-
2
-
-
33750809764
-
Direct Lyapunov exponent analysis enables parametric study of transient signaling governing cell behavior
-
Aldridge B.B., Haller G., Sorger P.K., Lauffenburger D.A. Direct Lyapunov exponent analysis enables parametric study of transient signaling governing cell behavior. IEE Proc. Syst. Biol. 2006, 153:425-432.
-
(2006)
IEE Proc. Syst. Biol.
, vol.153
, pp. 425-432
-
-
Aldridge, B.B.1
Haller, G.2
Sorger, P.K.3
Lauffenburger, D.A.4
-
3
-
-
4544246088
-
Mathematical modeling reveals threshold mechanism in CD95-induced apoptosis
-
Bentele M., Lavrik I., Ulrich M., Stosser S., Heermann D.W., Kalthoff H., Krammer P.H., Eils R. Mathematical modeling reveals threshold mechanism in CD95-induced apoptosis. J. Cell. Biol. 2004, 166:839-851.
-
(2004)
J. Cell. Biol.
, vol.166
, pp. 839-851
-
-
Bentele, M.1
Lavrik, I.2
Ulrich, M.3
Stosser, S.4
Heermann, D.W.5
Kalthoff, H.6
Krammer, P.H.7
Eils, R.8
-
4
-
-
0037047611
-
MAP kinase phosphatase as a locus of flexibility in a mitogen activated protein kinase signaling network
-
Bhalla U.S., Ram T.P., Iyengar R. MAP kinase phosphatase as a locus of flexibility in a mitogen activated protein kinase signaling network. Science 2002, 297:1018-1023.
-
(2002)
Science
, vol.297
, pp. 1018-1023
-
-
Bhalla, U.S.1
Ram, T.P.2
Iyengar, R.3
-
5
-
-
0042424655
-
Transcriptional regulatory cascades in development: initial rates, not steady state, determine network kinetics
-
Bolouri H., Davidson E.H. Transcriptional regulatory cascades in development: initial rates, not steady state, determine network kinetics. Proc. Natl. Acad. Sci. 2003, 100:9371-9376.
-
(2003)
Proc. Natl. Acad. Sci.
, vol.100
, pp. 9371-9376
-
-
Bolouri, H.1
Davidson, E.H.2
-
6
-
-
67149138163
-
Protein sequestation generates a flexible ultrasensitive response in a genetic network
-
Buchler N.E., Cross F.R. Protein sequestation generates a flexible ultrasensitive response in a genetic network. Mol. Syst. Biol. 2009, 5:272.
-
(2009)
Mol. Syst. Biol.
, vol.5
, pp. 272
-
-
Buchler, N.E.1
Cross, F.R.2
-
7
-
-
0036195958
-
Metabolic contol analysis in drug discovery and disease
-
Cascante M., Boros L.G., Comin-Anduix B., de Atauri P., Centelles J.J., Lee P.W.N. Metabolic contol analysis in drug discovery and disease. Nat. Biotechnol. 2002, 20:243-249.
-
(2002)
Nat. Biotechnol.
, vol.20
, pp. 243-249
-
-
Cascante, M.1
Boros, L.G.2
Comin-Anduix, B.3
de Atauri, P.4
Centelles, J.J.5
Lee, P.W.N.6
-
8
-
-
33646382406
-
Transient IKK activity mediates NF-κ temporal dynamics in response to a wide range of TNFα doses'
-
Cheong R., Bergmann A., Werner S.L., Regal J., Hoffmann A., Levchenko A. Transient IKK activity mediates NF-κB temporal dynamics in response to a wide range of TNFα doses'. J. Biol. Chem. 2005, 281:2945-2950.
-
(2005)
J. Biol. Chem.
, vol.281
, pp. 2945-2950
-
-
Cheong, R.1
Bergmann, A.2
Werner, S.L.3
Regal, J.4
Hoffmann, A.5
Levchenko, A.6
-
9
-
-
71149092283
-
Dynamics and Variability of ERK2 Response to EGF in individual living cells
-
Cohen-Saidon A., Cohen A.A., Sigal A., Liron Y., Alon U. Dynamics and Variability of ERK2 Response to EGF in individual living cells. Mol. Cell 2009, 36:885-893.
-
(2009)
Mol. Cell
, vol.36
, pp. 885-893
-
-
Cohen-Saidon, A.1
Cohen, A.A.2
Sigal, A.3
Liron, Y.4
Alon, U.5
-
10
-
-
0035799284
-
Cooperativity in transcriptional control
-
Courey A. Cooperativity in transcriptional control. Curr. Biol. 2001, 11:250-252.
-
(2001)
Curr. Biol.
, vol.11
, pp. 250-252
-
-
Courey, A.1
-
11
-
-
35949018382
-
Ergodic theory of chaos and strange attractors
-
Eckmann J.P., Ruelle D. Ergodic theory of chaos and strange attractors. Rev. Mod. Phys. 1985, 57:617-656.
-
(1985)
Rev. Mod. Phys.
