Suppression of cyclooxygenase-2 and inducible nitric oxide synthase expression by epimuqubilin A via IKK/IκB/NF-κB pathways in lipopolysaccharide-stimulated RAW 264.7 cells

Phytochemistry Letters

Volumn 4, Issue 4, 2011, Pages 426-431

  Park, Eun Jung ^a   Cheenpracha, Sarot ^a   Chang, Leng Chee ^a   Pezzuto, John M ^a  

^a UNIVERSITY OF HAWAII AT HILO   (United States)

Author keywords

Cyclooxygenase 2; Epimuqubilin A; Inducible nitric oxide synthase; Inhibitor B kinase; Norsesterterpene peroxide; RAW 264.7

Indexed keywords

1 [5 HYDROXY 2 (2 THIENYL) 4 QUINAZOLINYLAMINO] 3 METHYL 2,5 PYRROLEDIONE; 4 (2 AMINOETHYLAMINO) 1,8 DIMETHYLIMIDAZO[1,2 A]QUINOXALINE; 6 CHLORO 7 METHOXY 8 (2 METHYLNICOTINAMIDO) BETA CARBOLINE; 6 CHLORO 8 NICOTINAMIDO BETA CARBOLINE; ACETYLSALICYLIC ACID; ANTIINFLAMMATORY AGENT; ARSENIC TRIOXIDE; CYCLOOXYGENASE 2; EPIMUQUBILIN A; GENOMIC DNA; I KAPPA B; I KAPPA B KINASE; I KAPPA B KINASE INHIBITOR; IMD 0354; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; N [6 (4 CHLOROPHENOXY)HEXYL] N' CYANO N'' (4 PYRIDYL)GUANIDINE; NITRIC OXIDE; NORSESTERTERPENE PEROXIDE; SALICYLATE SODIUM; SC 514; SESTERTERPENE; SULINDAC; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CANCER PREVENTION; CONTROLLED STUDY; DNA BINDING; DOSE RESPONSE; DRUG EFFECT; DRUG ISOLATION; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENE EXPRESSION; LATRUNCULIA; MACROPHAGE; MARINE ENVIRONMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SPONGE (PORIFERA); WESTERN BLOTTING;

LATRUNCULIA;

EID: 81855197030     PISSN: 18743900     EISSN: 18767486     Source Type: Journal    
DOI: 10.1016/j.phytol.2011.07.009     Document Type: Article

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