메뉴 건너뛰기




Volumn 15, Issue 12, 2011, Pages 592-600

Optogenetic tools for analyzing the neural circuits of behavior

Author keywords

[No Author keywords available]

Indexed keywords

CELL TYPES; ELECTRICAL ACTIVITIES; NEURAL CIRCUITS;

EID: 81955164141     PISSN: 13646613     EISSN: 1879307X     Source Type: Journal    
DOI: 10.1016/j.tics.2011.10.003     Document Type: Review
Times cited : (217)

References (84)
  • 1
    • 79955684899 scopus 로고    scopus 로고
    • A history of optogenetics: the development of tools for controlling brain circuits with light
    • Boyden E.S. A history of optogenetics: the development of tools for controlling brain circuits with light. F1000 Biol. Rep. 2011, 3. 10.3410/B3-11.
    • (2011) F1000 Biol. Rep. , vol.3
    • Boyden, E.S.1
  • 2
    • 0037012096 scopus 로고    scopus 로고
    • Selective photostimulation of genetically chARGed neurons
    • Zemelman B.V., et al. Selective photostimulation of genetically chARGed neurons. Neuron 2002, 33:15-22.
    • (2002) Neuron , vol.33 , pp. 15-22
    • Zemelman, B.V.1
  • 3
    • 0025354171 scopus 로고
    • Local activation of contraction in isolated rat ventricular myocytes
    • O'Neill S.C., et al. Local activation of contraction in isolated rat ventricular myocytes. Am. J. Physiol. 1990, 258:C1165-C1168.
    • (1990) Am. J. Physiol. , vol.258
    • O'Neill, S.C.1
  • 4
    • 0029144210 scopus 로고
    • Determination of the chemical mechanism of neurotransmitter receptor-mediated reactions by rapid chemical kinetic methods
    • Hess G.P., et al. Determination of the chemical mechanism of neurotransmitter receptor-mediated reactions by rapid chemical kinetic methods. Ann. N. Y. Acad. Sci. 1995, 757:23-39.
    • (1995) Ann. N. Y. Acad. Sci. , vol.757 , pp. 23-39
    • Hess, G.P.1
  • 5
    • 0027480532 scopus 로고
    • Controlling cell chemistry with caged compounds
    • Adams S.R., Tsien R.Y. Controlling cell chemistry with caged compounds. Annu. Rev. Physiol. 1993, 55:755-784.
    • (1993) Annu. Rev. Physiol. , vol.55 , pp. 755-784
    • Adams, S.R.1    Tsien, R.Y.2
  • 6
    • 0028829059 scopus 로고
    • Confocal imaging and local photolysis of caged compounds: dual probes of synaptic function
    • Wang S.S., Augustine G.J. Confocal imaging and local photolysis of caged compounds: dual probes of synaptic function. Neuron 1995, 15:755-760.
    • (1995) Neuron , vol.15 , pp. 755-760
    • Wang, S.S.1    Augustine, G.J.2
  • 7
    • 0027220694 scopus 로고
    • Photostimulation using caged glutamate reveals functional circuitry in living brain slices
    • Callaway E.M., Katz L.C. Photostimulation using caged glutamate reveals functional circuitry in living brain slices. Proc. Natl. Acad. Sci. U.S.A. 1993, 90:7661-7665.
    • (1993) Proc. Natl. Acad. Sci. U.S.A. , vol.90 , pp. 7661-7665
    • Callaway, E.M.1    Katz, L.C.2
  • 8
    • 0026331484 scopus 로고
    • Regenerative release of calcium from functionally discrete subcellular stores by inositol trisphosphate
    • Parker I., Yao Y. Regenerative release of calcium from functionally discrete subcellular stores by inositol trisphosphate. Proc. Biol. Sci. 1991, 246:269-274.
    • (1991) Proc. Biol. Sci. , vol.246 , pp. 269-274
    • Parker, I.1    Yao, Y.2
  • 9
    • 0037417982 scopus 로고    scopus 로고
    • Photochemical gating of heterologous ion channels: remote control over genetically designated populations of neurons
    • Zemelman B.V., et al. Photochemical gating of heterologous ion channels: remote control over genetically designated populations of neurons. Proc. Natl. Acad. Sci. U.S.A. 2003, 100:1352-1357.
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , pp. 1352-1357
    • Zemelman, B.V.1
  • 10
    • 17044431846 scopus 로고    scopus 로고
    • Remote control of behavior through genetically targeted photostimulation of neurons
    • Lima S.Q., Miesenbock G. Remote control of behavior through genetically targeted photostimulation of neurons. Cell 2005, 121:141-152.
