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Volumn 6, Issue 6, 2011, Pages 487-495

The role of Th17 lymphocytes in the autoimmune and chronic inflammatory diseases

Author keywords

Cytokines; Inflammatory diseases; Th 17

Indexed keywords

INTERLEUKIN 17;

EID: 81955160918     PISSN: 18280447     EISSN: 19709366     Source Type: Journal    
DOI: 10.1007/s11739-011-0517-7     Document Type: Review
Times cited : (109)

References (49)
  • 1
    • 67650657499 scopus 로고    scopus 로고
    • Interleukin-17 and systemic lupus erythematosus: current concepts
    • Nalbandian A, Crispín JC, Tsokos GC (2009) Interleukin-17 and systemic lupus erythematosus: current concepts. Clin Exp Immunol 157(2): 209-215.
    • (2009) Clin Exp Immunol , vol.157 , Issue.2 , pp. 209-215
    • Nalbandian, A.1    Crispín, J.C.2    Tsokos, G.C.3
  • 2
    • 33847206969 scopus 로고    scopus 로고
    • IL-17 family cytokines and the expanding diversity of effector T cell lineages
    • Weaver CT, Hatton RD, Mangan PR, Harrington LE (2007) IL-17 family cytokines and the expanding diversity of effector T cell lineages. Annu Rev Immunol 25: 821-852.
    • (2007) Annu Rev Immunol , vol.25 , pp. 821-852
    • Weaver, C.T.1    Hatton, R.D.2    Mangan, P.R.3    Harrington, L.E.4
  • 3
    • 39449087338 scopus 로고    scopus 로고
    • Th17 cells: effector cells with inflammatory properties
    • Korn T, Oukka M, Kuchroo VK, Bettelli E (2007) Th17 cells: effector cells with inflammatory properties. Semin Immunol 19: 362-371.
    • (2007) Semin Immunol , vol.19 , pp. 362-371
    • Korn, T.1    Oukka, M.2    Kuchroo, V.K.3    Bettelli, E.4
  • 5
    • 65549098640 scopus 로고    scopus 로고
    • CD4 T-cell differentiation and inflammatory bowel disease
    • Zenewicz LA, Antov A, Flavell RA (2009) CD4 T-cell differentiation and inflammatory bowel disease. Trends Mol Med 15(5): 199-207.
    • (2009) Trends Mol Med , vol.15 , Issue.5 , pp. 199-207
    • Zenewicz, L.A.1    Antov, A.2    Flavell, R.A.3
  • 6
    • 0037449737 scopus 로고    scopus 로고
    • Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17
    • Aggarwal S, Ghilardi N, Xie MH, de Sauvage FJ, Gurney AL (2003) Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17. J Biol Chem 278: 1910-1914.
    • (2003) J Biol Chem , vol.278 , pp. 1910-1914
    • Aggarwal, S.1    Ghilardi, N.2    Xie, M.H.3    de Sauvage, F.J.4    Gurney, A.L.5
  • 7
    • 49249135394 scopus 로고    scopus 로고
    • Human interleukin 17-producing cells originate from a CD161+ CD4+ T cell precursor
    • Cosmi L, De Palma R, Santarlasci V, Maggi L, Capone M, Frosali F et al (2008) Human interleukin 17-producing cells originate from a CD161+ CD4+ T cell precursor. J Exp Med 205(8): 1903-1916.
    • (2008) J Exp Med , vol.205 , Issue.8 , pp. 1903-1916
    • Cosmi, L.1    de Palma, R.2    Santarlasci, V.3    Maggi, L.4    Capone, M.5    Frosali, F.6
  • 8
    • 70349571184 scopus 로고    scopus 로고
    • Do studies in humans better depict Th17 cells?
    • Annunziato F, Romagnani S (2009) Do studies in humans better depict Th17 cells? Blood 114(11): 2213-2219.
    • (2009) Blood , vol.114 , Issue.11 , pp. 2213-2219
    • Annunziato, F.1    Romagnani, S.2
  • 9
    • 34548125305 scopus 로고    scopus 로고
    • Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells
    • Acosta-Rodriguez EV, Napolitani G, Lanzavecchia A, Sallusto F (2007) Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells. Nat Immunol l8(9): 942-949.
