메뉴 건너뛰기




Volumn 109, Issue 1, 2012, Pages 213-224

A multivariate model of ErbB network composition predicts ovarian cancer cell response to canertinib

Author keywords

Epithelial ovarian cancer; ErbB network; Partial least squares regression; Systems biology

Indexed keywords

AUTOCRINE LOOP; CELL LINES; CI-1033; CLINICAL PROBLEMS; COMPLEX DISEASE; FULL MODEL; MODEL ANALYSIS; MULTIVARIATE FUNCTION; MULTIVARIATE MODELS; NETWORK COMPOSITION; OPTIMAL TREATMENT; OVARIAN CANCER CELLS; OVARIAN CANCERS; PARTIAL LEAST SQUARES REGRESSION; RECEPTOR LEVELS; SYSTEMS BIOLOGY; TRAINING SETS;

EID: 81455158899     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.23297     Document Type: Article
Times cited : (16)

References (46)
  • 2
    • 67649440886 scopus 로고    scopus 로고
    • The biology of ovarian cancer: New opportunities for translation
    • Bast RC Jr, Hennessy B, Mills GB. 2009. The biology of ovarian cancer: New opportunities for translation. Nat Rev Cancer 9(6): 415-428.
    • (2009) Nat Rev Cancer , vol.9 , Issue.6 , pp. 415-428
    • Bast Jr., R.C.1    Hennessy, B.2    Mills, G.B.3
  • 3
    • 0031706616 scopus 로고    scopus 로고
    • Coexpression of the HER-2 gene product, p185HER-2, and epidermal growth factor receptor, p170EGF-R, on epithelial ovarian cancers and normal tissues
    • Bast RC Jr, Pusztai L, Kerns BJ, MacDonald JA, Jordan P, Daly L, Boyer CM, Mendelsohn J, Berchuck A. 1998. Coexpression of the HER-2 gene product, p185HER-2, and epidermal growth factor receptor, p170EGF-R, on epithelial ovarian cancers and normal tissues. Hybridoma 17(4): 313-321.
    • (1998) Hybridoma , vol.17 , Issue.4 , pp. 313-321
    • Bast Jr., R.C.1    Pusztai, L.2    Kerns, B.J.3    MacDonald, J.A.4    Jordan, P.5    Daly, L.6    Boyer, C.M.7    Mendelsohn, J.8    Berchuck, A.9
  • 6
    • 0020089191 scopus 로고
    • Cross-validatory choice of the number of components from a principal component analysis
    • Eastment HT, Krzanowski WJ. 1982. Cross-validatory choice of the number of components from a principal component analysis. Technometrics 24(1): 73-77.
    • (1982) Technometrics , vol.24 , Issue.1 , pp. 73-77
    • Eastment, H.T.1    Krzanowski, W.J.2
  • 7
    • 67349095676 scopus 로고    scopus 로고
    • Associations between ERBB2 amplification and progression-free survival and overall survival in advanced stage, suboptimally-resected epithelial ovarian cancers: A Gynecologic Oncology Group Study
    • Farley J, Fuchiuji S, Darcy KM, Tian C, Hoskins WJ, McGuire WP, Hanjani P, Warshal D, Greer BE, Belinson J, Birrer MJ. 2009. Associations between ERBB2 amplification and progression-free survival and overall survival in advanced stage, suboptimally-resected epithelial ovarian cancers: A Gynecologic Oncology Group Study. Gynecol Oncol 113(3): 341-347.
    • (2009) Gynecol Oncol , vol.113 , Issue.3 , pp. 341-347
    • Farley, J.1    Fuchiuji, S.2    Darcy, K.M.3    Tian, C.4    Hoskins, W.J.5    McGuire, W.P.6    Hanjani, P.7    Warshal, D.8    Greer, B.E.9    Belinson, J.10    Birrer, M.J.11
  • 9
    • 11144325691 scopus 로고
    • Partial least-squares regression: A tutorial
    • Geladi P, Kowalski BR. 1986. Partial least-squares regression: A tutorial. Anal Chim Acta 185: 1-17.
    • (1986) Anal Chim Acta , vol.185 , pp. 1-17
    • Geladi, P.1    Kowalski, B.R.2
  • 11
    • 28944439741 scopus 로고    scopus 로고
    • Efficacy and safety of erlotinib HCl, an epidermal growth factor receptor (HER1/EGFR) tyrosine kinase inhibitor, in patients with advanced ovarian carcinoma: Results from a phase II multicenter study
