-
1
-
-
0033118334
-
Molecular tinkering of G proteincoupled receptors: An evolutionary success
-
Bockaert, J. and J. P. Pin (1999) Molecular tinkering of G proteincoupled receptors: An evolutionary success. EMBO J. 18, 1723-1729.
-
(1999)
EMBO J
, vol.18
, pp. 1723-1729
-
-
Bockaert, J.1
Pin, J.P.2
-
2
-
-
0034464742
-
Uncovering molecular mechanisms involved in activation ofGprotein-coupled receptors
-
Gether, U. (2000) Uncovering molecular mechanisms involved in activation ofGprotein-coupled receptors. Endocr. Rev. 21, 90-113.
-
(2000)
Endocr. Rev
, vol.21
, pp. 90-113
-
-
Gether, U.1
-
3
-
-
33947356279
-
G protein coupled receptor structure and activation
-
Kobilka, B. K. (2007) G protein coupled receptor structure and activation. Biochim. Biophys. Acta 1768, 794-807.
-
(2007)
Biochim. Biophys. Acta
, vol.1768
, pp. 794-807
-
-
Kobilka, B.K.1
-
4
-
-
0034604451
-
Crystal structure of rhodopsin: A G protein-coupled receptor
-
Palczewski, K., T. Kumasaka, T. Hori, C. A. Behnke, H. Motoshima, B. A. Fox, I. Le Trong, D. C. Teller, T. Okada, R. E. Stenkamp, M. Yamamoto and M. Miyano (2000) Crystal structure of rhodopsin: A G protein-coupled receptor. Science 289, 739-745.
-
(2000)
Science
, vol.289
, pp. 739-745
-
-
Palczewski, K.1
Kumasaka, T.2
Hori, T.3
Behnke, C.A.4
Motoshima, H.5
Fox, B.A.6
Le Trong, I.7
Teller, D.C.8
Okada, T.9
Stenkamp, R.E.10
Yamamoto, M.11
Miyano, M.12
-
5
-
-
0037197848
-
Functional role of internal water molecules in rhodopsin revealed by X-ray crystallography
-
Okada, T., Y. Fujiyoshi, M. Silow, J. Navarro, E. M. Landau and Y. Shichida (2002) Functional role of internal water molecules in rhodopsin revealed by X-ray crystallography. Proc. Natl Acad. Sci. USA 99, 5982-5987.
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 5982-5987
-
-
Okada, T.1
Fujiyoshi, Y.2
Silow, M.3
Navarro, J.4
Landau, E.M.5
Shichida, Y.6
-
6
-
-
0029907599
-
Requirement of rigid-body motion of transmembrane helices for light activation of rhodopsin
-
Farrens, D. L., C. Altenbach, K. Yang, W. L. Hubbell and H. G. Khorana (1996) Requirement of rigid-body motion of transmembrane helices for light activation of rhodopsin. Science 274, 768-770.
-
(1996)
Science
, vol.274
, pp. 768-770
-
-
Farrens, D.L.1
Altenbach, C.2
Yang, K.3
Hubbell, W.L.4
Khorana, H.G.5
-
7
-
-
0029778268
-
Rhodopsin activation blocked by metal-ion-binding sites linking transmembrane helices C and F
-
Sheikh, S. P., T. A. Zvyaga, O. Lichtarge, T. P. Sakmar and H. R. Bourne (1996) Rhodopsin activation blocked by metal-ion-binding sites linking transmembrane helices C and F. Nature 383, 347-350.