    • (2005) Cell , vol.121 , pp. 141-152
    • Lima, S.Q.1    Miesenbock, G.2
  • 11
    • 12344309164 scopus 로고    scopus 로고
    • Light-activated ion channels for remote control of neuronal firing
    • Banghart M., et al. Light-activated ion channels for remote control of neuronal firing. Nat. Neurosci. 2004, 7:1381-1386.
    • (2004) Nat. Neurosci. , vol.7 , pp. 1381-1386
    • Banghart, M.1
  • 12
    • 0345133280 scopus 로고    scopus 로고
    • Channelrhodopsin-2, a directly light-gated cation-selective membrane channel
    • Nagel G., et al. Channelrhodopsin-2, a directly light-gated cation-selective membrane channel. Proc. Natl. Acad. Sci. U.S.A. 2003, 100:13940-13945.
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , pp. 13940-13945
    • Nagel, G.1
  • 13
    • 26444621497 scopus 로고    scopus 로고
    • Millisecond-timescale, genetically targeted optical control of neural activity
    • Boyden E.S., et al. Millisecond-timescale, genetically targeted optical control of neural activity. Nat. Neurosci. 2005, 8:1263-1268.
    • (2005) Nat. Neurosci. , vol.8 , pp. 1263-1268
    • Boyden, E.S.1
  • 14
    • 79953230429 scopus 로고    scopus 로고
    • Ultra light-sensitive and fast neuronal activation with the Ca(2+)-permeable channelrhodopsin CatCh
    • Kleinlogel S., et al. Ultra light-sensitive and fast neuronal activation with the Ca(2+)-permeable channelrhodopsin CatCh. Nat. Neurosci. 2011, 14:513-518.
    • (2011) Nat. Neurosci. , vol.14 , pp. 513-518
    • Kleinlogel, S.1
  • 15
    • 29044433616 scopus 로고    scopus 로고
    • Light activation of channelrhodopsin-2 in excitable cells of Caenorhabditis elegans triggers rapid behavioral responses
    • Nagel G., et al. Light activation of channelrhodopsin-2 in excitable cells of Caenorhabditis elegans triggers rapid behavioral responses. Curr. Biol. 2005, 15:2279-2284.
    • (2005) Curr. Biol. , vol.15 , pp. 2279-2284
    • Nagel, G.1
  • 16
    • 79956332172 scopus 로고    scopus 로고
    • High-efficiency channelrhodopsins for fast neuronal stimulation at low light levels
    • Berndt A., et al. High-efficiency channelrhodopsins for fast neuronal stimulation at low light levels. Proc. Natl. Acad. Sci. U.S.A. 2011, 108:7595-7600.
    • (2011) Proc. Natl. Acad. Sci. U.S.A. , vol.108 , pp. 7595-7600
    • Berndt, A.1
  • 17
    • 65549100187 scopus 로고    scopus 로고
    • Characterization of engineered channelrhodopsin variants with improved properties and kinetics
    • Lin J.Y., et al. Characterization of engineered channelrhodopsin variants with improved properties and kinetics. Biophys. J. 2009, 96:1803-1814.
    • (2009) Biophys. J. , vol.96 , pp. 1803-1814
    • Lin, J.Y.1
  • 18
    • 65549147690 scopus 로고    scopus 로고
    • Molecular determinants differentiating photocurrent properties of two channelrhodopsins from Chlamydomonas
    • Wang H., et al. Molecular determinants differentiating photocurrent properties of two channelrhodopsins from Chlamydomonas. J. Biol. Chem. 2009, 284:5685-5696.
    • (2009) J. Biol. Chem. , vol.284 , pp. 5685-5696
    • Wang, H.1
  • 19
    • 77958583368 scopus 로고    scopus 로고
    • Opto-current-clamp actuation of cortical neurons using a strategically designed channelrhodopsin
    • Wen L., et al. Opto-current-clamp actuation of cortical neurons using a strategically designed channelrhodopsin. PLoS ONE 2010, 5:e12893.
    • (2010) PLoS ONE , vol.5
    • Wen, L.1
  • 20
    • 58849124558 scopus 로고    scopus 로고
    • Bi-stable neural state switches
    • Berndt A., et al. Bi-stable neural state switches. Nat. Neurosci. 2009, 12:229-234.