    • Gordon AN, Finkler N, Edwards RP, Garcia AA, Crozier M, Irwin DH, Barrett E. 2005. Efficacy and safety of erlotinib HCl, an epidermal growth factor receptor (HER1/EGFR) tyrosine kinase inhibitor, in patients with advanced ovarian carcinoma: Results from a phase II multicenter study. Int J Gynecol Cancer 15(5): 785-792.
    • (2005) Int J Gynecol Cancer , vol.15 , Issue.5 , pp. 785-792
    • Gordon, A.N.1    Finkler, N.2    Edwards, R.P.3    Garcia, A.A.4    Crozier, M.5    Irwin, D.H.6    Barrett, E.7
  • 14
    • 68949213744 scopus 로고    scopus 로고
    • Predictive value of EGFR and HER2 overexpression in advanced non-small-cell lung cancer
    • Hirsch FR, Varella-Garcia M, Cappuzzo F. 2009. Predictive value of EGFR and HER2 overexpression in advanced non-small-cell lung cancer. Oncogene 28 (Suppl 1): S32-S37.
    • (2009) Oncogene , vol.28 , Issue.SUPPL. 1
    • Hirsch, F.R.1    Varella-Garcia, M.2    Cappuzzo, F.3
  • 16
    • 79960420158 scopus 로고    scopus 로고
    • Targeted therapies in epithelial ovarian cancer: Molecular mechanisms of action
    • Itamochi H. 2010. Targeted therapies in epithelial ovarian cancer: Molecular mechanisms of action. World J Biol Chem 1(7): 209-220.
    • (2010) World J Biol Chem , vol.1 , Issue.7 , pp. 209-220
    • Itamochi, H.1
  • 17
    • 28844441230 scopus 로고    scopus 로고
    • A systems model of signaling identifies a molecular basis set for cytokine-induced apoptosis
    • Janes KA, Albeck JG, Gaudet S, Sorger PK, Lauffenburger DA, Yaffe MB. 2005. A systems model of signaling identifies a molecular basis set for cytokine-induced apoptosis. Science 310(5754): 1646-1653.
    • (2005) Science , vol.310 , pp. 1646-1653
    • Janes, K.A.1    Albeck, J.G.2    Gaudet, S.3    Sorger, P.K.4    Lauffenburger, D.A.5    Yaffe, M.B.6
  • 18
    • 4544381664 scopus 로고    scopus 로고
    • Cue-signal-response analysis of TNF-induced apoptosis by partial least squares regression of dynamic multivariate data
    • Janes KA, Kelly JR, Gaudet S, Albeck JG, Sorger PK, Lauffenburger DA. 2004. Cue-signal-response analysis of TNF-induced apoptosis by partial least squares regression of dynamic multivariate data. J Comput Biol 11(4): 544-561.
    • (2004) J Comput Biol , vol.11 , Issue.4 , pp. 544-561
    • Janes, K.A.1    Kelly, J.R.2    Gaudet, S.3    Albeck, J.G.4    Sorger, P.K.5    Lauffenburger, D.A.6
  • 21
    • 70350228452 scopus 로고    scopus 로고
    • RAS mutations affect tumor necrosis factor-induced apoptosis in colon carcinoma cells via ERK-modulatory negative and positive feedback circuits along with non-ERK pathway effects
    • Kreeger PK, Mandhana R, Alford SK, Haigis KM, Lauffenburger DA. 2009. RAS mutations affect tumor necrosis factor-induced apoptosis in colon carcinoma cells via ERK-modulatory negative and positive feedback circuits along with non-ERK pathway effects. Cancer Res 69(20): 8191-8199.
    • (2009) Cancer Res , vol.69 , Issue.20 , pp. 8191-8199
    • Kreeger, P.K.1    Mandhana, R.2    Alford, S.K.3    Haigis, K.M.4    Lauffenburger, D.A.5
  • 22
    • 77951718940 scopus 로고    scopus 로고
    • Integration of multiple signaling pathway activities resolves K-RAS/N-RAS mutation paradox in colon epithelial cell response to inflammatory cytokine stimulation
    • Kreeger PK, Wang Y, Haigis KM, Lauffenburger DA. 2010. Integration of multiple signaling pathway activities resolves K-RAS/N-RAS mutation paradox in colon epithelial cell response to inflammatory cytokine stimulation. Integr Biol (Camb) 2(4): 202-208.
