The ECM proteoglycan decorin links desmoplasia and inflammation in chronic pancreatitis

Journal of Clinical Pathology

Volumn 59, Issue 1, 2006, Pages 21-27

  Koninger J ^a   Giese, N A ^a   Bartel, M ^a   Di Mola, F F ^a   Berberat, P O ^a   Di Sebastiano, P ^a   Giese, T ^a   Buchler M W ^a   Friess, H ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; DECORIN; INTERLEUKIN 1BETA; MOLECULAR MARKER; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEOGLYCAN; TUMOR NECROSIS FACTOR ALPHA;

ADOLESCENT; ADULT; AGED; ARTICLE; BIOPSY TECHNIQUE; CHRONIC PANCREATITIS; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DESMOPLASIA; EXTRACELLULAR MATRIX; FEMALE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; INFLAMMATION; INFLAMMATORY CELL; MACROPHAGE ACTIVATION; MALE; MONONUCLEAR CELL; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RECURRENT DISEASE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RISK FACTOR; WESTERN BLOTTING;

ADOLESCENT; ADULT; AGED; BLOTTING, WESTERN; CELLS, CULTURED; CHEMOKINE CCL2; EXTRACELLULAR MATRIX; EXTRACELLULAR MATRIX PROTEINS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOENZYME TECHNIQUES; LEUKOCYTES, MONONUCLEAR; MALE; MIDDLE AGED; PANCREAS; PANCREATITIS, CHRONIC; PROTEOGLYCANS; RECURRENCE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; UP-REGULATION;

EID: 30444440918     PISSN: 00219746     EISSN: None     Source Type: Journal    
DOI: 10.1136/jcp.2004.023135     Document Type: Article

References (42)

