-
2
-
-
0028955388
-
Epidermal growth factor-related peptides and their receptors in human malignancies
-
Salomon DS, Brandt R, Ciardiello F, Normanno N. Epidermal growth factor-related peptides and their receptors in human malignancies. Crit Rev Oncol Hematol 1995;19:183-232.
-
(1995)
Crit Rev Oncol Hematol
, vol.19
, pp. 183-232
-
-
Salomon, D.S.1
Brandt, R.2
Ciardiello, F.3
Normanno, N.4
-
3
-
-
1642421130
-
Target-based agents against ErbB receptors and their ligands: A novel approach to cancer treatment
-
Normanno N, Bianco C, De Luca A, Maiello MR, Salomon DS. Target-based agents against ErbB receptors and their ligands: a novel approach to cancer treatment. Endocr Relat Cancer 2003;10:1-21.
-
(2003)
Endocr Relat Cancer
, vol.10
, pp. 1-21
-
-
Normanno, N.1
Bianco, C.2
De Luca, A.3
Maiello, M.R.4
Salomon, D.S.5
-
4
-
-
0026517954
-
Significance of epidermal growth factor receptor in advanced ovarian cancer
-
Scambia G, Benedetti Panici P, Battaglia F, et al. Significance of epidermal growth factor receptor in advanced ovarian cancer. J Clin Oncol 1992;10:529-35.
-
(1992)
J Clin Oncol
, vol.10
, pp. 529-535
-
-
Scambia, G.1
Benedetti Panici, P.2
Battaglia, F.3
-
5
-
-
0036834993
-
Transforming growth factor alpha, amphiregulin and cripto-I are frequently expressed in advanced human ovarian carcinomas
-
D'Antonio A, Losito S, Pignata S, et al. Transforming growth factor alpha, amphiregulin and cripto-I are frequently expressed in advanced human ovarian carcinomas. Int J Oncol 2002;21:941-8.
-
(2002)
Int J Oncol
, vol.21
, pp. 941-948
-
-
D'Antonio, A.1
Losito, S.2
Pignata, S.3
-
6
-
-
0026005833
-
Evidence for the involvement of transforming growth factor alpha and epidermal growth factor receptor autocrine growth mechanism in primary human ovarian cancers in vitro
-
Morishige K, Kurachi H, Amemiya K, et al. Evidence for the involvement of transforming growth factor alpha and epidermal growth factor receptor autocrine growth mechanism in primary human ovarian cancers in vitro. Cancer Res 1991;51:5322-8.
-
(1991)
Cancer Res
, vol.51
, pp. 5322-5328
-
-
Morishige, K.1
Kurachi, H.2
Amemiya, K.3
-
7
-
-
0026001496
-
Synergistic effect of tumor necrosis factor-alpha- and diphtheria toxin-mediated cytotoxicity in sensitive and resistant human ovarian tumor cell lines
-
Morimoto H, Safrit JT, Bonavida B. Synergistic effect of tumor necrosis factor-alpha- and diphtheria toxin-mediated cytotoxicity in sensitive and resistant human ovarian tumor cell lines. J Immunol 1991;147:2609-16.
-
(1991)
J Immunol
, vol.147
, pp. 2609-2616
-
-
Morimoto, H.1
Safrit, J.T.2
Bonavida, B.3
-
8
-
-
0028284810
-
Heparin-binding EGF-like growth factor, which acts as the diphtheria toxin receptor, forms a complex with membrane protein DRAP27/CD9, which up-regulates functional receptors and diphtheria toxin sensitivity
-
Iwamoto R, Higashiyama S, Mitamura T, et al. Heparin-binding EGF-like growth factor, which acts as the diphtheria toxin receptor, forms a complex with membrane protein DRAP27/CD9, which up-regulates functional receptors and diphtheria toxin sensitivity. EMBO J 1994;13:2322-30.
-
(1994)
EMBO J
, vol.13
, pp. 2322-2330
-
-
Iwamoto, R.1
Higashiyama, S.2
Mitamura, T.3
-
9
-
-
0025904265
-
A heparin-binding growth factor secreted by macrophage-like cells that is related to EGF
-
Higashiyama S, Abraham JA, Miller J, Fiddes JC, Klagsbrun M. A heparin-binding growth factor secreted by macrophage-like cells that is related to EGF. Science (Wash DC) 1991;251:936-9.