-
(1996)
Nature
, vol.383
, pp. 347-350
-
-
Sheikh, S.P.1
Zvyaga, T.A.2
Lichtarge, O.3
Sakmar, T.P.4
Bourne, H.R.5
-
8
-
-
0034602145
-
Distinct roles of the second and third cytoplasmic loops of bovine rhodopsin in G protein activation
-
Yamashita, T., A. Terakita and Y. Shichida (2000) Distinct roles of the second and third cytoplasmic loops of bovine rhodopsin in G protein activation. J. Biol. Chem. 275, 34272-34279.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 34272-34279
-
-
Yamashita, T.1
Terakita, A.2
Shichida, Y.3
-
9
-
-
0037016770
-
Functional interaction between bovine rhodopsin and G protein transducin
-
Terakita, A., T. Yamashita, N. Nimbari, D. Kojima and Y. Shichida (2002) Functional interaction between bovine rhodopsin and G protein transducin. J. Biol. Chem. 277, 40-46.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 40-46
-
-
Terakita, A.1
Yamashita, T.2
Nimbari, N.3
Kojima, D.4
Shichida, Y.5
-
10
-
-
14044276985
-
Light-driven activation of beta 2-adrenergic receptor signaling by a chimeric rhodopsin containing the beta 2-adrenergic receptor cytoplasmic loops
-
Kim, J. M., J. Hwa, P. Garriga, P. J. Reeves, U. L. RajBhandary and H. G. Khorana (2005) Light-driven activation of beta 2-adrenergic receptor signaling by a chimeric rhodopsin containing the beta 2-adrenergic receptor cytoplasmic loops. Biochemistry 44, 2284-2292.
-
(2005)
Biochemistry
, vol.44
, pp. 2284-2292
-
-
Kim, J.M.1
Hwa, J.2
Garriga, P.3
Reeves, P.J.4
RajBhandary, U.L.5
Khorana, H.G.6
-
11
-
-
0029589916
-
Identification of a receptor / G-protein contact site critical for signaling specificity and G-protein activation
-
Liu, J., B. R. Conklin, N. Blin, J. Yun and J. Wess (1995) Identification of a receptor / G-protein contact site critical for signaling specificity and G-protein activation. Proc. Natl Acad. Sci. USA 92, 11642-11646.
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 11642-11646
-
-
Liu, J.1
Conklin, B.R.2
Blin, N.3
Yun, J.4
Wess, J.5
-
12
-
-
0028912366
-
Structural basis of G protein specificity of human endothelin receptors. A study with endothelin A/B chimeras
-
Takagi, Y., H. Ninomiya, A. Sakamoto, S. Miwa and T. Masaki (1995) Structural basis of G protein specificity of human endothelin receptors. A study with endothelin A/B chimeras. J. Biol. Chem. 270, 10072-10078.
-
(1995)
J. Biol. Chem
, vol.270
, pp. 10072-10078
-
-
Takagi, Y.1
Ninomiya, H.2
Sakamoto, A.3
Miwa, S.4
Masaki, T.5
-
13
-
-
0029993115
-
Chimeric mutagenesis of putative G-protein coupling domains of the alpha2A-adrenergic receptor. Localization of two redundant and fully competent Gi coupling domains
-
Eason, M. G. and S. B. Liggett (1996) Chimeric mutagenesis of putative G-protein coupling domains of the alpha2A-adrenergic receptor. Localization of two redundant and fully competent Gi coupling domains. J. Biol. Chem. 271, 12826-12832.
-
(1996)
J. Biol. Chem
, vol.271
, pp. 12826-12832
-
-
Eason, M.G.1
Liggett, S.B.2
-
14
-
-
0029991991
-
Different single receptor domains determine the distinct G protein coupling profiles of members of the vasopressin receptor family
-
Liu, J. and J. Wess (1996) Different single receptor domains determine the distinct G protein coupling profiles of members of the vasopressin receptor family. J. Biol. Chem. 271, 8772-8778.
-
(1996)
J. Biol. Chem
, vol.271
, pp. 8772-8778
-
-
Liu, J.1
Wess, J.2
-
15
-
-
0034927119
-
The second cytoplasmic loop of metabotropic glutamate receptor functions at the third loop position of rhodopsin
-
Yamashita, T., A. Terakita and Y. Shichida (2001) The second cytoplasmic loop of metabotropic glutamate receptor functions at the third loop position of rhodopsin. J. Biochem. (Tokyo) 130, 149-155.
-
(2001)
J. Biochem. (Tokyo)
, vol.130
, pp. 149-155
-
-
Yamashita, T.1
Terakita, A.2
Shichida, Y.3
-
16
-
-
0028012253
-
Domains involved in the specificity of G protein activation in phospholipase C-coupled metabotropic glutamate receptors
-
Pin, J. P., C. Joly, S. F. Heinemann and J. Bockaert (1994) Domains involved in the specificity of G protein activation in phospholipase C-coupled metabotropic glutamate receptors. EMBO J. 13, 342-348.