    • (2010) Integr Biol (Camb) , vol.2 , Issue.4 , pp. 202-208
    • Kreeger, P.K.1    Wang, Y.2    Haigis, K.M.3    Lauffenburger, D.A.4
  • 23
    • 44249090908 scopus 로고    scopus 로고
    • Multipathway model enables prediction of kinase inhibitor cross-talk effects on migration of Her2-overexpressing mammary epithelial cells
    • Kumar N, Afeyan R, Kim HD, Lauffenburger DA. 2008. Multipathway model enables prediction of kinase inhibitor cross-talk effects on migration of Her2-overexpressing mammary epithelial cells. Mol Pharmacol 73(6): 1668-1678.
    • (2008) Mol Pharmacol , vol.73 , Issue.6 , pp. 1668-1678
    • Kumar, N.1    Afeyan, R.2    Kim, H.D.3    Lauffenburger, D.A.4
  • 24
    • 41949100690 scopus 로고    scopus 로고
    • Clinical implications of the ErbB/epidermal growth factor (EGF) receptor family and its ligands in ovarian cancer
    • Lafky JM, Wilken JA, Baron AT, Maihle NJ. 2008. Clinical implications of the ErbB/epidermal growth factor (EGF) receptor family and its ligands in ovarian cancer. Biochim Biophys Acta 1785(2): 232-265.
    • (2008) Biochim Biophys Acta , vol.1785 , Issue.2 , pp. 232-265
    • Lafky, J.M.1    Wilken, J.A.2    Baron, A.T.3    Maihle, N.J.4
  • 25
    • 79953102845 scopus 로고    scopus 로고
    • In vivo systems analysis identifies spatial and temporal aspects of the modulation of TNF-alpha-induced apoptosis and proliferation by MAPKs
    • Lau KS, Juchheim AM, Cavaliere KR, Philips SR, Lauffenburger DA, Haigis KM. 2011. In vivo systems analysis identifies spatial and temporal aspects of the modulation of TNF-alpha-induced apoptosis and proliferation by MAPKs. Sci Signal 4(165): ra16.
    • (2011) Sci Signal , vol.4 , Issue.165
    • Lau, K.S.1    Juchheim, A.M.2    Cavaliere, K.R.3    Philips, S.R.4    Lauffenburger, D.A.5    Haigis, K.M.6
  • 26
    • 34547623194 scopus 로고    scopus 로고
    • Common effector processing mediates cell-specific responses to stimuli
    • Miller-Jensen K, Janes KA, Brugge JS, Lauffenburger DA. 2007. Common effector processing mediates cell-specific responses to stimuli. Nature 448(7153): 604-608.
    • (2007) Nature , vol.448 , pp. 604-608
    • Miller-Jensen, K.1    Janes, K.A.2    Brugge, J.S.3    Lauffenburger, D.A.4
  • 29
    • 0030905266 scopus 로고    scopus 로고
    • Expression of epidermal growth factor-related proteins and epidermal growth factor receptor in common epithelial ovarian tumors
    • Niikura H, Sasano H, Sato S, Yajima A. 1997. Expression of epidermal growth factor-related proteins and epidermal growth factor receptor in common epithelial ovarian tumors. Int J Gynecol Pathol 16(1): 60-68.
    • (1997) Int J Gynecol Pathol , vol.16 , Issue.1 , pp. 60-68
    • Niikura, H.1    Sasano, H.2    Sato, S.3    Yajima, A.4
  • 37
    • 41349105997 scopus 로고    scopus 로고
    • Histologic subtypes of ovarian carcinoma: An overview
    • Soslow RA. 2008. Histologic subtypes of ovarian carcinoma: An overview. Int J Gynecol Pathol 27(2): 161-174.
    • (2008) Int J Gynecol Pathol , vol.27 , Issue.2 , pp. 161-174
    • Soslow, R.A.1
  • 38
    • 0026558357 scopus 로고
    • Transforming growth factor-alpha acts as an autocrine growth factor in ovarian carcinoma cell lines
    • Stromberg K, Collins TJT, Gordon AW, Jackson CL, Johnson GR. 1992. Transforming growth factor-alpha acts as an autocrine growth factor in ovarian carcinoma cell lines. Cancer Res 52(2): 341-347.
