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Volumn 3, Issue 12, 2011, Pages 969-973

Remodelling of the natural product fumagillol employing a reaction discovery approach

Author keywords

[No Author keywords available]

Indexed keywords

AMINE; CYCLOHEXANE DERIVATIVE; FUMAGILLOL; SESQUITERPENE;

EID: 82055161640     PISSN: 17554330     EISSN: 17554349     Source Type: Journal    
DOI: 10.1038/nchem.1178     Document Type: Article
Times cited : (81)

References (48)
  • 1
    • 71049126548 scopus 로고    scopus 로고
    • Escape from flatland: Increasing saturation as an approach to improving clinical success
    • Lovering, F., Bikker, J. & Humblet, C. Escape from flatland: Increasing saturation as an approach to improving clinical success. J. Med. Chem. 52, 6752-6756 (2009).
    • (2009) J. Med. Chem. , vol.52 , pp. 6752-6756
    • Lovering, F.1    Bikker, J.2    Humblet, C.3
  • 2
    • 84880296641 scopus 로고    scopus 로고
    • Diversity-oriented synthesis as a tool for the discovery of novel biologically active small molecules
    • Galloway, W. R. J. D., Isidro-Llobet, A. & Spring, D. R. Diversity-oriented synthesis as a tool for the discovery of novel biologically active small molecules. Nature Commun. 1, 80 (2010)
    • (2010) Nature Commun. , vol.1 , pp. 80
    • Galloway, W.R.J.D.1    Isidro-Llobet, A.2    Spring, D.R.3
  • 3
    • 79955554738 scopus 로고    scopus 로고
    • Quantifying structure and performance diversity for sets of small molecules comprising small-molecule screening collections
    • Clemons, P. A. et al. Quantifying structure and performance diversity for sets of small molecules comprising small-molecule screening collections. Proc. Natl Acad. Sci. USA 108, 6817-6822 (2011)
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , pp. 6817-6822
    • Clemons, P.A.1
  • 4
    • 78650459806 scopus 로고    scopus 로고
    • Small molecules of different origins have distinct distributions of structural complexity that correlate with protein-binding profiles
    • Clemons, P. A. et al. Small molecules of different origins have distinct distributions of structural complexity that correlate with protein-binding profiles. Proc. Natl Acad. Sci. USA 107, 18787-18792 (2010)
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 18787-18792
    • Clemons, P.A.1
  • 5
    • 33645521646 scopus 로고    scopus 로고
    • Natural products in combinatorial chemistry: An andrographolide-based library
    • Mang, C. et al. Natural products in combinatorial chemistry: An andrographolide-based library. J. Comb. Chem. 8, 268-274 (2006)
    • (2006) J. Comb. Chem. , vol.8 , pp. 268-274
    • Mang, C.1
  • 6
    • 36649030372 scopus 로고    scopus 로고
    • Natural products in parallel chemistry-novel 5-lipoxygenase inhibitors from BIOS-based libraries starting from a-santonin
    • Schwarz, O. et al. Natural products in parallel chemistry-novel 5-lipoxygenase inhibitors from BIOS-based libraries starting from a-santonin. J. Comb. Chem 9, 1104-1113 (2007)
    • (2007) J. Comb. Chem , vol.9 , pp. 1104-1113
    • Schwarz, O.1
  • 7
    • 34250164182 scopus 로고    scopus 로고
    • Identification of natural-product-derived inhibitors of 5-lipoxygenase activity by ligand-based virtual screening
    • Frank, L. et al. Identification of natural-product-derived inhibitors of 5-lipoxygenase activity by ligand-based virtual screening. J. Med. Chem. 50, 2640-2646 (2007)
    • (2007) J. Med. Chem. , vol.50 , pp. 2640-2646