    • (2009) Nat. Neurosci. , vol.12 , pp. 229-234
    • Berndt, A.1
  • 21
    • 77649184827 scopus 로고    scopus 로고
    • Ultrafast optogenetic control
    • Gunaydin L.A., et al. Ultrafast optogenetic control. Nat. Neurosci. 2010, 13:387-392.
    • (2010) Nat. Neurosci. , vol.13 , pp. 387-392
    • Gunaydin, L.A.1
  • 22
    • 75349085542 scopus 로고    scopus 로고
    • Structural guidance of the photocycle of channelrhodopsin-2 by an interhelical hydrogen bond
    • Bamann C., et al. Structural guidance of the photocycle of channelrhodopsin-2 by an interhelical hydrogen bond. Biochemistry 2010, 49:267-278.
    • (2010) Biochemistry , vol.49 , pp. 267-278
    • Bamann, C.1
  • 23
    • 73849143150 scopus 로고    scopus 로고
    • High-performance genetically targetable optical neural silencing by light-driven proton pumps
    • Chow B.Y., et al. High-performance genetically targetable optical neural silencing by light-driven proton pumps. Nature 2010, 463:98-102.
    • (2010) Nature , vol.463 , pp. 98-102
    • Chow, B.Y.1
  • 24
    • 44349120639 scopus 로고    scopus 로고
    • Red-shifted optogenetic excitation: a tool for fast neural control derived from Volvox carteri
    • Zhang F., et al. Red-shifted optogenetic excitation: a tool for fast neural control derived from Volvox carteri. Nat. Neurosci. 2008, 11:631-633.
    • (2008) Nat. Neurosci. , vol.11 , pp. 631-633
    • Zhang, F.1
  • 25
    • 84855190225 scopus 로고    scopus 로고
    • New channelrhodopsin with a red-shifted spectrum and rapid kinetics from Mesostigma viride
    • Govorunova E.G., et al. New channelrhodopsin with a red-shifted spectrum and rapid kinetics from Mesostigma viride. MBio 2011, 2:e00115-e211.
    • (2011) MBio , vol.2
    • Govorunova, E.G.1
  • 26
    • 80052563319 scopus 로고    scopus 로고
    • Neocortical excitation/inhibition balance in information processing and social dysfunction
    • Yizhar O., et al. Neocortical excitation/inhibition balance in information processing and social dysfunction. Nature 2011, 477:171-178.
    • (2011) Nature , vol.477 , pp. 171-178
    • Yizhar, O.1
  • 27
    • 79957480743 scopus 로고    scopus 로고
    • Synthetic physiology strategies for adapting tools from nature for genetically targeted control of fast biological processes
    • Chow B.Y., et al. Synthetic physiology strategies for adapting tools from nature for genetically targeted control of fast biological processes. Methods Enzymol. 2011, 497:425-443.
    • (2011) Methods Enzymol. , vol.497 , pp. 425-443
    • Chow, B.Y.1
  • 28
    • 55849136898 scopus 로고    scopus 로고
    • Multiple-color optical activation, silencing, and desynchronization of neural activity, with single-spike temporal resolution
    • Han X., Boyden E.S. Multiple-color optical activation, silencing, and desynchronization of neural activity, with single-spike temporal resolution. PLoS ONE 2007, 2:e299.
    • (2007) PLoS ONE , vol.2
    • Han, X.1    Boyden, E.S.2
  • 29
    • 34247222730 scopus 로고    scopus 로고
    • Multimodal fast optical interrogation of neural circuitry
    • Zhang F., et al. Multimodal fast optical interrogation of neural circuitry. Nature 2007, 446:633-639.
    • (2007) Nature , vol.446 , pp. 633-639
    • Zhang, F.1
  • 30
    • 79960663747 scopus 로고    scopus 로고
    • Acute optogenetic silencing of orexin/hypocretin neurons induces slow-wave sleep in mice
    • Tsunematsu T., et al. Acute optogenetic silencing of orexin/hypocretin neurons induces slow-wave sleep in mice. J. Neurosci. 2011, 31:10529-10539.
    • (2011) J. Neurosci. , vol.31 , pp. 10529-10539
    • Tsunematsu, T.1
  • 31
    • 0035846990 scopus 로고    scopus 로고
    • Role of ER export signals in controlling surface potassium channel numbers
    • Ma D., et al. Role of ER export signals in controlling surface potassium channel numbers. Science 2001, 291:316-319.
    • (2001) Science , vol.291 , pp. 316-319
    • Ma, D.1
  • 32
    • 77950930288 scopus 로고    scopus 로고
    • Molecular and cellular approaches for diversifying and extending optogenetics
    • Gradinaru V., et al. Molecular and cellular approaches for diversifying and extending optogenetics. Cell 2010, 141:154-165.