-
(1991)
Science (Wash DC)
, vol.251
, pp. 936-939
-
-
Higashiyama, S.1
Abraham, J.A.2
Miller, J.3
Fiddes, J.C.4
Klagsbrun, M.5
-
10
-
-
0029118420
-
Phorbol ester induces the rapid processing of cell surface heparin-binding EGF-like growth factor: Conversion from juxtacrine to paracrine growth factor activity
-
Goishi K, Higashiyama S, Klagsbrun M, et al. Phorbol ester induces the rapid processing of cell surface heparin-binding EGF-like growth factor: conversion from juxtacrine to paracrine growth factor activity. Mol Biol Cell 1995;6:967-80.
-
(1995)
Mol Biol Cell
, vol.6
, pp. 967-980
-
-
Goishi, K.1
Higashiyama, S.2
Klagsbrun, M.3
-
12
-
-
10744230888
-
Mice with defects in HB-EGF ectodomain shedding show severe developmental abnormalities
-
Yamazaki S, Iwamoto R, Saeki K, et al. Mice with defects in HB-EGF ectodomain shedding show severe developmental abnormalities. J Cell Biol 2003;163:469-75.
-
(2003)
J Cell Biol
, vol.163
, pp. 469-475
-
-
Yamazaki, S.1
Iwamoto, R.2
Saeki, K.3
-
13
-
-
0037593847
-
The stress- and inflammatory cytokine-induced ectodomain shedding of heparin-binding epidermal growth factor-like growth factor is mediated by p38 MAPK, distinct from the 12-O-tetra-decanoylphorbol-13-acetate- and lysophosphatidic acid-induced signaling cascades
-
Takenobu H, Yamazaki A, Hirata M, Umata T, Mekada E. The stress- and inflammatory cytokine-induced ectodomain shedding of heparin-binding epidermal growth factor-like growth factor is mediated by p38 MAPK, distinct from the 12-O-tetra-decanoylphorbol-13-acetate- and lysophosphatidic acid-induced signaling cascades. J Biol Chem 2003;278:17255-62.
-
(2003)
J Biol Chem
, vol.278
, pp. 17255-17262
-
-
Takenobu, H.1
Yamazaki, A.2
Hirata, M.3
Umata, T.4
Mekada, E.5
-
14
-
-
0033599039
-
EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of pro-HB-EGF
-
Prenzel N, Zwick E, Daub H, et al. EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of pro-HB-EGF. Nature (Lond) 1999;402:884-8.
-
(1999)
Nature (Lond)
, vol.402
, pp. 884-888
-
-
Prenzel, N.1
Zwick, E.2
Daub, H.3
-
15
-
-
0034811076
-
Identification of serum factor inducing ectodomain shedding of pro-HB-EGF and studies of noncleavable mutants of pro-HB-EGF
-
Hirata M, Umata T, Takahashi T, et al. Identification of serum factor inducing ectodomain shedding of pro-HB-EGF and studies of noncleavable mutants of pro-HB-EGF. Biochem Biophys Res Commun 2001;283:915-22.
-
(2001)
Biochem Biophys Res Commun
, vol.283
, pp. 915-922
-
-
Hirata, M.1
Umata, T.2
Takahashi, T.3
-
16
-
-
0023860289
-
A putative new growth factor in ascitic fluid from ovarian cancer patients: Identification, characterization, and mechanism of action
-
Mills GB, May C, McGill M, Roifman CM, Mellors A. A putative new growth factor in ascitic fluid from ovarian cancer patients: identification, characterization, and mechanism of action. Cancer Res 1988;48:1066-71.
-
(1988)
Cancer Res
, vol.48
, pp. 1066-1071
-
-
Mills, G.B.1
May, C.2
McGill, M.3
Roifman, C.M.4
Mellors, A.5
-
17
-
-
0031747415
-
Malignant effusions contain lysophosphatidic acid (LPA)-like activity
-
Westermann AM, Havik E, Postma FR, et al. Malignant effusions contain lysophosphatidic acid (LPA)-like activity. Ann Oncol 1998;9:437-42.