    • (1992) Cancer Res , vol.52 , Issue.2 , pp. 341-347
    • Stromberg, K.1    Collins, T.J.T.2    Gordon, A.W.3    Jackson, C.L.4    Johnson, G.R.5
  • 39
    • 29144434036 scopus 로고    scopus 로고
    • 2C4, a monoclonal antibody against HER2, disrupts the HER kinase signaling pathway and inhibits ovarian carcinoma cell growth
    • Takai N, Jain A, Kawamata N, Popoviciu LM, Said JW, Whittaker S, Miyakawa I, Agus DB, Koeffler HP. 2005. 2C4, a monoclonal antibody against HER2, disrupts the HER kinase signaling pathway and inhibits ovarian carcinoma cell growth. Cancer 104(12): 2701-2708.
    • (2005) Cancer , vol.104 , Issue.12 , pp. 2701-2708
    • Takai, N.1    Jain, A.2    Kawamata, N.3    Popoviciu, L.M.4    Said, J.W.5    Whittaker, S.6    Miyakawa, I.7    Agus, D.B.8    Koeffler, H.P.9
  • 41
    • 77958502507 scopus 로고    scopus 로고
    • Traditional molecular markers and response to adjuvant endocrine or trastuzumab-based therapies
    • Viale G, Ghioni M, Mastropasqua MG. 2010. Traditional molecular markers and response to adjuvant endocrine or trastuzumab-based therapies. Curr Opin Oncol 22(6): 541-546.
    • (2010) Curr Opin Oncol , vol.22 , Issue.6 , pp. 541-546
    • Viale, G.1    Ghioni, M.2    Mastropasqua, M.G.3
  • 42
    • 0032713438 scopus 로고    scopus 로고
    • The outcome of heregulin-induced activation of ovarian cancer cells depends on the relative levels of HER-2 and HER-3 expression
    • Xu F, Yu Y, Le XF Boyer C, Mills GB, Bast RC Jr. 1999. The outcome of heregulin-induced activation of ovarian cancer cells depends on the relative levels of HER-2 and HER-3 expression. Clin Cancer Res 5(11): 3653-3660.
    • (1999) Clin Cancer Res , vol.5 , Issue.11 , pp. 3653-3660
    • Xu, F.1    Yu, Y.2    Le, X.F.3    Boyer, C.4    Mills, G.B.5    Bast Jr., R.C.6
  • 43
    • 19944391895 scopus 로고    scopus 로고
    • Clinical significance of heparin-binding epidermal growth factor-like growth factor in peritoneal fluid of ovarian cancer
    • Yagi H, Miyamoto S, Tanaka Y, Sonoda K, Kobayashi H, Kishikawa T, Iwamoto R, Mekada E, Nakano H. 2005. Clinical significance of heparin-binding epidermal growth factor-like growth factor in peritoneal fluid of ovarian cancer. Br J Cancer 92(9): 1737-1745.
    • (2005) Br J Cancer , vol.92 , Issue.9 , pp. 1737-1745
    • Yagi, H.1    Miyamoto, S.2    Tanaka, Y.3    Sonoda, K.4    Kobayashi, H.5    Kishikawa, T.6    Iwamoto, R.7    Mekada, E.8    Nakano, H.9
  • 44
    • 60749137451 scopus 로고    scopus 로고
    • Beyond chemotherapy: Targeted therapies in ovarian cancer
    • Yap TA, Carden CP, Kaye SB. 2009. Beyond chemotherapy: Targeted therapies in ovarian cancer. Nat Rev Cancer 9(3): 167-181.
    • (2009) Nat Rev Cancer , vol.9 , Issue.3 , pp. 167-181
    • Yap, T.A.1    Carden, C.P.2    Kaye, S.B.3
  • 45
    • 0035256698 scopus 로고    scopus 로고
    • Untangling the ErbB signalling network
    • Yarden Y, Sliwkowski MX. 2001. Untangling the ErbB signalling network. Nat Rev Mol Cell Biol 2(2): 127-137.
    • (2001) Nat Rev Mol Cell Biol , vol.2 , Issue.2 , pp. 127-137
    • Yarden, Y.1    Sliwkowski, M.X.2
  • 46
    • 77957336226 scopus 로고    scopus 로고
    • Targeting the EGF receptor for ovarian cancer therapy
    • Zeineldin R, Muller CY, Stack MS, Hudson LG. 2010. Targeting the EGF receptor for ovarian cancer therapy. J Oncol 2010: 414676.
    • (2010) J Oncol , vol.2010 , pp. 414676
    • Zeineldin, R.1    Muller, C.Y.2    Stack, M.S.3    Hudson, L.G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.