    • Frank, L.1
  • 8
    • 0032569205 scopus 로고    scopus 로고
    • Stereoselective synthesis of over two million compounds having structural features both reminiscent of natural products and compatible with miniaturized cell-based assays
    • Tan, D. S., Foley, M. A., Shair, M. D. & Schreiber, S. L. Stereoselective synthesis of over two million compounds having structural features both reminiscent of natural products and compatible with miniaturized cell-based assays. J. Am. Chem. Soc. 120, 8565-8566 (1998)
    • (1998) J. Am. Chem. Soc. , vol.120 , pp. 8565-8566
    • Tan, D.S.1    Foley, M.A.2    Shair, M.D.3    Schreiber, S.L.4
  • 9
    • 34047238654 scopus 로고    scopus 로고
    • Ring-opening and ring-closing reactions of a shikimic acid-derived substrate leading to diverse small molecules
    • Miao, H. et al. Ring-opening and ring-closing reactions of a shikimic acid-derived substrate leading to diverse small molecules. J. Comb. Chem. 9, 245-253 (2007)
    • (2007) J. Comb. Chem. , vol.9 , pp. 245-253
    • Miao, H.1
  • 10
    • 33748581386 scopus 로고    scopus 로고
    • Site-selective derivatization and remodeling of erythromycin A by using simple peptide-based chiral catalysts
    • Lewis, C. A. & Miller, S. J. Site-selective derivatization and remodeling of erythromycin A by using simple peptide-based chiral catalysts. Angew. Chem. Int. Ed. 45, 5616-5619 (2006)
    • (2006) Angew. Chem. Int. Ed. , vol.45 , pp. 5616-5619
    • Lewis, C.A.1    Miller, S.J.2
  • 11
    • 70350491037 scopus 로고    scopus 로고
    • An approach to site-selective diversification of apoptolidin A with peptide-based catalysts
    • Lewis, C. A., Longcore, K. E., Miller, S. J. & Wender, P. A. An approach to site-selective diversification of apoptolidin A with peptide-based catalysts. J. Nat. Prod. 72, 1864-1869 (2009)
    • (2009) J. Nat. Prod. , vol.72 , pp. 1864-1869
    • Lewis, C.A.1    Longcore, K.E.2    Miller, S.J.3    Wender, P.A.4
  • 12
    • 0035979044 scopus 로고    scopus 로고
    • Unnatural natural products from the transannular cyclization of lathyrane diterpenes
    • Appendino, G., Tron, G. C., Jarevång, T. & Sterner, O. Unnatural natural products from the transannular cyclization of lathyrane diterpenes. Org. Lett. 3, 1609-1612 (2001)
    • (2001) Org. Lett. , vol.3 , pp. 1609-1612
    • Appendino, G.1    Tron, G.C.2    Jarevang, T.3    Sterner, O.4
  • 13
    • 34547206092 scopus 로고    scopus 로고
    • Iminonitroso Diels-Alder reactions for efficient derivatization and functionalization of complex diene-containing natural products
    • Li, F. et al. Iminonitroso Diels-Alder reactions for efficient derivatization and functionalization of complex diene-containing natural products. Org. Lett. 15, 2923-2926 (2007)
    • (2007) Org. Lett. , vol.15 , pp. 2923-2926
    • Li, F.1
  • 14
    • 45249102900 scopus 로고    scopus 로고
    • Evolution of natural product scaffolds by acyl-arylnitroso hetero-Diels-Alder reactions: New chemistry on piperine
    • Krchňák, V. et al. Evolution of natural product scaffolds by acyl-arylnitroso hetero-Diels-Alder reactions: New chemistry on piperine. J. Org. Chem. 73, 4559-4567 (2008)
    • (2008) J. Org. Chem. , Issue.73 , pp. 4559-4567
    • Krchňák, V.1
  • 15
    • 33846783006 scopus 로고    scopus 로고
    • Discovery of chemical reactions through multidimensional screening
    • Beeler, A. B., Su, S., Singleton, C. A. & Porco, J. A. Jr. Discovery of chemical reactions through multidimensional screening. J. Am. Chem. Soc. 129, 1413-1419 (2007)