-
(1998)
Ann Oncol
, vol.9
, pp. 437-442
-
-
Westermann, A.M.1
Havik, E.2
Postma, F.R.3
-
18
-
-
0028871499
-
Characterization of an ovarian cancer activating factor in ascites from ovarian cancer patients
-
Xu Y, Gaudette DC, Boynton JD, et al. Characterization of an ovarian cancer activating factor in ascites from ovarian cancer patients. Clin Cancer Res 1995;1:1223-32.
-
(1995)
Clin Cancer Res
, vol.1
, pp. 1223-1232
-
-
Xu, Y.1
Gaudette, D.C.2
Boynton, J.D.3
-
20
-
-
0242339246
-
Lysophosphatidic acid is a bioactive mediator in ovarian cancer
-
Fang X, Schummer M, Mao M, et al. Lysophosphatidic acid is a bioactive mediator in ovarian cancer. Biochim Biophys Acta 2002;1582:257-64.
-
(2002)
Biochim Biophys Acta
, vol.1582
, pp. 257-264
-
-
Fang, X.1
Schummer, M.2
Mao, M.3
-
21
-
-
0034062462
-
Mechanisms of lysolipid phosphate effects on cellular survival and proliferation
-
Goetzl EJ, Lee H, Dolezalova H, et al. Mechanisms of lysolipid phosphate effects on cellular survival and proliferation. Ann N Y Acad Sci 2000;905:177-87.
-
(2000)
Ann N Y Acad Sci
, vol.905
, pp. 177-187
-
-
Goetzl, E.J.1
Lee, H.2
Dolezalova, H.3
-
22
-
-
0032569235
-
Lysophosphatidic acid as a potential biomarker for ovarian and other gynecologic cancers
-
Xu Y, Shen Z, Wiper DW, et al. Lysophosphatidic acid as a potential biomarker for ovarian and other gynecologic cancers. JAMA 1998;280:719-23.
-
(1998)
JAMA
, vol.280
, pp. 719-723
-
-
Xu, Y.1
Shen, Z.2
Wiper, D.W.3
-
23
-
-
0038581051
-
TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cells
-
Gschwind A, Hart S, Fischer OM, Ullrich A. TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cells. EMBO J 2003;22:2411-21.
-
(2003)
EMBO J
, vol.22
, pp. 2411-2421
-
-
Gschwind, A.1
Hart, S.2
Fischer, O.M.3
Ullrich, A.4
-
24
-
-
0015919833
-
Diphtheria toxin and related proteins. I. Isolation and properties of mutant proteins serologically related to diphtheria toxin
-
Uchida T, Pappenheimer AM Jr, Greany R. Diphtheria toxin and related proteins. I. Isolation and properties of mutant proteins serologically related to diphtheria toxin. J Biol Chem 1973;248:3838-44.
-
(1973)
J Biol Chem
, vol.248
, pp. 3838-3844
-
-
Uchida, T.1
Pappenheimer Jr., A.M.2
Greany, R.3
-
26
-
-
0037021437
-
Small interfering RNA and gene silencing in transgenic mice and rats
-
Hasuwa H, Kaseda K, Einarsdottir T, Okabe M. Small interfering RNA and gene silencing in transgenic mice and rats. FEBS Lett 2002;532:227-30.
-
(2002)
FEBS Lett
, vol.532
, pp. 227-230
-
-
Hasuwa, H.1
Kaseda, K.2
Einarsdottir, T.3
Okabe, M.4
-
27
-
-
0028954797
-
Synergistic roles for receptor occupancy and aggregation in integrin transmembrane function
-
Miyamoto S, Akiyama SK, Yamada KM. Synergistic roles for receptor occupancy and aggregation in integrin transmembrane function. Science (Wash DC) 1995;267:883-5.
