Impact of pyrrolidine dithiocarbamate and interleukin-6 on mammalian target of rapamycin complex 1 regulation and global protein translation

Journal of Pharmacology and Experimental Therapeutics

Volumn 339, Issue 3, 2011, Pages 905-913

  Song, Shaoming ^a   Abdelmohsen, Kotb ^a   Zhang, Yongqing ^a   Becker, Kevin G ^a   Gorospe, Myriam ^a   Bernier, Michel ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BAG3 PROTEIN; DEDD2 PROTEIN; DNA DAMAGE INDUCIBLE TRANSCRIPT 4 PROTEIN; GENE PRODUCT; GLYCOGEN SYNTHASE KINASE 3BETA; HEAT SHOCK TRANSCRIPTION FACTOR 1; HSPA1A PROTEIN; IER3 PROTEIN; INITIATION FACTOR 4E BINDING PROTEIN 1; INTERLEUKIN 6; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; PROTEIN KINASE B; PROTEIN MCL 1; PROTEIN S 16; PYRROLIDINE DITHIOCARBAMATE; RADIATION INDUCIBLE IMMEDIATE EARLY PROTEIN; REGULATOR PROTEIN; RIBOSOMAL PROTEIN L14; RIBOSOMAL PROTEIN L23; RIBOSOMAL PROTEIN L27; RIBOSOMAL PROTEIN LARGE P1; RIBOSOMAL PROTEIN S15A; RIBOSOMAL PROTEIN S28; RIBOSOMAL PROTEIN S3; RIBOSOME PROTEIN; S6K1 PROTEIN; SMALL INTERFERING RNA; STAT3 PROTEIN; TRANSCRIPTION FACTOR JUND; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; BAG3 GENE; CONTROLLED STUDY; DEDD2 GENE; DNA DAMAGE INDUCIBLE TRANSCRIPT 4 GENE; DNA MICROARRAY; DOWN REGULATION; GENE; GENE ACTIVATION; GENE EXPRESSION PROFILING; GENETIC ASSOCIATION; HEAT SHOCK TRANSCRIPTION FACTOR 1 GENE; HSPA1A GENE; HUMAN; HUMAN CELL; IER3 GENE; JUND GENE; MCL1 GENE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; RIBOSOMAL PROTEIN L14 GENE; RIBOSOMAL PROTEIN L23 GENE; RIBOSOMAL PROTEIN L27 GENE; RIBOSOMAL PROTEIN LARGE P1 GENE; RIBOSOMAL PROTEIN S15A GENE; RIBOSOMAL PROTEIN S16 GENE; RIBOSOMAL PROTEIN S28 GENE; RIBOSOMAL PROTEIN S3 GENE; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; TRANSLATION REGULATION; UPREGULATION; WESTERN BLOTTING;

ANTIOXIDANTS; CYTOKINES; DOWN-REGULATION; GENE EXPRESSION PROFILING; HEP G2 CELLS; HUMANS; INTERLEUKIN-6; NF-KAPPA B; PROTEIN BIOSYNTHESIS; PROTEINS; PYRROLIDINES; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; THIOCARBAMATES; TRANSCRIPTION FACTORS; TRANSCRIPTIONAL ACTIVATION; UP-REGULATION;

EID: 81555205600     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.111.185678     Document Type: Article

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