    • (2007) Nat Immunol , vol.l8 , Issue.9 , pp. 942-949
    • Acosta-Rodriguez, E.V.1    Napolitani, G.2    Lanzavecchia, A.3    Sallusto, F.4
  • 10
    • 44049104564 scopus 로고    scopus 로고
    • The differentiation of human Th17 cells requires transforming growth factor-beta and induction of the nuclear receptor ROR gamma t
    • Manel N, Unutmaz D, Littman DR (2008) The differentiation of human Th17 cells requires transforming growth factor-beta and induction of the nuclear receptor ROR gamma t. Nat Immunol 9(6): 641-649.
    • (2008) Nat Immunol , vol.9 , Issue.6 , pp. 641-649
    • Manel, N.1    Unutmaz, D.2    Littman, D.R.3
  • 11
    • 44049102724 scopus 로고    scopus 로고
    • A critical function for transforming growth factor-beta, interleukin-23 and proinflammatory cytokines in driving and modulating human Th17 responses
    • Volpe E, Servant N, Zollinger R, Bogiatzi SI, Hupé P, Barillot E et al (2008) A critical function for transforming growth factor-beta, interleukin-23 and proinflammatory cytokines in driving and modulating human Th17 responses. Nat Immunol 9(6): 650-657.
    • (2008) Nat Immunol , vol.9 , Issue.6 , pp. 650-657
    • Volpe, E.1    Servant, N.2    Zollinger, R.3    Bogiatzi, S.I.4    Hupé, P.5    Barillot, E.6
  • 12
    • 47549112840 scopus 로고    scopus 로고
    • IL-21 and TGF-beta are required for differentiation of human T(H)17 cells
    • Yang L, Anderson DE, Baecher-Allan C, Hastings WD, Bettelli E, Oukka M et al (2008) IL-21 and TGF-beta are required for differentiation of human T(H)17 cells. Nature 454(7202): 350-352.
    • (2008) Nature , vol.454 , Issue.7202 , pp. 350-352
    • Yang, L.1    Anderson, D.E.2    Baecher-Allan, C.3    Hastings, W.D.4    Bettelli, E.5    Oukka, M.6
  • 13
    • 41549135632 scopus 로고    scopus 로고
    • The biological functions of T helper 17 cell effector cytokines in inflammation
    • Ouyang W, Kolls JK, Zheng Y (2008) The biological functions of T helper 17 cell effector cytokines in inflammation. Immunity 28(4): 454-467.
    • (2008) Immunity , vol.28 , Issue.4 , pp. 454-467
    • Ouyang, W.1    Kolls, J.K.2    Zheng, Y.3
  • 14
    • 69249212309 scopus 로고    scopus 로고
    • Vdelta1 T lymphocytes producing IFN-gamma and IL-17 are expanded in HIV-1-infected patients and respond to Candida albicans
    • Fenoglio D, Poggi A, Catellani S, Battaglia F, Ferrera A, Setti M et al (2009) Vdelta1 T lymphocytes producing IFN-gamma and IL-17 are expanded in HIV-1-infected patients and respond to Candida albicans. Blood 113(26): 6611-6618.
    • (2009) Blood , vol.113 , Issue.26 , pp. 6611-6618
    • Fenoglio, D.1    Poggi, A.2    Catellani, S.3    Battaglia, F.4    Ferrera, A.5    Setti, M.6
  • 15
    • 33749318470 scopus 로고    scopus 로고
    • Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides
    • Liang SC, Tan XY, Luxenberg DP, Karim R, Dunussi-Joannopoulos K, Collins M et al (2006) Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides. J Exp Med 203: 2271-2279.
    • (2006) J Exp Med , vol.203 , pp. 2271-2279
    • Liang, S.C.1    Tan, X.Y.2    Luxenberg, D.P.3    Karim, R.4    Dunussi-Joannopoulos, K.5    Collins, M.6
  • 16
    • 65449124271 scopus 로고    scopus 로고
    • Regulatory mechanisms of immune responses to intestinal bacteria
    • Honda K, Takeda K (2009) Regulatory mechanisms of immune responses to intestinal bacteria. Mucosal Immunol 2(3): 187-196.
    • (2009) Mucosal Immunol , vol.2 , Issue.3 , pp. 187-196
    • Honda, K.1    Takeda, K.2
  • 17
    • 77957032994 scopus 로고    scopus 로고
    • Th17 plasticity in human autoimmune arthritis is driven by the inflammatory environment
    • Nistala K, Adams S, Cambrook H, Ursu S, Olivito B, de Jager W et al (2010) Th17 plasticity in human autoimmune arthritis is driven by the inflammatory environment. Proc Natl Acad Sci USA 107(33): 14751-14756.