    • (2007) J. Am. Chem. Soc. , vol.129 , pp. 1413-1419
    • Beeler, A.B.1    Su, S.2    Singleton, C.A.3    Porco Jr., J.A.4
  • 16
    • 61449202904 scopus 로고    scopus 로고
    • Reaction discovery employing macrocycles: Transannular cyclization of macrocyclic bis-lactams
    • Han, C. et al. Reaction discovery employing macrocycles: Transannular cyclization of macrocyclic bis-lactams. Org. Lett. 11, 413-416 (2009)
    • (2009) Org. Lett. , vol.11 , pp. 413-416
    • Han, C.1
  • 17
    • 77950240182 scopus 로고    scopus 로고
    • Synthesis of unique scaffolds via Diels-Alder cycloadditions of tetrasubstituted cyclohexadienes
    • Jones, A. L. & Snyder, J. K. Synthesis of unique scaffolds via Diels-Alder cycloadditions of tetrasubstituted cyclohexadienes. Org. Lett. 12, 1592-1595 (2010)
    • (2010) Org. Lett. , vol.12 , pp. 1592-1595
    • Jones, A.L.1    Snyder, J.K.2
  • 18
    • 77954559373 scopus 로고    scopus 로고
    • Skeletal diversity via cationic rearrangements of substituted dihydropyrans
    • Medeiros, M. R., Narayan, R. S., McDougal, N. T., Schaus, S. E. & Porco, J. A. Jr. Skeletal diversity via cationic rearrangements of substituted dihydropyrans. Org. Lett. 12, 3222-3225 (2010)
    • (2010) Org. Lett. , vol.12 , pp. 3222-3225
    • Medeiros, M.R.1    Narayan, R.S.2    McDougal, N.T.3    Schaus, S.E.4    Porco Jr., J.A.5
  • 19
    • 82055188244 scopus 로고
    • Fumagillin and preparation
    • Hanson, F. R. & Eble, T. E. Fumagillin and preparation. US patent 2,652,356 (1950)
    • (1950) US patent 2 , vol.652 , pp. 356
    • Hanson, F.R.1    Eble, T.E.2
  • 20
    • 0000230330 scopus 로고
    • The chemistry of fumagillin
    • Tarbell, D. S. et al. The chemistry of fumagillin. J. Am. Chem. Soc. 83, 3096-3113 (1961)
    • (1961) J. Am. Chem. Soc. , vol.83 , pp. 3096-3113
    • Tarbell, D.S.1
  • 21
    • 77950248572 scopus 로고    scopus 로고
    • Syntheses of fumagillin and ovalicin
    • Yamaguchi, J. & Hayashi, Y. Syntheses of fumagillin and ovalicin. Chem. Eur. J 16, 3884-3901 (2010)
    • (2010) Chem. Eur. J , vol.16 , pp. 3884-3901
    • Yamaguchi, J.1    Hayashi, Y.2
  • 22
    • 0025204095 scopus 로고
    • Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumor growth
    • Ingber, D. et al. Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumor growth. Nature 348, 555-557 (1990)
    • (1990) Nature , vol.348 , pp. 555-557
    • Ingber, D.1
  • 23
    • 0032515029 scopus 로고    scopus 로고
    • Structure of human methionine aminopeptidase-2 complexed with fumagillin
    • Liu, S., Widom, J., Kemp, C. W., Crews, C. M. & Clardy, J. Structure of human methionine aminopeptidase-2 complexed with fumagillin. Science 282, 1324-1327 (1998)
    • (1998) Science , vol.282 , pp. 1324-1327
    • Liu, S.1    Widom, J.2    Kemp, C.W.3    Crews, C.M.4    Clardy, J.5
  • 24
    • 33748850356 scopus 로고    scopus 로고
    • Fumarranol, a rearranged fumagillin analogue that inhibits angiogenesis in vivo
    • Lu, J., Chong, C. R., Hu, X. & Liu, J. O. Fumarranol, a rearranged fumagillin analogue that inhibits angiogenesis in vivo. J. Med. Chem. 49, 5645-5648 (2006)
    • (2006) J. Med. Chem. , vol.49 , pp. 5645-5648
    • Lu, J.1    Chong, C.R.2    Hu, X.3    Liu, J.O.4
  • 25
    • 0030601830 scopus 로고    scopus 로고
    • Importance of hydrophobic energy: Structural determination of a hypoglycemic drug of the meglitinide family by nuclear magnetic resonance and molecular modeling