-
(1994)
EMBO J
, vol.13
, pp. 342-348
-
-
Pin, J.P.1
Joly, C.2
Heinemann, S.F.3
Bockaert, J.4
-
17
-
-
0030050977
-
The second intracellular loop of metabotropic glutamate receptor 1 cooperates with the other intracellular domains to control coupling to G-proteins
-
Gomeza, J., C. Joly, R. Kuhn, T. Knopfel, J. Bockaert and J. P. Pin (1996) The second intracellular loop of metabotropic glutamate receptor 1 cooperates with the other intracellular domains to control coupling to G-proteins. J. Biol. Chem. 271, 2199-2205.
-
(1996)
J. Biol. Chem
, vol.271
, pp. 2199-2205
-
-
Gomeza, J.1
Joly, C.2
Kuhn, R.3
Knopfel, T.4
Bockaert, J.5
Pin, J.P.6
-
18
-
-
0042317114
-
The second intracellular loop of metabotropic glutamate receptors recognizes C-termini of G protein alpha-subunits
-
Havlickova, M., J. Blahos, I. Brabet, J. F. Liu, B. Hruskova, L. Prezeau and J. P. Pin (2003) The second intracellular loop of metabotropic glutamate receptors recognizes C-termini of G protein alpha-subunits. J. Biol. Chem. 278, 35063-35070.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 35063-35070
-
-
Havlickova, M.1
Blahos, J.2
Brabet, I.3
Liu, J.F.4
Hruskova, B.5
Prezeau, L.6
Pin, J.P.7
-
19
-
-
0030908617
-
Water and peptide backbone structure in the active center of bovine rhodopsin
-
Nagata, T., A. Terakita, H. Kandori, D. Kojima, Y. Shichida and A. Maeda (1997) Water and peptide backbone structure in the active center of bovine rhodopsin. Biochemistry 36, 6164-6170.
-
(1997)
Biochemistry
, vol.36
, pp. 6164-6170
-
-
Nagata, T.1
Terakita, A.2
Kandori, H.3
Kojima, D.4
Shichida, Y.5
Maeda, A.6
-
20
-
-
0030671441
-
Presence of two rhodopsin intermediates responsible for transducin activation
-
Tachibanaki, S., H. Imai, T. Mizukami, T. Okada, Y. Imamoto, T. Matsuda, Y. Fukada, A. Terakita and Y. Shichida (1997) Presence of two rhodopsin intermediates responsible for transducin activation. Biochemistry 36, 14173-14180.
-
(1997)
Biochemistry
, vol.36
, pp. 14173-14180
-
-
Tachibanaki, S.1
Imai, H.2
Mizukami, T.3
Okada, T.4
Imamoto, Y.5
Matsuda, T.6
Fukada, Y.7
Terakita, A.8
Shichida, Y.9
-
21
-
-
0028068329
-
Purification and separation of closely related members of pertussis toxin-substrate G proteins
-
Katada, T., K. Kontani, A. Inanobe, I. Kobayashi, Y. Ohoka, H. Nishina and K. Takahashi (1994) Purification and separation of closely related members of pertussis toxin-substrate G proteins. Methods Enzymol. 237, 131-139.
-
(1994)
Methods Enzymol
, vol.237
, pp. 131-139
-
-
Katada, T.1
Kontani, K.2
Inanobe, A.3
Kobayashi, I.4
Ohoka, Y.5
Nishina, H.6
Takahashi, K.7
-
22
-
-
0028048171
-
Expression of Gprotein alpha subunits in Escherichia coli
-
Lee, E., M. E. Linder and A. G. Gilman (1994) Expression of Gprotein alpha subunits in Escherichia coli. Methods Enzymol. 237, 146-164.
-
(1994)
Methods Enzymol
, vol.237
, pp. 146-164
-
-
Lee, E.1
Linder, M.E.2
Gilman, A.G.3
-
23
-
-
0032489519
-
Role of the second and third intracellular loops of metabotropic glutamate receptors in mediating dual signal transduction activation
-
Francesconi, A. and R. M. Duvoisin (1998) Role of the second and third intracellular loops of metabotropic glutamate receptors in mediating dual signal transduction activation. J. Biol. Chem. 273, 5615-5624.
