The δA isoform of calmodulin kinase II mediates pathological cardiac hypertrophy by interfering with the HDAC4-MEF2 signaling pathway

Biochemical and Biophysical Research Communications

Volumn 409, Issue 1, 2011, Pages 125-130

  Li, Changlin ^a   Cai, Xiangyu ^a   Sun, Haili ^a   Bai, Ting ^a   Zheng, Xilong ^a,d   Zhou, Xing Wang ^b   Chen, Xiongwen ^c   Gill, Donald L ^c   Li, Jing ^a   Tang, Xiang D ^a,d  

^a NANKAI UNIVERSITY   (China)

^b SUN YAT SEN UNIVERSITY   (China)

^c TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d MOE Key Laboratory of Bioactive Materials   (China)

Author keywords

Myosin heavy chain ( MHC); Atrial natriuretic factor (ANF); Cardiac hypertrophy; Histone deacetylase (HDAC); Nuclear factor of activated T cell (NFAT)

Indexed keywords

ATRIAL NATRIURETIC FACTOR; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CALMODULIN KINASE II DELTAA; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HISTONE DEACETYLASE 4; ISOENZYME; MYOCYTE ENHANCER FACTOR 2; MYOSIN HEAVY CHAIN BETA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL ENLARGEMENT; CONTROLLED STUDY; GENE ACTIVATION; GENE SILENCING; HEART VENTRICLE HYPERTROPHY; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; SARCOMERE; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CARDIOMEGALY; GENE SILENCING; HISTONE DEACETYLASES; ISOENZYMES; MADS DOMAIN PROTEINS; MYOGENIC REGULATORY FACTORS; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 79956217854     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.04.128     Document Type: Article

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