    • Lins, L. et al. Importance of hydrophobic energy: Structural determination of a hypoglycemic drug of the meglitinide family by nuclear magnetic resonance and molecular modeling. Biochem. Pharmacol. 52, 1155-1168 (1996)
    • (1996) Biochem. Pharmacol. , vol.52 , pp. 1155-1168
    • Lins, L.1
  • 26
    • 0034103807 scopus 로고    scopus 로고
    • Multivariate data analysis using D-optimal designs, partial least squares, and response surface modeling: A directional approach for the analysis of farnesyltransferase inhibitors
    • Giraud, E. et al. Multivariate data analysis using D-optimal designs, partial least squares, and response surface modeling: A directional approach for the analysis of farnesyltransferase inhibitors. J. Med. Chem. 43, 1807-1816 (2000)
    • (2000) J. Med. Chem. , vol.43 , pp. 1807-1816
    • Giraud, E.1
  • 27
    • 65649132794 scopus 로고    scopus 로고
    • Potent, brain-penetrant, hydroisoindoline-based human neurokinin-1 receptor antagonists
    • Jiang, J. et al. Potent, brain-penetrant, hydroisoindoline-based human neurokinin-1 receptor antagonists. J. Med. Chem. 52, 3039-3046 (2009)
    • (2009) J. Med. Chem. , vol.52 , pp. 3039-3046
    • Jiang, J.1
  • 28
    • 6844258209 scopus 로고    scopus 로고
    • An enantioselective synthesis of cis-perhydroisoquinoline LY235959
    • Hansen, M. M. et al. An enantioselective synthesis of cis-perhydroisoquinoline LY235959. J. Org. Chem. 63, 775-785 (1998)
    • (1998) J. Org. Chem. , vol.63 , pp. 775-785
    • Hansen, M.M.1
  • 29
    • 35348836666 scopus 로고    scopus 로고
    • Cinnamoyl derivatives of 7a-aminomethyl-6,14-endoethanotetrahydrothebaine and 7a-aminomethyl-6,14-endoethanotetrahydrooripavine and related opioid ligands
    • Rennison, D. et al. Cinnamoyl derivatives of 7a-aminomethyl-6,14- endoethanotetrahydrothebaine and 7a-aminomethyl-6,14- endoethanotetrahydrooripavine and related opioid ligands. J. Med. Chem. 50, 5176-5182 (2007)
    • (2007) J. Med. Chem. , vol.50 , pp. 5176-5182
    • Rennison, D.1
  • 30
    • 77956162799 scopus 로고    scopus 로고
    • N-Alkyl-octhydroisoquinoline-1-one-8-carboxamides: Selective and nonbasic k-opioid receptor ligands
    • Frankowski, K. J. et al. N-Alkyl-octhydroisoquinoline-1-one-8- carboxamides: Selective and nonbasic k-opioid receptor ligands. ACS Med. Chem. Lett. 1, 189-193 (2010)
    • (2010) ACS Med. Chem. Lett. , vol.1 , pp. 189-193
    • Frankowski, K.J.1
  • 31
    • 33746606076 scopus 로고    scopus 로고
    • Ytterbium(III) triflate-catalyzed preparation of calix[ 4]resorcinarenes: Lewis-assisted Brønsted acidity
    • Barrett, A. G. M., Braddock, D. C., Henschke, J. C. &Walker, E. R. Ytterbium(III) triflate-catalyzed preparation of calix[4]resorcinarenes: Lewis-assisted Brønsted acidity. J. Chem. Soc. Perkin Trans. 1 873-878 (1999)
    • (1999) J. Chem. Soc. Perkin Trans. , vol.1 , pp. 873-878
    • Barrett, A.G.M.1    Braddock, D.C.2    Henschke, J.C.3    Walker, E.R.4
  • 32
    • 0348048819 scopus 로고    scopus 로고
    • On the role of triflic acid in the metal triflate-catalyzed acylation of alcohols
    • Dumeunier, R. & Markó, I. E. On the role of triflic acid in the metal triflate-catalyzed acylation of alcohols. Tetrahedron Lett. 45, 825-829 (2004)
    • (2004) Tetrahedron Lett. , vol.45 , pp. 825-829
    • Dumeunier, R.1    Markó, I.E.2
  • 33
    • 0028879832 scopus 로고