-
(1998)
J. Biol. Chem
, vol.273
, pp. 5615-5624
-
-
Francesconi, A.1
Duvoisin, R.M.2
-
24
-
-
5444224320
-
A novel constitutively active mutation in the second cytoplasmic loop of metabotropic glutamate receptor
-
Yamashita, T., T. Kai, A. Terakita and Y. Shichida (2004) A novel constitutively active mutation in the second cytoplasmic loop of metabotropic glutamate receptor. J. Neurochem. 91, 484-492.
-
(2004)
J. Neurochem
, vol.91
, pp. 484-492
-
-
Yamashita, T.1
Kai, T.2
Terakita, A.3
Shichida, Y.4
-
25
-
-
0026209385
-
Rhodopsin mutations in autosomal dominant retinitis pigmentosa
-
Sung, C. H., C. M. Davenport, J. C. Hennessey, I. H. Maumenee, S. G. Jacobson, J. R. Heckenlively, R. Nowakowski, G. Fishman, P. Gouras and J. Nathans (1991) Rhodopsin mutations in autosomal dominant retinitis pigmentosa. Proc. Natl Acad. Sci. USA 88, 6481-6485.
-
(1991)
Proc. Natl Acad. Sci. USA
, vol.88
, pp. 6481-6485
-
-
Sung, C.H.1
Davenport, C.M.2
Hennessey, J.C.3
Maumenee, I.H.4
Jacobson, S.G.5
Heckenlively, J.R.6
Nowakowski, R.7
Fishman, G.8
Gouras, P.9
Nathans, J.10
-
26
-
-
0032941026
-
Pancreatic glucagon-like peptide-1 receptor couples to multiple G proteins and activates mitogen-activated protein kinase pathways in Chinese hamster ovary cells
-
Montrose-Rafizadeh, C., P. Avdonin, M. J. Garant, B. D. Rodgers, S. Kole, H. Yang, M. A. Levine, W. Schwindinger and M. Bernier (1999) Pancreatic glucagon-like peptide-1 receptor couples to multiple G proteins and activates mitogen-activated protein kinase pathways in Chinese hamster ovary cells. Endocrinology 140, 1132-1140.
-
(1999)
Endocrinology
, vol.140
, pp. 1132-1140
-
-
Montrose-Rafizadeh, C.1
Avdonin, P.2
Garant, M.J.3
Rodgers, B.D.4
Kole, S.5
Yang, H.6
Levine, M.A.7
Schwindinger, W.8
Bernier, M.9
-
27
-
-
0032410647
-
Protean effects of a natural peptide agonist of the G protein-coupled secretin receptor demonstrated by receptor mutagenesis
-
Ganguli, S. C., C. G. Park, M. H. Holtmann, E. M. Hadac, T. P. Kenakin and L. J. Miller (1998) Protean effects of a natural peptide agonist of the G protein-coupled secretin receptor demonstrated by receptor mutagenesis. J. Pharmacol. Exp. Ther. 286, 593-598.
-
(1998)
J. Pharmacol. Exp. Ther
, vol.286
, pp. 593-598
-
-
Ganguli, S.C.1
Park, C.G.2
Holtmann, M.H.3
Hadac, E.M.4
Kenakin, T.P.5
Miller, L.J.6
-
28
-
-
0025036350
-
Rhodopsin mutants that bind but fail to activate transducin
-
Franke, R. R., B. Konig, T. P. Sakmar, H. G. Khorana and K. P. Hofmann (1990) Rhodopsin mutants that bind but fail to activate transducin. Science 250, 123-125.
-
(1990)
Science
, vol.250
, pp. 123-125
-
-
Franke, R.R.1
Konig, B.2
Sakmar, T.P.3
Khorana, H.G.4
Hofmann, K.P.5
-
29
-
-
0028946950
-
Characterization of rhodopsin mutants that bind transducin but fail to induce GTP nucleotide uptake. Classification of mutant pigments by fluorescence, nucleotide release, and flash-induced light-scattering assays
-
Ernst, O. P., K. P. Hofmann and T. P. Sakmar (1995) Characterization of rhodopsin mutants that bind transducin but fail to induce GTP nucleotide uptake. Classification of mutant pigments by fluorescence, nucleotide release, and flash-induced light-scattering assays. J. Biol. Chem. 270, 10580-10586.