-
(1995)
Science (Wash DC)
, vol.267
, pp. 883-885
-
-
Miyamoto, S.1
Akiyama, S.K.2
Yamada, K.M.3
-
28
-
-
0033520312
-
Contact-dependent growth inhibition and apoptosis of epidermal growth factor (EGF) receptor-expressing cells by the membrane-anchored form of heparin-binding EGF-like growth factor
-
Iwamoto R, Handa K, Mekada E. Contact-dependent growth inhibition and apoptosis of epidermal growth factor (EGF) receptor-expressing cells by the membrane-anchored form of heparin-binding EGF-like growth factor. J Biol Chem 1999;274:25906-12.
-
(1999)
J Biol Chem
, vol.274
, pp. 25906-25912
-
-
Iwamoto, R.1
Handa, K.2
Mekada, E.3
-
29
-
-
0026425674
-
Experimental antitumor activity of taxotere (RP 56976, NSC 628503), a Taxol analogue
-
Bissery MC, Guenard D, Gueritte-Voegelein F, Lavelle F. Experimental antitumor activity of taxotere (RP 56976, NSC 628503), a Taxol analogue. Cancer Res 1991;51:4845-52.
-
(1991)
Cancer Res
, vol.51
, pp. 4845-4852
-
-
Bissery, M.C.1
Guenard, D.2
Gueritte-Voegelein, F.3
Lavelle, F.4
-
30
-
-
0037474724
-
Expression of lysophosphatidic acid receptors and vascular endothelial growth factor mediating lysophosphatidic acid in the development of human ovarian cancer
-
Fujita T, Miyamoto S, Onoyama I, et al. Expression of lysophosphatidic acid receptors and vascular endothelial growth factor mediating lysophosphatidic acid in the development of human ovarian cancer. Cancer Lett 2003;192:161-9.
-
(2003)
Cancer Lett
, vol.192
, pp. 161-169
-
-
Fujita, T.1
Miyamoto, S.2
Onoyama, I.3
-
31
-
-
0033304670
-
Amphiregulin is coordinately expressed with heparin-binding epidermal growth factor-like growth factor in the interstitial smooth muscle of the human prostate
-
Adam RM, Borer JG, Williams J, Eastham JA, Loughlin KR, Freeman MR. Amphiregulin is coordinately expressed with heparin-binding epidermal growth factor-like growth factor in the interstitial smooth muscle of the human prostate. Endocrinology 1999;140:5866-75.
-
(1999)
Endocrinology
, vol.140
, pp. 5866-5875
-
-
Adam, R.M.1
Borer, J.G.2
Williams, J.3
Eastham, J.A.4
Loughlin, K.R.5
Freeman, M.R.6
-
32
-
-
0034007763
-
Cell surface activities of the human type 2b phosphatidic acid phosphatase
-
Ishikawa T, Kai M, Wada I, Kanoh H. Cell surface activities of the human type 2b phosphatidic acid phosphatase. J Biochem (Tokyo) 2000;127:645-51.
-
(2000)
J Biochem (Tokyo)
, vol.127
, pp. 645-651
-
-
Ishikawa, T.1
Kai, M.2
Wada, I.3
Kanoh, H.4
-
33
-
-
0037374562
-
The human lipid phosphate phosphatase-3 decreases the growth, survival, and tumorigenesis of ovarian cancer cells: Validation of the lysophosphatidic acid signaling cascade as a target for therapy in ovarian cancer
-
Tanyi JL, Morris AJ, Wolf JK, et al. The human lipid phosphate phosphatase-3 decreases the growth, survival, and tumorigenesis of ovarian cancer cells: validation of the lysophosphatidic acid signaling cascade as a target for therapy in ovarian cancer. Cancer Res 2003;63:1073-82.
-
(2003)
Cancer Res
, vol.63
, pp. 1073-1082
-
-
Tanyi, J.L.1
Morris, A.J.2
Wolf, J.K.3
-
34
-
-
0028860250
-
Diphtheria toxin binds to the epidermal growth factor (EGF)-like domain of human heparin-binding EGF-like growth factor/diphtheria toxin receptor and inhibits specifically its mitogenic activity
-
Mitamura T, Higashiyama S, Taniguchi N, Klagsbrun M, Mekada E. Diphtheria toxin binds to the epidermal growth factor (EGF)-like domain of human heparin-binding EGF-like growth factor/diphtheria toxin receptor and inhibits specifically its mitogenic activity. J Biol Chem 1995;270:1015-9.