    • (2010) Proc Natl Acad Sci USA , vol.107 , Issue.33 , pp. 14751-14756
    • Nistala, K.1    Adams, S.2    Cambrook, H.3    Ursu, S.4    Olivito, B.5    de Jager, W.6
  • 18
    • 73149118287 scopus 로고    scopus 로고
    • Identification of a novel subset of human circulating memory CD4(+) T cells that produce both IL-17A and IL-4
    • Cosmi L, Maggi L, Santarlasci V, Capone M, Cardilicchia E, Frosali F et al (2010) Identification of a novel subset of human circulating memory CD4(+) T cells that produce both IL-17A and IL-4. J Allergy Clin Immunol 125(1): 222-230.
    • (2010) J Allergy Clin Immunol , vol.125 , Issue.1 , pp. 222-230
    • Cosmi, L.1    Maggi, L.2    Santarlasci, V.3    Capone, M.4    Cardilicchia, E.5    Frosali, F.6
  • 19
    • 0034193959 scopus 로고    scopus 로고
    • Requirement of endogenous stem cell factor and granulocyte-colony-stimulating factor for IL-17-mediated granulopoiesis
    • Schwarzenberger P, Huang W, Ye P, Oliver P, Manuel M, Zhang Z et al (2000) Requirement of endogenous stem cell factor and granulocyte-colony-stimulating factor for IL-17-mediated granulopoiesis. J Immunol 164: 4783-4789.
    • (2000) J Immunol , vol.164 , pp. 4783-4789
    • Schwarzenberger, P.1    Huang, W.2    Ye, P.3    Oliver, P.4    Manuel, M.5    Zhang, Z.6
  • 20
    • 42249084849 scopus 로고    scopus 로고
    • Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category
    • Luger D, Silver PB, Tang J, Cua D, Chen Z, Iwakura Y et al (2008) Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category. J Exp Med 205(4): 799-810.
    • (2008) J Exp Med , vol.205 , Issue.4 , pp. 799-810
    • Luger, D.1    Silver, P.B.2    Tang, J.3    Cua, D.4    Chen, Z.5    Iwakura, Y.6
  • 21
    • 46949104323 scopus 로고    scopus 로고
    • IL-12- and IL-23-modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition
    • Kroenke MA, Carlson TJ, Andjelkovic AV, Segal BM (2008) IL-12- and IL-23-modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition. J Exp Med 205(7): 1535-1541.
    • (2008) J Exp Med , vol.205 , Issue.7 , pp. 1535-1541
    • Kroenke, M.A.1    Carlson, T.J.2    Andjelkovic, A.V.3    Segal, B.M.4
  • 23
    • 60549086638 scopus 로고    scopus 로고
    • Th17 cells promote pancreatic inflammation but only induce diabetes efficiently in lymphopenic hosts after conversion into Th1 cells
    • Martin-Orozco N, Chung Y, Chang SH, Wang YH, Dong C (2009) Th17 cells promote pancreatic inflammation but only induce diabetes efficiently in lymphopenic hosts after conversion into Th1 cells. Eur J Immunol 39(1): 216-224.
    • (2009) Eur J Immunol , vol.39 , Issue.1 , pp. 216-224
    • Martin-Orozco, N.1    Chung, Y.2    Chang, S.H.3    Wang, Y.H.4    Dong, C.5
  • 24
    • 67349234068 scopus 로고    scopus 로고
    • IL-17 and Th17 cells in human inflammatory diseases
    • Miossec P (2009) IL-17 and Th17 cells in human inflammatory diseases. Microbes Infect 11(5): 625-630.
    • (2009) Microbes Infect , vol.11 , Issue.5 , pp. 625-630
    • Miossec, P.1
  • 25
    • 70449441060 scopus 로고    scopus 로고
    • Cytokines and cytokine profiles in human autoimmune diseases and animal models of autoimmunity
    • Kunz M, Ibrahim SM (2009) Cytokines and cytokine profiles in human autoimmune diseases and animal models of autoimmunity. Mediators Inflamm 979258, pp 20.