    • (2010) Cell , vol.141 , pp. 154-165
    • Gradinaru, V.1
  • 33
    • 57049123832 scopus 로고    scopus 로고
    • ENpHR: a Natronomonas halorhodopsin enhanced for optogenetic applications
    • Gradinaru V., et al. eNpHR: a Natronomonas halorhodopsin enhanced for optogenetic applications. Brain Cell Biol. 2008, 36:129-139.
    • (2008) Brain Cell Biol. , vol.36 , pp. 129-139
    • Gradinaru, V.1
  • 34
    • 57049183577 scopus 로고    scopus 로고
    • Improved expression of halorhodopsin for light-induced silencing of neuronal activity
    • Zhao S., et al. Improved expression of halorhodopsin for light-induced silencing of neuronal activity. Brain Cell Biol. 2008, 36:141-154.
    • (2008) Brain Cell Biol. , vol.36 , pp. 141-154
    • Zhao, S.1
  • 35
    • 0027531526 scopus 로고
    • Light-driven proton or chloride pumping by halorhodopsin
    • Bamberg E., et al. Light-driven proton or chloride pumping by halorhodopsin. Proc. Natl. Acad. Sci. U.S.A. 1993, 90:639-643.
    • (1993) Proc. Natl. Acad. Sci. U.S.A. , vol.90 , pp. 639-643
    • Bamberg, E.1
  • 36
    • 0000948647 scopus 로고
    • The photocycle of the chloride pump halorhodopsin. I: azide-catalyzed deprotonation of the chromophore is a side reaction of photocycle intermediates inactivating the pump
    • Hegemann P., et al. The photocycle of the chloride pump halorhodopsin. I: azide-catalyzed deprotonation of the chromophore is a side reaction of photocycle intermediates inactivating the pump. EMBO J. 1985, 4:2347-2350.
    • (1985) EMBO J. , vol.4 , pp. 2347-2350
    • Hegemann, P.1
  • 37
    • 84862909320 scopus 로고    scopus 로고
    • A high-light sensitivity optical neural silencer: development and application to optogenetic control of non-human primate cortex
    • Han X., et al. A high-light sensitivity optical neural silencer: development and application to optogenetic control of non-human primate cortex. Front. Syst. Neurosci. 2011, 5-18. 10.3389/fnsys.2011.00018.
    • (2011) Front. Syst. Neurosci. , pp. 5-18
    • Han, X.1
  • 38
    • 29144480494 scopus 로고    scopus 로고
    • Fast noninvasive activation and inhibition of neural and network activity by vertebrate rhodopsin and green algae channelrhodopsin
    • Li X., et al. Fast noninvasive activation and inhibition of neural and network activity by vertebrate rhodopsin and green algae channelrhodopsin. Proc. Natl. Acad. Sci. U.S.A. 2005, 102:17816-17821.
    • (2005) Proc. Natl. Acad. Sci. U.S.A. , vol.102 , pp. 17816-17821
    • Li, X.1
  • 39
    • 79959514813 scopus 로고    scopus 로고
    • A synthetic optogenetic transcription device enhances blood-glucose homeostasis in mice
    • Ye H., et al. A synthetic optogenetic transcription device enhances blood-glucose homeostasis in mice. Science 2011, 332:1565-1568.
    • (2011) Science , vol.332 , pp. 1565-1568
    • Ye, H.1
  • 40
    • 0034602145 scopus 로고    scopus 로고
    • Distinct roles of the second and third cytoplasmic loops of bovine rhodopsin in G protein activation
    • Yamashita T., et al. Distinct roles of the second and third cytoplasmic loops of bovine rhodopsin in G protein activation. J. Biol. Chem. 2000, 275:34272-34279.
    • (2000) J. Biol. Chem. , vol.275 , pp. 34272-34279
    • Yamashita, T.1
  • 41
    • 0034927119 scopus 로고    scopus 로고
    • The second cytoplasmic loop of metabotropic glutamate receptor functions at the third loop position of rhodopsin
    • Yamashita T., et al. The second cytoplasmic loop of metabotropic glutamate receptor functions at the third loop position of rhodopsin. J. Biochem. 2001, 130:149-155.
    • (2001) J. Biochem. , vol.130 , pp. 149-155
    • Yamashita, T.1
  • 42
    • 52149097763 scopus 로고    scopus 로고
    • First cytoplasmic loop of glucagon-like peptide-1 receptor can function at the third cytoplasmic loop position of rhodopsin
    • Yamashita T., et al. First cytoplasmic loop of glucagon-like peptide-1 receptor can function at the third cytoplasmic loop position of rhodopsin. Photochem. Photobiol. 2008, 84:931-936.
