compound characters on the basis of Mendels laws-a preliminary note. In Third International Conference on Genetics, pp 140-142
    • (1906) Third International Conference on Genetics , pp. 140-142
    • Yule, G.U.1


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