    • (2009) Mediators Inflamm 979258 , pp. 20
    • Kunz, M.1    Ibrahim, S.M.2
  • 26
    • 0034161692 scopus 로고    scopus 로고
    • High levels of IL-17 in rheumatoid arthritis patients: IL-15 triggers in vitro IL-17 production via cyclosporin A-sensitive mechanism
    • Ziolkowska M, Koc A, Luszczykiewicz G, Ksiezopolska-Pietrzak K, Klimczak E, Chwalinska-Sadowska H et al (2000) High levels of IL-17 in rheumatoid arthritis patients: IL-15 triggers in vitro IL-17 production via cyclosporin A-sensitive mechanism. J Immunol 164(5): 2832-2838.
    • (2000) J Immunol , vol.164 , Issue.5 , pp. 2832-2838
    • Ziolkowska, M.1    Koc, A.2    Luszczykiewicz, G.3    Ksiezopolska-Pietrzak, K.4    Klimczak, E.5    Chwalinska-Sadowska, H.6
  • 27
    • 33751521013 scopus 로고    scopus 로고
    • Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction
    • Sato K, Suematsu A, Okamoto K, Yamaguchi A, Morishita Y, Kadono Y et al (2006) Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction. J Exp Med 203: 2673-2682.
    • (2006) J Exp Med , vol.203 , pp. 2673-2682
    • Sato, K.1    Suematsu, A.2    Okamoto, K.3    Yamaguchi, A.4    Morishita, Y.5    Kadono, Y.6
  • 28
    • 33947617790 scopus 로고    scopus 로고
    • Effects on osteoclast and osteoblast activities in cultured mouse calvarial bones by synovial fluids from patients with a loose joint prosthesis and from osteoarthritis patients
    • Andersson MK, Lundberg P, Ohlin A, Perry MJ, Lie A, Stark A et al (2007) Effects on osteoclast and osteoblast activities in cultured mouse calvarial bones by synovial fluids from patients with a loose joint prosthesis and from osteoarthritis patients. Arthritis Res Ther 9: R18.
    • (2007) Arthritis Res Ther , vol.9
    • Andersson, M.K.1    Lundberg, P.2    Ohlin, A.3    Perry, M.J.4    Lie, A.5    Stark, A.6
  • 29
    • 33646349199 scopus 로고    scopus 로고
    • Synovial membrane cytokine expression is predictive of joint damage progression in rheumatoid arthritis: a two year prospective study (the DAMAGE study cohort)
    • Kirkham BW, Lassere MN, Edmonds JP, Juhasz KM, Bird PA, Lee CS et al (2006) Synovial membrane cytokine expression is predictive of joint damage progression in rheumatoid arthritis: a two year prospective study (the DAMAGE study cohort). Arthritis Rheum 54: 1122-1131.
    • (2006) Arthritis Rheum , vol.54 , pp. 1122-1131
    • Kirkham, B.W.1    Lassere, M.N.2    Edmonds, J.P.3    Juhasz, K.M.4    Bird, P.A.5    Lee, C.S.6
  • 30
    • 67651175878 scopus 로고    scopus 로고
    • Breaking old paradigms: Th17 cells in autoimmune arthritis
    • Peck A, Mellins ED (2009) Breaking old paradigms: Th17 cells in autoimmune arthritis. Clin Immunol 132(3): 295-304.
    • (2009) Clin Immunol , vol.132 , Issue.3 , pp. 295-304
    • Peck, A.1    Mellins, E.D.2
  • 31
    • 0035877257 scopus 로고    scopus 로고
    • Ubiquitous transgenic expression of the IL-23 subunit p19 induces multiorgan inflammation, runting, infertility, and premature death
    • Wiekowski MT, Leach MW, Evans EW, Sullivan L, Chen SC, Vassileva G et al (2001) Ubiquitous transgenic expression of the IL-23 subunit p19 induces multiorgan inflammation, runting, infertility, and premature death. J Immunol 166: 7563-7570.
    • (2001) J Immunol , vol.166 , pp. 7563-7570
    • Wiekowski, M.T.1    Leach, M.W.2    Evans, E.W.3    Sullivan, L.4    Chen, S.C.5    Vassileva, G.6
  • 32
    • 0346962972 scopus 로고    scopus 로고
    • Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation
    • Murphy CA, Langrish CL, Chen Y, Blumenschein W, McClanahan T, Kastelein RA et al (2003) Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation. J Exp Med 198: 1951-1957.