    • (2008) Photochem. Photobiol. , vol.84 , pp. 931-936
    • Yamashita, T.1
  • 43
    • 65549086510 scopus 로고    scopus 로고
    • Temporally precise in vivo control of intracellular signalling
    • Airan R.D., et al. Temporally precise in vivo control of intracellular signalling. Nature 2009, 458:1025-1029.
    • (2009) Nature , vol.458 , pp. 1025-1029
    • Airan, R.D.1
  • 44
    • 70349967637 scopus 로고    scopus 로고
    • Induction of protein-protein interactions in live cells using light
    • Yazawa M., et al. Induction of protein-protein interactions in live cells using light. Nat. Biotechnol. 2009, 27:941-945.
    • (2009) Nat. Biotechnol. , vol.27 , pp. 941-945
    • Yazawa, M.1
  • 45
    • 78649714869 scopus 로고    scopus 로고
    • Rapid blue-light-mediated induction of protein interactions in living cells
    • Kennedy M.J., et al. Rapid blue-light-mediated induction of protein interactions in living cells. Nat. Methods 2010, 7:973-975.
    • (2010) Nat. Methods , vol.7 , pp. 973-975
    • Kennedy, M.J.1
  • 46
    • 58149333212 scopus 로고    scopus 로고
    • Light-induced rescue of breathing after spinal cord injury
    • Alilain W.J., et al. Light-induced rescue of breathing after spinal cord injury. J. Neurosci. 2008, 28:11862-11870.
    • (2008) J. Neurosci. , vol.28 , pp. 11862-11870
    • Alilain, W.J.1
  • 47
    • 36248996490 scopus 로고    scopus 로고
    • Neural substrates of awakening probed with optogenetic control of hypocretin neurons
    • Adamantidis A.R., et al. Neural substrates of awakening probed with optogenetic control of hypocretin neurons. Nature 2007, 450:420-424.
    • (2007) Nature , vol.450 , pp. 420-424
    • Adamantidis, A.R.1
  • 48
    • 38049061220 scopus 로고    scopus 로고
    • Sparse optical microstimulation in barrel cortex drives learned behaviour in freely moving mice
    • Huber D., et al. Sparse optical microstimulation in barrel cortex drives learned behaviour in freely moving mice. Nature 2008, 451:61-64.
    • (2008) Nature , vol.451 , pp. 61-64
    • Huber, D.1
  • 49
    • 48049090049 scopus 로고    scopus 로고
    • Escape behavior elicited by single, channelrhodopsin-2-evoked spikes in zebrafish somatosensory neurons
    • Douglass A.D., et al. Escape behavior elicited by single, channelrhodopsin-2-evoked spikes in zebrafish somatosensory neurons. Curr. Biol. 2008, 18:1133-1137.
    • (2008) Curr. Biol. , vol.18 , pp. 1133-1137
    • Douglass, A.D.1
  • 50
    • 35748963218 scopus 로고    scopus 로고
    • A toolbox for light control of Drosophila behaviors through Channelrhodopsin 2-mediated photoactivation of targeted neurons
    • Zhang W., et al. A toolbox for light control of Drosophila behaviors through Channelrhodopsin 2-mediated photoactivation of targeted neurons. Eur. J. Neurosci. 2007, 26:2405-2416.
    • (2007) Eur. J. Neurosci. , vol.26 , pp. 2405-2416
    • Zhang, W.1
  • 51
    • 44349103098 scopus 로고    scopus 로고
    • Light-activated channels targeted to ON bipolar cells restore visual function in retinal degeneration
    • Lagali P.S., et al. Light-activated channels targeted to ON bipolar cells restore visual function in retinal degeneration. Nat. Neurosci. 2008, 11:667-675.
    • (2008) Nat. Neurosci. , vol.11 , pp. 667-675
    • Lagali, P.S.1
  • 52
    • 57649185401 scopus 로고    scopus 로고
    • Patterned optical activation of retinal ganglion cells
    • Farah N., et al. Patterned optical activation of retinal ganglion cells. Conf. Proc. IEEE Eng. Med. Biol. Soc. 2007, 1:6368-6370.