    • La(OTf)3-catalysed 6-endo epoxide opening of 4,5-epoxy-4-methoxymethyl-1- hexanols
    • Fujiwara, K., Tokiwano, T. & Murai, A. La(OTf)3-catalysed 6-endo epoxide opening of 4,5-epoxy-4-methoxymethyl-1-hexanols. Tetrahedron Lett. 36, 8063-8066 (1995)
    • (1995) Tetrahedron Lett. , vol.36 , pp. 8063-8066
    • Fujiwara, K.1    Tokiwano, T.2    Murai, A.3
  • 34
    • 0032576840 scopus 로고    scopus 로고
    • La(OTf)3-catalyzed 7-endo and 8-endo selective cyclizations of hydroxy epoxides
    • Fujiwara, K., Mishima, H., Amano, A., Tokiwano, T. & Murai, A. La(OTf)3- catalyzed 7-endo and 8-endo selective cyclizations of hydroxy epoxides. Tetrahedron Lett. 39, 393-396 (1998)
    • (1998) Tetrahedron Lett. , vol.39 , pp. 393-396
    • Fujiwara, K.1    Mishima, H.2    Amano, A.3    Tokiwano, T.4    Murai, A.5
  • 35
    • 0034602374 scopus 로고    scopus 로고
    • Oxygen-directed carbocyclizations of epoxides
    • Marson, C. M. Oxygen-directed carbocyclizations of epoxides. Tetrahedron 56, 8779-8794 (2000)
    • (2000) Tetrahedron , vol.56 , pp. 8779-8794
    • Marson, C.M.1
  • 36
    • 77953839242 scopus 로고    scopus 로고
    • Multidimensional screening and methodology development for condensations involving complex 1,2-diketones
    • Goodell, J. R., Leng, B., Snyder, T. K., Beeler, A. B. & Porco, J. A. Jr. Multidimensional screening and methodology development for condensations involving complex 1,2-diketones. Synthesis 2254-2270 (2010)
    • (2010) Synthesis , pp. 2254-2270
    • Goodell, J.R.1    Leng, B.2    Snyder, T.K.3    Beeler, A.B.4    Porco Jr., J.A.5
  • 37
    • 0242266514 scopus 로고    scopus 로고
    • Design, synthesis and evaluation of a series of novel fumagillin analogues
    • Fardis, M. et al. Design, synthesis and evaluation of a series of novel fumagillin analogues. Bioorg. Med. Chem. 11, 5051-5058 (2003)
    • (2003) Bioorg. Med. Chem. , vol.11 , pp. 5051-5058
    • Fardis, M.1
  • 38
    • 0347517817 scopus 로고    scopus 로고
    • Investigation of novel fumagillin analogues as angiogenesis inhibitors
    • Pyun, H.-J. et al. Investigation of novel fumagillin analogues as angiogenesis inhibitors. Bioorg. Med. Chem. Lett. 14, 91-94 (2004)
    • (2004) Bioorg. Med. Chem. Lett. , vol.14 , pp. 91-94
    • Pyun, H.-J.1
  • 39
    • 33750065139 scopus 로고    scopus 로고
    • Substituent activity relationship studies on new azolo benzoxazepinyl oxazolidinones
    • Das, J. et al. Substituent activity relationship studies on new azolo benzoxazepinyl oxazolidinones. Bioorg. Med. Chem. 14, 8032-8042 (2006)
    • (2006) Bioorg. Med. Chem. , vol.14 , pp. 8032-8042
    • Das, J.1
  • 40
    • 38949198338 scopus 로고    scopus 로고
    • Anticancer activity of 12,3,5-tetrahydro-4,1- benzoxazepine-3-yl)- pyrimidines and -purines against the MCF-7 cell line: Preliminary cDNA microarray studies
    • Díaz-Gavilán, M. et al. Anticancer activity of (1,2,3,5-tetrahydro-4,1- benzoxazepine-3-yl)-pyrimidines and -purines against the MCF-7 cell line: Preliminary cDNA microarray studies. Bioorg. Med. Chem. Lett. 18, 1457-1460 (2008)
    • (2008) Bioorg. Med. Chem. Lett. , vol.18 , pp. 1457-1460
    • Díaz-Gavilán, M.1
  • 41
    • 78650510611 scopus 로고    scopus 로고
    • New(RS)-benzoxazepin-purines with antitumor activity: The chiral switch from (RS)-2 6-dichloro-9-[1-(p-nitrobenzenesulfonyl)-1 2,3, 5-tetrahydro-4,1- benzoxazepin-3-yl]-9H-purine