-
(1995)
J Biol Chem
, vol.270
, pp. 1015-1019
-
-
Mitamura, T.1
Higashiyama, S.2
Taniguchi, N.3
Klagsbrun, M.4
Mekada, E.5
-
35
-
-
1642351380
-
In vivo establishment and characterization of a paclitaxel-resistant human ovarian cancer cell line showing enhanced growth properties and drug-resistance only in vivo
-
Okugawa K, Kobayashi H, Hirakawa T, et al. In vivo establishment and characterization of a paclitaxel-resistant human ovarian cancer cell line showing enhanced growth properties and drug-resistance only in vivo. J Cancer Res Clin Oncol 2004;130:178-86.
-
(2004)
J Cancer Res Clin Oncol
, vol.130
, pp. 178-186
-
-
Okugawa, K.1
Kobayashi, H.2
Hirakawa, T.3
-
36
-
-
0035839427
-
A dual signaling cascade that regulates the ectodomain shedding of heparin-binding epidermal growth factor-like growth factor
-
Umata T, Hirata M, Takahashi T, et al. A dual signaling cascade that regulates the ectodomain shedding of heparin-binding epidermal growth factor-like growth factor. J Biol Chem 2001;276:30475-82.
-
(2001)
J Biol Chem
, vol.276
, pp. 30475-30482
-
-
Umata, T.1
Hirata, M.2
Takahashi, T.3
-
37
-
-
0034083409
-
Constitutive and lysophosphatidic acid (LPA)-induced LPA production: Role of phospholipase D and phospholipase A2
-
Eder AM, Sasagawa T, Mao M, Aoki J, Mills GB. Constitutive and lysophosphatidic acid (LPA)-induced LPA production: role of phospholipase D and phospholipase A2. Clin Cancer Res 2000;6:2482-91.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 2482-2491
-
-
Eder, A.M.1
Sasagawa, T.2
Mao, M.3
Aoki, J.4
Mills, G.B.5
-
38
-
-
0026748744
-
Identification of a putative membrane receptor for the bioactive phospholipid, lysophosphatidic acid
-
van der Bend RL, Brunner J, Jalink K, et al. Identification of a putative membrane receptor for the bioactive phospholipid, lysophosphatidic acid. EMBO J 1992;11:2495-501.
-
(1992)
EMBO J
, vol.11
, pp. 2495-2501
-
-
Van Der Bend, R.L.1
Brunner, J.2
Jalink, K.3
-
39
-
-
0032496366
-
Identification of a novel human phosphatidic acid phosphatase type 2 isoform
-
Hooks SB, Ragan SP, Lynch KR. Identification of a novel human phosphatidic acid phosphatase type 2 isoform. FEBS Lett 1998;427:188-92.
-
(1998)
FEBS Lett
, vol.427
, pp. 188-192
-
-
Hooks, S.B.1
Ragan, S.P.2
Lynch, K.R.3
-
40
-
-
0025341727
-
TGF alpha overexpression in transgenic mice induces liver neoplasia and abnormal development of the mammary gland and pancreas
-
Jhappan C, Stahle C, Harkins RN, et al. TGF alpha overexpression in transgenic mice induces liver neoplasia and abnormal development of the mammary gland and pancreas. Cell 1990;61:1137-46.
-
(1990)
Cell
, vol.61
, pp. 1137-1146
-
-
Jhappan, C.1
Stahle, C.2
Harkins, R.N.3
-
41
-
-
0025297086
-
Overexpression of TGF alpha in transgenic mice: Induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast
-
Sandgren EP, Luetteke NC, Palmiter RD, Brinster RL, Lee DC. Overexpression of TGF alpha in transgenic mice: induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast. Cell 1990;61:1121-35.