    • (2007) Conf. Proc. IEEE Eng. Med. Biol. Soc. , vol.1 , pp. 6368-6370
    • Farah, N.1
  • 53
    • 33645974269 scopus 로고    scopus 로고
    • Ectopic expression of a microbial-type rhodopsin restores visual responses in mice with photoreceptor degeneration
    • Bi A., et al. Ectopic expression of a microbial-type rhodopsin restores visual responses in mice with photoreceptor degeneration. Neuron 2006, 50:23-33.
    • (2006) Neuron , vol.50 , pp. 23-33
    • Bi, A.1
  • 54
    • 34547133175 scopus 로고    scopus 로고
    • An optical neural interface: in vivo control of rodent motor cortex with integrated fiberoptic and optogenetic technology
    • Aravanis A.M., et al. An optical neural interface: in vivo control of rodent motor cortex with integrated fiberoptic and optogenetic technology. J. Neural Eng. 2007, 4:S143-S156.
    • (2007) J. Neural Eng. , vol.4
    • Aravanis, A.M.1
  • 55
    • 55849119222 scopus 로고    scopus 로고
    • Intestinal signaling to GABAergic neurons regulates a rhythmic behavior in Caenorhabditis elegans
    • Mahoney T.R., et al. Intestinal signaling to GABAergic neurons regulates a rhythmic behavior in Caenorhabditis elegans. Proc. Natl. Acad. Sci. U.S.A. 2008, 105:16350-16355.
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 16350-16355
    • Mahoney, T.R.1
  • 56
    • 53249100298 scopus 로고    scopus 로고
    • Optogenetic analysis of synaptic function
    • Liewald J.F., et al. Optogenetic analysis of synaptic function. Nat. Methods 2008, 5:895-902.
    • (2008) Nat. Methods , vol.5 , pp. 895-902
    • Liewald, J.F.1
  • 57
    • 33749837676 scopus 로고    scopus 로고
    • Light-induced activation of distinct modulatory neurons triggers appetitive or aversive learning in Drosophila larvae
    • Schroll C., et al. Light-induced activation of distinct modulatory neurons triggers appetitive or aversive learning in Drosophila larvae. Curr. Biol. 2006, 16:1741-1747.
    • (2006) Curr. Biol. , vol.16 , pp. 1741-1747
    • Schroll, C.1
  • 58
    • 30944451943 scopus 로고    scopus 로고
    • Kinetic evaluation of photosensitivity in genetically engineered neurons expressing green algae light-gated channels
    • Ishizuka T., et al. Kinetic evaluation of photosensitivity in genetically engineered neurons expressing green algae light-gated channels. Neurosci. Res. 2006, 54:85-94.
    • (2006) Neurosci. Res. , vol.54 , pp. 85-94
    • Ishizuka, T.1
  • 59
    • 34247548430 scopus 로고    scopus 로고
    • Channelrhodopsin-2-assisted circuit mapping of long-range callosal projections
    • Petreanu L., et al. Channelrhodopsin-2-assisted circuit mapping of long-range callosal projections. Nat. Neurosci. 2007, 10:663-668.
    • (2007) Nat. Neurosci. , vol.10 , pp. 663-668
    • Petreanu, L.1
  • 60
    • 75549086090 scopus 로고    scopus 로고
    • Activation of groups of excitatory neurons in the mammalian spinal cord or hindbrain evokes locomotion
    • Hagglund M., et al. Activation of groups of excitatory neurons in the mammalian spinal cord or hindbrain evokes locomotion. Nat. Neurosci. 2010, 13:246-252.
    • (2010) Nat. Neurosci. , vol.13 , pp. 246-252
    • Hagglund, M.1
  • 61
    • 34147126914 scopus 로고    scopus 로고
    • In vivo light-induced activation of neural circuitry in transgenic mice expressing channelrhodopsin-2
    • Arenkiel B.R., et al. In vivo light-induced activation of neural circuitry in transgenic mice expressing channelrhodopsin-2. Neuron 2007, 54:205-218.
    • (2007) Neuron , vol.54 , pp. 205-218
    • Arenkiel, B.R.1
  • 62
    • 78650678849 scopus 로고    scopus 로고
    • The columnar and laminar organization of inhibitory connections to neocortical excitatory cells
    • Katzel D., et al. The columnar and laminar organization of inhibitory connections to neocortical excitatory cells. Nat. Neurosci. 2011, 14:100-107.
    • (2011) Nat. Neurosci. , vol.14 , pp. 100-107
    • Katzel, D.1
  • 63
    • 65249104510 scopus 로고    scopus 로고
    • Millisecond-timescale optical control of neural dynamics in the nonhuman primate brain
    • Han X., et al. Millisecond-timescale optical control of neural dynamics in the nonhuman primate brain. Neuron 2009, 62:191-198.