    • López-Cara, L. C. et al. New(RS)-benzoxazepin-purines with antitumor activity: The chiral switch from (RS)-2,6-dichloro-9-[1-(p- nitrobenzenesulfonyl)-1,2,3, 5-tetrahydro-4,1-benzoxazepin-3-yl]-9H-purine. Eur. J. Med. Chem. 46, 249-258 (2011)
    • (2011) Eur. J. Med. Chem. , vol.46 , pp. 249-258
    • López-Cara, L.C.1
  • 42
    • 49849093426 scopus 로고    scopus 로고
    • PtII-catalyzed synthesis of 9-oxabicyclo[3.3.1]nona-2,6-dienes from 2-alkynyl-1-carbonylbenzenes and allylsilanes by an allylation/annulation cascade
    • Bhunia, S., Wang, K.-C. & Liu, R.-S. PtII-catalyzed synthesis of 9-oxabicyclo[3.3.1]nona-2,6-dienes from 2-alkynyl-1-carbonylbenzenes and allylsilanes by an allylation/annulation cascade. Angew. Chem. Int. Ed. 47, 5063-5066 (2008)
    • (2008) Angew. Chem. Int. Ed. , vol.47 , pp. 5063-5066
    • Bhunia, S.1    Wang, K.-C.2    Liu, R.-S.3
  • 43
    • 53549101621 scopus 로고    scopus 로고
    • Tandem intramolecular hydroalkoxylation-hydroarylation reactions: Synthesis of enantiopure benzofused cyclic ethers from the chiral pool
    • Barluenga, J. et al. Tandem intramolecular hydroalkoxylation- hydroarylation reactions: Synthesis of enantiopure benzofused cyclic ethers from the chiral pool. Chem. Eur J. 14, 4153-4156 (2008)
    • (2008) Chem. Eur J. , vol.14 , pp. 4153-4156
    • Barluenga, J.1
  • 44
    • 70350503905 scopus 로고    scopus 로고
    • Gold- or platinum-catalyzed cascade processes of alkynol derivatives involving hydroxylation reactions followed by Prins-type cyclizations
    • Barluenga, J., Fernández, A., Diéguez, A., Rodríguez, F. & Fañanás, F. J. Gold- or platinum-catalyzed cascade processes of alkynol derivatives involving hydroxylation reactions followed by Prins-type cyclizations. Chem. Eur. J. 15, 11660-11667 (2009)
    • (2009) Chem. Eur.J. , vol.15 , pp. 11660-11667
    • Barluenga, J.1    Fernández, A.2    Diéguez, A.3    Rodríguez, F.4    Fananás, F.J.5
  • 46
    • 34250881661 scopus 로고    scopus 로고
    • Effective, selective hydroalkoxylation/cyclization of alkynyl and allenyl alcohols mediated by lanthanide catalysts
    • Yu, X., Seo, S. Y. & Marks, T. J. Effective, selective hydroalkoxylation/cyclization of alkynyl and allenyl alcohols mediated by lanthanide catalysts. J. Am. Chem. Soc. 129, 7244-7245 (2007)
    • (2007) J. Am. Chem. Soc. , vol.129 , pp. 7244-7245
    • Yu, X.1    Seo, S.Y.2    Marks, T.J.3
  • 47
    • 77951847682 scopus 로고    scopus 로고
    • Atom-efficient carbon-oxygen bond formation process. DFT analysis of the intramolecular hydroalkoxylation/cyclization of alkynyl alcohols mediated by lanthanide catalysis
    • Motto, A., Fragalá, I. L. & Marks, T. J. Atom-efficient carbon-oxygen bond formation process. DFT analysis of the intramolecular hydroalkoxylation/cyclization of alkynyl alcohols mediated by lanthanide catalysis. Organometallics 29, 2004-2012 (2010)
    • (2010) Organometallics , vol.29 , pp. 2004-2012
    • Motto, A.1    Fragalá, I.L.2    Marks, T.J.3
  • 48
    • 71549163466 scopus 로고    scopus 로고
    • Synthesis of tetrahydropyrans and related heterocycles via Prins cyclization; extension to aza-Prins cyclization
    • Olier, C., Kaafarani, M., Gastaldi, S. & Bertrand, M. P. Synthesis of tetrahydropyrans and related heterocycles via Prins cyclization; extension to aza-Prins cyclization. Tetrahedron 66, 413-445 (2010).
    • (2010) Tetrahedron , vol.66 , pp. 413-445
    • Olier, C.1    Kaafarani, M.2    Gastaldi, S.3    Bertrand, M.P.4


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