1. Shrikhande SV, Martignoni ME, Shrikhande M, et al. Comparison of histological features and inflammatory cell reaction in alcoholic, idiopathic and tropical chronic pancreatitis. Br J Surg 2003;90:1565-72.
2. Bookman DE, Muller M, Buchler M, et al. Pathological changes in pancreatic ducts from patients with chronic pancreatitis. Int J Pancreatol 1997;21:119-26.
3. Emmrich J, Weber I, Nausch M, et al. Immunohistochemical characterization of the pancreatic cellular infiltrate in normal pancreas, chronic pancreatitis and pancreatic carcinoma. Digestion 1998;59:192-8.
4. Bateman AC, Turner SM, Thomas KS, et al. Apoptosis and proliferation of acinar and islet cells in chronic pancreatitis: evidence for differential cell loss mediating preservation of islet function. Gut 2002;50:542-8.
5. Goecke H, Forssmann U, Uguccioni M, et al. Macrophages infiltrating the tissue in chronic pancreatitis express the chemokine receptor CCR5. Surgery 2000;128:806-14.
6. Hunger RE, Mueller C, Z'Graggen K, et al. Cytotoxic cells are activated in cellular infiltrates of alcoholic chronic pancreatitis. Gastroenterology 1997;112:1656-63.
7. Luster AD. Chemokines-chemotactic cytokines that mediate inflammation. N Engl J Med 1998;338:436-45.
8. Saurer L, Reber P, Schaffner T, et al. Differential expression of chemokines in normal pancreas and in chronic pancreatitis. Gastroenterology 2000;118:356-67.
9. Kresse H, Schonherr E. Proteoglycans of the extracellular matrix and growth control. J Cell Physiol 2001;189:266-74.
10. Okamura Y, Watari M, Jerud ES, et al. The extra domain A of fibronectin activates Toll-like receptor 4. J Biol Chem 2001;276:10229-33.
11. Ameye L, Young MF. Mice deficient in small leucine-rich proteoglycans: novel in vivo models For osteoporosis, osteoarthritis, Ehlers-Danlos syndrome, muscular dystrophy, and corneal diseases. Glycobiology 2002;12:107R-16R.
12. Danielson KG, Baribault H, Holmes DF, et al. Targeted disruption of decorin leads to abnormal collagen fibril morphology and skin fragility. J Cell Biol 1997;136:729-43.
13. Yamaguchi Y, Mann DM, Ruoslahti E. Negative regulation of transforming growth factor-beta by the proteoglycan decorin. Nature 1990;346:281-4.
14. Comalada M, Cardo M, Xaus J, et al. Decorin reverses the repressive effect of autocrine-produced TGF-beta on mouse macrophage activation. J Immunol 2003;170:4450-6.
15. Xaus J, Comalada M, Cardo M, et al. Decorin inhibits macrophage colony-stimulating factor proliferation of macrophages and enhances cell survival through induction of p27(Kipl) and p21(Wafl). Blood 2001;98:2124-33.
16. Schmidt G, Robenek H, Harrach B, et al. Interaction of small dermatan sulfate proteoglycan from fibroblasts with fibronectin. J Cell Biol 1987;104:1683-91.
17. Santiago-Garcia J, Kodama T, Pitas RE. The class A scavenger receptor binds to proteoglycans and mediates adhesion of macrophages to the extracellular matrix. J Biol Chem 2003;278:6942-6.
18. Guo J, Kleeff J, Li J, et al. Expression and functional significance of CDC25B in human pancreatic ductal adenocarcinoma. Oncogene 2004;23:71-81.
19. Fukui N, Fukuda A, Kojima K, et al. Suppression of fibrous adhesion by proteoglycan decorin. J Orthop Res 2001;19:456-62.
20. Nakamura N, Hart DA, Boorman RS, et al. Decorin antisense gene therapy improves functional healing of early rabbit ligament scar with enhanced collagen fibrillogenesis in vivo. J Orthop Res 2000;18:517-23.
21. Giri SN, Hyde DM, Braun RK, et al. Antifibrotic effect of decorin in a bleomycin hamster model of lung fibrosis. Biochem Pharmacol 1997;54:1205-16.
22. Sato K, Li Y, Foster W, et al. Improvement of muscle healing through enhancement of muscle regeneration and prevention of fibrosis. Muscle Nerve 2003;28:365-72.
23. Dudas J, Kovalszky I, Gallai M, et al. Expression of decorin, transforming growth factor-beta 1, tissue inhibitor metalloproteinase 1 and 2, and type IV collagenases in chronic hepatitis. Am J Clin Pathol 2001;115:725-35.
24. Kovalszky II, Nagy JO, Gallai M, et al. Altered proteoglycan gene expression in human biliary cirrhosis. Pathol Oncol Res 1997;3:51-8.
25. Hogemann B, Edel G, Schwarz K, et al. Expression of biglycan, decorin and proteoglycan-100/CSF-1 in normal and fibrotic human liver. Pathol Res Pract 1997;193:747-51.
26. Schaefer L, Raslik I, Grone HJ, et al. Small proteoglycans in human diabetic nephropathy: discrepancy between glomerular expression and protein accumulation of decorin, biglycan, lumican, and fibromodulin. FASEB J 2001;15:559-61.
27. Cs-Szabo G, Ragasa-San Juan D, Turumella V, et al. Changes in mRNA and protein levels of proteoglycans of the anulus fibrosus and nucleus pulposus during intervertebral disc degeneration. Spine 2002;27:2212-19.
28. Malmstrom J, Larsen K, Hansson L, et al. Proteoglycan and proteome profiling of central human pulmonary fibrotic tissue utilizing miniaturized sample preparation: a feasibility study. Proteomics 2002;2:394-404.
29. Bensadoun ES, Burke AK, Hogg JC, et al. Proteoglycans in granulomatous lung diseases. Eur Respir J 1997;10:2731-7.
30. Kovalszky I, Nagy P, Szende B, et al. Experimental and human liver fibrogenesis. Scand J Gastroenterol Suppl 1998;228:51-5.
31. Bissell MJ, Radisky D. Putting tumours in context. Nat Rev Cancer 2001;1:46-54.
32. Corbett SA, Schwarzbauer JE. Fibronectin-fibrin cross-linking; a regulator of cell behavior. Trends Cardiovasc Med 1998;8:357-62.
33. Beger HG, Schlosser W, Friess HM, et al. Duodenum-preserving head resection in chronic pancreatitis changes the natural course of the disease: a single-center 26-year experience. Ann Surg 1999;230:512-19.
34. Hartel M, Tempia-Caliera AA, Wente MN, et al. Evidence-based surgery in chronic pancreatitis. Langenbecks Arch Surg 2003;388:132-9.
35. Daly C, Rollins BJ. Monocyte chemoattractant protein-1 (CCL2) in inflammatory disease and adaptive immunity: therapeutic opportunities and controversies. Microcirculation 2003;10:247-57.
36. Ross EL, D'Cruz D, Morrow WJ. Localized monocyte chemotactic protein-1 production correlates with T cell infiltration of synovium in patients with psoriatic arthritis. J Rheumatol 2000;27:2432-43.
37. Ellingsen T, Buus A, Stengaard-Pedersen K. Plasma monocyte chemoattractant protein 1 is a marker for joint inflammation in rheumatoid arthritis. J Rheumatol 2001;28:41-6.
38. Charo IF, Peters W. Chemokine receptor 2 (CCR2) in atherosclerosis, infectious diseases, and regulation of T cell polarization. Microcirculation 2003;10:259-64.
39. Biswas SK, Sodhi A. In vitro activation of murine peritoneal macrophages by monocyte chemoattractant protein-1: upregulation of CD11b, production of proinflammatory cytokines, and the signal transduction pathway. J Interferon Cytokine Res 2002;22:527-38.
40. Luther SA, Cyster JG. Chemokines as regulators of T cell differentiation. Nat Immunol 2001;2:102-7.
41. Troynor TR, Herring AC, Dorf ME, et al. Differential roles of CC chemokine ligand 2/monocyte chemotactic protein-1 and CCR2 in the development of T1 immunity. J Immunol 2002;168:4659-66.
42. Davies JE, Tang X, Denning JW, et al. Decorin suppresses neurocan, brevican, phosphacan and NG2 expression and promotes axon growth across adult rat spinal cord injuries, Eur J Neurosci 2004;19:1226-42.