    • (2009) Neuron , vol.62 , pp. 191-198
    • Han, X.1
  • 64
    • 49049099862 scopus 로고    scopus 로고
    • A FLEX switch targets Channelrhodopsin-2 to multiple cell types for imaging and long-range circuit mapping
    • Atasoy D., et al. A FLEX switch targets Channelrhodopsin-2 to multiple cell types for imaging and long-range circuit mapping. J. Neurosci. 2008, 28:7025-7030.
    • (2008) J. Neurosci. , vol.28 , pp. 7025-7030
    • Atasoy, D.1
  • 65
    • 44849103425 scopus 로고    scopus 로고
    • High-resolution labeling and functional manipulation of specific neuron types in mouse brain by Cre-activated viral gene expression
    • Kuhlman S.J., Huang Z.J. High-resolution labeling and functional manipulation of specific neuron types in mouse brain by Cre-activated viral gene expression. PLoS ONE 2008, 3:e2005.
    • (2008) PLoS ONE , vol.3
    • Kuhlman, S.J.1    Huang, Z.J.2
  • 66
    • 66249125042 scopus 로고    scopus 로고
    • Phasic firing in dopaminergic neurons is sufficient for behavioral conditioning
    • Tsai H.C., et al. Phasic firing in dopaminergic neurons is sufficient for behavioral conditioning. Science 2009, 324:1080-1084.
    • (2009) Science , vol.324 , pp. 1080-1084
    • Tsai, H.C.1
  • 67
    • 33847159648 scopus 로고    scopus 로고
    • Monosynaptic restriction of transsynaptic tracing from single, genetically targeted neurons
    • Wickersham I.R., et al. Monosynaptic restriction of transsynaptic tracing from single, genetically targeted neurons. Neuron 2007, 53:639-647.
    • (2007) Neuron , vol.53 , pp. 639-647
    • Wickersham, I.R.1
  • 68
    • 67650255311 scopus 로고    scopus 로고
    • PINP: a new method of tagging neuronal populations for identification during in vivo electrophysiological recording
    • Lima S.Q., et al. PINP: a new method of tagging neuronal populations for identification during in vivo electrophysiological recording. PLoS ONE 2009, 4:e6099.
    • (2009) PLoS ONE , vol.4
    • Lima, S.Q.1
  • 69
    • 79951848645 scopus 로고    scopus 로고
    • A lentiviral strategy for highly efficient retrograde gene transfer by pseudotyping with fusion envelope glycoprotein
    • Kato S., et al. A lentiviral strategy for highly efficient retrograde gene transfer by pseudotyping with fusion envelope glycoprotein. Hum. Gene Ther. 2011, 22:197-206.
    • (2011) Hum. Gene Ther. , vol.22 , pp. 197-206
    • Kato, S.1
  • 70
    • 80055103882 scopus 로고    scopus 로고
    • Scalable fluidic injector arrays for viral targeting of intact 3-D brain circuits
    • Chan S., et al. Scalable fluidic injector arrays for viral targeting of intact 3-D brain circuits. J. Vis. Exp. 2010, 35:e1489.
    • (2010) J. Vis. Exp. , vol.35
    • Chan, S.1
  • 71
    • 77950935182 scopus 로고    scopus 로고
    • Informational lesions: optical perturbation of spike timing and neural synchrony via microbial opsin gene fusions
    • Han X., et al. Informational lesions: optical perturbation of spike timing and neural synchrony via microbial opsin gene fusions. Front. Mol. Neurosci. 2009, 2-12. 10.3389/neuro.02.012.2009.
    • (2009) Front. Mol. Neurosci. , pp. 2-12
    • Han, X.1
  • 72
    • 67650487803 scopus 로고    scopus 로고
    • Faithful expression of multiple proteins via 2A-peptide self-processing: a versatile and reliable method for manipulating brain circuits
    • Tang W., et al. Faithful expression of multiple proteins via 2A-peptide self-processing: a versatile and reliable method for manipulating brain circuits. J. Neurosci. 2009, 29:8621-8629.
    • (2009) J. Neurosci. , vol.29 , pp. 8621-8629
    • Tang, W.1
  • 73
    • 39849100668 scopus 로고    scopus 로고
    • Fiber-coupled light-emitting diode for localized photostimulation of neurons expressing channelrhodopsin-2
    • Campagnola L., et al. Fiber-coupled light-emitting diode for localized photostimulation of neurons expressing channelrhodopsin-2. J. Neurosci. Methods 2008, 169:27-33.