-
(1990)
Cell
, vol.61
, pp. 1121-1135
-
-
Sandgren, E.P.1
Luetteke, N.C.2
Palmiter, R.D.3
Brinster, R.L.4
Lee, D.C.5
-
42
-
-
0033547421
-
Antisense expression for amphiregulin suppresses tumorigenicity of a transformed human breast epithelial cell line
-
Ma L, Gauville C, Berthois Y, et al. Antisense expression for amphiregulin suppresses tumorigenicity of a transformed human breast epithelial cell line. Oncogene 1999;18:6513-20.
-
(1999)
Oncogene
, vol.18
, pp. 6513-6520
-
-
Ma, L.1
Gauville, C.2
Berthois, Y.3
-
43
-
-
0034785693
-
Fatty acid composition of lysophosphatidic acid and lysophosphatidylinositol in plasma from patients with ovarian cancer and other gynecological diseases
-
Shen Z, Wu M, Elson P, et al. Fatty acid composition of lysophosphatidic acid and lysophosphatidylinositol in plasma from patients with ovarian cancer and other gynecological diseases. Gynecol Oncol 2001;83:25-30.
-
(2001)
Gynecol Oncol
, vol.83
, pp. 25-30
-
-
Shen, Z.1
Wu, M.2
Elson, P.3
-
45
-
-
0032442191
-
Phorbol 12-myristate 13-acetate stimulates lysophosphatidic acid secretion from ovarian and cervical cancer cells but not from breast or leukemia cells
-
Shen Z, Belinson J, Morton RE, Xu Y. Phorbol 12-myristate 13-acetate stimulates lysophosphatidic acid secretion from ovarian and cervical cancer cells but not from breast or leukemia cells. Gynecol Oncol 1998;71:364-8.
-
(1998)
Gynecol Oncol
, vol.71
, pp. 364-368
-
-
Shen, Z.1
Belinson, J.2
Morton, R.E.3
Xu, Y.4
-
46
-
-
0036140653
-
Lack of significant differences in the corrected activity of lysophospholipase D, producer of phospholipid mediator lysophosphatidic acid, in incubated serum from women with and without ovarian tumors
-
Tokumura A, Tominaga K, Yasuda K, et al. Lack of significant differences in the corrected activity of lysophospholipase D, producer of phospholipid mediator lysophosphatidic acid, in incubated serum from women with and without ovarian tumors. Cancer (Phila) 2002;94:141-51.
-
(2002)
Cancer (Phila)
, vol.94
, pp. 141-151
-
-
Tokumura, A.1
Tominaga, K.2
Yasuda, K.3
-
47
-
-
0028931859
-
Stimulation of phospholipase D by epidermal growth factor requires protein kinase C activation in Swiss 3T3 cells
-
Yeo EJ, Exton JH. Stimulation of phospholipase D by epidermal growth factor requires protein kinase C activation in Swiss 3T3 cells. J Biol Chem 1995;270:3980-8.
-
(1995)
J Biol Chem
, vol.270
, pp. 3980-3988
-
-
Yeo, E.J.1
Exton, J.H.2
-
48
-
-
0030836586
-
Properties and regulation of cytosolic phospholipase A2
-
Leslie CC. Properties and regulation of cytosolic phospholipase A2. J Biol Chem 1997;272:16709-12.
-
(1997)
J Biol Chem
, vol.272
, pp. 16709-16712
-
-
Leslie, C.C.1
-
49
-
-
0028037574
-
Heparin-binding epidermal growth factor-like growth factor is an autocrine growth factor for human keratinocytes
-
Hashimoto K, Higashiyama S, Asada H, et al. Heparin-binding epidermal growth factor-like growth factor is an autocrine growth factor for human keratinocytes. J Biol Chem 1994;269:20060-6.
-
(1994)
J Biol Chem
, vol.269
, pp. 20060-20066
-
-
Hashimoto, K.1
Higashiyama, S.2
Asada, H.3
-
50
-
-
0037453001
-
Heparin-binding EGF-like growth factor and ErbB signaling is essential for heart function
-
Iwamoto R, Yamazaki S, Asakura M, et al. Heparin-binding EGF-like growth factor and ErbB signaling is essential for heart function. Proc Natl Acad Sci USA 2003;100:3221-6.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 3221-3226
-
-
Iwamoto, R.1
Yamazaki, S.2
Asakura, M.3
|