    • (2003) J Exp Med , vol.198 , pp. 1951-1957
    • Murphy, C.A.1    Langrish, C.L.2    Chen, Y.3    Blumenschein, W.4    McClanahan, T.5    Kastelein, R.A.6
  • 33
    • 39749089837 scopus 로고    scopus 로고
    • How signaling and gene transcription aberrations dictate the systemic lupus erythematosus T cell phenotype
    • Crispin JC, Kyttaris VC, Juang YT, Tsokos GC (2008) How signaling and gene transcription aberrations dictate the systemic lupus erythematosus T cell phenotype. Trends Immunol 29: 110-115.
    • (2008) Trends Immunol , vol.29 , pp. 110-115
    • Crispin, J.C.1    Kyttaris, V.C.2    Juang, Y.T.3    Tsokos, G.C.4
  • 35
    • 45249097325 scopus 로고    scopus 로고
    • Hyperproduction of IL-23 and IL-17 in patients with systemic lupus erythematosus: implications for Th17-mediated inflammation in auto-immunity
    • Wong CK, Lit LC, Tam LS, Li EK, Wong PT, Lam CW (2008) Hyperproduction of IL-23 and IL-17 in patients with systemic lupus erythematosus: implications for Th17-mediated inflammation in auto-immunity. Clin Immunol 127: 385-393.
    • (2008) Clin Immunol , vol.127 , pp. 385-393
    • Wong, C.K.1    Lit, L.C.2    Tam, L.S.3    Li, E.K.4    Wong, P.T.5    Lam, C.W.6
  • 36
    • 58849162766 scopus 로고    scopus 로고
    • Expanded double negative T cells in patients with systemic lupus erythematosus produce IL-17 and infiltrate the kidneys
    • Crispín JC, Oukka M, Bayliss G, Cohen RA, van Beek CA, Stillman IE et al (2008) Expanded double negative T cells in patients with systemic lupus erythematosus produce IL-17 and infiltrate the kidneys. J Immunol 181(12): 8761-8766.
    • (2008) J Immunol , vol.181 , Issue.12 , pp. 8761-8766
    • Crispín, J.C.1    Oukka, M.2    Bayliss, G.3    Cohen, R.A.4    van Beek, C.A.5    Stillman, I.E.6
  • 37
    • 70349238893 scopus 로고    scopus 로고
    • The role of IL-23/IL-17 axis in lupus nephritis
    • Zhang Z, Kyttaris VC, Tsokos GC (2009) The role of IL-23/IL-17 axis in lupus nephritis. J Immunol 183(5): 3160316-3160319.
    • (2009) J Immunol , vol.183 , Issue.5 , pp. 3160316-3160319
    • Zhang, Z.1    Kyttaris, V.C.2    Tsokos, G.C.3
  • 38
    • 33846238954 scopus 로고    scopus 로고
    • Psoriasis: a possible risk factor for development of coronary artery calcification
    • Ludwig RJ, Herzog C, Rostock A, Ochsendorf FR, Zollner TM, Thaci D et al (2007) Psoriasis: a possible risk factor for development of coronary artery calcification. Br J Dermatol 156(2): 271-276.
    • (2007) Br J Dermatol , vol.156 , Issue.2 , pp. 271-276
    • Ludwig, R.J.1    Herzog, C.2    Rostock, A.3    Ochsendorf, F.R.4    Zollner, T.M.5    Thaci, D.6
  • 39
    • 48849107322 scopus 로고    scopus 로고
    • Psoriasis, metabolic syndrome and its components
    • Ortonne JP (2008) Psoriasis, metabolic syndrome and its components. Ann Dermatol Venereol 135(Suppl 4): S235-S242.
    • (2008) Ann Dermatol Venereol , vol.135 , Issue.SUPPL. 4
    • Ortonne, J.P.1
  • 40
    • 33744936550 scopus 로고    scopus 로고
    • IL-23 is increased in dendritic cells in multiple sclerosis and downregulation of IL-23 by antisense oligos increases dendritic cell IL-10 production
    • Vaknin-Dembinsky A, Balashov K, Weiner HL (2006) IL-23 is increased in dendritic cells in multiple sclerosis and downregulation of IL-23 by antisense oligos increases dendritic cell IL-10 production. J Immunol 176(12): 7768-7774.