    • (2008) J. Neurosci. Methods , vol.169 , pp. 27-33
    • Campagnola, L.1
  • 74
    • 61449224427 scopus 로고    scopus 로고
    • Automated light-based mapping of motor cortex by photoactivation of channelrhodopsin-2 transgenic mice
    • Ayling O.G., et al. Automated light-based mapping of motor cortex by photoactivation of channelrhodopsin-2 transgenic mice. Nat. Methods 2009, 6:219-224.
    • (2009) Nat. Methods , vol.6 , pp. 219-224
    • Ayling, O.G.1
  • 75
    • 79955139664 scopus 로고    scopus 로고
    • Mapping brain networks in awake mice using combined optical neural control and fMRI
    • Desai M., et al. Mapping brain networks in awake mice using combined optical neural control and fMRI. J. Neurophysiol. 2011, 105:1393-1405.
    • (2011) J. Neurophysiol. , vol.105 , pp. 1393-1405
    • Desai, M.1
  • 76
    • 77953423831 scopus 로고    scopus 로고
    • Global and local fMRI signals driven by neurons defined optogenetically by type and wiring
    • Lee J.H., et al. Global and local fMRI signals driven by neurons defined optogenetically by type and wiring. Nature 2010, 465:788-792.
    • (2010) Nature , vol.465 , pp. 788-792
    • Lee, J.H.1
  • 77
    • 79251478076 scopus 로고    scopus 로고
    • Multiwaveguide implantable probe for light delivery to sets of distributed brain targets
    • Zorzos A.N., et al. Multiwaveguide implantable probe for light delivery to sets of distributed brain targets. Opt. Lett. 2010, 35:4133-4135.
    • (2010) Opt. Lett. , vol.35 , pp. 4133-4135
    • Zorzos, A.N.1
  • 78
    • 79960783476 scopus 로고    scopus 로고
    • A wirelessly powered and controlled device for optical neural control of freely-behaving animals
    • Wentz C.T., et al. A wirelessly powered and controlled device for optical neural control of freely-behaving animals. J. Neural Eng. 2011, 8:046021.
    • (2011) J. Neural Eng. , vol.8 , pp. 046021
    • Wentz, C.T.1
  • 79
    • 0016058502 scopus 로고
    • Calculation of the maximum optical coupling efficiency into multimode optical waveguides
    • Hudson M.C. Calculation of the maximum optical coupling efficiency into multimode optical waveguides. Appl. Opt. 1974, 13:1029-1033.
    • (1974) Appl. Opt. , vol.13 , pp. 1029-1033
    • Hudson, M.C.1
  • 80
    • 79959497045 scopus 로고    scopus 로고
    • Physiology. Synthetic physiology
    • Chow B.Y., Boyden E.S. Physiology. Synthetic physiology. Science 2011, 332:1508-1509.
    • (2011) Science , vol.332 , pp. 1508-1509
    • Chow, B.Y.1    Boyden, E.S.2
  • 81
    • 79960635098 scopus 로고    scopus 로고
    • Excitatory transmission from the amygdala to nucleus accumbens facilitates reward seeking
    • Stuber G.D., et al. Excitatory transmission from the amygdala to nucleus accumbens facilitates reward seeking. Nature 2011, 475:377-380.
    • (2011) Nature , vol.475 , pp. 377-380
    • Stuber, G.D.1
  • 82
    • 77955457039 scopus 로고    scopus 로고
    • Optical activation of lateral amygdala pyramidal cells instructs associative fear learning
    • Johansen J.P., et al. Optical activation of lateral amygdala pyramidal cells instructs associative fear learning. Proc. Natl. Acad. Sci. U.S.A. 2010, 107:12692-12697.
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 12692-12697
    • Johansen, J.P.1
  • 83
    • 78149433114 scopus 로고    scopus 로고
    • Encoding of conditioned fear in central amygdala inhibitory circuits
    • Ciocchi S., et al. Encoding of conditioned fear in central amygdala inhibitory circuits. Nature 2010, 468:277-282.
    • (2010) Nature , vol.468 , pp. 277-282
    • Ciocchi, S.1
  • 84
    • 80052919009 scopus 로고    scopus 로고
    • Driving opposing behaviors with ensembles of piriform neurons
    • Choi G.B., et al. Driving opposing behaviors with ensembles of piriform neurons. Cell 2011, 146:1004-1015.
    • (2011) Cell , vol.146 , pp. 1004-1015
    • Choi, G.B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.