Protein kinase D3 is a pivotal activator of pathological cardiac hypertrophy by selectively increasing the expression of hypertrophic transcription factors

Journal of Biological Chemistry

Volumn 286, Issue 47, 2011, Pages 40782-40791

  Li, Changlin ^a   Li, Jing ^a   Cai, Xiangyu ^a   Sun, Haili ^a   Jiao, Jinjin ^a   Bai, Ting ^a   Zhou, Xing Wang ^b   Chen, Xiongwen ^c   Gill, Donald L ^c   Tang, Xiang D ^a  

^a NANKAI UNIVERSITY   (China)

^b SUN YAT SEN UNIVERSITY   (China)

^c TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCINEURIN; CARDIAC GENES; CARDIAC HYPERTROPHY; DRUG TARGETS; GENE SILENCING; IN-VITRO; ISOPROTERENOL; MYOCYTE ENHANCER FACTOR 2; NUCLEAR ENTRY; NUCLEAR FACTOR OF ACTIVATED T-CELLS; NUCLEAR IMPORT; PROTEIN KINASE; SIGNALING CASCADES;

ENZYME INHIBITION; GENES; GENETIC ENGINEERING; HEART; PATHOLOGY; TRANSCRIPTION FACTORS;

TRANSCRIPTION;

CALCINEURIN; ISOPRENALINE; MYOCYTE ENHANCER FACTOR 2; PROTEIN KINASE; PROTEIN KINASE D1; PROTEIN KINASE D3; TRANSCRIPTION FACTOR GATA 4; TRANSCRIPTION FACTOR NFAT; TRANSCRIPTION FACTOR NFATC1; TRANSCRIPTION FACTOR NFATC3; TRANSCRIPTION FACTOR NFATC4; TRANSCRIPTION FACTOR NKX2.5; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; DISEASE MODEL; ENZYME INDUCTION; GENE SILENCING; HEART VENTRICLE HYPERTROPHY; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN TRANSPORT; RAT; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; ANIMALS, NEWBORN; CARDIOMEGALY; ISOPROTERENOL; MYOCYTES, CARDIAC; PROTEIN KINASE C; PROTEIN KINASES; RATS; RATS, SPRAGUE-DAWLEY; TRANSCRIPTION FACTORS; TRANSCRIPTIONAL ACTIVATION; UP-REGULATION;

EID: 81755181690     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.263046     Document Type: Article

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