, vol.57
, pp. 617-656
-
-
Eckmann, J.P.1
Ruelle, D.2
-
12
-
-
85058206480
-
Tripping the switch fantastic: how a protein kinase cascade can convert graded input into switch-like outputs
-
Ferrell J.E. Tripping the switch fantastic: how a protein kinase cascade can convert graded input into switch-like outputs. TIBS 1996, 21:466-640.
-
(1996)
TIBS
, vol.21
, pp. 466-640
-
-
Ferrell, J.E.1
-
13
-
-
0032496358
-
The biochemical basis of an all-or-none cell fate switch in Xenopus oocytes
-
Ferrell J.E., Machleder E.M. The biochemical basis of an all-or-none cell fate switch in Xenopus oocytes. Science 1998, 280:895-898.
-
(1998)
Science
, vol.280
, pp. 895-898
-
-
Ferrell, J.E.1
Machleder, E.M.2
-
14
-
-
0001424903
-
An amplified sensitivity arising from covalent modification in biological systems
-
Goldbeter A., Koshland D.E. An amplified sensitivity arising from covalent modification in biological systems. Proc. Natl. Acad. Sci. USA 1981, 78:6840-6844.
-
(1981)
Proc. Natl. Acad. Sci. USA
, vol.78
, pp. 6840-6844
-
-
Goldbeter, A.1
Koshland, D.E.2
-
15
-
-
34250093291
-
Scaling laws for invariant measures on hyperbolic and nonhyperbolic attractors
-
Grassberger P., Badii R., Politi A. Scaling laws for invariant measures on hyperbolic and nonhyperbolic attractors. J. Stat. Phys. 1988, 51:135-178.
-
(1988)
J. Stat. Phys.
, vol.51
, pp. 135-178
-
-
Grassberger, P.1
Badii, R.2
Politi, A.3
-
16
-
-
26844571282
-
Multisite protein phosphorylation makes a good threshold but can be a poor switch
-
Gunarwardena J. Multisite protein phosphorylation makes a good threshold but can be a poor switch. Proc. Natl. Acad. Sci. USA 2005, 102:14617-14622.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 14617-14622
-
-
Gunarwardena, J.1
-
17
-
-
0034823558
-
Distinguished material surfaces and coherent structures in three-dimensional fluid flows
-
Haller G. Distinguished material surfaces and coherent structures in three-dimensional fluid flows. Physica D 2001, 149:248-277.
-
(2001)
Physica D
, vol.149
, pp. 248-277
-
-
Haller, G.1
-
18
-
-
0344012556
-
Regulators of G protein signaling and transient activation of signaling: experimental and computational analysis reveals negative and positive feedback controls on G protein activity
-
Hao N., Yildirim N., Wang Y., Elston T.C., Dohlman H.G. Regulators of G protein signaling and transient activation of signaling: experimental and computational analysis reveals negative and positive feedback controls on G protein activity. J. Biol. Chem. 2003, 278:46506-46515.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 46506-46515
-
-
Hao, N.1
Yildirim, N.2
Wang, Y.3
Elston, T.C.4
Dohlman, H.G.5
-
20
-
-
11444260258
-
Principles behind the multifarious control of signal transduction ERK phosphorylation and kinase/phosphatase control
-
Hornberg J.J., Bruggeman F.J., Binder B., Geest C.R., Vaate A.J.M.B.de., Lankelma J., Heinrich R., Westerhoff H.V. Principles behind the multifarious control of signal transduction ERK phosphorylation and kinase/phosphatase control. FEBS J. 2005, 272:244-258.
-
(2005)
FEBS J.
, vol.272
, pp. 244-258
-
-
Hornberg, J.J.1
Bruggeman, F.J.2
Binder, B.3
Geest, C.R.4
Vaate, A.5
Lankelma, J.6
Heinrich, R.7
Westerhoff, H.V.8
-
21
-
-
0029790351
-
Ultrasensitivity in the mitogen-activated protein kinase cascade
-
Huang C.Y.F., Ferrell J.E. Ultrasensitivity in the mitogen-activated protein kinase cascade. Proc. Natl. Acad. Sci. USA 1996, 93:10078-10083.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 10078-10083
-
-
Huang, C.Y.F.1
Ferrell, J.E.2
-
22
-
-
0037466509
-
Sensitivity analysis of stoichiometric networks: an extension of metabolic control analysis to non-steady state trajectories
-
Ingalls B.P., Sauro H.M. Sensitivity analysis of stoichiometric networks: an extension of metabolic control analysis to non-steady state trajectories. J. Theor. Biol. 2003, 222:23-36.