    • (2006) J Immunol , vol.176 , Issue.12 , pp. 7768-7774
    • Vaknin-Dembinsky, A.1    Balashov, K.2    Weiner, H.L.3
  • 41
    • 67651177581 scopus 로고    scopus 로고
    • Update on inflammation, neurodegeneration, and immunoregulation in multiple sclerosis: therapeutic implications
    • Bennett JL, Stüve O (2009) Update on inflammation, neurodegeneration, and immunoregulation in multiple sclerosis: therapeutic implications. Clin Neuropharmacol 32(3): 121-132.
    • (2009) Clin Neuropharmacol , vol.32 , Issue.3 , pp. 121-132
    • Bennett, J.L.1    Stüve, O.2
  • 42
    • 67650224449 scopus 로고    scopus 로고
    • Crohn's disease: Th1, Th17 or both? The change of a paradigm: new immunological and genetic insights implicate Th17 cells in the pathogenesis of Crohn's disease
    • Brand S (2009) Crohn's disease: Th1, Th17 or both? The change of a paradigm: new immunological and genetic insights implicate Th17 cells in the pathogenesis of Crohn's disease. Gut 58(8): 1152-1167.
    • (2009) Gut , vol.58 , Issue.8 , pp. 1152-1167
    • Brand, S.1
  • 43
    • 34648846718 scopus 로고    scopus 로고
    • Inflammatory responses induced by interleukin-17 family members in human colonic subepithelial myofibroblasts
    • Yagi Y, Andoh A, Inatomi O, Tsujikawa T, Fujiyama Y (2007) Inflammatory responses induced by interleukin-17 family members in human colonic subepithelial myofibroblasts. J Gastroenterol 42: 746-753.
    • (2007) J Gastroenterol , vol.42 , pp. 746-753
    • Yagi, Y.1    Andoh, A.2    Inatomi, O.3    Tsujikawa, T.4    Fujiyama, Y.5
  • 44
    • 41549160626 scopus 로고    scopus 로고
    • Interleukin-23 restrains regulatory T cell activity to drive T cell-dependent colitis
    • Izcue A, Hue S, Buonocore S, Arancibia-Cárcamo CV, Ahern PP, Iwakura Y et al (2008) Interleukin-23 restrains regulatory T cell activity to drive T cell-dependent colitis. Immunity 28(4): 559-570.
    • (2008) Immunity , vol.28 , Issue.4 , pp. 559-570
    • Izcue, A.1    Hue, S.2    Buonocore, S.3    Arancibia-Cárcamo, C.V.4    Ahern, P.P.5    Iwakura, Y.6
  • 45
    • 68849124464 scopus 로고    scopus 로고
    • The role of the novel Th17 cytokine IL-26 in intestinal inflammation
    • Dambacher J, Beigel F, Zitzmann K, De Toni EN, Göke B, Diepolder HM et al (2009) The role of the novel Th17 cytokine IL-26 in intestinal inflammation. Gut 58(9): 1207-1217.
    • (2009) Gut , vol.58 , Issue.9 , pp. 1207-1217
    • Dambacher, J.1    Beigel, F.2    Zitzmann, K.3    de Toni, E.N.4    Göke, B.5    Diepolder, H.M.6
  • 47
    • 68349130447 scopus 로고    scopus 로고
    • Regulatory T cells and asthma
    • Robinson DS (2009) Regulatory T cells and asthma. Clin Exp Allergy 39(9): 1314-1323.
    • (2009) Clin Exp Allergy , vol.39 , Issue.9 , pp. 1314-1323
    • Robinson, D.S.1
  • 48
    • 77956955243 scopus 로고    scopus 로고
    • Complement-mediated regulation of the IL-17A axis is a central genetic determinant of the severity of experimental allergic asthma
    • Lajoie S, Lewkowich IP, Suzuki Y, Clark JR, Sproles AA, Dienger K et al (2010) Complement-mediated regulation of the IL-17A axis is a central genetic determinant of the severity of experimental allergic asthma. Nat Immunol 11(10): 928-935.
    • (2010) Nat Immunol , vol.11 , Issue.10 , pp. 928-935
    • Lajoie, S.1    Lewkowich, I.P.2    Suzuki, Y.3    Clark, J.R.4    Sproles, A.A.5    Dienger, K.6
  • 49
    • 34648857789 scopus 로고    scopus 로고
    • Immunological tolerance and autoimmunity
    • Romagnani S (2006) Immunological tolerance and autoimmunity. Intern Emerg Med 1(3): 187-196.
    • (2006) Intern Emerg Med , vol.1 , Issue.3 , pp. 187-196
    • Romagnani, S.1


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