-
(1995)
J. Biol. Chem
, vol.270
, pp. 10580-10586
-
-
Ernst, O.P.1
Hofmann, K.P.2
Sakmar, T.P.3
-
30
-
-
0030990139
-
Scanning of the glucagon-like peptide-1 receptor localizes G protein-activating determinants primarily to the N terminus of the third intracellular loop
-
Mathi, S. K., Y. Chan, X. Li and M. B. Wheeler (1997) Scanning of the glucagon-like peptide-1 receptor localizes G protein-activating determinants primarily to the N terminus of the third intracellular loop. Mol. Endocrinol. 11, 424-432.
-
(1997)
Mol. Endocrinol
, vol.11
, pp. 424-432
-
-
Mathi, S.K.1
Chan, Y.2
Li, X.3
Wheeler, M.B.4
-
31
-
-
0033516651
-
Two cytoplasmic loops of the glucagon receptor are required to elevate cAMP or intracellular calcium
-
Cypess, A. M., C. G. Unson, Wu C. R. and T. P. Sakmar (1999) Two cytoplasmic loops of the glucagon receptor are required to elevate cAMP or intracellular calcium. J. Biol. Chem. 274, 19455-19464.
-
(1999)
J. Biol. Chem
, vol.274
, pp. 19455-19464
-
-
Cypess, A.M.1
Unson, C.G.2
Wu, C.R.3
Sakmar, T.P.4
-
32
-
-
33751090467
-
Diverse functional motifs within the three intracellular loops of the CGRP1 receptor
-
Conner, A. C., J. Simms, M. T. Conner, D. L. Wootten, M. Wheatley and D. R. Poyner (2006) Diverse functional motifs within the three intracellular loops of the CGRP1 receptor. Biochemistry 45, 12976-12985.
-
(2006)
Biochemistry
, vol.45
, pp. 12976-12985
-
-
Conner, A.C.1
Simms, J.2
Conner, M.T.3
Wootten, D.L.4
Wheatley, M.5
Poyner, D.R.6
-
33
-
-
4644359972
-
Mutations in the carboxyterminus of the third intracellular loop of the human recombinant VPAC1 receptor impair VIP-stimulated [Ca2 + ]i increase but not adenylate cyclase stimulation
-
Langer, I. and P. Robberecht (2005) Mutations in the carboxyterminus of the third intracellular loop of the human recombinant VPAC1 receptor impair VIP-stimulated [Ca2 + ]i increase but not adenylate cyclase stimulation. Cell. Signal. 17, 17-24.
-
(2005)
Cell. Signal
, vol.17
, pp. 17-24
-
-
Langer, I.1
Robberecht, P.2
-
34
-
-
0029013212
-
Expression of two human skeletal calcitonin receptor isoforms cloned from a giant cell tumor of bone. The first intracellular domain modulates ligand binding and signal transduction
-
Gorn, A. H., S. M. Rudolph, M. R. Flannery, C. C. Morton, S. Weremowicz, T. Z. Wang, S. M. Krane and S. R. Goldring (1995) Expression of two human skeletal calcitonin receptor isoforms cloned from a giant cell tumor of bone. The first intracellular domain modulates ligand binding and signal transduction. J. Clin. Invest. 95, 2680-2691.
-
(1995)
J. Clin. Invest
, vol.95
, pp. 2680-2691
-
-
Gorn, A.H.1
Rudolph, S.M.2
Flannery, M.R.3
Morton, C.C.4
Weremowicz, S.5
Wang, T.Z.6
Krane, S.M.7
Goldring, S.R.8
-
35
-
-
0037471354
-
Different role of intracellular loops of glucagon-like peptide-1 receptor in G-protein coupling
-
Bavec, A., M. Hallbrink, U. Langel and M. Zorko (2003) Different role of intracellular loops of glucagon-like peptide-1 receptor in G-protein coupling. Regul. Pept. 111, 137-144.
-
(2003)
Regul. Pept
, vol.111
, pp. 137-144
-
-
Bavec, A.1
Hallbrink, M.2
Langel, U.3
Zorko, M.4
|