-
(2003)
J. Theor. Biol.
, vol.222
, pp. 23-36
-
-
Ingalls, B.P.1
Sauro, H.M.2
-
23
-
-
0035947724
-
Identification of the mechanisms regulating the differential activation of the mapk cascade by epidermal growth factor and nerve growth factor in PC12 cells
-
Kao S., Jaiswal R.K., Kolch W., Landreth G.E. Identification of the mechanisms regulating the differential activation of the mapk cascade by epidermal growth factor and nerve growth factor in PC12 cells. J. Biol. Chem. 2001, 276:18169-18177.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 18169-18177
-
-
Kao, S.1
Jaiswal, R.K.2
Kolch, W.3
Landreth, G.E.4
-
24
-
-
23844525556
-
Quantitative analysis of ultrasensitive response
-
Legewie S., Blüthgen N., Herzel H. Quantitative analysis of ultrasensitive response. FEBS J. 2005, 272:4071-4079.
-
(2005)
FEBS J.
, vol.272
, pp. 4071-4079
-
-
Legewie, S.1
Blüthgen, N.2
Herzel, H.3
-
25
-
-
0035282929
-
What do mitochondrial diseases teach us about normal mitochondrial functions. . that we already knew: threshold expression of mitochondrial defects
-
Mazat J.P., Rossignol R., Malgat M., Rocher C., Faustin B., Letellier T. What do mitochondrial diseases teach us about normal mitochondrial functions. . that we already knew: threshold expression of mitochondrial defects. Biochim. Biophys. Acta 2001, 1504:20-30.
-
(2001)
Biochim. Biophys. Acta
, vol.1504
, pp. 20-30
-
-
Mazat, J.P.1
Rossignol, R.2
Malgat, M.3
Rocher, C.4
Faustin, B.5
Letellier, T.6
-
26
-
-
0035969559
-
Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication
-
Nash P., Tang X., Orlicky S., Chen Q., Gertler F.B., Mendenhall M.D., Sicheri F., Pawson T., Tyers M. Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication. Nature 2001, 414:514-521.
-
(2001)
Nature
, vol.414
, pp. 514-521
-
-
Nash, P.1
Tang, X.2
Orlicky, S.3
Chen, Q.4
Gertler, F.B.5
Mendenhall, M.D.6
Sicheri, F.7
Pawson, T.8
Tyers, M.9
-
27
-
-
0003582543
-
-
Cambridge University Press, Cambridge
-
Ott E. Chaos in Dynamical Systems 1994, Cambridge University Press, Cambridge.
-
(1994)
Chaos in Dynamical Systems
-
-
Ott, E.1
-
28
-
-
33846820252
-
Versatile regulation of multisite protein phosphorylation by the order of phosphate processing and protein-protein interactions
-
Salazar C., Höfer T. Versatile regulation of multisite protein phosphorylation by the order of phosphate processing and protein-protein interactions. FEBS J. 2007, 274:1046-1061.
-
(2007)
FEBS J.
, vol.274
, pp. 1046-1061
-
-
Salazar, C.1
Höfer, T.2
-
29
-
-
17344362384
-
Prediction and validation of the distinct dynamics of transient and sustained ERK activation
-
Sasagawa S., Ozaki Y.I., Fujita K., Kuroda S. Prediction and validation of the distinct dynamics of transient and sustained ERK activation. Nat. Cell Biol. 2005, 7:365-373.
-
(2005)
Nat. Cell Biol.
, vol.7
, pp. 365-373
-
-
Sasagawa, S.1
Ozaki, Y.I.2
Fujita, K.3
Kuroda, S.4
-
30
-
-
36749094352
-
Input output robustness in simple bacterial signaling systems
-
Shinar G., Milo R., Martinez M.R., Alon U. Input output robustness in simple bacterial signaling systems. Proc. Natl. Acad. Sci. USA 2007, 104:19931-19935.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 19931-19935
-
-
Shinar, G.1
Milo, R.2
Martinez, M.R.3
Alon, U.4
-
31
-
-
77951652940
-
-
The MathWorks Inc. Matlab 7.5.0 R2007b 〈〉.
-
The MathWorks Inc. Matlab 7.5.0 R2007b 2007. 〈〉. http://www.mathworks.com.
-
(2007)
-
-
-
32
-
-
66249140972
-
SysBioMed report: advancing systems biology for medical application
-
Wolkenhauer O., Fell D., De Meyts P., Bluethgen N., Herzel H., Le Novere N., Hoefer T., Schuerrle K., van Leeuwen I. SysBioMed report: advancing systems biology for medical application. IET Syst. Biol. 2009, 3:131-136.
-
(2009)
IET Syst. Biol.
, vol.3
, pp. 131-136
-
-
Wolkenhauer, O.1
Fell, D.2
De Meyts, P.3
Bluethgen, N.4
Herzel, H.5
Le Novere, N.6
Hoefer, T.7
Schuerrle, K.8
van Leeuwen, I.9
-
33
-
-
33746618464
-
Comparative study of parameter sensitivity analyses of the TCR-activated Erk-MAPK signaling pathway
-
Zhang Y., Rundell A. Comparative study of parameter sensitivity analyses of the TCR-activated Erk-MAPK signaling pathway. IEE Proc. Syst. Biol. Sy. 2006, 153:210-211.
-
(2006)
IEE Proc. Syst. Biol. Sy.
, vol.153
, pp. 210-211
-
-
Zhang, Y.1
Rundell, A.2
|